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The map label for this gene is trpB [H]

Identifier: 93005297

GI number: 93005297

Start: 572933

End: 574207

Strand: Direct

Name: trpB [H]

Synonym: Pcryo_0467

Alternate gene names: 93005297

Gene position: 572933-574207 (Clockwise)

Preceding gene: 93005296

Following gene: 93005298

Centisome position: 18.72

GC content: 45.49

Gene sequence:

>1275_bases
ATGAGTCATGTCGCTAACAAAGATGTATCTGCCACCGCACACGCTATTAATAGCTTTACTAATCCAGAAAGCGTGCAAGA
TTTTAACCAGTATCCTGATGCGCGAGGACATTTTGGCGTCCACGGCGGACGCTTTGTCTCTGAAACCTTGATGGCAGCGT
TAGAAGAGCTAGAAACGTTATATAACACAGTCAAAAAAGACCCTGCATTTTGGGAAGAATATCACAATGATTTGGTCAAC
TATGTTGGACGCCCAACGCCTCTCTATCATGCCAAGCGTCTAAGTGATGAGATTGGCGGTGCGCAGATTTACTTTAAGCG
TGAAGATCTTAATCATACTGGCGCGCATAAGGTCAATAATACTATTGGTCAAGCGCTCCTTGCCAAAATGAGTGGCAAAA
AACGTATTATTGCAGAAACTGGAGCAGGGCAACATGGCGTTGCGACGGCGACGATTGCCGCGCGTTTGGGACTAGAGTGT
ATCGTTTATATGGGCGCGGACGATGTTGAGCGTCAAAAGATGAACGTCTATCGTATGCGTTTACTTGGTGCGACAGTTGT
GCCGGTAACATCTGGCTCACGTACTCTCAAAGATGCGATGAATGAAGCCATGCGTGATTGGGTTACCAATGTGGATAGCA
CATATTATATTATTGGTACGGTTGCAGGTCCGCATCCTTATCCGTTACTCGTACGCGACTTCCAAGCAATTATTGGTAAA
GAAGCGCGTGTGCAACATCTGCAAATGACGGGTAAATTACCAGATGCGCTAGTCGCTTGTGTTGGCGGCGGCTCAAATGC
CATTGGTCTATTCTTTGACTTCTTAAATGATAATGACGTTAAAATGTATGGCGTGGAAGCAACAGGTGATGGTATTGAGA
CGGGTCGTCATTCTGCACCATTAGCTGCTGGTCGTATTGGTGTATTACACGGTAACCGTACTTACTTGATGGCCGATGAT
GAAGGTCAAATCCAAGAAACCCATTCTATCTCAGCTGGTCTTGATTACCCTGGTGTTGGTCCTGAGCATAGCTTCTTAAA
AGATATGAAGCGTGTTGAATATGTTGGTTGTACCGATAAGGAGTCGTTAGAAGGTTTCCATGAAGTCACGCGTAAAGAAG
GCATCATTCCGGCGCTTGAATCTGCTCATGCGGTTGCTTATGCACTAAAGCTGGCTAAAACGATGACGCCTGATCAAACC
ATTATCGTCAATATGTCTGGTCGCGGTGATAAAGATTTGCATTCGGTGATGAAGGCAGAAGGGATTGAGCTTTAA

Upstream 100 bases:

>100_bases
CTGTCAAATTGCCAAAGCAAACTATGTAAACAGTTTTCCCTATAGTTTTTCTAAAAAACAGATATCCTAAAAAATACCAC
TTATTACAGTAGGAATTACC

Downstream 100 bases:

>100_bases
TAGCTACTTTTTAGTAACAACTGGATTATTCCTTGGAAGAAAAATTACTGATTTGACCCGTTATTATTAAATAAAGGGTC
AAATGAGCCAGTTTATAATA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSHVANKDVSATAHAINSFTNPESVQDFNQYPDARGHFGVHGGRFVSETLMAALEELETLYNTVKKDPAFWEEYHNDLVN
YVGRPTPLYHAKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLEC
IVYMGADDVERQKMNVYRMRLLGATVVPVTSGSRTLKDAMNEAMRDWVTNVDSTYYIIGTVAGPHPYPLLVRDFQAIIGK
EARVQHLQMTGKLPDALVACVGGGSNAIGLFFDFLNDNDVKMYGVEATGDGIETGRHSAPLAAGRIGVLHGNRTYLMADD
EGQIQETHSISAGLDYPGVGPEHSFLKDMKRVEYVGCTDKESLEGFHEVTRKEGIIPALESAHAVAYALKLAKTMTPDQT
IIVNMSGRGDKDLHSVMKAEGIEL

Sequences:

>Translated_424_residues
MSHVANKDVSATAHAINSFTNPESVQDFNQYPDARGHFGVHGGRFVSETLMAALEELETLYNTVKKDPAFWEEYHNDLVN
YVGRPTPLYHAKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLEC
IVYMGADDVERQKMNVYRMRLLGATVVPVTSGSRTLKDAMNEAMRDWVTNVDSTYYIIGTVAGPHPYPLLVRDFQAIIGK
EARVQHLQMTGKLPDALVACVGGGSNAIGLFFDFLNDNDVKMYGVEATGDGIETGRHSAPLAAGRIGVLHGNRTYLMADD
EGQIQETHSISAGLDYPGVGPEHSFLKDMKRVEYVGCTDKESLEGFHEVTRKEGIIPALESAHAVAYALKLAKTMTPDQT
IIVNMSGRGDKDLHSVMKAEGIEL
>Mature_423_residues
SHVANKDVSATAHAINSFTNPESVQDFNQYPDARGHFGVHGGRFVSETLMAALEELETLYNTVKKDPAFWEEYHNDLVNY
VGRPTPLYHAKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLECI
VYMGADDVERQKMNVYRMRLLGATVVPVTSGSRTLKDAMNEAMRDWVTNVDSTYYIIGTVAGPHPYPLLVRDFQAIIGKE
ARVQHLQMTGKLPDALVACVGGGSNAIGLFFDFLNDNDVKMYGVEATGDGIETGRHSAPLAAGRIGVLHGNRTYLMADDE
GQIQETHSISAGLDYPGVGPEHSFLKDMKRVEYVGCTDKESLEGFHEVTRKEGIIPALESAHAVAYALKLAKTMTPDQTI
IVNMSGRGDKDLHSVMKAEGIEL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=54.3589743589744, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=395, Percent_Identity=56.2025316455696, Blast_Score=473, Evalue=1e-134,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 46245; Mature: 46114

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVANKDVSATAHAINSFTNPESVQDFNQYPDARGHFGVHGGRFVSETLMAALEELETL
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YNTVKKDPAFWEEYHNDLVNYVGRPTPLYHAKRLSDEIGGAQIYFKREDLNHTGAHKVNN
HHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHH
TIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLECIVYMGADDVERQKMNVYRMR
HHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHH
LLGATVVPVTSGSRTLKDAMNEAMRDWVTNVDSTYYIIGTVAGPHPYPLLVRDFQAIIGK
HHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
EARVQHLQMTGKLPDALVACVGGGSNAIGLFFDFLNDNDVKMYGVEATGDGIETGRHSAP
HHHHHHHHHCCCCCHHHEEEECCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCC
LAAGRIGVLHGNRTYLMADDEGQIQETHSISAGLDYPGVGPEHSFLKDMKRVEYVGCTDK
CCCCEEEEEECCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCH
ESLEGFHEVTRKEGIIPALESAHAVAYALKLAKTMTPDQTIIVNMSGRGDKDLHSVMKAE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHC
GIEL
CCCC
>Mature Secondary Structure 
SHVANKDVSATAHAINSFTNPESVQDFNQYPDARGHFGVHGGRFVSETLMAALEELETL
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YNTVKKDPAFWEEYHNDLVNYVGRPTPLYHAKRLSDEIGGAQIYFKREDLNHTGAHKVNN
HHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHH
TIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLECIVYMGADDVERQKMNVYRMR
HHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHH
LLGATVVPVTSGSRTLKDAMNEAMRDWVTNVDSTYYIIGTVAGPHPYPLLVRDFQAIIGK
HHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
EARVQHLQMTGKLPDALVACVGGGSNAIGLFFDFLNDNDVKMYGVEATGDGIETGRHSAP
HHHHHHHHHCCCCCHHHEEEECCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCC
LAAGRIGVLHGNRTYLMADDEGQIQETHSISAGLDYPGVGPEHSFLKDMKRVEYVGCTDK
CCCCEEEEEECCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCH
ESLEGFHEVTRKEGIIPALESAHAVAYALKLAKTMTPDQTIIVNMSGRGDKDLHSVMKAE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHC
GIEL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA