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The map label for this gene is ompR [H]

Identifier: 94312809

GI number: 94312809

Start: 425609

End: 426322

Strand: Direct

Name: ompR [H]

Synonym: Rmet_3881

Alternate gene names: 94312809

Gene position: 425609-426322 (Clockwise)

Preceding gene: 94312808

Following gene: 94312810

Centisome position: 16.5

GC content: 65.55

Gene sequence:

>714_bases
ATGGAGCAGGTGAACCGGATAATCGTGCTCGATGACGAGGCGGAGCTGCGCAATATGCTGCAGCGCTTCCTGACCGGGCA
TGGCTTTCACGTGCGTGCGGTGGCGGACGGCAAGCAACTCAATCGCTACCTGCAGCGCGAACCGTACGACCTGCTCGTGC
TCGATCTGATGATGGAGCCAGAGGATGGCCTCTCGGTCTGCCGCAGGCTTCGTGCCGAGGGCCAGACGCTGCCCATCCTG
ATGCTGACCGCCAAGGGCGATCCGGCCGATCGCGTGATCGGGCTCGATACCGGCGCGGACGACTATCTGGCCAAGCCGTT
CCTGCCCGACGAACTGGTGGCCCGCATCCGTGCGTTGCTGCGCCGCCAGAAGATCGCCGCCGGCGATCCCACCGTGGCTT
CCCAGACGCTGAGCTTTGGCGAGTTCCGCTTCGATGTCGGCAAGCAGACGCTGACGCGCGCGGGCGTGCCGGTGGAAGTG
CACTCTGCCCAGATGCTGCTGCTCCAGGCGCTGGGCGCTTCGCCAAACCGGCCGGTCAGCCGTGAGAACCTGCTGGCCCG
CGCGCGCGGCCGCGATCATGACGCGCTCGATCGCAGTATCGACGTGCAGATTCTGAGGCTGCGCCAGATCGTCGAGGAAG
ATCCGTCCAAACCACGCTTCATCAAGACGGTTTGGGGGGTGGGATACATGCTGGTGGCCGGCGTGGAGGCGTGA

Upstream 100 bases:

>100_bases
CGAGATCGACACGCAGCGCAGCGGCTATGTGACGCTGCGGCAGATCGAGATTTTCATGGCCCAACGGATGTCGGCTCGCT
GAACGCATGGGAGACGCGGC

Downstream 100 bases:

>100_bases
TGCGAATCGGACTGCCGCGCTCGCTGCTGGCTCGCAACATCGCGCTGCTGGTGGCGCTGGTGGCGTTCACGCAGGTGTGT
TCGCTGATGGTGCTGCTGCA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MEQVNRIIVLDDEAELRNMLQRFLTGHGFHVRAVADGKQLNRYLQREPYDLLVLDLMMEPEDGLSVCRRLRAEGQTLPIL
MLTAKGDPADRVIGLDTGADDYLAKPFLPDELVARIRALLRRQKIAAGDPTVASQTLSFGEFRFDVGKQTLTRAGVPVEV
HSAQMLLLQALGASPNRPVSRENLLARARGRDHDALDRSIDVQILRLRQIVEEDPSKPRFIKTVWGVGYMLVAGVEA

Sequences:

>Translated_237_residues
MEQVNRIIVLDDEAELRNMLQRFLTGHGFHVRAVADGKQLNRYLQREPYDLLVLDLMMEPEDGLSVCRRLRAEGQTLPIL
MLTAKGDPADRVIGLDTGADDYLAKPFLPDELVARIRALLRRQKIAAGDPTVASQTLSFGEFRFDVGKQTLTRAGVPVEV
HSAQMLLLQALGASPNRPVSRENLLARARGRDHDALDRSIDVQILRLRQIVEEDPSKPRFIKTVWGVGYMLVAGVEA
>Mature_237_residues
MEQVNRIIVLDDEAELRNMLQRFLTGHGFHVRAVADGKQLNRYLQREPYDLLVLDLMMEPEDGLSVCRRLRAEGQTLPIL
MLTAKGDPADRVIGLDTGADDYLAKPFLPDELVARIRALLRRQKIAAGDPTVASQTLSFGEFRFDVGKQTLTRAGVPVEV
HSAQMLLLQALGASPNRPVSRENLLARARGRDHDALDRSIDVQILRLRQIVEEDPSKPRFIKTVWGVGYMLVAGVEA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=49.7854077253219, Blast_Score=248, Evalue=2e-67,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=38.0952380952381, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=35.3448275862069, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=34.3347639484979, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=37.3390557939914, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=33.1858407079646, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.5132743362832, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=28.6919831223629, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=35.0649350649351, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.5789473684211, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=31.7391304347826, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.858407079646, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.0512820512821, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=31.1688311688312, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=34.3511450381679, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=32.7731092436975, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=31.858407079646, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26516; Mature: 26516

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVNRIIVLDDEAELRNMLQRFLTGHGFHVRAVADGKQLNRYLQREPYDLLVLDLMMEP
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEHCCC
EDGLSVCRRLRAEGQTLPILMLTAKGDPADRVIGLDTGADDYLAKPFLPDELVARIRALL
CHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCCCCHHHCCCCCCHHHHHHHHHHH
RRQKIAAGDPTVASQTLSFGEFRFDVGKQTLTRAGVPVEVHSAQMLLLQALGASPNRPVS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCC
RENLLARARGRDHDALDRSIDVQILRLRQIVEEDPSKPRFIKTVWGVGYMLVAGVEA
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEQVNRIIVLDDEAELRNMLQRFLTGHGFHVRAVADGKQLNRYLQREPYDLLVLDLMMEP
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEHCCC
EDGLSVCRRLRAEGQTLPILMLTAKGDPADRVIGLDTGADDYLAKPFLPDELVARIRALL
CHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCCCCHHHCCCCCCHHHHHHHHHHH
RRQKIAAGDPTVASQTLSFGEFRFDVGKQTLTRAGVPVEVHSAQMLLLQALGASPNRPVS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCC
RENLLARARGRDHDALDRSIDVQILRLRQIVEEDPSKPRFIKTVWGVGYMLVAGVEA
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]