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The map label for this gene is yeaP [H]

Identifier: 94312768

GI number: 94312768

Start: 383852

End: 384868

Strand: Direct

Name: yeaP [H]

Synonym: Rmet_3840

Alternate gene names: 94312768

Gene position: 383852-384868 (Clockwise)

Preceding gene: 94312767

Following gene: 94312769

Centisome position: 14.88

GC content: 62.14

Gene sequence:

>1017_bases
ATGGAGTTGATCCTTGAGCGGCTTTCGGAGTCCGTTGCCACGGCGGAGAATCTGGAGCAACTCACGAGACCGCTGCTGGA
GATGCTGGAACTGATCACCGGCCTTGAGTCCCTGTACCTGACGTCGATCGATGAAGAGGCGGGTTTGCAGTCCGTTGACT
TTGTCAGGAACGCGGGCGAACTTGTGATTCCCGAGGGGCTGTCCGTTCCATGGTCCGACACCCTCTGCAAGCGTTGCCTG
GAGGAAGGCCGCCGCTACACGTCGAACGCGAGCGAGATCTGGGGGGATTCACAGGCCGCGAGGGCGCTCGGCATCGAGAC
ATACGCCAGTGCCCCCATTCGCGCGAGCGATGGGGAGATCATTGGTACGTTGTGCGGGGCGAGCAAGCGCAGCCAACCGC
TGGGGCCGCAGGCGTTCAGCGCCTTGAACATCTTCTCGAAGCTGATTGGACACCATATCGAGCGAGAACGATTGCTTGAG
GAACTGAGGCGGTCGAACGAGTACCTCGCGAACTTCGCGTTGACCGACGCCCTGACGGGCCTGCCCAACAGACGGGCGCT
CCACGGAGAGCTTGGCAGACTGCTGGCGCGCGCAACCAGGGACGAATCCCACGTCGTCGTCGGCATCATCGATCTCGATG
ACTTCAAACGCATCAACGACTCATACGGACATGTGGTCGGAGACCAGTTCCTGAGCGAATGTTCAAAGCGCCTATCCGGC
ATTGTGCGAGACACCGACATGCTGGCCCGCGTGGGTGGCGACGAGTTTGCGCTGGTGGCGCCCTGTCCGGCGTCTGCAAC
GCAGGCGCATAGCCTGGCCGACCAATTGCAGAAGCGTGCGTTGGCGGCGACTCGCGGTGTCTACACGCTTGCCGACGTCA
CGATCGATTACGCTGGTGTGAGCGCAGGTGTCGTGGCCGTCAGGCCCGTCTCCGTCGAACAGGCGCTGGAACTGGCGGAC
GCCGCCATGTATCGCGAGAAGCGGCAACGCAAGCAATCTGGCCCAAACGGTGGGTGA

Upstream 100 bases:

>100_bases
GCAAAGCGATATGATTTCTCACTCAGCCGAGTTGGCCGGCAGGCGCCTGTTGCGGTATGTTCTAGAGCGAAAGCACAGCA
TGGAAGAGGAGACAAAACCC

Downstream 100 bases:

>100_bases
CCGCTTCAGCAATGACCGGCGCTGACACGCGTCCGGCCCGATGCTTCGGGCGCAACGCCCGGAGCAACCAATAAGCAGAC
AGCAACGGGCTGCCAGCCAG

Product: putative diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MELILERLSESVATAENLEQLTRPLLEMLELITGLESLYLTSIDEEAGLQSVDFVRNAGELVIPEGLSVPWSDTLCKRCL
EEGRRYTSNASEIWGDSQAARALGIETYASAPIRASDGEIIGTLCGASKRSQPLGPQAFSALNIFSKLIGHHIERERLLE
ELRRSNEYLANFALTDALTGLPNRRALHGELGRLLARATRDESHVVVGIIDLDDFKRINDSYGHVVGDQFLSECSKRLSG
IVRDTDMLARVGGDEFALVAPCPASATQAHSLADQLQKRALAATRGVYTLADVTIDYAGVSAGVVAVRPVSVEQALELAD
AAMYREKRQRKQSGPNGG

Sequences:

>Translated_338_residues
MELILERLSESVATAENLEQLTRPLLEMLELITGLESLYLTSIDEEAGLQSVDFVRNAGELVIPEGLSVPWSDTLCKRCL
EEGRRYTSNASEIWGDSQAARALGIETYASAPIRASDGEIIGTLCGASKRSQPLGPQAFSALNIFSKLIGHHIERERLLE
ELRRSNEYLANFALTDALTGLPNRRALHGELGRLLARATRDESHVVVGIIDLDDFKRINDSYGHVVGDQFLSECSKRLSG
IVRDTDMLARVGGDEFALVAPCPASATQAHSLADQLQKRALAATRGVYTLADVTIDYAGVSAGVVAVRPVSVEQALELAD
AAMYREKRQRKQSGPNGG
>Mature_338_residues
MELILERLSESVATAENLEQLTRPLLEMLELITGLESLYLTSIDEEAGLQSVDFVRNAGELVIPEGLSVPWSDTLCKRCL
EEGRRYTSNASEIWGDSQAARALGIETYASAPIRASDGEIIGTLCGASKRSQPLGPQAFSALNIFSKLIGHHIERERLLE
ELRRSNEYLANFALTDALTGLPNRRALHGELGRLLARATRDESHVVVGIIDLDDFKRINDSYGHVVGDQFLSECSKRLSG
IVRDTDMLARVGGDEFALVAPCPASATQAHSLADQLQKRALAATRGVYTLADVTIDYAGVSAGVVAVRPVSVEQALELAD
AAMYREKRQRKQSGPNGG

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger (Probable). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081977, Length=332, Percent_Identity=41.2650602409639, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=33.7209302325581, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=34.3949044585987, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788956, Length=182, Percent_Identity=32.4175824175824, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788381, Length=190, Percent_Identity=32.1052631578947, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786584, Length=158, Percent_Identity=31.0126582278481, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=31.9526627218935, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081974, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=34.3023255813954, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787802, Length=86, Percent_Identity=38.3720930232558, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003018 [H]

Pfam domain/function: PF01590 GAF; PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 36747; Mature: 36747

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELILERLSESVATAENLEQLTRPLLEMLELITGLESLYLTSIDEEAGLQSVDFVRNAGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHCCCC
LVIPEGLSVPWSDTLCKRCLEEGRRYTSNASEIWGDSQAARALGIETYASAPIRASDGEI
EECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCE
IGTLCGASKRSQPLGPQAFSALNIFSKLIGHHIERERLLEELRRSNEYLANFALTDALTG
EEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPNRRALHGELGRLLARATRDESHVVVGIIDLDDFKRINDSYGHVVGDQFLSECSKRLSG
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVRDTDMLARVGGDEFALVAPCPASATQAHSLADQLQKRALAATRGVYTLADVTIDYAGV
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
SAGVVAVRPVSVEQALELADAAMYREKRQRKQSGPNGG
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MELILERLSESVATAENLEQLTRPLLEMLELITGLESLYLTSIDEEAGLQSVDFVRNAGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHCCCC
LVIPEGLSVPWSDTLCKRCLEEGRRYTSNASEIWGDSQAARALGIETYASAPIRASDGEI
EECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCE
IGTLCGASKRSQPLGPQAFSALNIFSKLIGHHIERERLLEELRRSNEYLANFALTDALTG
EEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPNRRALHGELGRLLARATRDESHVVVGIIDLDDFKRINDSYGHVVGDQFLSECSKRLSG
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVRDTDMLARVGGDEFALVAPCPASATQAHSLADQLQKRALAATRGVYTLADVTIDYAGV
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
SAGVVAVRPVSVEQALELADAAMYREKRQRKQSGPNGG
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]