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The map label for this gene is surA [H]

Identifier: 93006523

GI number: 93006523

Start: 2101993

End: 2103390

Strand: Direct

Name: surA [H]

Synonym: Pcryo_1699

Alternate gene names: 93006523

Gene position: 2101993-2103390 (Clockwise)

Preceding gene: 93006522

Following gene: 93006525

Centisome position: 68.7

GC content: 45.49

Gene sequence:

>1398_bases
ATGAGATTTTTTTCTTTACGCCAAACAAGCCAAGCAGTATTCCTATCGATGGGCTTAATGACTGCTCTTGGTATGAGCGT
TAGTGCCCAAGCAGCAACGGTGAACTCTGCAAAAGCGCAAGCGACGACAACTCAAAAAAACAACGTGGCCCGTTTAACGC
CTGCCAATAGTACAGATGGCATAATTGCATTGGTGAATGAAAATGCGATTTTAAAAAGTGATCTCATTGCTGCCATTGCT
CAGACACAGGCACGTGCAAAAGCGGCGGGTGAACCTATTGCCAATTCAGCACAGTTACAGTCAGAAGTATTAAACGCCCT
TATTTTGCGCGAACTACAGCTGTCCTTGATCAAACGTGTTGGTTTAAATCCCGATGAAGCGTCTATCAATAAGCGCTTAG
AACAAATAGCAAAAGCAGAAGGTTTAAATAGCATCGCCGCTTTACAACAGCGTTTAGACTCAGCGCAATCGGGCAGCTAC
GCGACTTTGCGCGCGCAGTTGATTGAAGATGCCGCTATTCAAGCCTTACAACAGCGTCAAATCACCAATCGTGTGCGTAT
TAGCGAGCAGGATATTGATGCATTTTTGGCATCACCTGAAGCCAAACGCTTGAACCAAAGTGAGTATCAGACAGTCCATG
TCCGTGTTCCATATATGGATGACTATAGTCGCCTATCAGAAGCACAGCGTAATGACGCTTTAAAAGTGGCACAAAAGTTA
CGTACACGCCTTCTTGTGCCAAATGTCAATGTCGCTGAAGCGATTGCAGCCAGTCAAGGCAGCTACCCTATCCCATTACA
AGGTGGTGATATGGGCTTTCATAAAGCCGCTGCCCTCCCAACTGAGCTATCGAGCGAGATTACCAAACTTGAGGTTGGCG
CTGTGAGTGCGCCTTTAGTCACCCCTGAAGGTATCGATATTATTAAGCTTGCCAATAAAAAAGCCAATGATACCATGCTT
GTTCCTCAGTGGAATACTCGTCATATCTTGGTTAAAGTTGATGAGCTACAAACAGATGCTCTTGCTGAGCAAAAAATTAA
CGACCTATATAGTCAGCTACGTAATGGTGCTGCCTTTGATAGTCTAGCATCAACGTATTCAGACGATCCTGGTTCAGCAG
GGCGCGGCGGCGATTTAGATTGGGTTGGTGAAGATCAAATGATTGCTCCGTTTGAAGCAATGATGAAAAACACAGCTGTC
GGTGACTATTCTGCCCCGTTTAAAACGCAATTTGGTTGGCACATACTCAAAGTTGAAGGTAAGCGTCAACAAGATGTCAG
CGATGAGTATCGTCGCACTATGGCACGTCAAGCTCTATATCAACGCCTAGCACCACAAGCCAAAGAAGACTGGCTACAAG
AGTTACGTGCTGGCGCTTATATCCAAGTGCTTGGTTAA

Upstream 100 bases:

>100_bases
CCTAGCTAATACTTTAGTATTAACATTATTTGATGCTAAAGCAGTGGCTAGTGGATTTAACCGATTACCATCCGATGCAA
TGACATTGATGAGGAGCATC

Downstream 100 bases:

>100_bases
TGATCAAGTGAACTAAATAACCAGTCAAAGTATTTTATAAAAAAGGGTATATGCCGGTGCGTATATCCTTTTTTTATGCC
TTTTGATTTGTTATTTACTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MRFFSLRQTSQAVFLSMGLMTALGMSVSAQAATVNSAKAQATTTQKNNVARLTPANSTDGIIALVNENAILKSDLIAAIA
QTQARAKAAGEPIANSAQLQSEVLNALILRELQLSLIKRVGLNPDEASINKRLEQIAKAEGLNSIAALQQRLDSAQSGSY
ATLRAQLIEDAAIQALQQRQITNRVRISEQDIDAFLASPEAKRLNQSEYQTVHVRVPYMDDYSRLSEAQRNDALKVAQKL
RTRLLVPNVNVAEAIAASQGSYPIPLQGGDMGFHKAAALPTELSSEITKLEVGAVSAPLVTPEGIDIIKLANKKANDTML
VPQWNTRHILVKVDELQTDALAEQKINDLYSQLRNGAAFDSLASTYSDDPGSAGRGGDLDWVGEDQMIAPFEAMMKNTAV
GDYSAPFKTQFGWHILKVEGKRQQDVSDEYRRTMARQALYQRLAPQAKEDWLQELRAGAYIQVLG

Sequences:

>Translated_465_residues
MRFFSLRQTSQAVFLSMGLMTALGMSVSAQAATVNSAKAQATTTQKNNVARLTPANSTDGIIALVNENAILKSDLIAAIA
QTQARAKAAGEPIANSAQLQSEVLNALILRELQLSLIKRVGLNPDEASINKRLEQIAKAEGLNSIAALQQRLDSAQSGSY
ATLRAQLIEDAAIQALQQRQITNRVRISEQDIDAFLASPEAKRLNQSEYQTVHVRVPYMDDYSRLSEAQRNDALKVAQKL
RTRLLVPNVNVAEAIAASQGSYPIPLQGGDMGFHKAAALPTELSSEITKLEVGAVSAPLVTPEGIDIIKLANKKANDTML
VPQWNTRHILVKVDELQTDALAEQKINDLYSQLRNGAAFDSLASTYSDDPGSAGRGGDLDWVGEDQMIAPFEAMMKNTAV
GDYSAPFKTQFGWHILKVEGKRQQDVSDEYRRTMARQALYQRLAPQAKEDWLQELRAGAYIQVLG
>Mature_465_residues
MRFFSLRQTSQAVFLSMGLMTALGMSVSAQAATVNSAKAQATTTQKNNVARLTPANSTDGIIALVNENAILKSDLIAAIA
QTQARAKAAGEPIANSAQLQSEVLNALILRELQLSLIKRVGLNPDEASINKRLEQIAKAEGLNSIAALQQRLDSAQSGSY
ATLRAQLIEDAAIQALQQRQITNRVRISEQDIDAFLASPEAKRLNQSEYQTVHVRVPYMDDYSRLSEAQRNDALKVAQKL
RTRLLVPNVNVAEAIAASQGSYPIPLQGGDMGFHKAAALPTELSSEITKLEVGAVSAPLVTPEGIDIIKLANKKANDTML
VPQWNTRHILVKVDELQTDALAEQKINDLYSQLRNGAAFDSLASTYSDDPGSAGRGGDLDWVGEDQMIAPFEAMMKNTAV
GDYSAPFKTQFGWHILKVEGKRQQDVSDEYRRTMARQALYQRLAPQAKEDWLQELRAGAYIQVLG

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=399, Percent_Identity=24.3107769423559, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 50743; Mature: 50743

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFSLRQTSQAVFLSMGLMTALGMSVSAQAATVNSAKAQATTTQKNNVARLTPANSTDG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHCCCCCCEEEECCCCCCCC
IIALVNENAILKSDLIAAIAQTQARAKAAGEPIANSAQLQSEVLNALILRELQLSLIKRV
EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLNPDEASINKRLEQIAKAEGLNSIAALQQRLDSAQSGSYATLRAQLIEDAAIQALQQRQ
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ITNRVRISEQDIDAFLASPEAKRLNQSEYQTVHVRVPYMDDYSRLSEAQRNDALKVAQKL
HHHHHHCCHHHHHHHHCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RTRLLVPNVNVAEAIAASQGSYPIPLQGGDMGFHKAAALPTELSSEITKLEVGAVSAPLV
HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHEEECCCCCCCC
TPEGIDIIKLANKKANDTMLVPQWNTRHILVKVDELQTDALAEQKINDLYSQLRNGAAFD
CCCCCCEEEECCCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHH
SLASTYSDDPGSAGRGGDLDWVGEDQMIAPFEAMMKNTAVGDYSAPFKTQFGWHILKVEG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
KRQQDVSDEYRRTMARQALYQRLAPQAKEDWLQELRAGAYIQVLG
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MRFFSLRQTSQAVFLSMGLMTALGMSVSAQAATVNSAKAQATTTQKNNVARLTPANSTDG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHCCCCCCEEEECCCCCCCC
IIALVNENAILKSDLIAAIAQTQARAKAAGEPIANSAQLQSEVLNALILRELQLSLIKRV
EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLNPDEASINKRLEQIAKAEGLNSIAALQQRLDSAQSGSYATLRAQLIEDAAIQALQQRQ
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ITNRVRISEQDIDAFLASPEAKRLNQSEYQTVHVRVPYMDDYSRLSEAQRNDALKVAQKL
HHHHHHCCHHHHHHHHCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RTRLLVPNVNVAEAIAASQGSYPIPLQGGDMGFHKAAALPTELSSEITKLEVGAVSAPLV
HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHEEECCCCCCCC
TPEGIDIIKLANKKANDTMLVPQWNTRHILVKVDELQTDALAEQKINDLYSQLRNGAAFD
CCCCCCEEEECCCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHH
SLASTYSDDPGSAGRGGDLDWVGEDQMIAPFEAMMKNTAVGDYSAPFKTQFGWHILKVEG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
KRQQDVSDEYRRTMARQALYQRLAPQAKEDWLQELRAGAYIQVLG
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA