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The map label for this gene is lytE [H]

Identifier: 94985488

GI number: 94985488

Start: 1470617

End: 1471528

Strand: Reverse

Name: lytE [H]

Synonym: Dgeo_1388

Alternate gene names: 94985488

Gene position: 1471528-1470617 (Counterclockwise)

Preceding gene: 94985490

Following gene: 94985486

Centisome position: 59.64

GC content: 67.87

Gene sequence:

>912_bases
ATGCCTGTGTTTTCCCGCACTGCCCTGCTGCTGGCCCTCCTGACCTTCACTGGAGCCGTGTCGCTCGCGCGGGCTGTTGA
GAGTCCTGTTGCCCTGGGAGGCGCGCCGCTCCCGGGAGTTGCAACTGCCCAGGCCGACACGGTCACCGTGCAGCCTGGCG
ACACGGCCTACAGTCTCGCACGCCGCAACGGACTGAGTGTGGACGCCCTGCTGGCGCTCAATGGCCTGAGCAGTCCGAAC
CTTCAGGTCGGACAGGTGCTGCGTGTGCGCGACGTACCGTCCTACACCGCATCCTACACGGTCCAGCGCGGCGACACCCT
GTACTCGCTGGCCCGCCGCTTCGGCGTCAGCGTGGAGATGCTGCTGGCGGCCAACACTCTGCCCAAGGACGTGATGTTGG
CAGTTGGGCAGGTGTTGCGTGTGCCTTCTGCTGGGCGTGAGGCGGCGCGTCCAGCCCCGGCCAGTCCCGCCTCCAGCCTG
CTCGCGCCGGGCATGACGGAGGCCGCGCCTTCTGGCGACTGGCGCGCGGCGGCCCTCGCGCTGCTGGGGACGCCCTATGT
TTACGGCGGCACCTCACCCAGCGGAACAGATTGCAGCGGCCTCGTCGTGCAGGTCTTTGCGGCGCTGGGGATCCAGCTTC
CTCGTCGCAGTGCTGACCAGGCGCAGCTTGGGGTGCCGGTCACCCCCGCCGAGCTGCAACCTGGCGACCTGGTCTTCTTC
GACACGGAGGGGCGCGGTGCCGTCACGCATGTCGGCATCTACCTGGGAGATGATCAGTTCGTCAATGCCAATTCCTACAA
GGGCCAGGTCGCGGTCGATCACCTCCTGAGCGATCCCTACTGGGCACCGCGACTGTTGGGTGCTCGCCGGGTGCTGCCTG
CGTCCCCCCCGTTCTACGCGAGCAGCCACTGA

Upstream 100 bases:

>100_bases
TCTGCTTCAGTTTTCTTTGCGCTGTTCTCATGCAGCGTTTGTGCTCACTGCATTTTGGTGGCTTCCGCCTGAATTGTTCC
GCGCCCTGTGAGTCCTCTTC

Downstream 100 bases:

>100_bases
TTTACCCCCAGAACCCGACACTCCAAAAAAGGTCTAGGCGCCGCTCCAATGTAGGGCGGCGTTTGAGCCGCAGGGCCAAG
CTGTCTCAGCCCTGCTCGTC

Product: NLP/P60

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPVFSRTALLLALLTFTGAVSLARAVESPVALGGAPLPGVATAQADTVTVQPGDTAYSLARRNGLSVDALLALNGLSSPN
LQVGQVLRVRDVPSYTASYTVQRGDTLYSLARRFGVSVEMLLAANTLPKDVMLAVGQVLRVPSAGREAARPAPASPASSL
LAPGMTEAAPSGDWRAAALALLGTPYVYGGTSPSGTDCSGLVVQVFAALGIQLPRRSADQAQLGVPVTPAELQPGDLVFF
DTEGRGAVTHVGIYLGDDQFVNANSYKGQVAVDHLLSDPYWAPRLLGARRVLPASPPFYASSH

Sequences:

>Translated_303_residues
MPVFSRTALLLALLTFTGAVSLARAVESPVALGGAPLPGVATAQADTVTVQPGDTAYSLARRNGLSVDALLALNGLSSPN
LQVGQVLRVRDVPSYTASYTVQRGDTLYSLARRFGVSVEMLLAANTLPKDVMLAVGQVLRVPSAGREAARPAPASPASSL
LAPGMTEAAPSGDWRAAALALLGTPYVYGGTSPSGTDCSGLVVQVFAALGIQLPRRSADQAQLGVPVTPAELQPGDLVFF
DTEGRGAVTHVGIYLGDDQFVNANSYKGQVAVDHLLSDPYWAPRLLGARRVLPASPPFYASSH
>Mature_302_residues
PVFSRTALLLALLTFTGAVSLARAVESPVALGGAPLPGVATAQADTVTVQPGDTAYSLARRNGLSVDALLALNGLSSPNL
QVGQVLRVRDVPSYTASYTVQRGDTLYSLARRFGVSVEMLLAANTLPKDVMLAVGQVLRVPSAGREAARPAPASPASSLL
APGMTEAAPSGDWRAAALALLGTPYVYGGTSPSGTDCSGLVVQVFAALGIQLPRRSADQAQLGVPVTPAELQPGDLVFFD
TEGRGAVTHVGIYLGDDQFVNANSYKGQVAVDHLLSDPYWAPRLLGARRVLPASPPFYASSH

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=118, Percent_Identity=39.8305084745763, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788501, Length=124, Percent_Identity=38.7096774193548, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788001, Length=110, Percent_Identity=42.7272727272727, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786421, Length=115, Percent_Identity=40, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 31389; Mature: 31258

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVFSRTALLLALLTFTGAVSLARAVESPVALGGAPLPGVATAQADTVTVQPGDTAYSLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEECCCCEEEECCCCHHHHHH
RRNGLSVDALLALNGLSSPNLQVGQVLRVRDVPSYTASYTVQRGDTLYSLARRFGVSVEM
HHCCCCEEEEEEECCCCCCCCHHHCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCEEE
LLAANTLPKDVMLAVGQVLRVPSAGREAARPAPASPASSLLAPGMTEAAPSGDWRAAALA
EEECCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHH
LLGTPYVYGGTSPSGTDCSGLVVQVFAALGIQLPRRSADQAQLGVPVTPAELQPGDLVFF
HHCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEE
DTEGRGAVTHVGIYLGDDQFVNANSYKGQVAVDHLLSDPYWAPRLLGARRVLPASPPFYA
ECCCCCCEEEEEEEECCCCEECCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCC
SSH
CCC
>Mature Secondary Structure 
PVFSRTALLLALLTFTGAVSLARAVESPVALGGAPLPGVATAQADTVTVQPGDTAYSLA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEECCCCEEEECCCCHHHHHH
RRNGLSVDALLALNGLSSPNLQVGQVLRVRDVPSYTASYTVQRGDTLYSLARRFGVSVEM
HHCCCCEEEEEEECCCCCCCCHHHCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCEEE
LLAANTLPKDVMLAVGQVLRVPSAGREAARPAPASPASSLLAPGMTEAAPSGDWRAAALA
EEECCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHH
LLGTPYVYGGTSPSGTDCSGLVVQVFAALGIQLPRRSADQAQLGVPVTPAELQPGDLVFF
HHCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEE
DTEGRGAVTHVGIYLGDDQFVNANSYKGQVAVDHLLSDPYWAPRLLGARRVLPASPPFYA
ECCCCCCEEEEEEEECCCCEECCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCC
SSH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]