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The map label for this gene is trpF [H]

Identifier: 93005296

GI number: 93005296

Start: 572141

End: 572824

Strand: Direct

Name: trpF [H]

Synonym: Pcryo_0466

Alternate gene names: 93005296

Gene position: 572141-572824 (Clockwise)

Preceding gene: 93005294

Following gene: 93005297

Centisome position: 18.7

GC content: 45.03

Gene sequence:

>684_bases
ATGCACGTTAAGTTTTGTGGATTTACTCAACTTGATGATATTAAAGCTGCTGTTAAACTCAATGCGGACGCCATTGGCTT
TGTATTTTATCCGCCAAGTCCTCGTGCGGTTACAATCGAGCAGGCGCAAATATTGAGTGCTGCAGTACCGGCTTTTATCA
GTGTGGTGGCTTTGGTCGTCAATATGCCTGAAGATGAGCTTATTGAACTGGCAAATCATGTCTCTTTTGATATTATCCAA
TTTCATGGCGATGAAACGCCCGAGCAGTGCCGTCAGCTGGCAAATCTCGTCAATAAACGTTGGATTAAAGCGTTGCGTGT
CAATACTGAACAGGATGCGCTTGAGAGTGTGAATATGCAAATTGACAGTTTTGCCGCAGCAGGCGCAAGCAGCATTTTAC
TAGATGCCTACCATCAGCATAAGTATGGCGGTACAGGCGCACGCTTTGACTGGAGTCTGATACCGAATGACAGCTCACTA
CCGATTATCTTAGCCGGTGGACTTGATGCCGATAATGTCGCTGCCACTTATGACTTACCAATTTATGCCGTTGATGTCAG
CGGTGGGATTGAGTCTGATAAAGGCAAAAAAGACGTTGGCAAAATGCATGCCTTTATGAAATCAGTCAAACGCGACCGAT
GGCAAAACGAGACGCTTAGCGAATCTTCGAATATAAGTAGTTAG

Upstream 100 bases:

>100_bases
AAAACTATGAATAAAAGTATGCTAGGATAAGTTTTTGGATGCAATTGATTTGCTCCTTTATTAACAAATCATCATATTCA
GTCTTTCGCAAGGTTACCTC

Downstream 100 bases:

>100_bases
CTTTACTGCTGTCAAATTGCCAAAGCAAACTATGTAAACAGTTTTCCCTATAGTTTTTCTAAAAAACAGATATCCTAAAA
AATACCACTTATTACAGTAG

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MHVKFCGFTQLDDIKAAVKLNADAIGFVFYPPSPRAVTIEQAQILSAAVPAFISVVALVVNMPEDELIELANHVSFDIIQ
FHGDETPEQCRQLANLVNKRWIKALRVNTEQDALESVNMQIDSFAAAGASSILLDAYHQHKYGGTGARFDWSLIPNDSSL
PIILAGGLDADNVAATYDLPIYAVDVSGGIESDKGKKDVGKMHAFMKSVKRDRWQNETLSESSNISS

Sequences:

>Translated_227_residues
MHVKFCGFTQLDDIKAAVKLNADAIGFVFYPPSPRAVTIEQAQILSAAVPAFISVVALVVNMPEDELIELANHVSFDIIQ
FHGDETPEQCRQLANLVNKRWIKALRVNTEQDALESVNMQIDSFAAAGASSILLDAYHQHKYGGTGARFDWSLIPNDSSL
PIILAGGLDADNVAATYDLPIYAVDVSGGIESDKGKKDVGKMHAFMKSVKRDRWQNETLSESSNISS
>Mature_227_residues
MHVKFCGFTQLDDIKAAVKLNADAIGFVFYPPSPRAVTIEQAQILSAAVPAFISVVALVVNMPEDELIELANHVSFDIIQ
FHGDETPEQCRQLANLVNKRWIKALRVNTEQDALESVNMQIDSFAAAGASSILLDAYHQHKYGGTGARFDWSLIPNDSSL
PIILAGGLDADNVAATYDLPIYAVDVSGGIESDKGKKDVGKMHAFMKSVKRDRWQNETLSESSNISS

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=213, Percent_Identity=29.5774647887324, Blast_Score=85, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320210, Length=225, Percent_Identity=29.7777777777778, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24780; Mature: 24780

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVKFCGFTQLDDIKAAVKLNADAIGFVFYPPSPRAVTIEQAQILSAAVPAFISVVALVV
CEEEECCCCCHHHHHHHEEECCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
NMPEDELIELANHVSFDIIQFHGDETPEQCRQLANLVNKRWIKALRVNTEQDALESVNMQ
CCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCH
IDSFAAAGASSILLDAYHQHKYGGTGARFDWSLIPNDSSLPIILAGGLDADNVAATYDLP
HHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCE
IYAVDVSGGIESDKGKKDVGKMHAFMKSVKRDRWQNETLSESSNISS
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
>Mature Secondary Structure
MHVKFCGFTQLDDIKAAVKLNADAIGFVFYPPSPRAVTIEQAQILSAAVPAFISVVALVV
CEEEECCCCCHHHHHHHEEECCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
NMPEDELIELANHVSFDIIQFHGDETPEQCRQLANLVNKRWIKALRVNTEQDALESVNMQ
CCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCH
IDSFAAAGASSILLDAYHQHKYGGTGARFDWSLIPNDSSLPIILAGGLDADNVAATYDLP
HHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCE
IYAVDVSGGIESDKGKKDVGKMHAFMKSVKRDRWQNETLSESSNISS
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA