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The map label for this gene is asd [H]

Identifier: 93006525

GI number: 93006525

Start: 2105494

End: 2106627

Strand: Direct

Name: asd [H]

Synonym: Pcryo_1701

Alternate gene names: 93006525

Gene position: 2105494-2106627 (Clockwise)

Preceding gene: 93006523

Following gene: 93006527

Centisome position: 68.81

GC content: 45.33

Gene sequence:

>1134_bases
ATGAGTGATTTAACAGTAGGTTTGGTAGGCTGGCGCGGTATGGTCGGGTCAGTATTGTTACAACGTATGATGGAAGAAAA
AGATTTTGACGGTATTACGCCAGTATTCTTTTCAACCAGTAATGCAGGCGGTGATGCGCCAAGTTTTGATGGTATTAAGA
CCAGCCAACTACAAGATGCTCATGATATTGACGCCCTTACCGCTTGTGATGTGATTATTACCTGCCAAGGTGGCGACTAT
ACCTCAAAAGTACATCAACCACTGCGGGATAGTGGTTGGGCTGGTTATTGGATTGATGCGGCAAGTACCTTACGCATGGA
AGATGACAGCATCATCATTCTTGATCCGGTTAATCGAGTTGTTATCGATAATGCACTCGCTGAGGGTAAAAAAGACTTTA
TCGGTGGCAACTGTACTGTGTCACTAATGCTGATGGCAATTGGTGAGCTGTTTAATAAAGGTTGGGTAGAATGGGTCAGC
GCCATGACTTATCAAGCCGCTAGTGGTTCAGGCGCTAACAACATGCGTGAGCTTATTGAAGGCATGGGTGTATTACGTGA
TGCTGTTAAAGATGAGCTTGCCAATCCTGCTAGCGCCATTCTTGAGATTGATAAAAAAATCGCTCAGACTCAACGCTCAG
ACGATTTTCCTAAACAATACTTTGGCGTGCCATTGGCCGGTAGCTTGATTCCTTATATCGACTCACAATTAGAGAACAAG
CAGTCTCGTGAAGAATGGAAAGGTGGTGTTGAAACCAATAAGATCCTTGGCAACTCTGAAGCAGATAAGATTGCTATCGA
TGGTATGTGTGTTCGCGTTGGGGCGATGCGCTGTCATGCACAAGGCTTAACGATTAAGCTCAAAAAAGACATTCCACTAA
AAGAGATTGAAGCAGCACTGAAGAATAGCGGTAATCAGTGGTTAGACGTGGTTGAAGACAATAAAGAAGCCACTATGAAC
CGCTTAACACCTGTTGCAGTAACCGGCACCTTAACGGTTGCACTAGGTCGCCTGCGTAAGCTTAATATGGGGCCTGAGTA
TTTAGGCGCATTCACCGTTGGTGACCAACTATTATGGGGCGCGGCTGAGCCATTACGCCGTATGCTGAACATCATTCGCG
AGCAAAATAGCTGA

Upstream 100 bases:

>100_bases
ACCCGCGAAACCCATCAAAAAACCTTGCTTTTTGGAGCTATTCACGGCATTGTTATTGGTTGGCGATGCAACAATTTATT
GTAAAAAAGGATTGAGTTTG

Downstream 100 bases:

>100_bases
AGCTAATATTCTGAATTTGGATATAAAAAAGACAGCAATTGCTGTCTTTTTTATGAGTTATTTTTGCTGATAAGTGATCA
TTATTTCATTGCGGCGCATA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSDLTVGLVGWRGMVGSVLLQRMMEEKDFDGITPVFFSTSNAGGDAPSFDGIKTSQLQDAHDIDALTACDVIITCQGGDY
TSKVHQPLRDSGWAGYWIDAASTLRMEDDSIIILDPVNRVVIDNALAEGKKDFIGGNCTVSLMLMAIGELFNKGWVEWVS
AMTYQAASGSGANNMRELIEGMGVLRDAVKDELANPASAILEIDKKIAQTQRSDDFPKQYFGVPLAGSLIPYIDSQLENK
QSREEWKGGVETNKILGNSEADKIAIDGMCVRVGAMRCHAQGLTIKLKKDIPLKEIEAALKNSGNQWLDVVEDNKEATMN
RLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWGAAEPLRRMLNIIREQNS

Sequences:

>Translated_377_residues
MSDLTVGLVGWRGMVGSVLLQRMMEEKDFDGITPVFFSTSNAGGDAPSFDGIKTSQLQDAHDIDALTACDVIITCQGGDY
TSKVHQPLRDSGWAGYWIDAASTLRMEDDSIIILDPVNRVVIDNALAEGKKDFIGGNCTVSLMLMAIGELFNKGWVEWVS
AMTYQAASGSGANNMRELIEGMGVLRDAVKDELANPASAILEIDKKIAQTQRSDDFPKQYFGVPLAGSLIPYIDSQLENK
QSREEWKGGVETNKILGNSEADKIAIDGMCVRVGAMRCHAQGLTIKLKKDIPLKEIEAALKNSGNQWLDVVEDNKEATMN
RLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWGAAEPLRRMLNIIREQNS
>Mature_376_residues
SDLTVGLVGWRGMVGSVLLQRMMEEKDFDGITPVFFSTSNAGGDAPSFDGIKTSQLQDAHDIDALTACDVIITCQGGDYT
SKVHQPLRDSGWAGYWIDAASTLRMEDDSIIILDPVNRVVIDNALAEGKKDFIGGNCTVSLMLMAIGELFNKGWVEWVSA
MTYQAASGSGANNMRELIEGMGVLRDAVKDELANPASAILEIDKKIAQTQRSDDFPKQYFGVPLAGSLIPYIDSQLENKQ
SREEWKGGVETNKILGNSEADKIAIDGMCVRVGAMRCHAQGLTIKLKKDIPLKEIEAALKNSGNQWLDVVEDNKEATMNR
LTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWGAAEPLRRMLNIIREQNS

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=364, Percent_Identity=64.5604395604396, Blast_Score=481, Evalue=1e-137,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 41103; Mature: 40972

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLTVGLVGWRGMVGSVLLQRMMEEKDFDGITPVFFSTSNAGGDAPSFDGIKTSQLQDA
CCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCH
HDIDALTACDVIITCQGGDYTSKVHQPLRDSGWAGYWIDAASTLRMEDDSIIILDPVNRV
HHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCEEEECCCCHH
VIDNALAEGKKDFIGGNCTVSLMLMAIGELFNKGWVEWVSAMTYQAASGSGANNMRELIE
HHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GMGVLRDAVKDELANPASAILEIDKKIAQTQRSDDFPKQYFGVPLAGSLIPYIDSQLENK
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
QSREEWKGGVETNKILGNSEADKIAIDGMCVRVGAMRCHAQGLTIKLKKDIPLKEIEAAL
HHHHHHCCCCCHHHCCCCCCCCEEEECCEEEHHHHHHEECCCCEEEEECCCCHHHHHHHH
KNSGNQWLDVVEDNKEATMNRLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWG
HCCCCCEEHEEECCHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHC
AAEPLRRMLNIIREQNS
CHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDLTVGLVGWRGMVGSVLLQRMMEEKDFDGITPVFFSTSNAGGDAPSFDGIKTSQLQDA
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCH
HDIDALTACDVIITCQGGDYTSKVHQPLRDSGWAGYWIDAASTLRMEDDSIIILDPVNRV
HHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCEEEECCCCHH
VIDNALAEGKKDFIGGNCTVSLMLMAIGELFNKGWVEWVSAMTYQAASGSGANNMRELIE
HHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GMGVLRDAVKDELANPASAILEIDKKIAQTQRSDDFPKQYFGVPLAGSLIPYIDSQLENK
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
QSREEWKGGVETNKILGNSEADKIAIDGMCVRVGAMRCHAQGLTIKLKKDIPLKEIEAAL
HHHHHHCCCCCHHHCCCCCCCCEEEECCEEEHHHHHHEECCCCEEEEECCCCHHHHHHHH
KNSGNQWLDVVEDNKEATMNRLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWG
HCCCCCEEHEEECCHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHC
AAEPLRRMLNIIREQNS
CHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9084174; 10984043 [H]