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The map label for this gene is fixC [C]

Identifier: 15668712

GI number: 15668712

Start: 467607

End: 468782

Strand: Reverse

Name: fixC [C]

Synonym: MJ0532

Alternate gene names: 15668712

Gene position: 468782-467607 (Counterclockwise)

Preceding gene: 15668713

Following gene: 15668709

Centisome position: 28.16

GC content: 34.78

Gene sequence:

>1176_bases
ATGAGAGAGTTAAATGATGTATATGATGTAGTGGTTGTTGGAGCAGGTCCCGGAGGAAGTATGGCAAGTTATGCATCAGC
AAAGAATGGAGCTAAAACACTATTAATTGAGAAATCTCAAGAGATTGGTGAGCCAGTTAGGTGTGCTGAGGCAATTCCAT
CAATAGAGGAATTTGGATTAAAACCAGAACCAGAGTTTGTTAGAAACATTATTAAGGGAGGAATTTTATTTTCTCCTTCT
GGAAAAAAAGTTACAGTAACTCAAGATAAGGCTCAAGGATATGTAGTTGAGAGAAAAATTTTTGATAAATATTTGGCTAT
AAGGGCAGCTAAAGCAGGAGCTAAAGTAGCAGTAAAAACAACAGCTATTGGTTTAGAGAGGGACGGAGATTATTGGAATG
TTATAGTTGAATTTTTAGGAGAGGAGTATGTTATAAAAACTAAAGTGGTTATAGCTGCTGATGGTGTTGAGAGCAATATA
GCTGAATATGCTGGTTTAAAGGCAAAGAAAAAGCCATTGGAGATTTGCTCCTGTGCTGAATATGAGATGACAAATGTTGA
ATTGTTGGATAAAAATATGATGGAATTCTATTTTGGTAATGAAGTGGCTCCAGGAGGGTATGTTTGGATATTCCCCAAAG
GAGAAACAGCTAATGTTGGTTTGGGAGTTAGAGATAAAAAGAAGAAGGCAATAGAATATTTAGAAGAGTTCATAGAAAAT
GGTTTAGCTAAAGATAGGTTAAAGGATGCAACACCAATAGAATTCAAAGTTGGAGGAGCTCCTGTTTCTGGCCCTATAGA
AAAAACCTATACTGATGGTCTTTTAGTTGTGGGGGATGCTGCTGGGCAGATAAGCCCATTAACTGGTGGAGGAATTTATT
TAGCTATGGATTGTGGATTAATAGCTGGAGAAGTAGCAAGTAAAGCTATAAAATTAAATGATTGGAGTGAAGAAACCCTA
AAAGAATATGAAAGAAGATGGAAAGAAAAGCATTATGAATATTTAATGAGCCATTTAAAGTATAGAAAAATCTTAGAGAA
AATGAGTGATGATGAGTTAGATGCTTTAGCAGAAGCTTTAGGAGAAAGTTTAGACGGCATTGACTTGAAAAAATTTGTCA
AGAGAATAATAACTAAAAAACCATCACTTTTAAAATACTTTAAGGATTTATTATAA

Upstream 100 bases:

>100_bases
TCAATTTGATAGAACATATTATAGTTATTGATGAAAAAAAGTGTAATAACTGTAAGTTATGCACAATAGTATGTCCATTA
AATGCATTAGAGGGGGAATG

Downstream 100 bases:

>100_bases
TTTTATTCTTTCTTTGGTTTTTTAACTACTAAAACTGGACAGTGTGCATTTTTAATAACTCTCTCAGCTACACTTCCCAA
TAATATTCTTTCCAATCCTG

Product: bacteriochlorophyll synthase 43 kDa subunit ChlP

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRELNDVYDVVVVGAGPGGSMASYASAKNGAKTLLIEKSQEIGEPVRCAEAIPSIEEFGLKPEPEFVRNIIKGGILFSPS
GKKVTVTQDKAQGYVVERKIFDKYLAIRAAKAGAKVAVKTTAIGLERDGDYWNVIVEFLGEEYVIKTKVVIAADGVESNI
AEYAGLKAKKKPLEICSCAEYEMTNVELLDKNMMEFYFGNEVAPGGYVWIFPKGETANVGLGVRDKKKKAIEYLEEFIEN
GLAKDRLKDATPIEFKVGGAPVSGPIEKTYTDGLLVVGDAAGQISPLTGGGIYLAMDCGLIAGEVASKAIKLNDWSEETL
KEYERRWKEKHYEYLMSHLKYRKILEKMSDDELDALAEALGESLDGIDLKKFVKRIITKKPSLLKYFKDLL

Sequences:

>Translated_391_residues
MRELNDVYDVVVVGAGPGGSMASYASAKNGAKTLLIEKSQEIGEPVRCAEAIPSIEEFGLKPEPEFVRNIIKGGILFSPS
GKKVTVTQDKAQGYVVERKIFDKYLAIRAAKAGAKVAVKTTAIGLERDGDYWNVIVEFLGEEYVIKTKVVIAADGVESNI
AEYAGLKAKKKPLEICSCAEYEMTNVELLDKNMMEFYFGNEVAPGGYVWIFPKGETANVGLGVRDKKKKAIEYLEEFIEN
GLAKDRLKDATPIEFKVGGAPVSGPIEKTYTDGLLVVGDAAGQISPLTGGGIYLAMDCGLIAGEVASKAIKLNDWSEETL
KEYERRWKEKHYEYLMSHLKYRKILEKMSDDELDALAEALGESLDGIDLKKFVKRIITKKPSLLKYFKDLL
>Mature_391_residues
MRELNDVYDVVVVGAGPGGSMASYASAKNGAKTLLIEKSQEIGEPVRCAEAIPSIEEFGLKPEPEFVRNIIKGGILFSPS
GKKVTVTQDKAQGYVVERKIFDKYLAIRAAKAGAKVAVKTTAIGLERDGDYWNVIVEFLGEEYVIKTKVVIAADGVESNI
AEYAGLKAKKKPLEICSCAEYEMTNVELLDKNMMEFYFGNEVAPGGYVWIFPKGETANVGLGVRDKKKKAIEYLEEFIEN
GLAKDRLKDATPIEFKVGGAPVSGPIEKTYTDGLLVVGDAAGQISPLTGGGIYLAMDCGLIAGEVASKAIKLNDWSEETL
KEYERRWKEKHYEYLMSHLKYRKILEKMSDDELDALAEALGESLDGIDLKKFVKRIITKKPSLLKYFKDLL

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily

Homologues:

Organism=Escherichia coli, GI1786227, Length=360, Percent_Identity=28.0555555555556, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787991, Length=428, Percent_Identity=24.0654205607477, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGR_METJA (Q57952)

Other databases:

- EMBL:   L77117
- PIR:   D64366
- RefSeq:   NP_247511.1
- ProteinModelPortal:   Q57952
- SMR:   Q57952
- GeneID:   1451397
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0532
- NMPDR:   fig|243232.1.peg.548
- TIGR:   MJ0532
- HOGENOM:   HBG626912
- OMA:   VILARND
- ProtClustDB:   CLSK876233
- BioCyc:   MJAN243232:MJ_0532-MONOMER
- HAMAP:   MF_01287
- InterPro:   IPR011777
- InterPro:   IPR002218
- InterPro:   IPR002938
- InterPro:   IPR016040
- InterPro:   IPR003042
- Gene3D:   G3DSA:3.40.50.720
- PRINTS:   PR00420
- TIGRFAMs:   TIGR02032

Pfam domain/function: PF01494 FAD_binding_3; PF01134 GIDA

EC number: NA

Molecular weight: Translated: 43094; Mature: 43094

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELNDVYDVVVVGAGPGGSMASYASAKNGAKTLLIEKSQEIGEPVRCAEAIPSIEEFGL
CCCCCCEEEEEEEECCCCCCHHHHHHCCCCCEEEEEECCHHCCCHHHHHHHCCCHHHCCC
KPEPEFVRNIIKGGILFSPSGKKVTVTQDKAQGYVVERKIFDKYLAIRAAKAGAKVAVKT
CCCHHHHHHHHHCCEEECCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEE
TAIGLERDGDYWNVIVEFLGEEYVIKTKVVIAADGVESNIAEYAGLKAKKKPLEICSCAE
EEEEECCCCCHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHHHHCCCCCCCCHHHHCCCC
YEMTNVELLDKNMMEFYFGNEVAPGGYVWIFPKGETANVGLGVRDKKKKAIEYLEEFIEN
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
GLAKDRLKDATPIEFKVGGAPVSGPIEKTYTDGLLVVGDAAGQISPLTGGGIYLAMDCGL
CCHHHHCCCCCCCEEEECCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCH
IAGEVASKAIKLNDWSEETLKEYERRWKEKHYEYLMSHLKYRKILEKMSDDELDALAEAL
HHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GESLDGIDLKKFVKRIITKKPSLLKYFKDLL
HCCCCCCCHHHHHHHHHCCCCHHHHHHHHHC
>Mature Secondary Structure
MRELNDVYDVVVVGAGPGGSMASYASAKNGAKTLLIEKSQEIGEPVRCAEAIPSIEEFGL
CCCCCCEEEEEEEECCCCCCHHHHHHCCCCCEEEEEECCHHCCCHHHHHHHCCCHHHCCC
KPEPEFVRNIIKGGILFSPSGKKVTVTQDKAQGYVVERKIFDKYLAIRAAKAGAKVAVKT
CCCHHHHHHHHHCCEEECCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEE
TAIGLERDGDYWNVIVEFLGEEYVIKTKVVIAADGVESNIAEYAGLKAKKKPLEICSCAE
EEEEECCCCCHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHHHHCCCCCCCCHHHHCCCC
YEMTNVELLDKNMMEFYFGNEVAPGGYVWIFPKGETANVGLGVRDKKKKAIEYLEEFIEN
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
GLAKDRLKDATPIEFKVGGAPVSGPIEKTYTDGLLVVGDAAGQISPLTGGGIYLAMDCGL
CCHHHHCCCCCCCEEEECCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCH
IAGEVASKAIKLNDWSEETLKEYERRWKEKHYEYLMSHLKYRKILEKMSDDELDALAEAL
HHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GESLDGIDLKKFVKRIITKKPSLLKYFKDLL
HCCCCCCCHHHHHHHHHCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087