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The map label for this gene is mreC

Identifier: 16272013

GI number: 16272013

Start: 41280

End: 42335

Strand: Direct

Name: mreC

Synonym: HI0038

Alternate gene names: 16272013

Gene position: 41280-42335 (Clockwise)

Preceding gene: 30995349

Following gene: 16272014

Centisome position: 2.26

GC content: 37.5

Gene sequence:

>1056_bases
ATGAAACCCATTTTCGGCAAAGCCCCTCCCCTAGGTATTCGTCTGCTTATCGCTATCTTTGCATCTATTGCCTTAATTTT
AGCTGATGGACGTAATAGCTCAATAACGAAAGCACGTAGTGCAATGGAAACGGCAATAGGCGGTTTATATTATCTTGCAA
ATAGCCCTAGAAGTATCTTAGATGGCATTTCAGAAAATCTTGTTGATACCAATAAATTACAAATTGAAAACAAAGTACTA
CGCCAACAGCTTTTGGAAAAAAATGCAGATTTACTTTTACTTGATCAACTCAAAGTCGAAAATCAGCGATTACGTCTTTT
ATTAAATTCTCCGTTAAGAACCGATGAATACAAAAAAATTGCCGAAGTTCTTACTGCAGAAACAGATATTTATCGCCAAC
AAATTGTTATTAATCAAGGCAAAAAAGACGGTGCTTATGTAGGTCAGCCTGTCATTGATGAAAAAGGCGTCATTGGACAA
ATTATTTCCGTGGGCGAAAATACTAGCCGAGTACTGCTACTCACAGACGTAACACACTCAATTCCAGTGCAAGTTCTACG
CAATGATGTTCGTGTTATTGCGAGTGGGACTGGGCATACCGATGAACTAAGCCTCGATAACGTGCCTCGTTCCGTTGATA
TAGAAAAAGGCGATCTTCTCGTAACCTCTGGGCTTGGTGGACGTTTTCTTGAAGGCTATCCCGTAGCTGTTGTACAAAGC
GTTTCACGTGATAGCTCTAATTACTTTGCAATAGTTAAAGCTAAACCTTTAGCTTTATTAGAACGTTTACGTTATGTACT
TTTACTTTGGCCAAGTAACCTAGATATATCAAAAGTAAAATCAATATCGCCAGAAGAAGTTCGCAATCTGGTGCAAAAAC
GTTTAGAAAGCCAAGCTAATGAAGCAAATTATAGAGTGAAAAAAACACCCTTAACAGAAAAAGACTTTCTAGAAAATGAA
GAAAAAACCATTATTGAACCAGATATTCCAACAGATTTTCTTCAAAATGAAGAAGATCTTCCCATAGAACAGCAAGAAGA
AAGGATAGAAGACTAA

Upstream 100 bases:

>100_bases
ATTTTTAGTGATGAAATTTAATCAGAATATGAACAAAAAGTGCGGTTAAAAATAACCGCACTTTTCCTTTCACTTTTTTC
ATTCAACAAGAGAAAGTTTA

Downstream 100 bases:

>100_bases
TGCAAACACGATTTATTTTACAATGGTTCACTATTTTAAGCTTCTTTGTTATTGCCTTTGTATTAGAACTTGCACCTTGG
CCAGTTGGTTTCCAAATGCT

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKPIFGKAPPLGIRLLIAIFASIALILADGRNSSITKARSAMETAIGGLYYLANSPRSILDGISENLVDTNKLQIENKVL
RQQLLEKNADLLLLDQLKVENQRLRLLLNSPLRTDEYKKIAEVLTAETDIYRQQIVINQGKKDGAYVGQPVIDEKGVIGQ
IISVGENTSRVLLLTDVTHSIPVQVLRNDVRVIASGTGHTDELSLDNVPRSVDIEKGDLLVTSGLGGRFLEGYPVAVVQS
VSRDSSNYFAIVKAKPLALLERLRYVLLLWPSNLDISKVKSISPEEVRNLVQKRLESQANEANYRVKKTPLTEKDFLENE
EKTIIEPDIPTDFLQNEEDLPIEQQEERIED

Sequences:

>Translated_351_residues
MKPIFGKAPPLGIRLLIAIFASIALILADGRNSSITKARSAMETAIGGLYYLANSPRSILDGISENLVDTNKLQIENKVL
RQQLLEKNADLLLLDQLKVENQRLRLLLNSPLRTDEYKKIAEVLTAETDIYRQQIVINQGKKDGAYVGQPVIDEKGVIGQ
IISVGENTSRVLLLTDVTHSIPVQVLRNDVRVIASGTGHTDELSLDNVPRSVDIEKGDLLVTSGLGGRFLEGYPVAVVQS
VSRDSSNYFAIVKAKPLALLERLRYVLLLWPSNLDISKVKSISPEEVRNLVQKRLESQANEANYRVKKTPLTEKDFLENE
EKTIIEPDIPTDFLQNEEDLPIEQQEERIED
>Mature_351_residues
MKPIFGKAPPLGIRLLIAIFASIALILADGRNSSITKARSAMETAIGGLYYLANSPRSILDGISENLVDTNKLQIENKVL
RQQLLEKNADLLLLDQLKVENQRLRLLLNSPLRTDEYKKIAEVLTAETDIYRQQIVINQGKKDGAYVGQPVIDEKGVIGQ
IISVGENTSRVLLLTDVTHSIPVQVLRNDVRVIASGTGHTDELSLDNVPRSVDIEKGDLLVTSGLGGRFLEGYPVAVVQS
VSRDSSNYFAIVKAKPLALLERLRYVLLLWPSNLDISKVKSISPEEVRNLVQKRLESQANEANYRVKKTPLTEKDFLENE
EKTIIEPDIPTDFLQNEEDLPIEQQEERIED

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family

Homologues:

Organism=Escherichia coli, GI1789648, Length=295, Percent_Identity=50.1694915254237, Blast_Score=275, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MREC_HAEIN (P44475)

Other databases:

- EMBL:   L42023
- PIR:   F64044
- RefSeq:   NP_438211.1
- ProteinModelPortal:   P44475
- SMR:   P44475
- GeneID:   950932
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0038
- NMPDR:   fig|71421.1.peg.37
- TIGR:   HI_0038
- HOGENOM:   HBG751983
- OMA:   DGAYVGQ
- ProtClustDB:   PRK13922
- BioCyc:   HINF71421:HI_0038-MONOMER
- InterPro:   IPR007221
- InterPro:   IPR005223
- TIGRFAMs:   TIGR00219

Pfam domain/function: PF04085 MreC

EC number: NA

Molecular weight: Translated: 39184; Mature: 39184

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFGKAPPLGIRLLIAIFASIALILADGRNSSITKARSAMETAIGGLYYLANSPRSIL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHH
DGISENLVDTNKLQIENKVLRQQLLEKNADLLLLDQLKVENQRLRLLLNSPLRTDEYKKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHEECCCCCCHHHHHH
AEVLTAETDIYRQQIVINQGKKDGAYVGQPVIDEKGVIGQIISVGENTSRVLLLTDVTHS
HHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCH
IPVQVLRNDVRVIASGTGHTDELSLDNVPRSVDIEKGDLLVTSGLGGRFLEGYPVAVVQS
HHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHH
VSRDSSNYFAIVKAKPLALLERLRYVLLLWPSNLDISKVKSISPEEVRNLVQKRLESQAN
HCCCCCCEEEEEECCHHHHHHHHHEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCC
EANYRVKKTPLTEKDFLENEEKTIIEPDIPTDFLQNEEDLPIEQQEERIED
CCCEEEEECCCCHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKPIFGKAPPLGIRLLIAIFASIALILADGRNSSITKARSAMETAIGGLYYLANSPRSIL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHH
DGISENLVDTNKLQIENKVLRQQLLEKNADLLLLDQLKVENQRLRLLLNSPLRTDEYKKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHEECCCCCCHHHHHH
AEVLTAETDIYRQQIVINQGKKDGAYVGQPVIDEKGVIGQIISVGENTSRVLLLTDVTHS
HHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCH
IPVQVLRNDVRVIASGTGHTDELSLDNVPRSVDIEKGDLLVTSGLGGRFLEGYPVAVVQS
HHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHH
VSRDSSNYFAIVKAKPLALLERLRYVLLLWPSNLDISKVKSISPEEVRNLVQKRLESQAN
HCCCCCCEEEEEECCHHHHHHHHHEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCC
EANYRVKKTPLTEKDFLENEEKTIIEPDIPTDFLQNEEDLPIEQQEERIED
CCCEEEEECCCCHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800