Click here to switch to the map view.

The map label for this gene is rfbB [C]

Identifier: 93005447

GI number: 93005447

Start: 734360

End: 735361

Strand: Direct

Name: rfbB [C]

Synonym: Pcryo_0617

Alternate gene names: 93005447

Gene position: 734360-735361 (Clockwise)

Preceding gene: 93005446

Following gene: 93005448

Centisome position: 24.0

GC content: 37.23

Gene sequence:

>1002_bases
ATGATTGAACTTACGGGCAAGAAAATATTCATCACAGGTGGTGCGGGATTTATTGGATCAACTCTAATCGGTAGATTAAT
CGAAAACAACGAAATGATCGTTTATGATAATTTAGAACGTAACACTTTGAAAAGTCAACCCTTTGCTAATCATAAAAATC
TAACATTAATACAGGGCAATGTGTTAGATCAAGAAAAAATTATTGAAGCAGCAAAAGGTAGTGAGATATTTATACATGCC
GCCGCTATAGCAGGTATTGATAATACTGTTAAAAGTCCAGTTCGTACTATGACAGTAAATATGATTGGAACTGCCAATGC
GCTTGAAGCCGCACATCAAGCAGGCACTGTACAAAGATTTCTAGAGTTTTCAACTTCAGAGGTGTTTGGTTCTAGAGCTT
ATAGGGTAGACGAGCTAAATTCTACTACTACAGGAGCAGTTGGTGAAGCCCGTTGGACGTATGCAGTAAGTAAACTTGCT
GGTGAACACTTAACTCATGCTTATAATCGTGAGCATGGATTACCGACTGTTACTTTTAGGCCTTTTAACGTTTACGGACC
TGGACAGATTGGTGAAGGTGCCATCTCTATTATGATTCGTAAAGCCCTAAATAATGAAGATATTTATATTTTTGGTGATG
GTTCTCAAATCAGAGCGTGGTGTTATGTAGATGATATGATTGATGCCTTGATGAAAGCATTATCTGTACCTCAAGCGATA
GGAGAGTCTTTCAATATTGGTAACGCAAGAGCAATAACAACTATTTATGGTTTAGCCCAAACCATTTGTCGAGTGCTTAA
CTCAAAGTCAGAAATAATATTTAGAGAGGCGCTTTCTGCAGATATTGAACTGCGTATACCCAATGTTGATAAATCTGAAG
AGTTATTGGGCTTTAAAGCACAAGTAGACTTAGAAGAAGGTTTAATTCGTACAGCAGACTGGCTATCAGCTAATATGAAT
GATTTGCCAGTAATGCCAGATATGTTTTTGAAGGAAAAATAA

Upstream 100 bases:

>100_bases
AGCGAGTGATGAGTTTGCCGATGCACCCATATATGCAAACTACAGATATTAAAACTATTTGTAATTCATTTTAAATTTTA
AATAACCAAAGAGATAACTA

Downstream 100 bases:

>100_bases
TATGATTAAGCTCTCACAGCCTACAATTCCAGAAGCAGCAATTGAGCGTGTTAGTGAAATTCTACGAAGTGGGCAACTTG
TTCATGGTGAAGAATGTGAA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIELTGKKIFITGGAGFIGSTLIGRLIENNEMIVYDNLERNTLKSQPFANHKNLTLIQGNVLDQEKIIEAAKGSEIFIHA
AAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRFLEFSTSEVFGSRAYRVDELNSTTTGAVGEARWTYAVSKLA
GEHLTHAYNREHGLPTVTFRPFNVYGPGQIGEGAISIMIRKALNNEDIYIFGDGSQIRAWCYVDDMIDALMKALSVPQAI
GESFNIGNARAITTIYGLAQTICRVLNSKSEIIFREALSADIELRIPNVDKSEELLGFKAQVDLEEGLIRTADWLSANMN
DLPVMPDMFLKEK

Sequences:

>Translated_333_residues
MIELTGKKIFITGGAGFIGSTLIGRLIENNEMIVYDNLERNTLKSQPFANHKNLTLIQGNVLDQEKIIEAAKGSEIFIHA
AAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRFLEFSTSEVFGSRAYRVDELNSTTTGAVGEARWTYAVSKLA
GEHLTHAYNREHGLPTVTFRPFNVYGPGQIGEGAISIMIRKALNNEDIYIFGDGSQIRAWCYVDDMIDALMKALSVPQAI
GESFNIGNARAITTIYGLAQTICRVLNSKSEIIFREALSADIELRIPNVDKSEELLGFKAQVDLEEGLIRTADWLSANMN
DLPVMPDMFLKEK
>Mature_333_residues
MIELTGKKIFITGGAGFIGSTLIGRLIENNEMIVYDNLERNTLKSQPFANHKNLTLIQGNVLDQEKIIEAAKGSEIFIHA
AAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRFLEFSTSEVFGSRAYRVDELNSTTTGAVGEARWTYAVSKLA
GEHLTHAYNREHGLPTVTFRPFNVYGPGQIGEGAISIMIRKALNNEDIYIFGDGSQIRAWCYVDDMIDALMKALSVPQAI
GESFNIGNARAITTIYGLAQTICRVLNSKSEIIFREALSADIELRIPNVDKSEELLGFKAQVDLEEGLIRTADWLSANMN
DLPVMPDMFLKEK

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=322, Percent_Identity=32.2981366459627, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI7657641, Length=333, Percent_Identity=30.3303303303303, Blast_Score=124, Evalue=9e-29,
Organism=Escherichia coli, GI48994969, Length=338, Percent_Identity=29.2899408284024, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788353, Length=347, Percent_Identity=30.5475504322767, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788365, Length=337, Percent_Identity=25.5192878338279, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788589, Length=349, Percent_Identity=25.5014326647564, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786974, Length=344, Percent_Identity=22.3837209302326, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539532, Length=326, Percent_Identity=31.5950920245399, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=27.6923076923077, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI115532424, Length=270, Percent_Identity=28.5185185185185, Blast_Score=98, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6319493, Length=351, Percent_Identity=24.5014245014245, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356223, Length=318, Percent_Identity=32.0754716981132, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36576; Mature: 36576

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELTGKKIFITGGAGFIGSTLIGRLIENNEMIVYDNLERNTLKSQPFANHKNLTLIQGN
CEEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCCCCCCEEEEECC
VLDQEKIIEAAKGSEIFIHAAAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRF
CCCHHHHHHHCCCCEEEEEEEEHHCCCHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHH
LEFSTSEVFGSRAYRVDELNSTTTGAVGEARWTYAVSKLAGEHLTHAYNREHGLPTVTFR
HHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
PFNVYGPGQIGEGAISIMIRKALNNEDIYIFGDGSQIRAWCYVDDMIDALMKALSVPQAI
CEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEHHHHHHHHHHHHCCHHHH
GESFNIGNARAITTIYGLAQTICRVLNSKSEIIFREALSADIELRIPNVDKSEELLGFKA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEHHHCCCCEEEECCCCCCHHHHHCEEE
QVDLEEGLIRTADWLSANMNDLPVMPDMFLKEK
EEEHHHCHHHHHHHHHCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MIELTGKKIFITGGAGFIGSTLIGRLIENNEMIVYDNLERNTLKSQPFANHKNLTLIQGN
CEEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCCCCCCEEEEECC
VLDQEKIIEAAKGSEIFIHAAAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRF
CCCHHHHHHHCCCCEEEEEEEEHHCCCHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHH
LEFSTSEVFGSRAYRVDELNSTTTGAVGEARWTYAVSKLAGEHLTHAYNREHGLPTVTFR
HHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
PFNVYGPGQIGEGAISIMIRKALNNEDIYIFGDGSQIRAWCYVDDMIDALMKALSVPQAI
CEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEHHHHHHHHHHHHCCHHHH
GESFNIGNARAITTIYGLAQTICRVLNSKSEIIFREALSADIELRIPNVDKSEELLGFKA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEHHHCCCCEEEECCCCCCHHHHHCEEE
QVDLEEGLIRTADWLSANMNDLPVMPDMFLKEK
EEEHHHCHHHHHHHHHCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]