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The map label for this gene is des [H]

Identifier: 99080833

GI number: 99080833

Start: 1064391

End: 1065344

Strand: Direct

Name: des [H]

Synonym: TM1040_0992

Alternate gene names: 99080833

Gene position: 1064391-1065344 (Clockwise)

Preceding gene: 99080832

Following gene: 99080834

Centisome position: 33.25

GC content: 55.03

Gene sequence:

>954_bases
ATGGATCTGAGAGCCTACACACGCCAGTACACCAAAAAGGACAACCGGCTCGCCGCGTTGAACTACTTTGGAACCTTCGT
TGTCTATTTTACGAGCCTCTATCTGGCGATTACCTATTCAAATCTATGGTTTGTGATGTGGCCTGCGGGCATTGTTTTTG
CCTTCAGCGCCGTGCGGCTTTATGTGCTGCAGCACGACACCGGGCATCATTCTCTCTTTGAAACCCGGGCACAGAACGAA
TTCGCGGGGCATGTGCTCTCGCCTTTCACCTTCGCTCCCTTTGAGGTGATGAAGCAAAATCACAACCTGCATCACGCCAA
TGTGGGCAATCTCGAACACCGCGAAACCGGCGAGATCCATACGATGACGGTCGAGGAGTGGAACCGGGCGGGGTTCTTGG
AGCGGGTGCTCTACCGGCTCTATCGCAATCCATTTGTGCTGGTGCCCCTCGGTGCGGCGTTCACCTATTTTGTTCGCTAC
CGCTGGCCCAAAAACACGGTTGAATTCGGCGTTTTTCCGGTGCTCCTGCACAACATCGCCATCATCGCTCTGCTCTATGG
GCTCTATCTGCTGGCCGGGGCAGAGGGGCTTTGGATCTGGCTTGGGTTCTCTTTTCTGGGTGGTATGATCGGGGTGTTCC
TCGTCTATTTGCAGCATAATTTCGAGGATACCTATTGGGACCGGCGTCCCGATCTCGATCCGCGCGATGCGGCCTTGCAG
GGATCGTCCTGCCTGGATTTCGGGTGGTTTTTCGATTTTGCCGTGGCCAATATCACCCTGCACGACATCCACCATTATAA
CGCGCGCATCCCGTGTTATCGGCTGCGCCAGTGCCATCACAATATGCCCGAACATATGTCGCTGCGTCGGATCAAGTTTC
GCGAGGCGATCCGCGCGCTTGGTCTGAAGCTCTGGGATGAGAAGCAAAAACGTCTGGTACCTTTCCCGAGCTGA

Upstream 100 bases:

>100_bases
GGGACTTGTCTTAGACCGTATGCATATTAACTATATGGAAGTGATTTAATCGGACACCGCAGTCACGCGGGTGTCACAGA
GCGTATTTATGGGGTCAGAC

Downstream 100 bases:

>100_bases
GAAAAGGCCGCAAGGTTGCTGCGCACAATCCGTACGCATGAGAGGTTGGACAGATCGTCGAACCCGGTGCTACGCTCGCG
ATGTGATTGACTTCAGGCAG

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MDLRAYTRQYTKKDNRLAALNYFGTFVVYFTSLYLAITYSNLWFVMWPAGIVFAFSAVRLYVLQHDTGHHSLFETRAQNE
FAGHVLSPFTFAPFEVMKQNHNLHHANVGNLEHRETGEIHTMTVEEWNRAGFLERVLYRLYRNPFVLVPLGAAFTYFVRY
RWPKNTVEFGVFPVLLHNIAIIALLYGLYLLAGAEGLWIWLGFSFLGGMIGVFLVYLQHNFEDTYWDRRPDLDPRDAALQ
GSSCLDFGWFFDFAVANITLHDIHHYNARIPCYRLRQCHHNMPEHMSLRRIKFREAIRALGLKLWDEKQKRLVPFPS

Sequences:

>Translated_317_residues
MDLRAYTRQYTKKDNRLAALNYFGTFVVYFTSLYLAITYSNLWFVMWPAGIVFAFSAVRLYVLQHDTGHHSLFETRAQNE
FAGHVLSPFTFAPFEVMKQNHNLHHANVGNLEHRETGEIHTMTVEEWNRAGFLERVLYRLYRNPFVLVPLGAAFTYFVRY
RWPKNTVEFGVFPVLLHNIAIIALLYGLYLLAGAEGLWIWLGFSFLGGMIGVFLVYLQHNFEDTYWDRRPDLDPRDAALQ
GSSCLDFGWFFDFAVANITLHDIHHYNARIPCYRLRQCHHNMPEHMSLRRIKFREAIRALGLKLWDEKQKRLVPFPS
>Mature_317_residues
MDLRAYTRQYTKKDNRLAALNYFGTFVVYFTSLYLAITYSNLWFVMWPAGIVFAFSAVRLYVLQHDTGHHSLFETRAQNE
FAGHVLSPFTFAPFEVMKQNHNLHHANVGNLEHRETGEIHTMTVEEWNRAGFLERVLYRLYRNPFVLVPLGAAFTYFVRY
RWPKNTVEFGVFPVLLHNIAIIALLYGLYLLAGAEGLWIWLGFSFLGGMIGVFLVYLQHNFEDTYWDRRPDLDPRDAALQ
GSSCLDFGWFFDFAVANITLHDIHHYNARIPCYRLRQCHHNMPEHMSLRRIKFREAIRALGLKLWDEKQKRLVPFPS

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 37264; Mature: 37264

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRAYTRQYTKKDNRLAALNYFGTFVVYFTSLYLAITYSNLWFVMWPAGIVFAFSAVRL
CCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHEE
YVLQHDTGHHSLFETRAQNEFAGHVLSPFTFAPFEVMKQNHNLHHANVGNLEHRETGEIH
EEEECCCCCHHHHHHHHCCHHCCHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEE
TMTVEEWNRAGFLERVLYRLYRNPFVLVPLGAAFTYFVRYRWPKNTVEFGVFPVLLHNIA
EEEHHHHHCCHHHHHHHHHHHCCCEEEEECHHHHEEHHHEECCCCCHHHHHHHHHHHHHH
IIALLYGLYLLAGAEGLWIWLGFSFLGGMIGVFLVYLQHNFEDTYWDRRPDLDPRDAALQ
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCC
GSSCLDFGWFFDFAVANITLHDIHHYNARIPCYRLRQCHHNMPEHMSLRRIKFREAIRAL
CCCCCHHHHHHHHHHHHEEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GLKLWDEKQKRLVPFPS
CHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MDLRAYTRQYTKKDNRLAALNYFGTFVVYFTSLYLAITYSNLWFVMWPAGIVFAFSAVRL
CCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHEE
YVLQHDTGHHSLFETRAQNEFAGHVLSPFTFAPFEVMKQNHNLHHANVGNLEHRETGEIH
EEEECCCCCHHHHHHHHCCHHCCHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEE
TMTVEEWNRAGFLERVLYRLYRNPFVLVPLGAAFTYFVRYRWPKNTVEFGVFPVLLHNIA
EEEHHHHHCCHHHHHHHHHHHCCCEEEEECHHHHEEHHHEECCCCCHHHHHHHHHHHHHH
IIALLYGLYLLAGAEGLWIWLGFSFLGGMIGVFLVYLQHNFEDTYWDRRPDLDPRDAALQ
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCC
GSSCLDFGWFFDFAVANITLHDIHHYNARIPCYRLRQCHHNMPEHMSLRRIKFREAIRAL
CCCCCHHHHHHHHHHHHEEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GLKLWDEKQKRLVPFPS
CHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]