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The map label for this gene is yjcC [H]

Identifier: 94312656

GI number: 94312656

Start: 265504

End: 267114

Strand: Direct

Name: yjcC [H]

Synonym: Rmet_3724

Alternate gene names: 94312656

Gene position: 265504-267114 (Clockwise)

Preceding gene: 94312654

Following gene: 94312657

Centisome position: 10.29

GC content: 62.07

Gene sequence:

>1611_bases
ATGAGGGGGCTGATAACAAGGATCGTGACCTATGCGGCGCTTGCACTAGCCTTCATGCTTCCCGTCTGTGCCTCTGTCTG
GATGAGTTACCGCCTCGCGCTGAGCGAGCAGCAGCTGCACACCGGCATCCTTGCTGCGGAGGTCCTGTACCGGGTCCACG
TCTTCAGCGAGCAGAACTTGCGTATCAATGCGGCCCTGAGGCGGCATGGCGCCACATCTCCATGTTCCCCGGACAACGTT
GCGCTGATGCGCAACCTCGCCGTCGGCGCAAGCTATCTGCAGGTGGTGGGCTATGTCGAAGGCAACGTGCTGCAATGCTC
GTCCTACGGGTACGGAGACGGGGACGCGGGTATCCCGATCGGTCCGCCAGCCTACCGAAGCCGTCTTGGCAATTGGGTGC
GGACGTCCGTGAAGTTGCCGTTCGATGAGAGCCGGCGATACATTGCGCTGACTGACTCGGTCACCGGCTATTCGAGCTTG
GCGCTGCCGGACATGCTTCTCGACACCGGCGGCGGCGGTCACGGCTTCGCGATCGCGCTGGTCGCCATTTCCAACAGACA
GATCGTCGTGCAACGCGACCCGATAGACCTTGGCGGCATGCCGCCACTGATTCGGGAACGCGGCACAATCACGTGGCAGC
ACCGTGGCGCCACGGGGTCGGTCAGCCTCTCTCCCTCGCGTGACTATGCAGCTGTCGTGATGTCCCCGGCCAGCGCGCTC
CACGCCAACTGGCGGAATGTCGCGACGTGGCTGGTACCGTTCGGCGCGTTGCTCGGCGGTGCGCTCGTGGCGCTCGCGCG
CCTGGGGCTGCGTCGGCGGCATGGGTTGCTGCGGCAGCTTGATCGCGCACTACGTGACGATGAACTGTCCCTCGCGTACA
TGCCGATTGTCGAACTGGAAAGCGGGAAATGGATCGGCGCCGAAGCGTTGATGCGCTGGTGCCACGACGGGCAGTGGATC
GCGCCCGACAAGTTCATCCCGCTGGCGGAGCGGCATCACCGCATCAGGAAGCTCACGAACAGAATGCTCGATCTGCTCGT
CGCCGACGCACAGGCGTTACCGCGGGACCTTGCCCGTGCGATGTACTTCTCGGTCAATCTGTCTGCGGAGGATCTGGCCG
CTTGCGCGATCGCGCAACGCGTTGCCGATGTCAGGCAAGCGTGTGGCGTTGACGGCGTGATGGTCGAAGCCACCGAAGGT
GTGCTGCTCGAAGCCAGCCGCGTCATCCCGAACATCGAGCGGTTACGCAAGCTTGGCATCCGCGTGGCGATCGATGATTT
CGGCACGGGCTACTCGTCACTCTCGTACCTTGGCTCACTGGACGTGGACTACATCAAGATCGACAAATCGTTCGTGTCGG
CCATCGGCACGAACTCGGTCAGGGGGCATGTCGTGGCGCACATCATCGACATGGCGAAGGACGTCGGCGTCGCGGTGATT
GCCGAAGGTGTGGAGACCCAGGAACAGGCGGACTATCTCATGGCGCGCGGCGTGCGATACGCGCAAGGGTGGTTGTTTGG
CAAGGCGATGCCGATGCAGGATTTCGTTTCCGCCATTAGGATGCATAATTTGTATTACAAAAATTGTATGCAAAAGCGAC
AGGTTCTGTGA

Upstream 100 bases:

>100_bases
GTCATGTCCCGAGCCGTCAAGCTATTGTCCCCAGTGGTTAAGCGTCGAACCGCCGTAGTGCATAGATTGATCGGCTCAAA
AAAAACGAATCGAGGTGCGG

Downstream 100 bases:

>100_bases
TAAAAACCCGAGGACAAATTCGGCTATGACCGGATCAACCGAGGAGACCCTGAAGCATGGAGACGTTGCTTTATAAGGTC
GAGGATCGTCCACCGATCCT

Product: EAL-containing signal transduction protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MRGLITRIVTYAALALAFMLPVCASVWMSYRLALSEQQLHTGILAAEVLYRVHVFSEQNLRINAALRRHGATSPCSPDNV
ALMRNLAVGASYLQVVGYVEGNVLQCSSYGYGDGDAGIPIGPPAYRSRLGNWVRTSVKLPFDESRRYIALTDSVTGYSSL
ALPDMLLDTGGGGHGFAIALVAISNRQIVVQRDPIDLGGMPPLIRERGTITWQHRGATGSVSLSPSRDYAAVVMSPASAL
HANWRNVATWLVPFGALLGGALVALARLGLRRRHGLLRQLDRALRDDELSLAYMPIVELESGKWIGAEALMRWCHDGQWI
APDKFIPLAERHHRIRKLTNRMLDLLVADAQALPRDLARAMYFSVNLSAEDLAACAIAQRVADVRQACGVDGVMVEATEG
VLLEASRVIPNIERLRKLGIRVAIDDFGTGYSSLSYLGSLDVDYIKIDKSFVSAIGTNSVRGHVVAHIIDMAKDVGVAVI
AEGVETQEQADYLMARGVRYAQGWLFGKAMPMQDFVSAIRMHNLYYKNCMQKRQVL

Sequences:

>Translated_536_residues
MRGLITRIVTYAALALAFMLPVCASVWMSYRLALSEQQLHTGILAAEVLYRVHVFSEQNLRINAALRRHGATSPCSPDNV
ALMRNLAVGASYLQVVGYVEGNVLQCSSYGYGDGDAGIPIGPPAYRSRLGNWVRTSVKLPFDESRRYIALTDSVTGYSSL
ALPDMLLDTGGGGHGFAIALVAISNRQIVVQRDPIDLGGMPPLIRERGTITWQHRGATGSVSLSPSRDYAAVVMSPASAL
HANWRNVATWLVPFGALLGGALVALARLGLRRRHGLLRQLDRALRDDELSLAYMPIVELESGKWIGAEALMRWCHDGQWI
APDKFIPLAERHHRIRKLTNRMLDLLVADAQALPRDLARAMYFSVNLSAEDLAACAIAQRVADVRQACGVDGVMVEATEG
VLLEASRVIPNIERLRKLGIRVAIDDFGTGYSSLSYLGSLDVDYIKIDKSFVSAIGTNSVRGHVVAHIIDMAKDVGVAVI
AEGVETQEQADYLMARGVRYAQGWLFGKAMPMQDFVSAIRMHNLYYKNCMQKRQVL
>Mature_536_residues
MRGLITRIVTYAALALAFMLPVCASVWMSYRLALSEQQLHTGILAAEVLYRVHVFSEQNLRINAALRRHGATSPCSPDNV
ALMRNLAVGASYLQVVGYVEGNVLQCSSYGYGDGDAGIPIGPPAYRSRLGNWVRTSVKLPFDESRRYIALTDSVTGYSSL
ALPDMLLDTGGGGHGFAIALVAISNRQIVVQRDPIDLGGMPPLIRERGTITWQHRGATGSVSLSPSRDYAAVVMSPASAL
HANWRNVATWLVPFGALLGGALVALARLGLRRRHGLLRQLDRALRDDELSLAYMPIVELESGKWIGAEALMRWCHDGQWI
APDKFIPLAERHHRIRKLTNRMLDLLVADAQALPRDLARAMYFSVNLSAEDLAACAIAQRVADVRQACGVDGVMVEATEG
VLLEASRVIPNIERLRKLGIRVAIDDFGTGYSSLSYLGSLDVDYIKIDKSFVSAIGTNSVRGHVVAHIIDMAKDVGVAVI
AEGVETQEQADYLMARGVRYAQGWLFGKAMPMQDFVSAIRMHNLYYKNCMQKRQVL

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=514, Percent_Identity=31.7120622568093, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87081743, Length=529, Percent_Identity=30.0567107750473, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1788502, Length=277, Percent_Identity=32.129963898917, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081980, Length=257, Percent_Identity=35.0194552529183, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786507, Length=246, Percent_Identity=34.9593495934959, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081845, Length=278, Percent_Identity=32.0143884892086, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87081921, Length=245, Percent_Identity=35.1020408163265, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=37.1900826446281, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=34.297520661157, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1787541, Length=244, Percent_Identity=36.0655737704918, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI226510982, Length=247, Percent_Identity=33.6032388663968, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788849, Length=259, Percent_Identity=28.1853281853282, Blast_Score=106, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58758; Mature: 58758

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLITRIVTYAALALAFMLPVCASVWMSYRLALSEQQLHTGILAAEVLYRVHVFSEQNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCE
RINAALRRHGATSPCSPDNVALMRNLAVGASYLQVVGYVEGNVLQCSSYGYGDGDAGIPI
EEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
GPPAYRSRLGNWVRTSVKLPFDESRRYIALTDSVTGYSSLALPDMLLDTGGGGHGFAIAL
CCHHHHHHCCHHHHHEEECCCCCCCCEEEEECCCCCCCHHCCCHHHHCCCCCCCCEEEEE
VAISNRQIVVQRDPIDLGGMPPLIRERGTITWQHRGATGSVSLSPSRDYAAVVMSPASAL
EEECCCEEEEEECCCCCCCCCHHHHCCCCEEEEECCCCCEEEECCCCCCEEEEECCHHHH
HANWRNVATWLVPFGALLGGALVALARLGLRRRHGLLRQLDRALRDDELSLAYMPIVELE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEC
SGKWIGAEALMRWCHDGQWIAPDKFIPLAERHHRIRKLTNRMLDLLVADAQALPRDLARA
CCCEECHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYFSVNLSAEDLAACAIAQRVADVRQACGVDGVMVEATEGVLLEASRVIPNIERLRKLGI
HHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHCCCHHHHHHCCC
RVAIDDFGTGYSSLSYLGSLDVDYIKIDKSFVSAIGTNSVRGHVVAHIIDMAKDVGVAVI
EEEEECCCCCHHHHHHHCCCCCEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEE
AEGVETQEQADYLMARGVRYAQGWLFGKAMPMQDFVSAIRMHNLYYKNCMQKRQVL
ECCCCHHHHHHHHHHCCCHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRGLITRIVTYAALALAFMLPVCASVWMSYRLALSEQQLHTGILAAEVLYRVHVFSEQNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCE
RINAALRRHGATSPCSPDNVALMRNLAVGASYLQVVGYVEGNVLQCSSYGYGDGDAGIPI
EEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
GPPAYRSRLGNWVRTSVKLPFDESRRYIALTDSVTGYSSLALPDMLLDTGGGGHGFAIAL
CCHHHHHHCCHHHHHEEECCCCCCCCEEEEECCCCCCCHHCCCHHHHCCCCCCCCEEEEE
VAISNRQIVVQRDPIDLGGMPPLIRERGTITWQHRGATGSVSLSPSRDYAAVVMSPASAL
EEECCCEEEEEECCCCCCCCCHHHHCCCCEEEEECCCCCEEEECCCCCCEEEEECCHHHH
HANWRNVATWLVPFGALLGGALVALARLGLRRRHGLLRQLDRALRDDELSLAYMPIVELE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEC
SGKWIGAEALMRWCHDGQWIAPDKFIPLAERHHRIRKLTNRMLDLLVADAQALPRDLARA
CCCEECHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYFSVNLSAEDLAACAIAQRVADVRQACGVDGVMVEATEGVLLEASRVIPNIERLRKLGI
HHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHCCCHHHHHHCCC
RVAIDDFGTGYSSLSYLGSLDVDYIKIDKSFVSAIGTNSVRGHVVAHIIDMAKDVGVAVI
EEEEECCCCCHHHHHHHCCCCCEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEE
AEGVETQEQADYLMARGVRYAQGWLFGKAMPMQDFVSAIRMHNLYYKNCMQKRQVL
ECCCCHHHHHHHHHHCCCHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]