Click here to switch to the map view.

The map label for this gene is murA

Identifier: 94985486

GI number: 94985486

Start: 1468680

End: 1469963

Strand: Reverse

Name: murA

Synonym: Dgeo_1386

Alternate gene names: 94985486

Gene position: 1469963-1468680 (Counterclockwise)

Preceding gene: 94985488

Following gene: 94985484

Centisome position: 59.58

GC content: 65.5

Gene sequence:

>1284_bases
ATGCAATTGACGCCGCTGCACATCCAGGGAGGCCGGAACCTGTCCGGTGAGATCGCCATTCAGCCCAGCAAGAATGCGGC
GTTGCCGATCATCGTGGCCAGCCTCCTGAGCAGTGAGCCTGTCACCCTGCACGGGGTGCCCCGCCTTTCGGACGTGTACA
CCATCCTTGAACTTGCGCACCACATCGGCACACGGCACGTCTGGACCGGCCCCAACAGCCTCACGCTGCACACGCCCGAG
ATCCTGAACACCGACGCGCCCTACGCCCTGGTCAGCAAGATGCGCGCCAGCTTCATCATGATGGGCGCTTTGCTCGCCCG
CGCCGGCGAGGCCACCGTCTCTATGCCGGGTGGGTGCGCCTTCGGATACCGCCCCGTTGATCAGCATGTCAAGGCGTTTC
GGGCGCTGGGGGTGCACATTGTCGAGGAGGGGGGCAACTTCGAGGCGCGGCGCGAGGGCAGCCTGAACGGTGCTTTCGTC
TTTGAGCTGCTGACTGTGGGCGGCACCCAGAACGCGATCCTGGCGTCGGTCCTAGGAGACGGCGTGGTCACGCTGGAAAA
CGCCAGCATCGACACCGATGTGGTGGACCTCATCAACTTCCTCAACAGCCTGGGTGCACAGATCCAGGGCGGCGGGACCA
ACACGCTCACCATTCGCGGAGTGAGGGCGCTGCGCGGCGGTGAGTACCGCATCATTCCAGACCGCATCGAGGCCGGAACC
TTTATGATCGCCGCCGCCGCCACCCGCAGCCGCCTCACGCTGACCAATGTCCGCCCCGACCACCTGCGTGCGGTCAGCAG
CAAGCTGATGGAGATGGGGGTGGACATCCTGGAGACGGAAGGCCGCCTGATTGTGGACGCTCGGGACCGCGAGCTGAAAC
CCGTCAACGTCACCACCCAGAGTTTCCCCGGCTTTCCGACCGACGTGCAGCCGCAGATGAGCGCCCTGCTCGCCACGGTT
CCCGGCACCAGTGTGGTGCAGGACCCGGTGTATCCCGATCGCCTCACCCATGTCGCAGAACTGCACCGCATGGGCGCAAA
TATCACCGTCAGCGGCTACACCCAGGTGATCCAGGGGGGTACCCTCCACGCCGCGCCCGTCAAGGCTGCTGATTTGCGCG
CTGGAGCTGCCCTCTTCATCGCTGCTCTCACCACTGAGGGCGAGACGGTCATCGAGGGTGTGCAGTACCTCAACCGCGGC
TACGAGCGACTGGCCGAGCGGCTGCGCTCCATCGGCGCCAACGCCTGGCAGCCTCAGCCGGTGCTGGCCAGCGCGATGGA
TTGA

Upstream 100 bases:

>100_bases
GAGCATCATGTGTAACATGCACTCAGTTTGACGTCGGGTTGTTCCGCAACGCCCCTCACCCCTTGAGCGCGGGAACTGCC
GCGCTGCCGAAAGGATCCCC

Downstream 100 bases:

>100_bases
GTGTCACCCTGATGTGCATGTGCGCCTGACGCCACAGCGGAACGGCGGACGGTTGGGAAGAGGTGGAAGGGCTGGGTGGG
AGGACAATGCCTGTTTCCGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MQLTPLHIQGGRNLSGEIAIQPSKNAALPIIVASLLSSEPVTLHGVPRLSDVYTILELAHHIGTRHVWTGPNSLTLHTPE
ILNTDAPYALVSKMRASFIMMGALLARAGEATVSMPGGCAFGYRPVDQHVKAFRALGVHIVEEGGNFEARREGSLNGAFV
FELLTVGGTQNAILASVLGDGVVTLENASIDTDVVDLINFLNSLGAQIQGGGTNTLTIRGVRALRGGEYRIIPDRIEAGT
FMIAAAATRSRLTLTNVRPDHLRAVSSKLMEMGVDILETEGRLIVDARDRELKPVNVTTQSFPGFPTDVQPQMSALLATV
PGTSVVQDPVYPDRLTHVAELHRMGANITVSGYTQVIQGGTLHAAPVKAADLRAGAALFIAALTTEGETVIEGVQYLNRG
YERLAERLRSIGANAWQPQPVLASAMD

Sequences:

>Translated_427_residues
MQLTPLHIQGGRNLSGEIAIQPSKNAALPIIVASLLSSEPVTLHGVPRLSDVYTILELAHHIGTRHVWTGPNSLTLHTPE
ILNTDAPYALVSKMRASFIMMGALLARAGEATVSMPGGCAFGYRPVDQHVKAFRALGVHIVEEGGNFEARREGSLNGAFV
FELLTVGGTQNAILASVLGDGVVTLENASIDTDVVDLINFLNSLGAQIQGGGTNTLTIRGVRALRGGEYRIIPDRIEAGT
FMIAAAATRSRLTLTNVRPDHLRAVSSKLMEMGVDILETEGRLIVDARDRELKPVNVTTQSFPGFPTDVQPQMSALLATV
PGTSVVQDPVYPDRLTHVAELHRMGANITVSGYTQVIQGGTLHAAPVKAADLRAGAALFIAALTTEGETVIEGVQYLNRG
YERLAERLRSIGANAWQPQPVLASAMD
>Mature_427_residues
MQLTPLHIQGGRNLSGEIAIQPSKNAALPIIVASLLSSEPVTLHGVPRLSDVYTILELAHHIGTRHVWTGPNSLTLHTPE
ILNTDAPYALVSKMRASFIMMGALLARAGEATVSMPGGCAFGYRPVDQHVKAFRALGVHIVEEGGNFEARREGSLNGAFV
FELLTVGGTQNAILASVLGDGVVTLENASIDTDVVDLINFLNSLGAQIQGGGTNTLTIRGVRALRGGEYRIIPDRIEAGT
FMIAAAATRSRLTLTNVRPDHLRAVSSKLMEMGVDILETEGRLIVDARDRELKPVNVTTQSFPGFPTDVQPQMSALLATV
PGTSVVQDPVYPDRLTHVAELHRMGANITVSGYTQVIQGGTLHAAPVKAADLRAGAALFIAALTTEGETVIEGVQYLNRG
YERLAERLRSIGANAWQPQPVLASAMD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=414, Percent_Identity=41.5458937198068, Blast_Score=315, Evalue=5e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_DEIGD (Q1IYK3)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_604850.1
- ProteinModelPortal:   Q1IYK3
- SMR:   Q1IYK3
- STRING:   Q1IYK3
- GeneID:   4057545
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_1386
- NMPDR:   fig|68909.1.peg.740
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   DGEO319795:DGEO_1386-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45536; Mature: 45536

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTPLHIQGGRNLSGEIAIQPSKNAALPIIVASLLSSEPVTLHGVPRLSDVYTILELAH
CCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
HIGTRHVWTGPNSLTLHTPEILNTDAPYALVSKMRASFIMMGALLARAGEATVSMPGGCA
HHCCCEEECCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
FGYRPVDQHVKAFRALGVHIVEEGGNFEARREGSLNGAFVFELLTVGGTQNAILASVLGD
CCCCCHHHHHHHHHHHCEEEEECCCCCCEECCCCCCCEEEEEEECCCCCCHHHHHHHHCC
GVVTLENASIDTDVVDLINFLNSLGAQIQGGGTNTLTIRGVRALRGGEYRIIPDRIEAGT
CEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCEEEEEEEEHHCCCCEEEECCCCCCCE
FMIAAAATRSRLTLTNVRPDHLRAVSSKLMEMGVDILETEGRLIVDARDRELKPVNVTTQ
EEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCCEEEECC
SFPGFPTDVQPQMSALLATVPGTSVVQDPVYPDRLTHVAELHRMGANITVSGYTQVIQGG
CCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHCCC
TLHAAPVKAADLRAGAALFIAALTTEGETVIEGVQYLNRGYERLAERLRSIGANAWQPQP
CEEECCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VLASAMD
HHHCCCC
>Mature Secondary Structure
MQLTPLHIQGGRNLSGEIAIQPSKNAALPIIVASLLSSEPVTLHGVPRLSDVYTILELAH
CCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
HIGTRHVWTGPNSLTLHTPEILNTDAPYALVSKMRASFIMMGALLARAGEATVSMPGGCA
HHCCCEEECCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
FGYRPVDQHVKAFRALGVHIVEEGGNFEARREGSLNGAFVFELLTVGGTQNAILASVLGD
CCCCCHHHHHHHHHHHCEEEEECCCCCCEECCCCCCCEEEEEEECCCCCCHHHHHHHHCC
GVVTLENASIDTDVVDLINFLNSLGAQIQGGGTNTLTIRGVRALRGGEYRIIPDRIEAGT
CEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCEEEEEEEEHHCCCCEEEECCCCCCCE
FMIAAAATRSRLTLTNVRPDHLRAVSSKLMEMGVDILETEGRLIVDARDRELKPVNVTTQ
EEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCCEEEECC
SFPGFPTDVQPQMSALLATVPGTSVVQDPVYPDRLTHVAELHRMGANITVSGYTQVIQGG
CCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHCCC
TLHAAPVKAADLRAGAALFIAALTTEGETVIEGVQYLNRGYERLAERLRSIGANAWQPQP
CEEECCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VLASAMD
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA