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The map label for this gene is helB [H]

Identifier: 99080841

GI number: 99080841

Start: 1072044

End: 1072700

Strand: Direct

Name: helB [H]

Synonym: TM1040_1000

Alternate gene names: 99080841

Gene position: 1072044-1072700 (Clockwise)

Preceding gene: 99080840

Following gene: 99080842

Centisome position: 33.49

GC content: 64.23

Gene sequence:

>657_bases
GTGATTGCACTCTTGATGCGGGATCTGCGGCTGGCGTTGCGGGCCGGGGGAGGATTTGGGCTTGGGCTTGCGTTTTTCCT
GATCGTGACCGTGATGGTGCCTTTCTCGGTCGGCCCCGAGGCCGAGACATTGGCAAAGATTGCACCGGGCGTTTTATGGC
TCGGGGCCTTGCTGGCGTGTCTGTTGTCGCTCGATCGTCTTCTGGCGCTGGATTGGGAGGATGGCTCGCTGGACCTTTTG
GCCACGGCCCCGCTGCCGCTTGAAGGGGTCCTCAGCATCAAGGCACTGGCACATTGGTTGACCACGGGGCTGCCCCTGGT
GCTGGCAGCCCCCGTGCTGGGCGTCCTGCTCGGCCTTCCGGCGGGCGGCTATCTCTGGATCACGCTGTCGCTTTTGCTGG
GCACGCCGGCACTTTCGGTTGTGGGTACGTTTGGCGCGGCCCTGACCGTCGGGCTTAAGCGGGGCGGTTTGTTGTTGTCG
CTGCTGGTGATGCCGCTCTATGTGCCGACCCTGATCTTTGGCGCCGAAGTGGCGCGTCGGGGAGCGGCGGGGCTTGCGGT
AGAAACCCCCATGTTGATGCTTGGGGGGATCACCCTTGGCACCATCGCCCTGTTGCCCTTTGCCTCCGCTGCCGTCCTGC
GCGTCAATTTGCGCTAG

Upstream 100 bases:

>100_bases
CGACCCATATCGACCTTGGGATCGAGGGCAGGGTGCTGGACCTTGGTCCCTTTAAGGCCAAGCTTCCGGCGCTGGACGCC
GAGGATCTGGGGGGCTTCTT

Downstream 100 bases:

>100_bases
GACAGGTGATTGTGATGACCAAGAACAAGAGCTAGATAGCCACCATGTCGATCTGGGAATACGCCAATCCAAAGAAATTC
CTGCGCACCAGTGAGCGTGT

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein HelB [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIALLMRDLRLALRAGGGFGLGLAFFLIVTVMVPFSVGPEAETLAKIAPGVLWLGALLACLLSLDRLLALDWEDGSLDLL
ATAPLPLEGVLSIKALAHWLTTGLPLVLAAPVLGVLLGLPAGGYLWITLSLLLGTPALSVVGTFGAALTVGLKRGGLLLS
LLVMPLYVPTLIFGAEVARRGAAGLAVETPMLMLGGITLGTIALLPFASAAVLRVNLR

Sequences:

>Translated_218_residues
MIALLMRDLRLALRAGGGFGLGLAFFLIVTVMVPFSVGPEAETLAKIAPGVLWLGALLACLLSLDRLLALDWEDGSLDLL
ATAPLPLEGVLSIKALAHWLTTGLPLVLAAPVLGVLLGLPAGGYLWITLSLLLGTPALSVVGTFGAALTVGLKRGGLLLS
LLVMPLYVPTLIFGAEVARRGAAGLAVETPMLMLGGITLGTIALLPFASAAVLRVNLR
>Mature_218_residues
MIALLMRDLRLALRAGGGFGLGLAFFLIVTVMVPFSVGPEAETLAKIAPGVLWLGALLACLLSLDRLLALDWEDGSLDLL
ATAPLPLEGVLSIKALAHWLTTGLPLVLAAPVLGVLLGLPAGGYLWITLSLLLGTPALSVVGTFGAALTVGLKRGGLLLS
LLVMPLYVPTLIFGAEVARRGAAGLAVETPMLMLGGITLGTIALLPFASAAVLRVNLR

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=211, Percent_Identity=47.39336492891, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22417; Mature: 22417

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLMRDLRLALRAGGGFGLGLAFFLIVTVMVPFSVGPEAETLAKIAPGVLWLGALLAC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHH
LLSLDRLLALDWEDGSLDLLATAPLPLEGVLSIKALAHWLTTGLPLVLAAPVLGVLLGLP
HHHHHHHHEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AGGYLWITLSLLLGTPALSVVGTFGAALTVGLKRGGLLLSLLVMPLYVPTLIFGAEVARR
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
GAAGLAVETPMLMLGGITLGTIALLPFASAAVLRVNLR
CCCCCEECCHHHHHCCHHHHHHHHHHHCCEEEEEEECC
>Mature Secondary Structure
MIALLMRDLRLALRAGGGFGLGLAFFLIVTVMVPFSVGPEAETLAKIAPGVLWLGALLAC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHH
LLSLDRLLALDWEDGSLDLLATAPLPLEGVLSIKALAHWLTTGLPLVLAAPVLGVLLGLP
HHHHHHHHEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AGGYLWITLSLLLGTPALSVVGTFGAALTVGLKRGGLLLSLLVMPLYVPTLIFGAEVARR
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
GAAGLAVETPMLMLGGITLGTIALLPFASAAVLRVNLR
CCCCCEECCHHHHHCCHHHHHHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1310666 [H]