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The map label for this gene is mreD

Identifier: 16272014

GI number: 16272014

Start: 42335

End: 42823

Strand: Direct

Name: mreD

Synonym: HI0039

Alternate gene names: 16272014

Gene position: 42335-42823 (Clockwise)

Preceding gene: 16272013

Following gene: 30995350

Centisome position: 2.31

GC content: 34.97

Gene sequence:

>489_bases
ATGCAAACACGATTTATTTTACAATGGTTCACTATTTTAAGCTTCTTTGTTATTGCCTTTGTATTAGAACTTGCACCTTG
GCCAGTTGGTTTCCAAATGCTAAAGCCTGCGTGGCTTGTACTTGTATTACTTTATTGGGTATTAGCTATTCCCAATAAAG
TAAGTATAGGCTGGTCATTTTTACTCGGATTAACTTGGGATTTAATATTAGGCTCTACATTAGGCGTTCACGCTCTTGTA
CTTTCTACGAGCATGTACATCATTGCCAAAAACTATTTAATTCTGCGAAATTTATCACTTTGGTTCCAAAGTTTATTGGT
TGTACTTTTCGTCTTCATTATAAGATTACTTATTTTCTTAGTTGAATTTTCACTCCATACTGCCTTTTTTCATTGGCAAG
CCATCTTGGGCGCATTCGCTTCTGGTTTACTATGGCCGTGGGTATTTTTATTAATGCGCAAAATACGCAGAAAAGTTAAA
TTACATTAA

Upstream 100 bases:

>100_bases
ATGAAGAAAAAACCATTATTGAACCAGATATTCCAACAGATTTTCTTCAAAATGAAGAAGATCTTCCCATAGAACAGCAA
GAAGAAAGGATAGAAGACTA

Downstream 100 bases:

>100_bases
AAAAGAGAGATAACTCTCTCTTTTTTATGATTTATGAATGTTTCAAACACCTAATTCAATGGCTTATTGCTATCCAGTAA
AGAATCACATTCCCAACCGA

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MQTRFILQWFTILSFFVIAFVLELAPWPVGFQMLKPAWLVLVLLYWVLAIPNKVSIGWSFLLGLTWDLILGSTLGVHALV
LSTSMYIIAKNYLILRNLSLWFQSLLVVLFVFIIRLLIFLVEFSLHTAFFHWQAILGAFASGLLWPWVFLLMRKIRRKVK
LH

Sequences:

>Translated_162_residues
MQTRFILQWFTILSFFVIAFVLELAPWPVGFQMLKPAWLVLVLLYWVLAIPNKVSIGWSFLLGLTWDLILGSTLGVHALV
LSTSMYIIAKNYLILRNLSLWFQSLLVVLFVFIIRLLIFLVEFSLHTAFFHWQAILGAFASGLLWPWVFLLMRKIRRKVK
LH
>Mature_162_residues
MQTRFILQWFTILSFFVIAFVLELAPWPVGFQMLKPAWLVLVLLYWVLAIPNKVSIGWSFLLGLTWDLILGSTLGVHALV
LSTSMYIIAKNYLILRNLSLWFQSLLVVLFVFIIRLLIFLVEFSLHTAFFHWQAILGAFASGLLWPWVFLLMRKIRRKVK
LH

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family

Homologues:

Organism=Escherichia coli, GI1789647, Length=143, Percent_Identity=41.958041958042, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRED_HAEIN (P44476)

Other databases:

- EMBL:   L42023
- PIR:   G64044
- RefSeq:   NP_438212.1
- GeneID:   950936
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0039
- TIGR:   HI_0039
- HOGENOM:   HBG701138
- OMA:   YLVALNF
- ProtClustDB:   CLSK870680
- BioCyc:   HINF71421:HI_0039-MONOMER
- InterPro:   IPR007227
- TIGRFAMs:   TIGR03426

Pfam domain/function: PF04093 MreD

EC number: NA

Molecular weight: Translated: 18966; Mature: 18966

Theoretical pI: Translated: 11.37; Mature: 11.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbda75e4)-; HASH(0xb551120)-; HASH(0xbe592ec)-; HASH(0xb55ca04)-; HASH(0xb1a8570)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTRFILQWFTILSFFVIAFVLELAPWPVGFQMLKPAWLVLVLLYWVLAIPNKVSIGWSF
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLGLTWDLILGSTLGVHALVLSTSMYIIAKNYLILRNLSLWFQSLLVVLFVFIIRLLIFL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEFSLHTAFFHWQAILGAFASGLLWPWVFLLMRKIRRKVKLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MQTRFILQWFTILSFFVIAFVLELAPWPVGFQMLKPAWLVLVLLYWVLAIPNKVSIGWSF
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLGLTWDLILGSTLGVHALVLSTSMYIIAKNYLILRNLSLWFQSLLVVLFVFIIRLLIFL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEFSLHTAFFHWQAILGAFASGLLWPWVFLLMRKIRRKVKLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800