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The map label for this gene is ydeP [H]

Identifier: 93006426

GI number: 93006426

Start: 1962970

End: 1965312

Strand: Direct

Name: ydeP [H]

Synonym: Pcryo_1602

Alternate gene names: 93006426

Gene position: 1962970-1965312 (Clockwise)

Preceding gene: 93006425

Following gene: 93006427

Centisome position: 64.15

GC content: 45.92

Gene sequence:

>2343_bases
ATGCGCAAAATTCCTGTTTATATACACCCTGCAGCGGGCTGGCCTGCACTGATTGCCTCTACGCGTACCTTAATGGATTA
CAAGGCTTTTTTGCGCGGCAGTATCAGCGTCTTACATAGCAATCAGCCAAAGGACGGCTTTGATTGTCCGGGCTGCGCAT
GGCCGGATCACAAGTCAAATAAGGCCATAGATGTCTGTGAAAACGGTATCAAAGTCATCGCCAGTGAAACGATGAACAGA
CGAGCAGACGCAACTTTTTTTGCTAATAATACAGTCACAGCGTTACAAGGCTGGTCAGGCTATGAGCTTGAACACAGTGG
ACGCTTATCAGAACCACTCTATTATTATGCTGCTCAAGACCGCTATCTGCCGATTTCTTGGCAAGCGGCTTATGAGATTA
TCGCTGACCAATTAAAACAGCTTGATTCGCCAGATGAAGCACTGTTTTATACCTCAGGACGGGTGACCAACGAGCCTGCT
TTTATGTTTCAACTATTTGTGCGCTGTTTTGGCACCAATAACTTGCCTGATTGCTCAAACATGTGTCATGAGCCAACGTC
AGTGATGCTTGGTAAGCAGTTAGGCATCGGTAAAGCAACCGTAATATTGGAAGATTTTGAGCAGGCTAAATTGATTTTAT
TGTTTGGACAAAATCCTGCAACCAATCACCCACGTATGCTTGAGATGCTCGCCCATGCCCATAAGCAAGGCTGCCGAATT
ATTTCTATCAACCCCATGCGTGAACAGGGTCTAAGCAAGTTTAGAAACCCACAAAAACCCTCCCATATGGCAGCAGGTCA
AAGTGATGAGATGGTCGATGAGGTTATCCAAATACAAATCGGTGGCGATGCGGCTTTATTAACCGGCATGGCCAAATGGC
TCACCAAAAACGGTAAAATGAACAGTGGTTTTATTGAGCAGCATACCTCAGGCTATGACGCTCTGGATGCTTGGTTACAT
CAGCAATCTTGGACGGATGTAGAGCTTGGCTGTGGCATTAGTAAAGCAGAGATTATTATGCTCGCAAAGTTGGTTGCTGA
GAGTCCAGCAACGATTTGTACATGGGGCATGGGCATCACTCAGCATGTCCAAGGCGAAGATAATGTTGCCATGATTACCA
ACTTGCTATTGTTGATGGGTATGATTGGTATCGATGGTGCAGGCGCATCGCCTGTACGTGGACACTCAAACGTGCAGGGT
GATCGTACCATGGGTATTCATGAACGCCCTAAGCAGAGCTTGCTTGATAGTCTTGAGCGTGTTTTTAAGCAACCGATGCC
ACAAGAAGATGGGCTTGATGTCATCGCCGGTGCAAAGGCACTAATAAAAGGCGACATCAAAGCCTTTGTTAGTATGGGTG
GCAACTATGCGGTTGCAGCACCAGACAAGAGTGCCATTCAAACTGCACTGACCTCTACAGAGCTGAACGTCTTTGTAGCA
ACCAAACTCAATGAAACCATGTTATATCCGGGCAAAAACAACCTTATCCTGCCTTGCATCGGTCGTACCGAGCGCCTCAT
CACTGATAAAGGTGAGCAGTTTGCCACTATTGAGGACTCAATGTGTCAAGTTGTGGCGACCAGAGGACGCATAAAGCCTA
TCAGCGACGCGCTAAAATCCGAAGCGCAAATCGTTGCAGATATGGCAACTCATGTACTTGGAACTGAATCCTCAATCCCT
TGGCAAGCGATGAGTACGGATTTTGATATTATTCGTGATTATATTGCGCAAGCGATTGAAGGGTTTGAAAACTTTAATCA
GCGTATTCGTGCCGCTGAGCGTGGTTTTCACTTGTATCATGCGGCGCGTCATCGGATTTGGAATACGGATAGTGGTAAAG
CACAGTTTGAAGTACCGCAATATCCGATTACCTACGTTGCCGCGCAAATGGCACAAACGACATTCGATTATCAAAATAAT
TCAGTAAACAATCAAATCTTTGATATGAACCAGTCCGCTGAGCAAAACGTCTGGCAACTAACAAGTGTCCGTAGTCATGA
CCAATTTAACACCATGATATTCGGCTTCCAAGATCGCTACCGACAGACTGATCGTCGTGATGTGCTCTTTATGCATCCAG
ATGAAATCAGTCGCTTAGGTTGGCAAAAAGGCGATCAAATCATGGTATCGCGCCAAGACAGTCAAAATGCTGAGCGCACG
TTAGGACCTTTGATACTAACAGAGATGGATATTGCAGCGAATGCAGTGGCAACCTATTATCCTGAATGTAATGACCTCCT
TGATTTGGACAGTCATGCGCCGGAATCCAGAACACCTGCTTATAAGTCTGTTACCGTGGTATTGAAGTGTGTTGAACAAA
GCAGTATGGCAACTGCCGTATGA

Upstream 100 bases:

>100_bases
ATATCGCCACTTTGCCACTAGCCATTATATAGTAAGCGTTTATACATCTGCTCTTAGTAAAATGACCGTTATCTATCAGC
ACTCGCCTATAAGGTTTATC

Downstream 100 bases:

>100_bases
TGGGTATCTCGGCATTAGGACTTTTATTTTATTGATAACACAGGCTAATAAGCACTCACAATGGCAAACAAACCTCACTT
GGCTGCAGAAGATAGCTTTA

Product: oxidoreductase alpha (molybdopterin) subunit

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MRKIPVYIHPAAGWPALIASTRTLMDYKAFLRGSISVLHSNQPKDGFDCPGCAWPDHKSNKAIDVCENGIKVIASETMNR
RADATFFANNTVTALQGWSGYELEHSGRLSEPLYYYAAQDRYLPISWQAAYEIIADQLKQLDSPDEALFYTSGRVTNEPA
FMFQLFVRCFGTNNLPDCSNMCHEPTSVMLGKQLGIGKATVILEDFEQAKLILLFGQNPATNHPRMLEMLAHAHKQGCRI
ISINPMREQGLSKFRNPQKPSHMAAGQSDEMVDEVIQIQIGGDAALLTGMAKWLTKNGKMNSGFIEQHTSGYDALDAWLH
QQSWTDVELGCGISKAEIIMLAKLVAESPATICTWGMGITQHVQGEDNVAMITNLLLLMGMIGIDGAGASPVRGHSNVQG
DRTMGIHERPKQSLLDSLERVFKQPMPQEDGLDVIAGAKALIKGDIKAFVSMGGNYAVAAPDKSAIQTALTSTELNVFVA
TKLNETMLYPGKNNLILPCIGRTERLITDKGEQFATIEDSMCQVVATRGRIKPISDALKSEAQIVADMATHVLGTESSIP
WQAMSTDFDIIRDYIAQAIEGFENFNQRIRAAERGFHLYHAARHRIWNTDSGKAQFEVPQYPITYVAAQMAQTTFDYQNN
SVNNQIFDMNQSAEQNVWQLTSVRSHDQFNTMIFGFQDRYRQTDRRDVLFMHPDEISRLGWQKGDQIMVSRQDSQNAERT
LGPLILTEMDIAANAVATYYPECNDLLDLDSHAPESRTPAYKSVTVVLKCVEQSSMATAV

Sequences:

>Translated_780_residues
MRKIPVYIHPAAGWPALIASTRTLMDYKAFLRGSISVLHSNQPKDGFDCPGCAWPDHKSNKAIDVCENGIKVIASETMNR
RADATFFANNTVTALQGWSGYELEHSGRLSEPLYYYAAQDRYLPISWQAAYEIIADQLKQLDSPDEALFYTSGRVTNEPA
FMFQLFVRCFGTNNLPDCSNMCHEPTSVMLGKQLGIGKATVILEDFEQAKLILLFGQNPATNHPRMLEMLAHAHKQGCRI
ISINPMREQGLSKFRNPQKPSHMAAGQSDEMVDEVIQIQIGGDAALLTGMAKWLTKNGKMNSGFIEQHTSGYDALDAWLH
QQSWTDVELGCGISKAEIIMLAKLVAESPATICTWGMGITQHVQGEDNVAMITNLLLLMGMIGIDGAGASPVRGHSNVQG
DRTMGIHERPKQSLLDSLERVFKQPMPQEDGLDVIAGAKALIKGDIKAFVSMGGNYAVAAPDKSAIQTALTSTELNVFVA
TKLNETMLYPGKNNLILPCIGRTERLITDKGEQFATIEDSMCQVVATRGRIKPISDALKSEAQIVADMATHVLGTESSIP
WQAMSTDFDIIRDYIAQAIEGFENFNQRIRAAERGFHLYHAARHRIWNTDSGKAQFEVPQYPITYVAAQMAQTTFDYQNN
SVNNQIFDMNQSAEQNVWQLTSVRSHDQFNTMIFGFQDRYRQTDRRDVLFMHPDEISRLGWQKGDQIMVSRQDSQNAERT
LGPLILTEMDIAANAVATYYPECNDLLDLDSHAPESRTPAYKSVTVVLKCVEQSSMATAV
>Mature_780_residues
MRKIPVYIHPAAGWPALIASTRTLMDYKAFLRGSISVLHSNQPKDGFDCPGCAWPDHKSNKAIDVCENGIKVIASETMNR
RADATFFANNTVTALQGWSGYELEHSGRLSEPLYYYAAQDRYLPISWQAAYEIIADQLKQLDSPDEALFYTSGRVTNEPA
FMFQLFVRCFGTNNLPDCSNMCHEPTSVMLGKQLGIGKATVILEDFEQAKLILLFGQNPATNHPRMLEMLAHAHKQGCRI
ISINPMREQGLSKFRNPQKPSHMAAGQSDEMVDEVIQIQIGGDAALLTGMAKWLTKNGKMNSGFIEQHTSGYDALDAWLH
QQSWTDVELGCGISKAEIIMLAKLVAESPATICTWGMGITQHVQGEDNVAMITNLLLLMGMIGIDGAGASPVRGHSNVQG
DRTMGIHERPKQSLLDSLERVFKQPMPQEDGLDVIAGAKALIKGDIKAFVSMGGNYAVAAPDKSAIQTALTSTELNVFVA
TKLNETMLYPGKNNLILPCIGRTERLITDKGEQFATIEDSMCQVVATRGRIKPISDALKSEAQIVADMATHVLGTESSIP
WQAMSTDFDIIRDYIAQAIEGFENFNQRIRAAERGFHLYHAARHRIWNTDSGKAQFEVPQYPITYVAAQMAQTTFDYQNN
SVNNQIFDMNQSAEQNVWQLTSVRSHDQFNTMIFGFQDRYRQTDRRDVLFMHPDEISRLGWQKGDQIMVSRQDSQNAERT
LGPLILTEMDIAANAVATYYPECNDLLDLDSHAPESRTPAYKSVTVVLKCVEQSSMATAV

Specific function: Probably involved in acid resistance [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787778, Length=781, Percent_Identity=40.7170294494238, Blast_Score=589, Evalue=1e-169,
Organism=Escherichia coli, GI3868721, Length=529, Percent_Identity=25.1417769376182, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081994, Length=384, Percent_Identity=22.65625, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.2.1.2

Molecular weight: Translated: 86659; Mature: 86659

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00075 DHFR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIPVYIHPAAGWPALIASTRTLMDYKAFLRGSISVLHSNQPKDGFDCPGCAWPDHKSN
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
KAIDVCENGIKVIASETMNRRADATFFANNTVTALQGWSGYELEHSGRLSEPLYYYAAQD
CHHHHHHCCHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEECC
RYLPISWQAAYEIIADQLKQLDSPDEALFYTSGRVTNEPAFMFQLFVRCFGTNNLPDCSN
CEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHH
MCHEPTSVMLGKQLGIGKATVILEDFEQAKLILLFGQNPATNHPRMLEMLAHAHKQGCRI
HCCCCHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEE
ISINPMREQGLSKFRNPQKPSHMAAGQSDEMVDEVIQIQIGGDAALLTGMAKWLTKNGKM
EEECCHHHHHHHHHCCCCCCCHHCCCCCHHHHHHEEEEEECCCHHHHHHHHHHHHCCCCC
NSGFIEQHTSGYDALDAWLHQQSWTDVELGCGISKAEIIMLAKLVAESPATICTWGMGIT
CCCHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
QHVQGEDNVAMITNLLLLMGMIGIDGAGASPVRGHSNVQGDRTMGIHERPKQSLLDSLER
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VFKQPMPQEDGLDVIAGAKALIKGDIKAFVSMGGNYAVAAPDKSAIQTALTSTELNVFVA
HHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCEEEEEEE
TKLNETMLYPGKNNLILPCIGRTERLITDKGEQFATIEDSMCQVVATRGRIKPISDALKS
EECCCEEECCCCCCEEEECCCCCHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHH
EAQIVADMATHVLGTESSIPWQAMSTDFDIIRDYIAQAIEGFENFNQRIRAAERGFHLYH
HHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
AARHRIWNTDSGKAQFEVPQYPITYVAAQMAQTTFDYQNNSVNNQIFDMNQSAEQNVWQL
HHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHH
TSVRSHDQFNTMIFGFQDRYRQTDRRDVLFMHPDEISRLGWQKGDQIMVSRQDSQNAERT
HHHCCCCCCCCEEEECHHHHCCCCCCCEEEECCHHHHHCCCCCCCEEEEECCCCCCHHHH
LGPLILTEMDIAANAVATYYPECNDLLDLDSHAPESRTPAYKSVTVVLKCVEQSSMATAV
HCCHHEEEHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKIPVYIHPAAGWPALIASTRTLMDYKAFLRGSISVLHSNQPKDGFDCPGCAWPDHKSN
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
KAIDVCENGIKVIASETMNRRADATFFANNTVTALQGWSGYELEHSGRLSEPLYYYAAQD
CHHHHHHCCHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEECC
RYLPISWQAAYEIIADQLKQLDSPDEALFYTSGRVTNEPAFMFQLFVRCFGTNNLPDCSN
CEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHH
MCHEPTSVMLGKQLGIGKATVILEDFEQAKLILLFGQNPATNHPRMLEMLAHAHKQGCRI
HCCCCHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEE
ISINPMREQGLSKFRNPQKPSHMAAGQSDEMVDEVIQIQIGGDAALLTGMAKWLTKNGKM
EEECCHHHHHHHHHCCCCCCCHHCCCCCHHHHHHEEEEEECCCHHHHHHHHHHHHCCCCC
NSGFIEQHTSGYDALDAWLHQQSWTDVELGCGISKAEIIMLAKLVAESPATICTWGMGIT
CCCHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
QHVQGEDNVAMITNLLLLMGMIGIDGAGASPVRGHSNVQGDRTMGIHERPKQSLLDSLER
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VFKQPMPQEDGLDVIAGAKALIKGDIKAFVSMGGNYAVAAPDKSAIQTALTSTELNVFVA
HHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCEEEEEEE
TKLNETMLYPGKNNLILPCIGRTERLITDKGEQFATIEDSMCQVVATRGRIKPISDALKS
EECCCEEECCCCCCEEEECCCCCHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHH
EAQIVADMATHVLGTESSIPWQAMSTDFDIIRDYIAQAIEGFENFNQRIRAAERGFHLYH
HHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
AARHRIWNTDSGKAQFEVPQYPITYVAAQMAQTTFDYQNNSVNNQIFDMNQSAEQNVWQL
HHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHH
TSVRSHDQFNTMIFGFQDRYRQTDRRDVLFMHPDEISRLGWQKGDQIMVSRQDSQNAERT
HHHCCCCCCCCEEEECHHHHCCCCCCCEEEECCHHHHHCCCCCCCEEEEECCCCCCHHHH
LGPLILTEMDIAANAVATYYPECNDLLDLDSHAPESRTPAYKSVTVVLKCVEQSSMATAV
HCCHHEEEHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]