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The map label for this gene is 99080711

Identifier: 99080711

GI number: 99080711

Start: 927480

End: 928859

Strand: Direct

Name: 99080711

Synonym: TM1040_0870

Alternate gene names: NA

Gene position: 927480-928859 (Clockwise)

Preceding gene: 99080709

Following gene: 99080712

Centisome position: 28.98

GC content: 65.36

Gene sequence:

>1380_bases
ATGCTTTGCGACAGAACGGCCAGCGACATTCTAAAAGACCTCGCCAGAGGCGCGCTCACGGTCGAGGCCCTGATGCAGGC
AACGCTCGACCGCATTGGCGAACGCAACCCGGCGCTGAACGCGATTGTTGCCCTTCGCCCGACCGAGGATCTGATGGCAG
AGGCCCGCGCCGCGGATGCGGTGCCACGGGCCGAACGCGGCCCGCTCCATGGTCTGCCAATGGCAATCAAGGATCTCTCG
AATGCCAAGGGGCTGGTGACATCCCAAGGCTCGCCGATTTTTGCAGGGCAGGTGGCACAAGAGGACGATATCTTTGTGGC
GCGGTTGCGGGCGGCAGGGGTGATCGTGATTGGCAAGACAAATACGCCCGAGTTCGGGCTTGGGTCTCACACCTATAATC
CTGTCTATGGCGCCACCGGCAATGTGGTGGACCCCAGCCGCTCTGCGGGCGGATCGTCAGGAGGCGCTGCGGTGGCGCTG
GCGGCGGGAATGGTGGCGCTCGCGGATGGCTCTGACATGATGGGCTCACTGCGCAACCCGGCCGGATGGAACGAGATCTA
CGGCTTTCGTCCCACCTGGGGCTGGATCCCTTCCGAGCCCGTGGGCGATGTGTTCCTGCACCCGCTCTCAACCAGTGGAC
CGATGGCGCGCACGCCAGAGGATCTGGCGCTTCTTCTGGATGTGATGTCCGGCAGTGATCCGCGTTTGCCGCTCGCGCGC
GGTGCAGAAACGGTCTCTCCGCTGAAGGCCCCAAAGCCACTGCGGCTGGGCTGGCTTGGCGATTGGGGCGGGGCTTACCC
AATGGACGACGGCCTCCTTGAGACCTGTGATGCGGCGCTTCAGACCTTTGTGGAGCAGGGCCACACGGTAGAGCGGATCG
CGCCGCCATATCCTGCAGAGAAGATCTGGCAGAGCTGGATCACCCTGCGCTCCTTTGCGGTGGCGGCGGGGCTTCGCGGG
TTGAACAACCGGCGCGCGGATCTGAAAGAGGCAGCGCTCTGGGAGTTGGACCGTGGGCTAGGGTTCAGCGCGCAAGAGGT
GCAGGAAGCCTCCGATCTGCGCTCGGGCTGGATGCGCGCGGCTGCACGGATGTTTCAGCGCTATGACGCGGTGGTGTTGC
CCACTGCGCAATGCTGGCCGTTTCCGATCGACTGGGACTACCCAAAGGAGATCGCCGGCAAACCCCTGGACACCTACCAC
CGCTGGATGGAGGTGGTGGTGCCCGCAAGCCTGTTGGGACTGCCTGCCTTGGCGGTGCCTGCCGGGCGGGGCGGGGCGGA
CCACTTGCCCATCGGGCTGCAGATCATCGGCCCGCACGGCAGCGACGGGCAGATCCTCGGGCTTGGGCAGGGATATCACA
CCGCGCGCGCCGCGCTCTAG

Upstream 100 bases:

>100_bases
CCTTGATGCGCATGAAAAAGGTGCGGAATTTTAGGGTCTTTTCAGACCGTTATCCGCAGCCTAGGCTGACCGGCAATAAG
ACCCAGAGGAACTTCAGATC

Downstream 100 bases:

>100_bases
CTCCGGCACCCGATCAGATCGCATGTGCATTGCATAGGGAGGCTCTGCAAGACGATGACGCAAACCACAGAAACACCGAC
CGCGCCTCTTACGCGACCGC

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLCDRTASDILKDLARGALTVEALMQATLDRIGERNPALNAIVALRPTEDLMAEARAADAVPRAERGPLHGLPMAIKDLS
NAKGLVTSQGSPIFAGQVAQEDDIFVARLRAAGVIVIGKTNTPEFGLGSHTYNPVYGATGNVVDPSRSAGGSSGGAAVAL
AAGMVALADGSDMMGSLRNPAGWNEIYGFRPTWGWIPSEPVGDVFLHPLSTSGPMARTPEDLALLLDVMSGSDPRLPLAR
GAETVSPLKAPKPLRLGWLGDWGGAYPMDDGLLETCDAALQTFVEQGHTVERIAPPYPAEKIWQSWITLRSFAVAAGLRG
LNNRRADLKEAALWELDRGLGFSAQEVQEASDLRSGWMRAAARMFQRYDAVVLPTAQCWPFPIDWDYPKEIAGKPLDTYH
RWMEVVVPASLLGLPALAVPAGRGGADHLPIGLQIIGPHGSDGQILGLGQGYHTARAAL

Sequences:

>Translated_459_residues
MLCDRTASDILKDLARGALTVEALMQATLDRIGERNPALNAIVALRPTEDLMAEARAADAVPRAERGPLHGLPMAIKDLS
NAKGLVTSQGSPIFAGQVAQEDDIFVARLRAAGVIVIGKTNTPEFGLGSHTYNPVYGATGNVVDPSRSAGGSSGGAAVAL
AAGMVALADGSDMMGSLRNPAGWNEIYGFRPTWGWIPSEPVGDVFLHPLSTSGPMARTPEDLALLLDVMSGSDPRLPLAR
GAETVSPLKAPKPLRLGWLGDWGGAYPMDDGLLETCDAALQTFVEQGHTVERIAPPYPAEKIWQSWITLRSFAVAAGLRG
LNNRRADLKEAALWELDRGLGFSAQEVQEASDLRSGWMRAAARMFQRYDAVVLPTAQCWPFPIDWDYPKEIAGKPLDTYH
RWMEVVVPASLLGLPALAVPAGRGGADHLPIGLQIIGPHGSDGQILGLGQGYHTARAAL
>Mature_459_residues
MLCDRTASDILKDLARGALTVEALMQATLDRIGERNPALNAIVALRPTEDLMAEARAADAVPRAERGPLHGLPMAIKDLS
NAKGLVTSQGSPIFAGQVAQEDDIFVARLRAAGVIVIGKTNTPEFGLGSHTYNPVYGATGNVVDPSRSAGGSSGGAAVAL
AAGMVALADGSDMMGSLRNPAGWNEIYGFRPTWGWIPSEPVGDVFLHPLSTSGPMARTPEDLALLLDVMSGSDPRLPLAR
GAETVSPLKAPKPLRLGWLGDWGGAYPMDDGLLETCDAALQTFVEQGHTVERIAPPYPAEKIWQSWITLRSFAVAAGLRG
LNNRRADLKEAALWELDRGLGFSAQEVQEASDLRSGWMRAAARMFQRYDAVVLPTAQCWPFPIDWDYPKEIAGKPLDTYH
RWMEVVVPASLLGLPALAVPAGRGGADHLPIGLQIIGPHGSDGQILGLGQGYHTARAAL

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=469, Percent_Identity=30.0639658848614, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI222831590, Length=518, Percent_Identity=24.5173745173745, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17537465, Length=494, Percent_Identity=23.8866396761134, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17538252, Length=349, Percent_Identity=26.9340974212034, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17543272, Length=203, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556264, Length=242, Percent_Identity=30.5785123966942, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538254, Length=275, Percent_Identity=28.3636363636364, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71990152, Length=227, Percent_Identity=30.8370044052863, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323950, Length=467, Percent_Identity=23.3404710920771, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319685, Length=430, Percent_Identity=26.5116279069767, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320448, Length=168, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550774, Length=258, Percent_Identity=35.2713178294574, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24648435, Length=258, Percent_Identity=35.2713178294574, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24648437, Length=258, Percent_Identity=35.2713178294574, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652985, Length=501, Percent_Identity=25.9481037924152, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19922090, Length=501, Percent_Identity=25.9481037924152, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24652981, Length=501, Percent_Identity=25.9481037924152, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24652983, Length=501, Percent_Identity=25.9481037924152, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644968, Length=481, Percent_Identity=26.6112266112266, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24648441, Length=186, Percent_Identity=38.1720430107527, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648439, Length=186, Percent_Identity=38.1720430107527, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648113, Length=461, Percent_Identity=26.0303687635575, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI161078093, Length=272, Percent_Identity=30.1470588235294, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356731, Length=220, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 48809; Mature: 48809

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCDRTASDILKDLARGALTVEALMQATLDRIGERNPALNAIVALRPTEDLMAEARAADA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHC
VPRAERGPLHGLPMAIKDLSNAKGLVTSQGSPIFAGQVAQEDDIFVARLRAAGVIVIGKT
CCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCEEECCCCCCCCHHHEEHHHCCEEEEECC
NTPEFGLGSHTYNPVYGATGNVVDPSRSAGGSSGGAAVALAAGMVALADGSDMMGSLRNP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCHHHHHHCCCC
AGWNEIYGFRPTWGWIPSEPVGDVFLHPLSTSGPMARTPEDLALLLDVMSGSDPRLPLAR
CCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHC
GAETVSPLKAPKPLRLGWLGDWGGAYPMDDGLLETCDAALQTFVEQGHTVERIAPPYPAE
CCCHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEHHCCCCCCHH
KIWQSWITLRSFAVAAGLRGLNNRRADLKEAALWELDRGLGFSAQEVQEASDLRSGWMRA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AARMFQRYDAVVLPTAQCWPFPIDWDYPKEIAGKPLDTYHRWMEVVVPASLLGLPALAVP
HHHHHHHCCCEEECCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHEEC
AGRGGADHLPIGLQIIGPHGSDGQILGLGQGYHTARAAL
CCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCHHHHCC
>Mature Secondary Structure
MLCDRTASDILKDLARGALTVEALMQATLDRIGERNPALNAIVALRPTEDLMAEARAADA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHC
VPRAERGPLHGLPMAIKDLSNAKGLVTSQGSPIFAGQVAQEDDIFVARLRAAGVIVIGKT
CCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCEEECCCCCCCCHHHEEHHHCCEEEEECC
NTPEFGLGSHTYNPVYGATGNVVDPSRSAGGSSGGAAVALAAGMVALADGSDMMGSLRNP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCHHHHHHCCCC
AGWNEIYGFRPTWGWIPSEPVGDVFLHPLSTSGPMARTPEDLALLLDVMSGSDPRLPLAR
CCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHC
GAETVSPLKAPKPLRLGWLGDWGGAYPMDDGLLETCDAALQTFVEQGHTVERIAPPYPAE
CCCHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEHHCCCCCCHH
KIWQSWITLRSFAVAAGLRGLNNRRADLKEAALWELDRGLGFSAQEVQEASDLRSGWMRA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AARMFQRYDAVVLPTAQCWPFPIDWDYPKEIAGKPLDTYHRWMEVVVPASLLGLPALAVP
HHHHHHHCCCEEECCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHEEC
AGRGGADHLPIGLQIIGPHGSDGQILGLGQGYHTARAAL
CCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]