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The map label for this gene is katA [H]

Identifier: 94972195

GI number: 94972195

Start: 298866

End: 300497

Strand: Direct

Name: katA [H]

Synonym: Dgeo_2728

Alternate gene names: 94972195

Gene position: 298866-300497 (Clockwise)

Preceding gene: 94972197

Following gene: 94972194

Centisome position: 52.06

GC content: 63.11

Gene sequence:

>1632_bases
ATGAGCGACCAGAAGCAACCCAAGAACACCGGCATCGCCGGAACTGCCGTCGAAGGGATGGGCAGCCCCGCCGACACCCG
GTTTGCCCCCGGCGAGCAGGCGCAGACCCTCACCACCCGCCAGGGCCACCCGGTGACCAACAACCAGAACCTGCGCACGG
TCGGCAACCGCGGCCCGGCGACGCTGGAAAACTACCACTTCATCGAGAAGCTCTCTCATTTTGATCGCGAGCGCATTCCC
GAACGGGTGGTACACGCTCGCGGGGCCGGCGCACACGGCTACTTCGAGGCCTATGGCAAGGTCGGGGACGAGCCGATCAG
CCGCTACACCCGCGCCAAGCTTTTCCAGGAGCCGGGCAAGCGCACCCCGGTGTTCGTGCGGTTCTCAACGGTAGGACACG
GCGGGCACTCACCGGAGACCCTGCGCGACCCGCGCGGTTTTGCGGTGAAGTTCTACACCGAAGATGGCAACTGGGATCTT
GTCGGCAACAACCTCAAGGTCTTTTTTATCCGTGACGCAATCAAATTTCCTGACCTGATTCACTCGCAGAAGCCCGATCC
GGTCACCAACATCCAGAGCCAGGAACGGATCTTTGACTTCTTCTGCGGCACGCCCGAAGCGCTGCACATGATCACCCTGC
TGTACTCGCCCTGGGGCATCCCGGCGAGCTACCGCCACATGCAGGGGTCAGGCGTGAACACCTACAAGTGGGTAAACGAC
AAAGGCGAGGCGGTGCTGGTGAAGTATCACTGGGAACCCCTCCAGGGCATTCGCAATCTGACACAGGCGGAGGCCGAGGC
CATCCAGGCCAAAAACTTCAACCACGCGACCCAGGATCTCTACGAGGCCATCGAGCGCGGTGACTACCCGCAGTGGGAGT
TGCTGGTCCAGATCATGCCGGACGGCGAGCATCCTGAACTCGACTTTGATCCACTCGACGACACCAAAATCTGGCCGCGC
GACCAGTTCCCCTGGCTGCCAGTGGGCCGGATGACCCTCAACCGCAATCCCGAGAACTACTTTGCCGAAGTCGAGCAGGC
CGCCTTTGGAACCGGCGTCTTGGTGGACGGGCTGGACTTCAGCGATGACAAGATGCTCCAGGGCCGCACCTTCGCGTATT
CGGACACCCAGCGCTACCGCATCGGCCCCAACTACCTGCAACTGCCGATCAACGCCCCCAAAAAGCATGTGGCCACCAAC
CAGCGCGACGGGCAGATGACCTACCGGGTGGACACGGCCCCCGGCCAGAATCCGCACGTGAACTACGAGCCTTCCACGCT
CAATGGCCTCTCGGAAGCGCCCCGCCAGGCGCCCGACCACACGCCCTACATCGCGGGCAACCTGGTGCGCCAGAGCATCG
ACCGGACCAACGACTTCAAGCAGGCGGGCGAGCAGTACCGCGCCTTCGAAGATTGGGAACGCGACGAGCTGATCAGCAAC
CTGGTGGCGAGCCTCAAGGATACGGCCCAGCACATCCAGGACAAGATGATCGAGTATTTCACCCAGGCGGACCCCGACTA
TGGCCGCCGCGTGCGTGAAGGGATCGCCCAAGCCCGCCAGAGTGACGCCCAGAAGAAGGCAGAGGCGGTGCAGCAGGCCG
AAGAGCGCAGCCACGAGGCGCAGCCCTACTGA

Upstream 100 bases:

>100_bases
GAAAAAGTCATAATGATTATGATTTTGGAGCTTAAGCACGGCGACAGCGGTGCCGCCCCGTCTCACCCTCACCCCAGCCA
GGCAGCTGAACAGGAGACCT

Downstream 100 bases:

>100_bases
GGCCTCGCTGCTCACCAAGGCTCGGCCCTCCTGGCGCGTGCCCGGATGGTGCCCTGCCGCTGCGAAAAGCCGGACCACCT
GCTACCCTAAGGGAGAAGCA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MSDQKQPKNTGIAGTAVEGMGSPADTRFAPGEQAQTLTTRQGHPVTNNQNLRTVGNRGPATLENYHFIEKLSHFDRERIP
ERVVHARGAGAHGYFEAYGKVGDEPISRYTRAKLFQEPGKRTPVFVRFSTVGHGGHSPETLRDPRGFAVKFYTEDGNWDL
VGNNLKVFFIRDAIKFPDLIHSQKPDPVTNIQSQERIFDFFCGTPEALHMITLLYSPWGIPASYRHMQGSGVNTYKWVND
KGEAVLVKYHWEPLQGIRNLTQAEAEAIQAKNFNHATQDLYEAIERGDYPQWELLVQIMPDGEHPELDFDPLDDTKIWPR
DQFPWLPVGRMTLNRNPENYFAEVEQAAFGTGVLVDGLDFSDDKMLQGRTFAYSDTQRYRIGPNYLQLPINAPKKHVATN
QRDGQMTYRVDTAPGQNPHVNYEPSTLNGLSEAPRQAPDHTPYIAGNLVRQSIDRTNDFKQAGEQYRAFEDWERDELISN
LVASLKDTAQHIQDKMIEYFTQADPDYGRRVREGIAQARQSDAQKKAEAVQQAEERSHEAQPY

Sequences:

>Translated_543_residues
MSDQKQPKNTGIAGTAVEGMGSPADTRFAPGEQAQTLTTRQGHPVTNNQNLRTVGNRGPATLENYHFIEKLSHFDRERIP
ERVVHARGAGAHGYFEAYGKVGDEPISRYTRAKLFQEPGKRTPVFVRFSTVGHGGHSPETLRDPRGFAVKFYTEDGNWDL
VGNNLKVFFIRDAIKFPDLIHSQKPDPVTNIQSQERIFDFFCGTPEALHMITLLYSPWGIPASYRHMQGSGVNTYKWVND
KGEAVLVKYHWEPLQGIRNLTQAEAEAIQAKNFNHATQDLYEAIERGDYPQWELLVQIMPDGEHPELDFDPLDDTKIWPR
DQFPWLPVGRMTLNRNPENYFAEVEQAAFGTGVLVDGLDFSDDKMLQGRTFAYSDTQRYRIGPNYLQLPINAPKKHVATN
QRDGQMTYRVDTAPGQNPHVNYEPSTLNGLSEAPRQAPDHTPYIAGNLVRQSIDRTNDFKQAGEQYRAFEDWERDELISN
LVASLKDTAQHIQDKMIEYFTQADPDYGRRVREGIAQARQSDAQKKAEAVQQAEERSHEAQPY
>Mature_542_residues
SDQKQPKNTGIAGTAVEGMGSPADTRFAPGEQAQTLTTRQGHPVTNNQNLRTVGNRGPATLENYHFIEKLSHFDRERIPE
RVVHARGAGAHGYFEAYGKVGDEPISRYTRAKLFQEPGKRTPVFVRFSTVGHGGHSPETLRDPRGFAVKFYTEDGNWDLV
GNNLKVFFIRDAIKFPDLIHSQKPDPVTNIQSQERIFDFFCGTPEALHMITLLYSPWGIPASYRHMQGSGVNTYKWVNDK
GEAVLVKYHWEPLQGIRNLTQAEAEAIQAKNFNHATQDLYEAIERGDYPQWELLVQIMPDGEHPELDFDPLDDTKIWPRD
QFPWLPVGRMTLNRNPENYFAEVEQAAFGTGVLVDGLDFSDDKMLQGRTFAYSDTQRYRIGPNYLQLPINAPKKHVATNQ
RDGQMTYRVDTAPGQNPHVNYEPSTLNGLSEAPRQAPDHTPYIAGNLVRQSIDRTNDFKQAGEQYRAFEDWERDELISNL
VASLKDTAQHIQDKMIEYFTQADPDYGRRVREGIAQARQSDAQKKAEAVQQAEERSHEAQPY

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=503, Percent_Identity=44.1351888667992, Blast_Score=429, Evalue=1e-120,
Organism=Escherichia coli, GI48994891, Length=426, Percent_Identity=45.7746478873239, Blast_Score=371, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71998444, Length=491, Percent_Identity=43.7881873727088, Blast_Score=437, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI25147792, Length=490, Percent_Identity=42.4489795918367, Blast_Score=427, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI25151141, Length=491, Percent_Identity=42.1588594704684, Blast_Score=425, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6320462, Length=498, Percent_Identity=38.9558232931727, Blast_Score=327, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6321525, Length=510, Percent_Identity=32.3529411764706, Blast_Score=263, Evalue=5e-71,
Organism=Drosophila melanogaster, GI17981717, Length=491, Percent_Identity=44.1955193482688, Blast_Score=419, Evalue=1e-117,
Organism=Drosophila melanogaster, GI19920968, Length=495, Percent_Identity=41.2121212121212, Blast_Score=402, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 61705; Mature: 61574

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQKQPKNTGIAGTAVEGMGSPADTRFAPGEQAQTLTTRQGHPVTNNQNLRTVGNRGPA
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCC
TLENYHFIEKLSHFDRERIPERVVHARGAGAHGYFEAYGKVGDEPISRYTRAKLFQEPGK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC
RTPVFVRFSTVGHGGHSPETLRDPRGFAVKFYTEDGNWDLVGNNLKVFFIRDAIKFPDLI
CCCEEEEEEECCCCCCCCHHHCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHCHHHH
HSQKPDPVTNIQSQERIFDFFCGTPEALHMITLLYSPWGIPASYRHMQGSGVNTYKWVND
HCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEECC
KGEAVLVKYHWEPLQGIRNLTQAEAEAIQAKNFNHATQDLYEAIERGDYPQWELLVQIMP
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECC
DGEHPELDFDPLDDTKIWPRDQFPWLPVGRMTLNRNPENYFAEVEQAAFGTGVLVDGLDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEECCCC
SDDKMLQGRTFAYSDTQRYRIGPNYLQLPINAPKKHVATNQRDGQMTYRVDTAPGQNPHV
CCCCCCCCCEEEECCCCCEEECCCEEEECCCCCHHHHCCCCCCCEEEEEEECCCCCCCCC
NYEPSTLNGLSEAPRQAPDHTPYIAGNLVRQSIDRTNDFKQAGEQYRAFEDWERDELISN
CCCCHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVASLKDTAQHIQDKMIEYFTQADPDYGRRVREGIAQARQSDAQKKAEAVQQAEERSHEA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPY
CCC
>Mature Secondary Structure 
SDQKQPKNTGIAGTAVEGMGSPADTRFAPGEQAQTLTTRQGHPVTNNQNLRTVGNRGPA
CCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCC
TLENYHFIEKLSHFDRERIPERVVHARGAGAHGYFEAYGKVGDEPISRYTRAKLFQEPGK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC
RTPVFVRFSTVGHGGHSPETLRDPRGFAVKFYTEDGNWDLVGNNLKVFFIRDAIKFPDLI
CCCEEEEEEECCCCCCCCHHHCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHCHHHH
HSQKPDPVTNIQSQERIFDFFCGTPEALHMITLLYSPWGIPASYRHMQGSGVNTYKWVND
HCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEECC
KGEAVLVKYHWEPLQGIRNLTQAEAEAIQAKNFNHATQDLYEAIERGDYPQWELLVQIMP
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECC
DGEHPELDFDPLDDTKIWPRDQFPWLPVGRMTLNRNPENYFAEVEQAAFGTGVLVDGLDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEECCCC
SDDKMLQGRTFAYSDTQRYRIGPNYLQLPINAPKKHVATNQRDGQMTYRVDTAPGQNPHV
CCCCCCCCCEEEECCCCCEEECCCEEEECCCCCHHHHCCCCCCCEEEEEEECCCCCCCCC
NYEPSTLNGLSEAPRQAPDHTPYIAGNLVRQSIDRTNDFKQAGEQYRAFEDWERDELISN
CCCCHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVASLKDTAQHIQDKMIEYFTQADPDYGRRVREGIAQARQSDAQKKAEAVQQAEERSHEA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPY
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]