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The map label for this gene is perR [H]

Identifier: 94972194

GI number: 94972194

Start: 300597

End: 301004

Strand: Direct

Name: perR [H]

Synonym: Dgeo_2727

Alternate gene names: 94972194

Gene position: 300597-301004 (Clockwise)

Preceding gene: 94972195

Following gene: 94972193

Centisome position: 52.36

GC content: 62.99

Gene sequence:

>408_bases
ATGTCCACAGCAGAACTTCAGCACCACCTGGAACGTCGGCAGCTGCGCGTCACACAACCGCGGCTGAGACTGCTGGAGTT
CTTTGCCCGCAGCAGCGGCCACTTTACCCCTGAGGAAATCTCGGAGCAGTTGCGCGCGCAGGGGCATCCCATCAGCCTCG
CCACGCTGTATCAGAACCTCAAGATCTTCAGCGAGCACGGGCTCATCAAGGAGATGATCGGGCAAAACGGCGAGGTGCGC
TATGACACCAATCTTGAGCCGCACTCGCATCTGATCTGCTTGCGCTGCGGCCGATTGGTGGACGTGGTGCTCGAACTGCC
GCAGCTGACGCCCACTGGCCCGGGGCAGGGCTGGGTCATCGCCGGGGCACGGGTGGACTTGCAGGGCATCTGTCCGGCGT
GCCAGTGA

Upstream 100 bases:

>100_bases
AGGCCTCGCTGCTCACCAAGGCTCGGCCCTCCTGGCGCGTGCCCGGATGGTGCCCTGCCGCTGCGAAAAGCCGGACCACC
TGCTACCCTAAGGGAGAAGC

Downstream 100 bases:

>100_bases
TGGGCCGCGCCCCCAAGGCCTGAACAACGAGGCCCGATGAGACGCACGGGGAAAGTCCTCGTGCGTTTTTGCGTCTGGGC
CAGCGCGTAGTCCTGCCGCG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MSTAELQHHLERRQLRVTQPRLRLLEFFARSSGHFTPEEISEQLRAQGHPISLATLYQNLKIFSEHGLIKEMIGQNGEVR
YDTNLEPHSHLICLRCGRLVDVVLELPQLTPTGPGQGWVIAGARVDLQGICPACQ

Sequences:

>Translated_135_residues
MSTAELQHHLERRQLRVTQPRLRLLEFFARSSGHFTPEEISEQLRAQGHPISLATLYQNLKIFSEHGLIKEMIGQNGEVR
YDTNLEPHSHLICLRCGRLVDVVLELPQLTPTGPGQGWVIAGARVDLQGICPACQ
>Mature_134_residues
STAELQHHLERRQLRVTQPRLRLLEFFARSSGHFTPEEISEQLRAQGHPISLATLYQNLKIFSEHGLIKEMIGQNGEVRY
DTNLEPHSHLICLRCGRLVDVVLELPQLTPTGPGQGWVIAGARVDLQGICPACQ

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15215; Mature: 15084

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAELQHHLERRQLRVTQPRLRLLEFFARSSGHFTPEEISEQLRAQGHPISLATLYQNL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
KIFSEHGLIKEMIGQNGEVRYDTNLEPHSHLICLRCGRLVDVVLELPQLTPTGPGQGWVI
HHHHHCCHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
AGARVDLQGICPACQ
ECCEECCCCCCCCCC
>Mature Secondary Structure 
STAELQHHLERRQLRVTQPRLRLLEFFARSSGHFTPEEISEQLRAQGHPISLATLYQNL
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
KIFSEHGLIKEMIGQNGEVRYDTNLEPHSHLICLRCGRLVDVVLELPQLTPTGPGQGWVI
HHHHHCCHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
AGARVDLQGICPACQ
ECCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]