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The map label for this gene is lldP [C]

Identifier: 93006712

GI number: 93006712

Start: 2332564

End: 2334321

Strand: Direct

Name: lldP [C]

Synonym: Pcryo_1888

Alternate gene names: 93006712

Gene position: 2332564-2334321 (Clockwise)

Preceding gene: 93006711

Following gene: 93006713

Centisome position: 76.23

GC content: 45.34

Gene sequence:

>1758_bases
ATGTACACTTTTTTGGCCTTAGCGCCTATTCTGGTAGTACTCGTTTTGCTTGTAATGTTGCGGCTCCCTGCCAAGATTTC
TATGGGCGTTGCCTATTTAGTAACCGCGCTATTAGCGTTGTTCGTTTGGCAAGCCAGTGGCGCCCAAGTCGCAGCCGCGA
CTGTAAACGGCATCATCGTCGCACTCACGCTTTTATTTATTGTATTTGCGGCTATTTTATTGCTGAATACTTTGAAGGAA
GGGGGCGCTATTGTCGCTATTCGTAAAGGCTTTATGGATATCTCGCCCGATAGACGCGTTCAAGTTATCATTGTGGCGTG
GTTATTCGGCTCGCTGATAGAAGGCTCATCAGGATTTGGTACGCCATCTGCTATCGGTGCACCGTTGTTGTTGGCTTTAG
GTTTCCCAGCGATGGCATCAGTTATGGCTATGTTAATTATTCAGTCGACGCCCGTATCATTTGGTGCCGTTGGTACGCCA
GTATTACTTGGCGTTTGGACTGGTATCAATGATAAGCCAGATATAACGCAAGCGATTGCGCCACTCTCAACTGAAAACTA
TCTATTACAAATCGCGGGTAACATCGGTCTGATACATGCGCTGGTGGGTTTTCTAATTCCGTTACTTTTGAGTGGATTTT
TGACTCGGTTCTTTGGTAAAAATCGCTCCTTCGTTGAAGGGCTCAAAGTATGGCCTTTTGCAATTTTTGCTGGTCTCTGC
TTTACCGTTCCTTATTATTTAGTGGCTAGATACCTAGGTCCTGAGTTCCCATCATTGGTCGGCGGTTTTATCGGTCTTAT
GATTGTGCTTCCTGCAGCAAAGCGCGGCTTCTTGATGCCTAAAGAGATTTTTGATTTTGCGCCACGCGCTAAATGGGATA
AAGACTGGCTAGGCTCGTTACCTGAAGAAAAGTTTGATGATTCCATTGCACCAAGATTTTCTTTGGTTCGGGCATTTTCT
CCTTATCTCATCGTTATTGGTCTACTAATCATCACTCGAGTCATTGCACCACTGAAGGCATTTTTGACTGGAGATTTGAC
CACTATACAATTTACCAATCTTTTTGGTACAACTATTTCTAGTAAAATCCAACTTGCCTATTCTCCAGGTATCATTCTAA
TTATTGTTGCCTTAATCTCTATCTTGTTGTTCAAAATGAACGGACAAGCCGTCAAACGTAGTTGGAGTAGTTCTGCAAAA
ACCATGGTAGCCGCCGCACCAGCCTTGCTGTTTTCGGTACCGATGGTACAAGTATTCATCAACTCCGGGTCAGCTGCTGA
AGTCGCAAATTCGCTACCCGCTATGCCCATCTTACTGGCTGAGAGTGCCGCTGGTGCATTTCAAAATGCATGGCCACTCG
TGTCTCCGTGGATTGGCGCGCTGGGTGCGTTCATTGCAGGCTCAAATACCGTCAGTAATATGATGTTCGCTTACTTTCAG
TGGTCAACCGCCAGTCAAATTGGCTTAGATGTCAATCTTGCTGCACAAGTAGTAGCACTGCAAGCGGTCGGTGGCGCAGC
GGGTAATATGATTGCGGTACATAACGTCGTTGCTGCTTGCGCGGTGGTTGGTCTAATGGATAAAGAAGGCTATGTTATTC
GCAAAACCTTAGTCGCAATGACATACTATGTGATTCAGGCAGGATTGATCGGTATGGGTATTATTTTCGGTCAAATGTGG
TGGTGGATATTGGCTGTCATTTGGCCAATCGCATTTTTTGGCATCATGGCAATGACGAGTAAAAAAACCGTTGCTTAA

Upstream 100 bases:

>100_bases
TACGGGCTTCTTTTGGCTTAATACTGATAAACAAAAAAGAAATATCATTCAATGATATTTCAAAGATGACTTCAACTACA
TATACCAAGGACGGTTTATT

Downstream 100 bases:

>100_bases
CATGAGTTAGCTGTACTAGTAAATCTGTGAATCTGCACTCAGTACTTGAACTGACGCTATTATACTAACTATGATAGCGT
CAGTTTTATGTCACGGTTAA

Product: L-lactate transport

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MYTFLALAPILVVLVLLVMLRLPAKISMGVAYLVTALLALFVWQASGAQVAAATVNGIIVALTLLFIVFAAILLLNTLKE
GGAIVAIRKGFMDISPDRRVQVIIVAWLFGSLIEGSSGFGTPSAIGAPLLLALGFPAMASVMAMLIIQSTPVSFGAVGTP
VLLGVWTGINDKPDITQAIAPLSTENYLLQIAGNIGLIHALVGFLIPLLLSGFLTRFFGKNRSFVEGLKVWPFAIFAGLC
FTVPYYLVARYLGPEFPSLVGGFIGLMIVLPAAKRGFLMPKEIFDFAPRAKWDKDWLGSLPEEKFDDSIAPRFSLVRAFS
PYLIVIGLLIITRVIAPLKAFLTGDLTTIQFTNLFGTTISSKIQLAYSPGIILIIVALISILLFKMNGQAVKRSWSSSAK
TMVAAAPALLFSVPMVQVFINSGSAAEVANSLPAMPILLAESAAGAFQNAWPLVSPWIGALGAFIAGSNTVSNMMFAYFQ
WSTASQIGLDVNLAAQVVALQAVGGAAGNMIAVHNVVAACAVVGLMDKEGYVIRKTLVAMTYYVIQAGLIGMGIIFGQMW
WWILAVIWPIAFFGIMAMTSKKTVA

Sequences:

>Translated_585_residues
MYTFLALAPILVVLVLLVMLRLPAKISMGVAYLVTALLALFVWQASGAQVAAATVNGIIVALTLLFIVFAAILLLNTLKE
GGAIVAIRKGFMDISPDRRVQVIIVAWLFGSLIEGSSGFGTPSAIGAPLLLALGFPAMASVMAMLIIQSTPVSFGAVGTP
VLLGVWTGINDKPDITQAIAPLSTENYLLQIAGNIGLIHALVGFLIPLLLSGFLTRFFGKNRSFVEGLKVWPFAIFAGLC
FTVPYYLVARYLGPEFPSLVGGFIGLMIVLPAAKRGFLMPKEIFDFAPRAKWDKDWLGSLPEEKFDDSIAPRFSLVRAFS
PYLIVIGLLIITRVIAPLKAFLTGDLTTIQFTNLFGTTISSKIQLAYSPGIILIIVALISILLFKMNGQAVKRSWSSSAK
TMVAAAPALLFSVPMVQVFINSGSAAEVANSLPAMPILLAESAAGAFQNAWPLVSPWIGALGAFIAGSNTVSNMMFAYFQ
WSTASQIGLDVNLAAQVVALQAVGGAAGNMIAVHNVVAACAVVGLMDKEGYVIRKTLVAMTYYVIQAGLIGMGIIFGQMW
WWILAVIWPIAFFGIMAMTSKKTVA
>Mature_585_residues
MYTFLALAPILVVLVLLVMLRLPAKISMGVAYLVTALLALFVWQASGAQVAAATVNGIIVALTLLFIVFAAILLLNTLKE
GGAIVAIRKGFMDISPDRRVQVIIVAWLFGSLIEGSSGFGTPSAIGAPLLLALGFPAMASVMAMLIIQSTPVSFGAVGTP
VLLGVWTGINDKPDITQAIAPLSTENYLLQIAGNIGLIHALVGFLIPLLLSGFLTRFFGKNRSFVEGLKVWPFAIFAGLC
FTVPYYLVARYLGPEFPSLVGGFIGLMIVLPAAKRGFLMPKEIFDFAPRAKWDKDWLGSLPEEKFDDSIAPRFSLVRAFS
PYLIVIGLLIITRVIAPLKAFLTGDLTTIQFTNLFGTTISSKIQLAYSPGIILIIVALISILLFKMNGQAVKRSWSSSAK
TMVAAAPALLFSVPMVQVFINSGSAAEVANSLPAMPILLAESAAGAFQNAWPLVSPWIGALGAFIAGSNTVSNMMFAYFQ
WSTASQIGLDVNLAAQVVALQAVGGAAGNMIAVHNVVAACAVVGLMDKEGYVIRKTLVAMTYYVIQAGLIGMGIIFGQMW
WWILAVIWPIAFFGIMAMTSKKTVA

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=575, Percent_Identity=27.304347826087, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789347, Length=265, Percent_Identity=29.0566037735849, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 62368; Mature: 62368

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTFLALAPILVVLVLLVMLRLPAKISMGVAYLVTALLALFVWQASGAQVAAATVNGIIV
CCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
ALTLLFIVFAAILLLNTLKEGGAIVAIRKGFMDISPDRRVQVIIVAWLFGSLIEGSSGFG
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCC
TPSAIGAPLLLALGFPAMASVMAMLIIQSTPVSFGAVGTPVLLGVWTGINDKPDITQAIA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCHHHHHC
PLSTENYLLQIAGNIGLIHALVGFLIPLLLSGFLTRFFGKNRSFVEGLKVWPFAIFAGLC
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FTVPYYLVARYLGPEFPSLVGGFIGLMIVLPAAKRGFLMPKEIFDFAPRAKWDKDWLGSL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHCCC
PEEKFDDSIAPRFSLVRAFSPYLIVIGLLIITRVIAPLKAFLTGDLTTIQFTNLFGTTIS
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHC
SKIQLAYSPGIILIIVALISILLFKMNGQAVKRSWSSSAKTMVAAAPALLFSVPMVQVFI
CCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSGSAAEVANSLPAMPILLAESAAGAFQNAWPLVSPWIGALGAFIAGSNTVSNMMFAYFQ
CCCCHHHHHHCCCCCHHEEEHHHCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
WSTASQIGLDVNLAAQVVALQAVGGAAGNMIAVHNVVAACAVVGLMDKEGYVIRKTLVAM
CCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TYYVIQAGLIGMGIIFGQMWWWILAVIWPIAFFGIMAMTSKKTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYTFLALAPILVVLVLLVMLRLPAKISMGVAYLVTALLALFVWQASGAQVAAATVNGIIV
CCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
ALTLLFIVFAAILLLNTLKEGGAIVAIRKGFMDISPDRRVQVIIVAWLFGSLIEGSSGFG
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCC
TPSAIGAPLLLALGFPAMASVMAMLIIQSTPVSFGAVGTPVLLGVWTGINDKPDITQAIA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCHHHHHC
PLSTENYLLQIAGNIGLIHALVGFLIPLLLSGFLTRFFGKNRSFVEGLKVWPFAIFAGLC
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FTVPYYLVARYLGPEFPSLVGGFIGLMIVLPAAKRGFLMPKEIFDFAPRAKWDKDWLGSL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHCCC
PEEKFDDSIAPRFSLVRAFSPYLIVIGLLIITRVIAPLKAFLTGDLTTIQFTNLFGTTIS
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHC
SKIQLAYSPGIILIIVALISILLFKMNGQAVKRSWSSSAKTMVAAAPALLFSVPMVQVFI
CCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSGSAAEVANSLPAMPILLAESAAGAFQNAWPLVSPWIGALGAFIAGSNTVSNMMFAYFQ
CCCCHHHHHHCCCCCHHEEEHHHCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
WSTASQIGLDVNLAAQVVALQAVGGAAGNMIAVHNVVAACAVVGLMDKEGYVIRKTLVAM
CCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TYYVIQAGLIGMGIIFGQMWWWILAVIWPIAFFGIMAMTSKKTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]