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The map label for this gene is hmvB [H]

Identifier: 94312767

GI number: 94312767

Start: 379278

End: 380495

Strand: Direct

Name: hmvB [H]

Synonym: Rmet_3837

Alternate gene names: 94312767

Gene position: 379278-380495 (Clockwise)

Preceding gene: 94312766

Following gene: 94312768

Centisome position: 14.7

GC content: 67.32

Gene sequence:

>1218_bases
ATGCATCGCATCCCTGATATGCCGCTCATCTCCCGCGATTCCCGCTTCACCCGTGCCGGCGCCGCGCGTCTGGCGGCCGT
GCTGTCACTGTGCGTCCTTACGCTGGGCGCCTGCGGCAAGAAGGAAGCGCCCGAGAACGACGACGAGCCGAAGGTGGCTG
GTCAGGTCATCGAGTATCCGGCGAGCGTCAGGTCGCTGCCCGGCGTCGTCGGCCAGCCGGTCAAGAGCGGCGGCGATCGG
ATGCTGAGCATGCCCGGCCGTCTGGTCTGGAACGAGGACAAGACGGTGCGCGTGGCTTCGCCGTTCGCCGGCCGCGTGAT
GGAGATTCTGGTGCAGCCCGGCGCCACCGTGAAGGCAGGCCAGCCGCTGGCGATGCTGACGTCGCCCGATTTTGGCTCGG
CGCAGGCCGATGCCCGCAAGGCGTCCGCGGATAGCGCCGTGGCGTCGAAGGCGCTGGCGCGCCAGCGCGAGCTGTATGAG
GCCGGGGTCATCGCCCAGAAGGATCTGGAGCAGGCGCAGGCGGACAACGCGCGCGCCGCGGCTGACCAGCAGCGCACGCA
GGCAGCGCTGCGCATGTACGGCGCTTCCGGCAGCGACGGCGTGAACCAGCGTTTTGCGCTGCGCAGCCCGATCGACGGCC
TGGTGGTCGAGCGCAATATCAATCCGGGGATGGAACTGCGTCCCGACCAGCCGCCCACCGCACCGCTGTACCTGATCACC
GATCCCACGACGCTGTGGGCACAGCTCGATGCCGCCGAGGCGGACCTTGGCCACTTCAGGCCCGGCGTGACCGTGCAGCT
TGCCAGCGCCGCTTACCCCGGCGAGACGTTCACGGGCACCGTGGTCAAGATCGCGGATTACGTTGATCCGTCGTCGCGCA
GCGTCAAGGTGCGTCTGTCCGTGCCGAATGCCGACCGCCGCCTGAAGGCCGAGATGTTCGTTACGGCGAAGATGCAGGCC
GCGTCGTTCCAGGGGATCTCGGTGCCGTCGAAGGCCGTGTTCCTGGCCGACAACAAGAACTATGTGTTCGTGCGAACCAC
GCCTAACAGGTTCGAGCGCCGCGAGGTCAAGCTCGGCGTGACGATTCCGGGCACGACCGAGGTGGTGGAAGGCCTGAAAG
AGGGCGACGTGGTGATCACCGACGGCAATCTCTATCTGCAGGACATCCTGCGCGATGCCACCGCGGTGAATGCCGCGCGT
GCGACTGCCAAGCATTAA

Upstream 100 bases:

>100_bases
GTCGACGTGCAGGGCAACTTCGCCAAGGCCATGGCCGCCTACCGCGCCGCCCTGCAGGCCACCACTTCCGATATCAACAA
GCTTCCCCAGGTTCGAACCG

Downstream 100 bases:

>100_bases
GGACGGCAGCCACATGATTTCACGTATCGTCAATTTCGCGCTGCACCAGAAGCTGTTCGTCTGGCTTGGCCTGATCATCT
TCGTCGCGGGCGGCCTGGCC

Product: heavy metal cation tricomponent efflux, membrane fusion protein HmvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MHRIPDMPLISRDSRFTRAGAARLAAVLSLCVLTLGACGKKEAPENDDEPKVAGQVIEYPASVRSLPGVVGQPVKSGGDR
MLSMPGRLVWNEDKTVRVASPFAGRVMEILVQPGATVKAGQPLAMLTSPDFGSAQADARKASADSAVASKALARQRELYE
AGVIAQKDLEQAQADNARAAADQQRTQAALRMYGASGSDGVNQRFALRSPIDGLVVERNINPGMELRPDQPPTAPLYLIT
DPTTLWAQLDAAEADLGHFRPGVTVQLASAAYPGETFTGTVVKIADYVDPSSRSVKVRLSVPNADRRLKAEMFVTAKMQA
ASFQGISVPSKAVFLADNKNYVFVRTTPNRFERREVKLGVTIPGTTEVVEGLKEGDVVITDGNLYLQDILRDATAVNAAR
ATAKH

Sequences:

>Translated_405_residues
MHRIPDMPLISRDSRFTRAGAARLAAVLSLCVLTLGACGKKEAPENDDEPKVAGQVIEYPASVRSLPGVVGQPVKSGGDR
MLSMPGRLVWNEDKTVRVASPFAGRVMEILVQPGATVKAGQPLAMLTSPDFGSAQADARKASADSAVASKALARQRELYE
AGVIAQKDLEQAQADNARAAADQQRTQAALRMYGASGSDGVNQRFALRSPIDGLVVERNINPGMELRPDQPPTAPLYLIT
DPTTLWAQLDAAEADLGHFRPGVTVQLASAAYPGETFTGTVVKIADYVDPSSRSVKVRLSVPNADRRLKAEMFVTAKMQA
ASFQGISVPSKAVFLADNKNYVFVRTTPNRFERREVKLGVTIPGTTEVVEGLKEGDVVITDGNLYLQDILRDATAVNAAR
ATAKH
>Mature_405_residues
MHRIPDMPLISRDSRFTRAGAARLAAVLSLCVLTLGACGKKEAPENDDEPKVAGQVIEYPASVRSLPGVVGQPVKSGGDR
MLSMPGRLVWNEDKTVRVASPFAGRVMEILVQPGATVKAGQPLAMLTSPDFGSAQADARKASADSAVASKALARQRELYE
AGVIAQKDLEQAQADNARAAADQQRTQAALRMYGASGSDGVNQRFALRSPIDGLVVERNINPGMELRPDQPPTAPLYLIT
DPTTLWAQLDAAEADLGHFRPGVTVQLASAAYPGETFTGTVVKIADYVDPSSRSVKVRLSVPNADRRLKAEMFVTAKMQA
ASFQGISVPSKAVFLADNKNYVFVRTTPNRFERREVKLGVTIPGTTEVVEGLKEGDVVITDGNLYLQDILRDATAVNAAR
ATAKH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=307, Percent_Identity=25.4071661237785, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082036, Length=306, Percent_Identity=24.5098039215686, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43361; Mature: 43361

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIPDMPLISRDSRFTRAGAARLAAVLSLCVLTLGACGKKEAPENDDEPKVAGQVIEYP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC
ASVRSLPGVVGQPVKSGGDRMLSMPGRLVWNEDKTVRVASPFAGRVMEILVQPGATVKAG
HHHHHCCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEECCHHHHHHHHHHCCCCCEECC
QPLAMLTSPDFGSAQADARKASADSAVASKALARQRELYEAGVIAQKDLEQAQADNARAA
CCEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHH
ADQQRTQAALRMYGASGSDGVNQRFALRSPIDGLVVERNINPGMELRPDQPPTAPLYLIT
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEE
DPTTLWAQLDAAEADLGHFRPGVTVQLASAAYPGETFTGTVVKIADYVDPSSRSVKVRLS
CCCEEEEECCCHHCCHHHCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEEE
VPNADRRLKAEMFVTAKMQAASFQGISVPSKAVFLADNKNYVFVRTTPNRFERREVKLGV
CCCCCHHEEEEEEEEEEEHHHCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEEEEE
TIPGTTEVVEGLKEGDVVITDGNLYLQDILRDATAVNAARATAKH
ECCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHRIPDMPLISRDSRFTRAGAARLAAVLSLCVLTLGACGKKEAPENDDEPKVAGQVIEYP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC
ASVRSLPGVVGQPVKSGGDRMLSMPGRLVWNEDKTVRVASPFAGRVMEILVQPGATVKAG
HHHHHCCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEECCHHHHHHHHHHCCCCCEECC
QPLAMLTSPDFGSAQADARKASADSAVASKALARQRELYEAGVIAQKDLEQAQADNARAA
CCEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHH
ADQQRTQAALRMYGASGSDGVNQRFALRSPIDGLVVERNINPGMELRPDQPPTAPLYLIT
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEE
DPTTLWAQLDAAEADLGHFRPGVTVQLASAAYPGETFTGTVVKIADYVDPSSRSVKVRLS
CCCEEEEECCCHHCCHHHCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEEE
VPNADRRLKAEMFVTAKMQAASFQGISVPSKAVFLADNKNYVFVRTTPNRFERREVKLGV
CCCCCHHEEEEEEEEEEEHHHCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEEEEE
TIPGTTEVVEGLKEGDVVITDGNLYLQDILRDATAVNAARATAKH
ECCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]