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The map label for this gene is hipO [H]

Identifier: 99080778

GI number: 99080778

Start: 999907

End: 1001070

Strand: Direct

Name: hipO [H]

Synonym: TM1040_0937

Alternate gene names: 99080778

Gene position: 999907-1001070 (Clockwise)

Preceding gene: 99080776

Following gene: 99080779

Centisome position: 31.24

GC content: 60.31

Gene sequence:

>1164_bases
ATGCCGGTCGTGAACCGCATCGCTGATTTTGCCGAAGACATGAAGACCTGGCGTCGCCACCTGCACCAGATCCCCGAACT
GGGGTTGGACACAGTAAAAACCGCTGCATATGTGACTGAGATCCTTGAGACATTCGGCGTAGATGAGATCCACGGCGGTA
TTGCGCAGAACGGGATCGTGGCGATCATCAACGGTCAGGGCGAAGGGCCAACACTTGGGCTTCGCGCCGATATGGACGCG
CTGCCGATCACCGAGGTGCGCGACCTCGACTACAAATCCCAGACCCCCGGCAAAATGCATGCCTGCGGCCATGACGGGCA
CACCACCATGTTGCTCGGGGCGGCGAAATATCTGGCGGAAACGCGTAATTTCAAAGGCCGCGTGGCGCTGTTGTTCCAGC
CCGCCGAAGAGATCATCGGCGGCGCCAAGATCATGGTCGAAGAGGGCGTGATGGAGCGCTTTGACATCAAGGAGGTCTAC
GCGCTGCACAATGCGCCGGGCTTGCCGGTCGGGCATTTCATGACAACGCCGGGCGCTTTGATGGCGGCGGTGGATGAGTT
TACCATCAACATCAAAGGGCTGGGTGGCCATGGCGCAATGCCGCATGAAACCCGTGATCCGGTGATGGCCGCCTGTGGCA
TGGCGCAAGCGATCCAGACCATCGTCAGCCGCAACCATCAGGCCACCGAAGATCTGGTGATCTCCGTCACCCAGATCCAC
ACTGGTACCGTCGACAATGTGATCCCCGAGACCGCCTATGTGAATGGCACCATCCGCACCTTCAATCCCGAGGTGCAAAA
GATGGTCATGGCGCGCTTTGACGAGATCGTGAAAGGCTGCGCCGTGGCCTATGGGGTGGAAGCGGAGCTGGATTACGAGG
TCGGCTATCCCGCCACGATCAACGACGCGGAAAAGGCGGCTTTTGCCACCGATATCGCGCGCGACATCTCGGGCGAGGCC
AATGTGCAGGGCGATGCGGGGCGCGAGATGGGGGCTGAGGATTTCTCTTATATGCTGGAGGCCCGTCCGGGCGCCTACCT
GTTCCTCGGGCAGGGGGATACGGCGGGGCTGCACCACCCTGAGTATGACTTCAACGACGAGATCTCGCCTATTGGGGCAT
CGTTCTTTGCCCGTCTGGTGGAGAAAGCACAGCCAGCGGGTTGA

Upstream 100 bases:

>100_bases
CCTGCGGTTTCATCGTGGATCAAGCTGTCGTCGCTCATTGCACCTGCCTGCGTTTTCGTGTCTGCTGCATCATCCCGACT
ATTTGACAGGAGTCCACCCC

Downstream 100 bases:

>100_bases
AATCGCGATGTGGGGCGGGCTTTCGGATGACAAGCCCGCCTGCATTGGCTAGGACGTCAGCAGAACCCGAGAACAGGGAG
CAGTCCAAAATGGCGCTGGA

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPVVNRIADFAEDMKTWRRHLHQIPELGLDTVKTAAYVTEILETFGVDEIHGGIAQNGIVAIINGQGEGPTLGLRADMDA
LPITEVRDLDYKSQTPGKMHACGHDGHTTMLLGAAKYLAETRNFKGRVALLFQPAEEIIGGAKIMVEEGVMERFDIKEVY
ALHNAPGLPVGHFMTTPGALMAAVDEFTINIKGLGGHGAMPHETRDPVMAACGMAQAIQTIVSRNHQATEDLVISVTQIH
TGTVDNVIPETAYVNGTIRTFNPEVQKMVMARFDEIVKGCAVAYGVEAELDYEVGYPATINDAEKAAFATDIARDISGEA
NVQGDAGREMGAEDFSYMLEARPGAYLFLGQGDTAGLHHPEYDFNDEISPIGASFFARLVEKAQPAG

Sequences:

>Translated_387_residues
MPVVNRIADFAEDMKTWRRHLHQIPELGLDTVKTAAYVTEILETFGVDEIHGGIAQNGIVAIINGQGEGPTLGLRADMDA
LPITEVRDLDYKSQTPGKMHACGHDGHTTMLLGAAKYLAETRNFKGRVALLFQPAEEIIGGAKIMVEEGVMERFDIKEVY
ALHNAPGLPVGHFMTTPGALMAAVDEFTINIKGLGGHGAMPHETRDPVMAACGMAQAIQTIVSRNHQATEDLVISVTQIH
TGTVDNVIPETAYVNGTIRTFNPEVQKMVMARFDEIVKGCAVAYGVEAELDYEVGYPATINDAEKAAFATDIARDISGEA
NVQGDAGREMGAEDFSYMLEARPGAYLFLGQGDTAGLHHPEYDFNDEISPIGASFFARLVEKAQPAG
>Mature_386_residues
PVVNRIADFAEDMKTWRRHLHQIPELGLDTVKTAAYVTEILETFGVDEIHGGIAQNGIVAIINGQGEGPTLGLRADMDAL
PITEVRDLDYKSQTPGKMHACGHDGHTTMLLGAAKYLAETRNFKGRVALLFQPAEEIIGGAKIMVEEGVMERFDIKEVYA
LHNAPGLPVGHFMTTPGALMAAVDEFTINIKGLGGHGAMPHETRDPVMAACGMAQAIQTIVSRNHQATEDLVISVTQIHT
GTVDNVIPETAYVNGTIRTFNPEVQKMVMARFDEIVKGCAVAYGVEAELDYEVGYPATINDAEKAAFATDIARDISGEAN
VQGDAGREMGAEDFSYMLEARPGAYLFLGQGDTAGLHHPEYDFNDEISPIGASFFARLVEKAQPAG

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=432, Percent_Identity=27.3148148148148, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41771; Mature: 41640

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVVNRIADFAEDMKTWRRHLHQIPELGLDTVKTAAYVTEILETFGVDEIHGGIAQNGIV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEE
AIINGQGEGPTLGLRADMDALPITEVRDLDYKSQTPGKMHACGHDGHTTMLLGAAKYLAE
EEEECCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
TRNFKGRVALLFQPAEEIIGGAKIMVEEGVMERFDIKEVYALHNAPGLPVGHFMTTPGAL
HCCCCCEEEEEEECHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHH
MAAVDEFTINIKGLGGHGAMPHETRDPVMAACGMAQAIQTIVSRNHQATEDLVISVTQIH
HHHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEHCC
TGTVDNVIPETAYVNGTIRTFNPEVQKMVMARFDEIVKGCAVAYGVEAELDYEVGYPATI
CCCHHHHCCCCEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
NDAEKAAFATDIARDISGEANVQGDAGREMGAEDFSYMLEARPGAYLFLGQGDTAGLHHP
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCC
EYDFNDEISPIGASFFARLVEKAQPAG
CCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PVVNRIADFAEDMKTWRRHLHQIPELGLDTVKTAAYVTEILETFGVDEIHGGIAQNGIV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEE
AIINGQGEGPTLGLRADMDALPITEVRDLDYKSQTPGKMHACGHDGHTTMLLGAAKYLAE
EEEECCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
TRNFKGRVALLFQPAEEIIGGAKIMVEEGVMERFDIKEVYALHNAPGLPVGHFMTTPGAL
HCCCCCEEEEEEECHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHH
MAAVDEFTINIKGLGGHGAMPHETRDPVMAACGMAQAIQTIVSRNHQATEDLVISVTQIH
HHHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEHCC
TGTVDNVIPETAYVNGTIRTFNPEVQKMVMARFDEIVKGCAVAYGVEAELDYEVGYPATI
CCCHHHHCCCCEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
NDAEKAAFATDIARDISGEANVQGDAGREMGAEDFSYMLEARPGAYLFLGQGDTAGLHHP
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCC
EYDFNDEISPIGASFFARLVEKAQPAG
CCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]