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The map label for this gene is mucK [H]

Identifier: 93006060

GI number: 93006060

Start: 1500471

End: 1501736

Strand: Reverse

Name: mucK [H]

Synonym: Pcryo_1232

Alternate gene names: 93006060

Gene position: 1501736-1500471 (Counterclockwise)

Preceding gene: 93006061

Following gene: 93006059

Centisome position: 49.08

GC content: 42.1

Gene sequence:

>1266_bases
GTGAAAAGTGCGGCTATAACTTCGAATCCAAGCTTAAATTCTGCTCAGAAGCAACCTTGGAAACTGGCCTTTGTATTTTG
TTTTTTAGTCTTGTTATGTGATGGGGCTGATATCGGTATTCTTGCCTTTACGCTTTCAAGTTTAAAACAAGAATTTGGAT
TGACTAATGTACAAGCAGGTGCTTTGGGCAGTTGGTCATTATTTGGCATGGCAATCGGTGGGTTCTTTGGCGGCTGGGCC
TGTGATCGTTTTGGACGGGTACGGGTTATCGTGATTGCGACCGCACTCTTCTCTGTATTATCAGGTTTTAGTGGGTTTGC
GCAGAGCTACGAACATTTTGTAGCATTACGATTCACCGCATGTTTGGGTCTTGGTAGCTTATACATTGCGACCAATACGT
TGATGTCTGAGATGGTCCCTACTAAACATCGAACGACGGTACTTGCGATGTTGATGACAGGGTTTACTTTAGGCTCTCTC
GTTATTACGAGCCTGTCTGCTTGGATTATTCCTAGCTATGGTTGGCGCACCCTATACCTCTTAACCTTTATACCTATTAT
TCTTGCAGTATTGATGTATTTTCTAGTGTCTGAGCCGCAGTCTTGGAAAGAGTCACGTGCCCTTAAACTTAGTGGCGCAA
AGAACTCACTTCAAAAACCTGAAAACCCTTACAAAGCCATATTTGAGAATCCAAAGCATCGCATCATGTTTATTTTATGG
TCTATGAGTTCAGGGCTTTTATTATTTGGTTATTTTGGCGTAAGCAACTGGTTACCGTCTTATCTAGAAACTGAATTAGG
TATCAAGTTTAAAGAGATGGCTATCTATATGGCAGGTACTTATCTGACTATGATGTTTGCCAAATTAGTCGCAGGTATCG
TGGCTGATAAGATAGGTCGCAAGATAGTATTTGCTTTCGGTACGATGGGTACGGCACTATTTATACCAGTATTGGTCTAC
ATGCATACGCCAGAAAACATCGGTTGGTTAATGATAACCTTTGGCTTCTTATATGGTATTCCTTATGCAATTAACGCCAC
CTATTTGACCGAAAGCTTTCCAACTGCTATTCGAGGTACTGCTATCGGTGGTGCATTCAATATCGGACGACTGGGCTCAG
TCATTGCACCCGTCGCTATTGGTTATATGGCGATGCAAAATTCTATCGGTGCAGGTTTATTGCTGATGGCAGGTGCGTAC
TTCTTATGTGGTCTTATTCCGACGTTGTTTATTAAAGAACAGCAGTATGACCCACAAAAAGCATAA

Upstream 100 bases:

>100_bases
TGATGAGCTAGGCGATACCGGTATTTGCTAGGACGTGAATACCGTCATAAAGACACTATCAAAATAGTTTTTTATTCTCA
CAACGATAAGGATATGTATT

Downstream 100 bases:

>100_bases
TATTATTCAATATATAAACCGCATAGCGAAATAGCTTATAATAGCTGTGCTAAGTATTTTAAATGCACCTTTAAGATAGT
ATGGTTAAAGGTGCATACTA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKSAAITSNPSLNSAQKQPWKLAFVFCFLVLLCDGADIGILAFTLSSLKQEFGLTNVQAGALGSWSLFGMAIGGFFGGWA
CDRFGRVRVIVIATALFSVLSGFSGFAQSYEHFVALRFTACLGLGSLYIATNTLMSEMVPTKHRTTVLAMLMTGFTLGSL
VITSLSAWIIPSYGWRTLYLLTFIPIILAVLMYFLVSEPQSWKESRALKLSGAKNSLQKPENPYKAIFENPKHRIMFILW
SMSSGLLLFGYFGVSNWLPSYLETELGIKFKEMAIYMAGTYLTMMFAKLVAGIVADKIGRKIVFAFGTMGTALFIPVLVY
MHTPENIGWLMITFGFLYGIPYAINATYLTESFPTAIRGTAIGGAFNIGRLGSVIAPVAIGYMAMQNSIGAGLLLMAGAY
FLCGLIPTLFIKEQQYDPQKA

Sequences:

>Translated_421_residues
MKSAAITSNPSLNSAQKQPWKLAFVFCFLVLLCDGADIGILAFTLSSLKQEFGLTNVQAGALGSWSLFGMAIGGFFGGWA
CDRFGRVRVIVIATALFSVLSGFSGFAQSYEHFVALRFTACLGLGSLYIATNTLMSEMVPTKHRTTVLAMLMTGFTLGSL
VITSLSAWIIPSYGWRTLYLLTFIPIILAVLMYFLVSEPQSWKESRALKLSGAKNSLQKPENPYKAIFENPKHRIMFILW
SMSSGLLLFGYFGVSNWLPSYLETELGIKFKEMAIYMAGTYLTMMFAKLVAGIVADKIGRKIVFAFGTMGTALFIPVLVY
MHTPENIGWLMITFGFLYGIPYAINATYLTESFPTAIRGTAIGGAFNIGRLGSVIAPVAIGYMAMQNSIGAGLLLMAGAY
FLCGLIPTLFIKEQQYDPQKA
>Mature_421_residues
MKSAAITSNPSLNSAQKQPWKLAFVFCFLVLLCDGADIGILAFTLSSLKQEFGLTNVQAGALGSWSLFGMAIGGFFGGWA
CDRFGRVRVIVIATALFSVLSGFSGFAQSYEHFVALRFTACLGLGSLYIATNTLMSEMVPTKHRTTVLAMLMTGFTLGSL
VITSLSAWIIPSYGWRTLYLLTFIPIILAVLMYFLVSEPQSWKESRALKLSGAKNSLQKPENPYKAIFENPKHRIMFILW
SMSSGLLLFGYFGVSNWLPSYLETELGIKFKEMAIYMAGTYLTMMFAKLVAGIVADKIGRKIVFAFGTMGTALFIPVLVY
MHTPENIGWLMITFGFLYGIPYAINATYLTESFPTAIRGTAIGGAFNIGRLGSVIAPVAIGYMAMQNSIGAGLLLMAGAY
FLCGLIPTLFIKEQQYDPQKA

Specific function: Probable uptake of muconate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=410, Percent_Identity=24.8780487804878, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI213021148, Length=425, Percent_Identity=23.5294117647059, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI24308167, Length=441, Percent_Identity=23.5827664399093, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI7662270, Length=156, Percent_Identity=30.1282051282051, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI216548223, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082404, Length=400, Percent_Identity=26.25, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082231, Length=435, Percent_Identity=25.0574712643678, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081723, Length=365, Percent_Identity=25.7534246575342, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789152, Length=429, Percent_Identity=21.4452214452214, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790550, Length=380, Percent_Identity=22.1052631578947, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082320, Length=392, Percent_Identity=23.9795918367347, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082159, Length=127, Percent_Identity=30.7086614173228, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788068, Length=395, Percent_Identity=21.2658227848101, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786229, Length=405, Percent_Identity=21.4814814814815, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789515, Length=427, Percent_Identity=22.0140515222482, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=417, Percent_Identity=21.3429256594724, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640198, Length=478, Percent_Identity=22.1757322175732, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640196, Length=478, Percent_Identity=22.1757322175732, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640200, Length=478, Percent_Identity=22.1757322175732, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19922874, Length=389, Percent_Identity=24.9357326478149, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330907, Length=361, Percent_Identity=23.2686980609418, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649622, Length=358, Percent_Identity=24.3016759776536, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24584153, Length=332, Percent_Identity=24.6987951807229, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46053; Mature: 46053

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAAITSNPSLNSAQKQPWKLAFVFCFLVLLCDGADIGILAFTLSSLKQEFGLTNVQAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
ALGSWSLFGMAIGGFFGGWACDRFGRVRVIVIATALFSVLSGFSGFAQSYEHFVALRFTA
CCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
CLGLGSLYIATNTLMSEMVPTKHRTTVLAMLMTGFTLGSLVITSLSAWIIPSYGWRTLYL
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LTFIPIILAVLMYFLVSEPQSWKESRALKLSGAKNSLQKPENPYKAIFENPKHRIMFILW
HHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCCHHHCCCCCCHHHHHCCCCCEEEEEEE
SMSSGLLLFGYFGVSNWLPSYLETELGIKFKEMAIYMAGTYLTMMFAKLVAGIVADKIGR
ECCCCEEEEEHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KIVFAFGTMGTALFIPVLVYMHTPENIGWLMITFGFLYGIPYAINATYLTESFPTAIRGT
EEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHEEHHHECCCCCHHHHCC
AIGGAFNIGRLGSVIAPVAIGYMAMQNSIGAGLLLMAGAYFLCGLIPTLFIKEQQYDPQK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
A
C
>Mature Secondary Structure
MKSAAITSNPSLNSAQKQPWKLAFVFCFLVLLCDGADIGILAFTLSSLKQEFGLTNVQAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
ALGSWSLFGMAIGGFFGGWACDRFGRVRVIVIATALFSVLSGFSGFAQSYEHFVALRFTA
CCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
CLGLGSLYIATNTLMSEMVPTKHRTTVLAMLMTGFTLGSLVITSLSAWIIPSYGWRTLYL
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LTFIPIILAVLMYFLVSEPQSWKESRALKLSGAKNSLQKPENPYKAIFENPKHRIMFILW
HHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCCHHHCCCCCCHHHHHCCCCCEEEEEEE
SMSSGLLLFGYFGVSNWLPSYLETELGIKFKEMAIYMAGTYLTMMFAKLVAGIVADKIGR
ECCCCEEEEEHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KIVFAFGTMGTALFIPVLVYMHTPENIGWLMITFGFLYGIPYAINATYLTESFPTAIRGT
EEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHEEHHHECCCCCHHHHCC
AIGGAFNIGRLGSVIAPVAIGYMAMQNSIGAGLLLMAGAYFLCGLIPTLFIKEQQYDPQK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]