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The map label for this gene is oppB

Identifier: 16273048

GI number: 16273048

Start: 1189308

End: 1190228

Strand: Reverse

Name: oppB

Synonym: HI1123

Alternate gene names: 16273048

Gene position: 1190228-1189308 (Counterclockwise)

Preceding gene: 16273049

Following gene: 16273047

Centisome position: 65.03

GC content: 41.59

Gene sequence:

>921_bases
ATGCTCAAGTTTATTTTTAAACGGCTGTTGGAAGCCTTACCGACGCTGTTTATTTTGATTACTTTTTCTTTCTTTTTGAT
GCGTCTCGCCCCTGGCAGCCCCTTCACTTCTGAACGCGCTTATCCGCCAGAAGTCATGGCTAATATCGAAGCGAAGTATC
ATTTAAATGAACCATTATATAAACAATATTTCCTTTATTTAGAAAATCTTTCCAAAGGAGATTTTGGTCCCTCTTTTAAA
TATAAAGACCAATCAGTCAATGATTTAATCGCGTCAGCTTTCCCTGTTTCCATAAAATTGGGAATGGTGGCCTTCGCCTT
TGCAGTCGTGCTAGGAGTAACAGCAGGTACGCTCGCCGCTCTCAATCAAAATAGCCGTTGGGATTATATTTTGATGAGTT
TCTCGATGCTTGGGGTCATTATGCCAAGCTTTGTCTTCGCACCTGTTTTAGTGCTAATTTTCGCCATTTATCTAGGATGG
CTGCCAGCTGGCGGTTGGAACGGCGGTACCGCCATGTACATGATCTTACCTGTAGCCTCCTTAACTATCGCTTATGTTGC
AGGGATTGCGCGTATCATGCGTGGTTCGATGATTGAAGTGTTACATTCCAACTTTATTCGAACCGCCAAAGCTAAAGGAC
TTTCCATGTCGAGAATCATTTTAAAACATGCTTTGCGCCCCGCACTTTTACCCGTGATAACCTATTTAGGACCTGCTTTC
GTAGGGATTATTACTGGCTCAATGGTCATCGAAAGCGTATTTGGTTTACCTGGCATGGGATTATTATTTGTAAACGGGGC
ATTGAACCGCGATTACTCTTTAGTTTTGAGCCTCACCATTTTAGTGGGGACATTAACCATTTTATTTAATGCGATTGTGG
ATATTTTATACGCCATCATCGATCCAAAAATTCGTTATTAA

Upstream 100 bases:

>100_bases
TTTATATTATTAAACATTAATTCGTTACTCGTATTTAAGTGCGGTTAAAAATCGTCGTATTTTTTGACCGCACTTTTCGC
CCATTTTGGTTGGAGTTGTT

Downstream 100 bases:

>100_bases
GGATAAATTATGACAGATTATCGTACTCAGCCGATTAATCAGAAAAATGCGGATTTTGTGGAACAAGTGGCTGACCGTAT
TGAAGAAATGCAACTGGAAG

Product: oligopeptide transporter permease

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLKFIFKRLLEALPTLFILITFSFFLMRLAPGSPFTSERAYPPEVMANIEAKYHLNEPLYKQYFLYLENLSKGDFGPSFK
YKDQSVNDLIASAFPVSIKLGMVAFAFAVVLGVTAGTLAALNQNSRWDYILMSFSMLGVIMPSFVFAPVLVLIFAIYLGW
LPAGGWNGGTAMYMILPVASLTIAYVAGIARIMRGSMIEVLHSNFIRTAKAKGLSMSRIILKHALRPALLPVITYLGPAF
VGIITGSMVIESVFGLPGMGLLFVNGALNRDYSLVLSLTILVGTLTILFNAIVDILYAIIDPKIRY

Sequences:

>Translated_306_residues
MLKFIFKRLLEALPTLFILITFSFFLMRLAPGSPFTSERAYPPEVMANIEAKYHLNEPLYKQYFLYLENLSKGDFGPSFK
YKDQSVNDLIASAFPVSIKLGMVAFAFAVVLGVTAGTLAALNQNSRWDYILMSFSMLGVIMPSFVFAPVLVLIFAIYLGW
LPAGGWNGGTAMYMILPVASLTIAYVAGIARIMRGSMIEVLHSNFIRTAKAKGLSMSRIILKHALRPALLPVITYLGPAF
VGIITGSMVIESVFGLPGMGLLFVNGALNRDYSLVLSLTILVGTLTILFNAIVDILYAIIDPKIRY
>Mature_306_residues
MLKFIFKRLLEALPTLFILITFSFFLMRLAPGSPFTSERAYPPEVMANIEAKYHLNEPLYKQYFLYLENLSKGDFGPSFK
YKDQSVNDLIASAFPVSIKLGMVAFAFAVVLGVTAGTLAALNQNSRWDYILMSFSMLGVIMPSFVFAPVLVLIFAIYLGW
LPAGGWNGGTAMYMILPVASLTIAYVAGIARIMRGSMIEVLHSNFIRTAKAKGLSMSRIILKHALRPALLPVITYLGPAF
VGIITGSMVIESVFGLPGMGLLFVNGALNRDYSLVLSLTILVGTLTILFNAIVDILYAIIDPKIRY

Specific function: Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787497, Length=306, Percent_Identity=75.4901960784314, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1787053, Length=309, Percent_Identity=37.5404530744337, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=31.3609467455621, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1789888, Length=310, Percent_Identity=32.5806451612903, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=28.1767955801105, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=30.7692307692308, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787761, Length=312, Percent_Identity=30.4487179487179, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OPPB_HAEIN (P45054)

Other databases:

- EMBL:   L42023
- PIR:   E64184
- RefSeq:   NP_439280.1
- GeneID:   950094
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1123
- TIGR:   HI_1123
- HOGENOM:   HBG724229
- OMA:   KYMILPM
- ProtClustDB:   PRK09471
- BioCyc:   HINF71421:HI_1123-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 33691; Mature: 33691

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc60ba5c)-; HASH(0xd9a42b0)-; HASH(0xe249dec)-; HASH(0xdb860f4)-; HASH(0xdd9db88)-; HASH(0xdfd9c14)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCH
>Mature Secondary Structure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CCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800