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The map label for this gene is gbh [H]

Identifier: 99080780

GI number: 99080780

Start: 1002122

End: 1003069

Strand: Direct

Name: gbh [H]

Synonym: TM1040_0939

Alternate gene names: 99080780

Gene position: 1002122-1003069 (Clockwise)

Preceding gene: 99080779

Following gene: 99080782

Centisome position: 31.31

GC content: 60.76

Gene sequence:

>948_bases
ATGAGCGAGTTCAATCAACCCATCAGCGGCAATGATCTGGCGCGGTTCTCGGGGCCGGGCACCTTTATGCGCCTGCCGCA
GGCCACCTCGCTAGAGGGTCTGGATGTGGCGGTGCTGGGTGTGCCGATGGATATTGGCACCTCCTGGCGTTCCGGGACGC
GGTTCGGGCCCAAGCAGATCCGCGCCGAGAGCGCGATGATCCGCCCGTACAACATGGCCACCGGGGCTGCGCCTTTTGAT
GCGCTCAACATTGCCGATATTGGCGATCTGGCGATCAATACGTTCAACCTCGCGGAGTCGCTGCGCATCATCGAAGACAG
CTATGACGCGATCCTCGGTTCGGGCGTGCTTCCCTTTGCGATGGGGGGCGATCACTCGATCACCCTGCCGATCCTCAGGG
CGATGGCGCGCAGGTATGGCCCGGTTGCGGTGATCCATGTGGATGCCCATGCGGACGTCAATGACGAGATGTTTGGCGAG
CGCGAAACCCACGGCACCGTGTTCCGCCGCGCCTATGAAGAGGGGCTTCTGGAGGCGGATAAAGTTTATCAGATTGGTCT
GCGCGGTACCGGCTATGGACCGGATGATTTCAAAGAGCCGCAGAGCTGGGGCTTTCAGCATTTTGTCGCCTCCGAGCTCT
GGAACCGATCGCTGCACAATATGGGGGCGGAAATCCGTCGCGATATTGGCGGGCGTCCGGTCTATATCTCCTATGATATC
GACAGTCTTGATCCCGCCTTCGCGCCGGGCACCGGCACGCCGGAAATTGGCGGGCTGACCACCATGCAGGCGCTGGAGCT
GATCCGCGCCTTCAAGGGGCTCAATGTCGTGGGATGTGATCTTGTCGAAGTCTCGCCGCCCTACGACCCTTCGGGGAATA
CGGCGCTTGTAGCAGCCAATCTGATCTATGAGATGCTGTGCATCCTGCCAGGACGGGATAGGGCGTAA

Upstream 100 bases:

>100_bases
AAGTCTCGCCCCCCTTTGACACCACCGGCGCCACCGCCATCGCGGGCGCCCATGTGGCCATGAGTATTATCTGCCTTCTG
GGCTGGAGGATGACAGGACG

Downstream 100 bases:

>100_bases
CGCGCCAGAGGTCGCGCGTATCATCACCGCTGGATGAGCCGGGACTAGGTGCGCCGGGCGGGGAGGCTCCCGCCTGTTGC
TGGATCAGCAGAGCCGATCG

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSEFNQPISGNDLARFSGPGTFMRLPQATSLEGLDVAVLGVPMDIGTSWRSGTRFGPKQIRAESAMIRPYNMATGAAPFD
ALNIADIGDLAINTFNLAESLRIIEDSYDAILGSGVLPFAMGGDHSITLPILRAMARRYGPVAVIHVDAHADVNDEMFGE
RETHGTVFRRAYEEGLLEADKVYQIGLRGTGYGPDDFKEPQSWGFQHFVASELWNRSLHNMGAEIRRDIGGRPVYISYDI
DSLDPAFAPGTGTPEIGGLTTMQALELIRAFKGLNVVGCDLVEVSPPYDPSGNTALVAANLIYEMLCILPGRDRA

Sequences:

>Translated_315_residues
MSEFNQPISGNDLARFSGPGTFMRLPQATSLEGLDVAVLGVPMDIGTSWRSGTRFGPKQIRAESAMIRPYNMATGAAPFD
ALNIADIGDLAINTFNLAESLRIIEDSYDAILGSGVLPFAMGGDHSITLPILRAMARRYGPVAVIHVDAHADVNDEMFGE
RETHGTVFRRAYEEGLLEADKVYQIGLRGTGYGPDDFKEPQSWGFQHFVASELWNRSLHNMGAEIRRDIGGRPVYISYDI
DSLDPAFAPGTGTPEIGGLTTMQALELIRAFKGLNVVGCDLVEVSPPYDPSGNTALVAANLIYEMLCILPGRDRA
>Mature_314_residues
SEFNQPISGNDLARFSGPGTFMRLPQATSLEGLDVAVLGVPMDIGTSWRSGTRFGPKQIRAESAMIRPYNMATGAAPFDA
LNIADIGDLAINTFNLAESLRIIEDSYDAILGSGVLPFAMGGDHSITLPILRAMARRYGPVAVIHVDAHADVNDEMFGER
ETHGTVFRRAYEEGLLEADKVYQIGLRGTGYGPDDFKEPQSWGFQHFVASELWNRSLHNMGAEIRRDIGGRPVYISYDID
SLDPAFAPGTGTPEIGGLTTMQALELIRAFKGLNVVGCDLVEVSPPYDPSGNTALVAANLIYEMLCILPGRDRA

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=306, Percent_Identity=55.2287581699346, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI4502215, Length=310, Percent_Identity=25.4838709677419, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI10947139, Length=278, Percent_Identity=25.1798561151079, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1789306, Length=299, Percent_Identity=39.7993311036789, Blast_Score=185, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6325146, Length=210, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 34169; Mature: 34038

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFNQPISGNDLARFSGPGTFMRLPQATSLEGLDVAVLGVPMDIGTSWRSGTRFGPKQI
CCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
RAESAMIRPYNMATGAAPFDALNIADIGDLAINTFNLAESLRIIEDSYDAILGSGVLPFA
HHHHHEECCCCCCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCCCEEE
MGGDHSITLPILRAMARRYGPVAVIHVDAHADVNDEMFGERETHGTVFRRAYEEGLLEAD
ECCCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCC
KVYQIGLRGTGYGPDDFKEPQSWGFQHFVASELWNRSLHNMGAEIRRDIGGRPVYISYDI
CEEEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
DSLDPAFAPGTGTPEIGGLTTMQALELIRAFKGLNVVGCDLVEVSPPYDPSGNTALVAAN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECEEEECCCCCCCCCCEEEHHHH
LIYEMLCILPGRDRA
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEFNQPISGNDLARFSGPGTFMRLPQATSLEGLDVAVLGVPMDIGTSWRSGTRFGPKQI
CCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
RAESAMIRPYNMATGAAPFDALNIADIGDLAINTFNLAESLRIIEDSYDAILGSGVLPFA
HHHHHEECCCCCCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCCCEEE
MGGDHSITLPILRAMARRYGPVAVIHVDAHADVNDEMFGERETHGTVFRRAYEEGLLEAD
ECCCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCC
KVYQIGLRGTGYGPDDFKEPQSWGFQHFVASELWNRSLHNMGAEIRRDIGGRPVYISYDI
CEEEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
DSLDPAFAPGTGTPEIGGLTTMQALELIRAFKGLNVVGCDLVEVSPPYDPSGNTALVAAN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECEEEECCCCCCCCCCEEEHHHH
LIYEMLCILPGRDRA
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA