Click here to switch to the map view.

The map label for this gene is 15668737

Identifier: 15668737

GI number: 15668737

Start: 492568

End: 493185

Strand: Reverse

Name: 15668737

Synonym: MJ0557

Alternate gene names: NA

Gene position: 493185-492568 (Counterclockwise)

Preceding gene: 15668738

Following gene: 15668736

Centisome position: 29.62

GC content: 26.86

Gene sequence:

>618_bases
ATGACATATAATATAATTTTAGCTAAATCAGCTCTTGAACTAATCCCAGAAGAGATAAAAAATAAAATAAGAAAGTCCAG
AGTTTATAAATATGATATTTTGGATTCTAACTATCACTATAAGGCAATGGAAAAACTAAAAGATAAAGAGATGAGAGGAA
GACCAGATATCATCCACATATCACTTTTAAATATATTAGATAGTCCAATAAATCATGAAAAAAAGCTAAACATCTATATT
CATACTTATGACGATAAGGTTTTAAAAATAAATCCTGAAACAAGATTGCCAAGGAATTACTTTAGGTTTTTGGGAGTTAT
GGAAAAGGTTTTAAAAGGAGAAAGAAATCATTTAATAAAAATGGAAGAAAAAACGTTAGAAGATTTATTAAACGAGATAA
ATGCTAAAAAAATAGCTATAATGACCAAAACTGGGAAATTAACTCATCCAAAGCTTTTAAAGGAATATGATACTTTTATA
ATAGGCGGATTCCCGTATGGAAAGTTAAAAATTAATAAAGAAAAAGTTTTTGGAGATATTAAGGAAATCTCCATTTATAA
TAAAGGTTTAATGGCTTGGACTGTTTGTGGGATAATTTGCTATTCATTAAGCTTTTAA

Upstream 100 bases:

>100_bases
TGGAAAAATGGCTGAAAAAGTCATTAAAAAGCTTGATAATGCGAAAATTAGCTATACTGTATTAGATGCCACAAAAGAAA
ATAAATAATGAGGAAGGAAA

Downstream 100 bases:

>100_bases
AATTTTAAATTATATTTTTATTAGATGGTAAGTTTAGAAATTTAAAGTGAATTAATAGTAACAATAATTTATTTAAACCA
TGACAACAAAATTCTTAATT

Product: ribosome biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYI
HTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFI
IGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF

Sequences:

>Translated_205_residues
MTYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYI
HTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFI
IGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
>Mature_204_residues
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIH
TYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFII
GGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF

Specific function: Involved in ribosomal biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing

COG id: COG1756

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NEP1 family

Homologues:

Organism=Homo sapiens, GI194328699, Length=202, Percent_Identity=27.7227722772277, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17555712, Length=186, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323215, Length=183, Percent_Identity=27.8688524590164, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639698, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NEP1_METJA (Q57977)

Other databases:

- EMBL:   L77117
- PIR:   E64369
- RefSeq:   NP_247536.1
- PDB:   3BBD
- PDB:   3BBE
- PDB:   3BBH
- PDBsum:   3BBD
- PDBsum:   3BBE
- PDBsum:   3BBH
- ProteinModelPortal:   Q57977
- SMR:   Q57977
- GeneID:   1451422
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0557
- NMPDR:   fig|243232.1.peg.573
- TIGR:   MJ0557
- HOGENOM:   HBG512786
- OMA:   YNIILAK
- ProtClustDB:   PRK04171
- BioCyc:   MJAN243232:MJ_0557-MONOMER
- HAMAP:   MF_00554
- InterPro:   IPR005304
- PANTHER:   PTHR12636

Pfam domain/function: PF03587 EMG1

EC number: NA

Molecular weight: Translated: 24083; Mature: 23952

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHI
CEEEEEEHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEE
SLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIK
EHHHHHCCCCCCCEEEEEEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
MEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDI
EHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCEEECCCCCCEEEECHHHHHCCH
KEISIYNKGLMAWTVCGIICYSLSF
HHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHI
EEEEEEHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEE
SLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIK
EHHHHHCCCCCCCEEEEEEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
MEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDI
EHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCEEECCCCCCEEEECHHHHHCCH
KEISIYNKGLMAWTVCGIICYSLSF
HHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087