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The map label for this gene is mmgC [H]

Identifier: 93006061

GI number: 93006061

Start: 1501846

End: 1503000

Strand: Reverse

Name: mmgC [H]

Synonym: Pcryo_1233

Alternate gene names: 93006061

Gene position: 1503000-1501846 (Counterclockwise)

Preceding gene: 93006069

Following gene: 93006060

Centisome position: 49.12

GC content: 45.11

Gene sequence:

>1155_bases
ATGATCAGAGATAAGGACGTTCTTAACCAAATCACCGACACTATCCGCCAATTTGTGAATAACCAATTAATACCGATGGA
ACACTGGGTAGCAGAAAACGACCGTCTTCCAGACGATATCATCAATCAAATGCGCGAGTTAGGGCTGTTTGGACTGACTA
TTCCCGAAGAGTATGGCGGGCTTGGCGTTACGATGGAAGAAGAGGTCACACTGGCATTTGAATTAGGACGCACCTCTCCT
GCTTTTCGCTCATTGATAGGGACAAATAACGGTATCGGCTCATCTGGACTAGTCATTGATGGTACTGAAGCGCAAAAACA
GAAATATCTACCAAGGCTCGCCAGTGGTGAAATCATCGGCTCATTTTGTTTGACCGAGCCGGATTCTGGCTCAGATGCCG
CTTCATTAAAGACCACTGCTATCAAGGACGGTGATACCTATATTATCAACGGTACTAAGCGCTATATTACCAACGCCCCT
GAAGCCGGCGTATTTACCGTAATGGCACGTACTGACCCACAAAATAAAAGATCGGGTGGCATTTCAGCCTTTATCGTTGA
GAGCGATACCCCTGGTATTACTTTGGGTAAAATTGACAAAAAAATGGGACAAAAAGGCGCTCATACCTGTGATGTTATCT
TTGATAATTGTATCGTGCCTGCTGATGCTTTGATTGGTGGTGTCGAAGGTGTAGGTTTCAAAACCGCGATGAAAGTACTT
GATAAAGGGCGCCTACATATTGCTGCAGCGAGTACCGGAGCCGCTACTCGTATGTTGGATGATGCATTACATTATGCCGT
TGAACGTAAGCAGTTTGGGCAACCGATTGCCAACTTCCAACTTATTCAAGCGATGCTCGCTGATTCAAAAGCGGAAATTT
ATGCGGCTAAATCTATGGTATTAGACGCCTCACGCCTGCGTGATGAAGGTAAAGATGTCGTCACTGAGTCCTCCTGTGCC
AAGATGTTTGCTACTGAAATGTGTGGCCGCGTTGCTGATAGAGCTGTGCAAATTCATGGCGGTGCGGGTTATATTGCCGA
TTATGGCATTGAGCGTTTTTATCGTGATGTGCGCTTATATCGTTTATATGAAGGTACGACTCAGATTCAGCAGATTATCA
TCGCCCGTAATATGATTAAAGAAGTAAGTGAATAG

Upstream 100 bases:

>100_bases
AAAACTATTGTAATTTCATAAACTATCAATTATGCTGTTTGTTCAAGGCCATTATGAAGCCGCTCTCAATTTGAATATCA
ATTAAACAAGGAAGAATCAC

Downstream 100 bases:

>100_bases
TAGTTTGTTTGATGAGCTAGGCGATACCGGTATTTGCTAGGACGTGAATACCGTCATAAAGACACTATCAAAATAGTTTT
TTATTCTCACAACGATAAGG

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MIRDKDVLNQITDTIRQFVNNQLIPMEHWVAENDRLPDDIINQMRELGLFGLTIPEEYGGLGVTMEEEVTLAFELGRTSP
AFRSLIGTNNGIGSSGLVIDGTEAQKQKYLPRLASGEIIGSFCLTEPDSGSDAASLKTTAIKDGDTYIINGTKRYITNAP
EAGVFTVMARTDPQNKRSGGISAFIVESDTPGITLGKIDKKMGQKGAHTCDVIFDNCIVPADALIGGVEGVGFKTAMKVL
DKGRLHIAAASTGAATRMLDDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKSMVLDASRLRDEGKDVVTESSCA
KMFATEMCGRVADRAVQIHGGAGYIADYGIERFYRDVRLYRLYEGTTQIQQIIIARNMIKEVSE

Sequences:

>Translated_384_residues
MIRDKDVLNQITDTIRQFVNNQLIPMEHWVAENDRLPDDIINQMRELGLFGLTIPEEYGGLGVTMEEEVTLAFELGRTSP
AFRSLIGTNNGIGSSGLVIDGTEAQKQKYLPRLASGEIIGSFCLTEPDSGSDAASLKTTAIKDGDTYIINGTKRYITNAP
EAGVFTVMARTDPQNKRSGGISAFIVESDTPGITLGKIDKKMGQKGAHTCDVIFDNCIVPADALIGGVEGVGFKTAMKVL
DKGRLHIAAASTGAATRMLDDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKSMVLDASRLRDEGKDVVTESSCA
KMFATEMCGRVADRAVQIHGGAGYIADYGIERFYRDVRLYRLYEGTTQIQQIIIARNMIKEVSE
>Mature_384_residues
MIRDKDVLNQITDTIRQFVNNQLIPMEHWVAENDRLPDDIINQMRELGLFGLTIPEEYGGLGVTMEEEVTLAFELGRTSP
AFRSLIGTNNGIGSSGLVIDGTEAQKQKYLPRLASGEIIGSFCLTEPDSGSDAASLKTTAIKDGDTYIINGTKRYITNAP
EAGVFTVMARTDPQNKRSGGISAFIVESDTPGITLGKIDKKMGQKGAHTCDVIFDNCIVPADALIGGVEGVGFKTAMKVL
DKGRLHIAAASTGAATRMLDDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKSMVLDASRLRDEGKDVVTESSCA
KMFATEMCGRVADRAVQIHGGAGYIADYGIERFYRDVRLYRLYEGTTQIQQIIIARNMIKEVSE

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=38.1720430107527, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI76496475, Length=375, Percent_Identity=38.9333333333333, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI4557235, Length=375, Percent_Identity=38.9333333333333, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI21361497, Length=373, Percent_Identity=39.4101876675603, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=35.5978260869565, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI187960098, Length=368, Percent_Identity=38.0434782608696, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI4557231, Length=368, Percent_Identity=38.0434782608696, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI226958412, Length=370, Percent_Identity=36.2162162162162, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI7656849, Length=368, Percent_Identity=37.7717391304348, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI226958414, Length=360, Percent_Identity=36.9444444444444, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI4501857, Length=371, Percent_Identity=32.3450134770889, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4503943, Length=371, Percent_Identity=34.2318059299191, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI7669494, Length=359, Percent_Identity=33.983286908078, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI48976061, Length=397, Percent_Identity=28.463476070529, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI211971008, Length=397, Percent_Identity=28.463476070529, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI38505218, Length=388, Percent_Identity=27.5773195876289, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1786223, Length=366, Percent_Identity=29.7814207650273, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI87081958, Length=372, Percent_Identity=31.7204301075269, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87081702, Length=331, Percent_Identity=29.3051359516616, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082384, Length=273, Percent_Identity=26.007326007326, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=39.1534391534392, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=38.1868131868132, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI17570075, Length=372, Percent_Identity=37.6344086021505, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=36.9109947643979, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17508101, Length=368, Percent_Identity=36.9565217391304, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71985184, Length=398, Percent_Identity=37.4371859296482, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=37.037037037037, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17533517, Length=378, Percent_Identity=33.0687830687831, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71990804, Length=286, Percent_Identity=39.8601398601399, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71985192, Length=345, Percent_Identity=37.1014492753623, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=42.6724137931034, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17534353, Length=371, Percent_Identity=31.8059299191375, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=33.7037037037037, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=26.6666666666667, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17505929, Length=349, Percent_Identity=28.080229226361, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=33.195020746888, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=393, Percent_Identity=27.735368956743, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI86563383, Length=274, Percent_Identity=26.6423357664234, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=274, Percent_Identity=26.6423357664234, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17531913, Length=178, Percent_Identity=28.6516853932584, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=38.0697050938338, Blast_Score=261, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24660351, Length=371, Percent_Identity=38.2749326145553, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=37.5335120643432, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI281363737, Length=381, Percent_Identity=36.2204724409449, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=36.8279569892473, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=31.7333333333333, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI19920834, Length=370, Percent_Identity=32.1621621621622, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24652780, Length=351, Percent_Identity=24.7863247863248, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281365206, Length=379, Percent_Identity=25.8575197889182, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24585193, Length=379, Percent_Identity=25.8575197889182, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24585195, Length=379, Percent_Identity=25.8575197889182, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24585191, Length=379, Percent_Identity=25.8575197889182, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41848; Mature: 41848

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDKDVLNQITDTIRQFVNNQLIPMEHWVAENDRLPDDIINQMRELGLFGLTIPEEYGG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHCCEEEEECCHHHCC
LGVTMEEEVTLAFELGRTSPAFRSLIGTNNGIGSSGLVIDGTEAQKQKYLPRLASGEIIG
CCCEECCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCEEE
SFCLTEPDSGSDAASLKTTAIKDGDTYIINGTKRYITNAPEAGVFTVMARTDPQNKRSGG
HEECCCCCCCCCCCCEEEEEEECCCEEEECCCHHHHCCCCCCCEEEEEEECCCCCCCCCC
ISAFIVESDTPGITLGKIDKKMGQKGAHTCDVIFDNCIVPADALIGGVEGVGFKTAMKVL
EEEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHH
DKGRLHIAAASTGAATRMLDDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKSMV
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LDASRLRDEGKDVVTESSCAKMFATEMCGRVADRAVQIHGGAGYIADYGIERFYRDVRLY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHH
RLYEGTTQIQQIIIARNMIKEVSE
HHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRDKDVLNQITDTIRQFVNNQLIPMEHWVAENDRLPDDIINQMRELGLFGLTIPEEYGG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHCCEEEEECCHHHCC
LGVTMEEEVTLAFELGRTSPAFRSLIGTNNGIGSSGLVIDGTEAQKQKYLPRLASGEIIG
CCCEECCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCEEE
SFCLTEPDSGSDAASLKTTAIKDGDTYIINGTKRYITNAPEAGVFTVMARTDPQNKRSGG
HEECCCCCCCCCCCCEEEEEEECCCEEEECCCHHHHCCCCCCCEEEEEEECCCCCCCCCC
ISAFIVESDTPGITLGKIDKKMGQKGAHTCDVIFDNCIVPADALIGGVEGVGFKTAMKVL
EEEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHH
DKGRLHIAAASTGAATRMLDDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKSMV
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LDASRLRDEGKDVVTESSCAKMFATEMCGRVADRAVQIHGGAGYIADYGIERFYRDVRLY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHH
RLYEGTTQIQQIIIARNMIKEVSE
HHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]