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The map label for this gene is ribD [C]

Identifier: 15668852

GI number: 15668852

Start: 596961

End: 597635

Strand: Reverse

Name: ribD [C]

Synonym: MJ0671

Alternate gene names: 15668852

Gene position: 597635-596961 (Counterclockwise)

Preceding gene: 15668853

Following gene: 15668851

Centisome position: 35.89

GC content: 32.3

Gene sequence:

>675_bases
TTGGTGATGGTAATGGAAAAAAAGCCATACATTATCTCAAATGTAGGCATGACCTTAGATGGAAAGTTAGCTACTATAAA
CAACGATTCGAGAATTTCATGCGAAGAGGATTTAATAAGAGTTCATAAGATTAGGGCTAATGTAGATGGGATTATGGTTG
GTATTGGGACTGTTTTAAAGGACGACCCAAGATTAACAGTTCATAAGATTAAAAGTGATAGAAATCCTGTTAGAATAGTT
GTTGATAGTAAGCTAAGAGTTCCATTAAATGCAAGGGTTTTAAATAAAGATGCTAAAACTATTATAGCAACAACAGAAGA
TACTAATGAAGAGAAAGAAAAGAAAATAAAAATCTTAGAAGATATGGGAGTTGAAGTAGTTAAATGTGGTAGAGGAAAGG
TAGATTTAAAAAAATTGATGGATATTTTATATGATAAAGGGATAAAAAGCATCTTATTGGAAGGAGGAGGAACTTTAAAC
TGGGGTATGTTTAAAGAGGGCTTAGTTGATGAGGTCTCCGTCTATATAGCTCCAAAAATATTTGGTGGGAAAGAAGCCCC
AACATATGTAGATGGGGAAGGGTTTAAAACAGTAGATGAGTGTGTTAAATTAGAATTAAAAAACTTCTATAGGTTAGGAG
AAGGAATTGTATTGGAATTTAAAGTAAAGAAATAA

Upstream 100 bases:

>100_bases
TATCTGCAGCTGTAATAACTCTATATTCCATTCTTTATCTATAAAATTTAGCTATCATTTAGAATATAAAACTTAAATTT
TATTAACTAAACATTTAAAA

Downstream 100 bases:

>100_bases
ATATAATGTGAGAGTTATGCTTCCAAACAAAAAAGCCTTAGAAATTATTAGAAAGTATATGAAAATTTACAATGGAAAGA
ATGAAAAAGATATTAAAGAG

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: HTP reductase

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MVMVMEKKPYIISNVGMTLDGKLATINNDSRISCEEDLIRVHKIRANVDGIMVGIGTVLKDDPRLTVHKIKSDRNPVRIV
VDSKLRVPLNARVLNKDAKTIIATTEDTNEEKEKKIKILEDMGVEVVKCGRGKVDLKKLMDILYDKGIKSILLEGGGTLN
WGMFKEGLVDEVSVYIAPKIFGGKEAPTYVDGEGFKTVDECVKLELKNFYRLGEGIVLEFKVKK

Sequences:

>Translated_224_residues
MVMVMEKKPYIISNVGMTLDGKLATINNDSRISCEEDLIRVHKIRANVDGIMVGIGTVLKDDPRLTVHKIKSDRNPVRIV
VDSKLRVPLNARVLNKDAKTIIATTEDTNEEKEKKIKILEDMGVEVVKCGRGKVDLKKLMDILYDKGIKSILLEGGGTLN
WGMFKEGLVDEVSVYIAPKIFGGKEAPTYVDGEGFKTVDECVKLELKNFYRLGEGIVLEFKVKK
>Mature_224_residues
MVMVMEKKPYIISNVGMTLDGKLATINNDSRISCEEDLIRVHKIRANVDGIMVGIGTVLKDDPRLTVHKIKSDRNPVRIV
VDSKLRVPLNARVLNKDAKTIIATTEDTNEEKEKKIKILEDMGVEVVKCGRGKVDLKKLMDILYDKGIKSILLEGGGTLN
WGMFKEGLVDEVSVYIAPKIFGGKEAPTYVDGEGFKTVDECVKLELKNFYRLGEGIVLEFKVKK

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family

Homologues:

Organism=Escherichia coli, GI1786616, Length=225, Percent_Identity=30.6666666666667, Blast_Score=100, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIB7_METJA (Q58085)

Other databases:

- EMBL:   L77117
- PIR:   G64383
- RefSeq:   NP_247655.1
- PDB:   2AZN
- PDBsum:   2AZN
- ProteinModelPortal:   Q58085
- SMR:   Q58085
- GeneID:   1451537
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0671
- NMPDR:   fig|243232.1.peg.692
- TIGR:   MJ0671
- HOGENOM:   HBG668075
- OMA:   ISCEEDL
- ProtClustDB:   PRK05625
- BioCyc:   MetaCyc:MONOMER-14596
- BioCyc:   MJAN243232:MJ_0671-MONOMER
- BRENDA:   1.1.1.193
- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734
- PANTHER:   PTHR11079:SF10
- TIGRFAMs:   TIGR01508
- TIGRFAMs:   TIGR00227

Pfam domain/function: PF01872 RibD_C

EC number: =1.1.1.193

Molecular weight: Translated: 25038; Mature: 25038

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMVMEKKPYIISNVGMTLDGKLATINNDSRISCEEDLIRVHKIRANVDGIMVGIGTVLK
CEEEEECCCEEEEECCEEECCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHCC
DDPRLTVHKIKSDRNPVRIVVDSKLRVPLNARVLNKDAKTIIATTEDTNEEKEKKIKILE
CCCCEEEEEECCCCCCEEEEECCEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHH
DMGVEVVKCGRGKVDLKKLMDILYDKGIKSILLEGGGTLNWGMFKEGLVDEVSVYIAPKI
HCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCEEECCHHHCCCHHHEEEEEEEEE
FGGKEAPTYVDGEGFKTVDECVKLELKNFYRLGEGIVLEFKVKK
ECCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MVMVMEKKPYIISNVGMTLDGKLATINNDSRISCEEDLIRVHKIRANVDGIMVGIGTVLK
CEEEEECCCEEEEECCEEECCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHCC
DDPRLTVHKIKSDRNPVRIVVDSKLRVPLNARVLNKDAKTIIATTEDTNEEKEKKIKILE
CCCCEEEEEECCCCCCEEEEECCEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHH
DMGVEVVKCGRGKVDLKKLMDILYDKGIKSILLEGGGTLNWGMFKEGLVDEVSVYIAPKI
HCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCEEECCHHHCCCHHHEEEEEEEEE
FGGKEAPTYVDGEGFKTVDECVKLELKNFYRLGEGIVLEFKVKK
ECCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087