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The map label for this gene is speB [H]

Identifier: 99080779

GI number: 99080779

Start: 1001097

End: 1002125

Strand: Direct

Name: speB [H]

Synonym: TM1040_0938

Alternate gene names: 99080779

Gene position: 1001097-1002125 (Clockwise)

Preceding gene: 99080778

Following gene: 99080780

Centisome position: 31.28

GC content: 61.32

Gene sequence:

>1029_bases
ATGACAAGCCCGCCTGCATTGGCTAGGACGTCAGCAGAACCCGAGAACAGGGAGCAGTCCAAAATGGCGCTGGAAGACGC
AAAAACGCAGGTAGATCAGGCATTTACGCGCGAGGACCTTAAGGGTCTCAGCTTTGAGAACACCTTTGGAGGGGCCACGT
CGTTTCTGCGGCGTCGCTACACCAAGGATCTGACCCACGCGGATATCGCCGTGACGGGTATTCCGTTTGATCAGGCGGTG
ACAAACCGCCCCGGCACACGGCTGGGTCCGCGCGCGGTGCGCGAGGCCTCGGCCCTGCAAAGCCCCGATGCGCCTTATGG
CTGGGATATTTGCCCTGCAAGCGAGCTGGCAATCGTGGACTACGGCGATCTGGCCTTTGACTATGCCAATGTCCCGGCGT
TTCCCGACACGCTCACGGATCATATCCGGGGCATTCTGGCCACCGATACAGCATCGGTGGCGATTGGCGGCGACCATTAT
GTGAGCTTCCCGATCCTCAAGGCCTATGCCGAGAAATACGGGCCTGTTTCGCTCTTGCATTTCGATGCTCACAGCGACAC
CTGGGCGGATGATGATTTCAGCCGCGTGGATCATGGCACGATGTTCTACAAAGCGGTGAAATCCGGCATCATTGACCCGG
CTACCTCGGTGCAGGTGGGCATTCGCACCACCAATGAGGACAATCTGGGCGTGCCGACTATCGATGCCCCCACGGTGCAT
GAGATCGGCCCGGTCGAGACCGCGCGCCGCATCCGCGAGGTGCTGGGCGACCGGCCAGTCTATCTGACCTTTGACATTGA
CTGCCTCGATCCGGCCTATGCGCCGGGCACTGGCACCCCGGTCTGGGGTGGCCTCACCTCTGCGCAGGCAGAGGCGATCC
TCAAGGGGTTGCGCGGCATCAACATTCTGGGCGGCGACGTCGTCGAAGTCTCGCCCCCCTTTGACACCACCGGCGCCACC
GCCATCGCGGGCGCCCATGTGGCCATGAGTATTATCTGCCTTCTGGGCTGGAGGATGACAGGACGATGA

Upstream 100 bases:

>100_bases
TCAACGACGAGATCTCGCCTATTGGGGCATCGTTCTTTGCCCGTCTGGTGGAGAAAGCACAGCCAGCGGGTTGAAATCGC
GATGTGGGGCGGGCTTTCGG

Downstream 100 bases:

>100_bases
GCGAGTTCAATCAACCCATCAGCGGCAATGATCTGGCGCGGTTCTCGGGGCCGGGCACCTTTATGCGCCTGCCGCAGGCC
ACCTCGCTAGAGGGTCTGGA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTSPPALARTSAEPENREQSKMALEDAKTQVDQAFTREDLKGLSFENTFGGATSFLRRRYTKDLTHADIAVTGIPFDQAV
TNRPGTRLGPRAVREASALQSPDAPYGWDICPASELAIVDYGDLAFDYANVPAFPDTLTDHIRGILATDTASVAIGGDHY
VSFPILKAYAEKYGPVSLLHFDAHSDTWADDDFSRVDHGTMFYKAVKSGIIDPATSVQVGIRTTNEDNLGVPTIDAPTVH
EIGPVETARRIREVLGDRPVYLTFDIDCLDPAYAPGTGTPVWGGLTSAQAEAILKGLRGINILGGDVVEVSPPFDTTGAT
AIAGAHVAMSIICLLGWRMTGR

Sequences:

>Translated_342_residues
MTSPPALARTSAEPENREQSKMALEDAKTQVDQAFTREDLKGLSFENTFGGATSFLRRRYTKDLTHADIAVTGIPFDQAV
TNRPGTRLGPRAVREASALQSPDAPYGWDICPASELAIVDYGDLAFDYANVPAFPDTLTDHIRGILATDTASVAIGGDHY
VSFPILKAYAEKYGPVSLLHFDAHSDTWADDDFSRVDHGTMFYKAVKSGIIDPATSVQVGIRTTNEDNLGVPTIDAPTVH
EIGPVETARRIREVLGDRPVYLTFDIDCLDPAYAPGTGTPVWGGLTSAQAEAILKGLRGINILGGDVVEVSPPFDTTGAT
AIAGAHVAMSIICLLGWRMTGR
>Mature_341_residues
TSPPALARTSAEPENREQSKMALEDAKTQVDQAFTREDLKGLSFENTFGGATSFLRRRYTKDLTHADIAVTGIPFDQAVT
NRPGTRLGPRAVREASALQSPDAPYGWDICPASELAIVDYGDLAFDYANVPAFPDTLTDHIRGILATDTASVAIGGDHYV
SFPILKAYAEKYGPVSLLHFDAHSDTWADDDFSRVDHGTMFYKAVKSGIIDPATSVQVGIRTTNEDNLGVPTIDAPTVHE
IGPVETARRIREVLGDRPVYLTFDIDCLDPAYAPGTGTPVWGGLTSAQAEAILKGLRGINILGGDVVEVSPPFDTTGATA
IAGAHVAMSIICLLGWRMTGR

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=293, Percent_Identity=36.518771331058, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI10947139, Length=307, Percent_Identity=26.0586319218241, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789306, Length=280, Percent_Identity=42.5, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 36708; Mature: 36577

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPPALARTSAEPENREQSKMALEDAKTQVDQAFTREDLKGLSFENTFGGATSFLRRRY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
TKDLTHADIAVTGIPFDQAVTNRPGTRLGPRAVREASALQSPDAPYGWDICPASELAIVD
HHCCCCCCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
YGDLAFDYANVPAFPDTLTDHIRGILATDTASVAIGGDHYVSFPILKAYAEKYGPVSLLH
CCCHHEECCCCCCCCHHHHHHHHEEEEECCCEEEECCCCEEHHHHHHHHHHHCCCEEEEE
FDAHSDTWADDDFSRVDHGTMFYKAVKSGIIDPATSVQVGIRTTNEDNLGVPTIDAPTVH
EECCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
EIGPVETARRIREVLGDRPVYLTFDIDCLDPAYAPGTGTPVWGGLTSAQAEAILKGLRGI
CCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
NILGGDVVEVSPPFDTTGATAIAGAHVAMSIICLLGWRMTGR
EEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSPPALARTSAEPENREQSKMALEDAKTQVDQAFTREDLKGLSFENTFGGATSFLRRRY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
TKDLTHADIAVTGIPFDQAVTNRPGTRLGPRAVREASALQSPDAPYGWDICPASELAIVD
HHCCCCCCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
YGDLAFDYANVPAFPDTLTDHIRGILATDTASVAIGGDHYVSFPILKAYAEKYGPVSLLH
CCCHHEECCCCCCCCHHHHHHHHEEEEECCCEEEECCCCEEHHHHHHHHHHHCCCEEEEE
FDAHSDTWADDDFSRVDHGTMFYKAVKSGIIDPATSVQVGIRTTNEDNLGVPTIDAPTVH
EECCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
EIGPVETARRIREVLGDRPVYLTFDIDCLDPAYAPGTGTPVWGGLTSAQAEAILKGLRGI
CCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
NILGGDVVEVSPPFDTTGATAIAGAHVAMSIICLLGWRMTGR
EEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]