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The map label for this gene is pcaR [H]

Identifier: 93006059

GI number: 93006059

Start: 1499428

End: 1500273

Strand: Reverse

Name: pcaR [H]

Synonym: Pcryo_1231

Alternate gene names: 93006059

Gene position: 1500273-1499428 (Counterclockwise)

Preceding gene: 93006060

Following gene: 93006058

Centisome position: 49.03

GC content: 42.67

Gene sequence:

>846_bases
ATGACAACTAAAAACCTTATTACCGAAGGCTCGGCTAACACAACACATATCGAACTGCTAGAGCCGATTGCAGAGATGCG
CGACAAGAATGATCGGCAGTTCGTCACCGCGTTGGCGCGAGGGCTAGAGCTACTTCGTTGTTTTACCCCGCAGCGTCCTT
ATCTTGGTAATCAAGACTTAAGTCAATTAACAGGACTGCCTAAAGGCACGATTACGCGTCTTACTTATACTTTAGTTAAG
CTCGGCTATTTAAAGCAATCAATAAATAGTAGTAAATATCAATTGTCTGCCGGTGTATTGGGTTTTGGCTATACGATGAT
GGCGAACATCTCTATCAACAATCTAGTAACGCCATACATGGAAGAGTTAGCAGAGTATGCAAATAGTGCGGTTGCCATGG
CCACTCGCGATCGACTAACGATGGTATATTTGAATGTGGTGCAAGGTGATGGCACTACGACTATGCGCCGTAATGTCGGC
TCATACTTACCTATTCACTTAAGTTCGATGGGCAGAGCCTGTCTAGCAAGTATGCCGCAGGCTGAGCAAGAATTTATCCT
TGATGCCATTCGCACTAAGTACAAAGAGGATTGGATAAAGATTAGAAGAGGACTAGATAAAGCTTTTAAAGATTATGAAG
ATTATGGCTATTGCTTTTCAATTAGCGAATGGCAAAAAGATGTCAATGCGGTTGCCACTGCTTTAATGCACCCTACTGAG
GGTTTACTGACTTTTAATTGTGGCGCGCCAAATTTCGTTTTGAGCCGTACAAAACTAGAGGAAGATGTTGCCCCTCGTTT
ACTGCATATGAAAAATAGTATTGAGAGCAATCTTTACATTAGCTAG

Upstream 100 bases:

>100_bases
CTATTATTAGCTCAAAGTAATTTATTCTGATAATAAAATACGATAAGCAGTATGTTGACCATTACATTTGTATTAACTTA
ATTGAGAATAAAAATAATAT

Downstream 100 bases:

>100_bases
ATCATGTCATTAATTATAGAGATCGCATAATTATTAACACTATAAGTGAGTATGCGATTTTATTATGAACTCAGTATCAT
GGAAACATACATATAATGCA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTTKNLITEGSANTTHIELLEPIAEMRDKNDRQFVTALARGLELLRCFTPQRPYLGNQDLSQLTGLPKGTITRLTYTLVK
LGYLKQSINSSKYQLSAGVLGFGYTMMANISINNLVTPYMEELAEYANSAVAMATRDRLTMVYLNVVQGDGTTTMRRNVG
SYLPIHLSSMGRACLASMPQAEQEFILDAIRTKYKEDWIKIRRGLDKAFKDYEDYGYCFSISEWQKDVNAVATALMHPTE
GLLTFNCGAPNFVLSRTKLEEDVAPRLLHMKNSIESNLYIS

Sequences:

>Translated_281_residues
MTTKNLITEGSANTTHIELLEPIAEMRDKNDRQFVTALARGLELLRCFTPQRPYLGNQDLSQLTGLPKGTITRLTYTLVK
LGYLKQSINSSKYQLSAGVLGFGYTMMANISINNLVTPYMEELAEYANSAVAMATRDRLTMVYLNVVQGDGTTTMRRNVG
SYLPIHLSSMGRACLASMPQAEQEFILDAIRTKYKEDWIKIRRGLDKAFKDYEDYGYCFSISEWQKDVNAVATALMHPTE
GLLTFNCGAPNFVLSRTKLEEDVAPRLLHMKNSIESNLYIS
>Mature_280_residues
TTKNLITEGSANTTHIELLEPIAEMRDKNDRQFVTALARGLELLRCFTPQRPYLGNQDLSQLTGLPKGTITRLTYTLVKL
GYLKQSINSSKYQLSAGVLGFGYTMMANISINNLVTPYMEELAEYANSAVAMATRDRLTMVYLNVVQGDGTTTMRRNVGS
YLPIHLSSMGRACLASMPQAEQEFILDAIRTKYKEDWIKIRRGLDKAFKDYEDYGYCFSISEWQKDVNAVATALMHPTEG
LLTFNCGAPNFVLSRTKLEEDVAPRLLHMKNSIESNLYIS

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=201, Percent_Identity=24.8756218905473, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31626; Mature: 31495

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKNLITEGSANTTHIELLEPIAEMRDKNDRQFVTALARGLELLRCFTPQRPYLGNQDL
CCCCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SQLTGLPKGTITRLTYTLVKLGYLKQSINSSKYQLSAGVLGFGYTMMANISINNLVTPYM
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHCHHHEEECCHHHHHHHHH
EELAEYANSAVAMATRDRLTMVYLNVVQGDGTTTMRRNVGSYLPIHLSSMGRACLASMPQ
HHHHHHHCCCEEHHHHCCEEEEEEEEEECCCCHHHHHHCCCCCCEEHHHHHHHHHHHCCC
AEQEFILDAIRTKYKEDWIKIRRGLDKAFKDYEDYGYCFSISEWQKDVNAVATALMHPTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCC
GLLTFNCGAPNFVLSRTKLEEDVAPRLLHMKNSIESNLYIS
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTKNLITEGSANTTHIELLEPIAEMRDKNDRQFVTALARGLELLRCFTPQRPYLGNQDL
CCCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SQLTGLPKGTITRLTYTLVKLGYLKQSINSSKYQLSAGVLGFGYTMMANISINNLVTPYM
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHCHHHEEECCHHHHHHHHH
EELAEYANSAVAMATRDRLTMVYLNVVQGDGTTTMRRNVGSYLPIHLSSMGRACLASMPQ
HHHHHHHCCCEEHHHHCCEEEEEEEEEECCCCHHHHHHCCCCCCEEHHHHHHHHHHHCCC
AEQEFILDAIRTKYKEDWIKIRRGLDKAFKDYEDYGYCFSISEWQKDVNAVATALMHPTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCC
GLLTFNCGAPNFVLSRTKLEEDVAPRLLHMKNSIESNLYIS
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]