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The map label for this gene is phnW [H]

Identifier: 93005021

GI number: 93005021

Start: 223708

End: 224844

Strand: Direct

Name: phnW [H]

Synonym: Pcryo_0190

Alternate gene names: 93005021

Gene position: 223708-224844 (Clockwise)

Preceding gene: 93005020

Following gene: 93005022

Centisome position: 7.31

GC content: 45.21

Gene sequence:

>1137_bases
ATGACTGCATTACGTCAAGATATTGATCCAAACGGCTTATTAGAATATTCAGTGGTTTATACCGACCGCGCCCTTAATCA
TATGTCAAAAGCCTTCCAAGAGGTGATGAATGATTTGCTCAGCAACCTAAAAACAGTCTATAACGCTGAAGCCGCGGTTA
TTATTCCAGGTTCTGGTACCTACGGCATGGAAGCAGTCGCCCGTCAACTGACCATTGATGAAGATTGTCTCATTATCCGT
AACGGTTGGTTTAGCTATCGCTGGACGCAAATATTAGAAAAAGGCAAATTTGCCAAATCATCTACGGTACTAACGGCTGA
GCGTACAGAAGAGACGGAAGTGCCAAAACCATTTGCGCCAGTGGATATCGAAACGGCCGTTGCCAAAATTAAAGCAGACA
AATCTGCTGTCGTTTATGCGCCGCACGTTGAAACATCGTCGGGCATTATCTTATCAGAAGACTACATCAAAGCATTAAGC
GCGGCCGTACATAGTGTTGGCGGTTTATTGGTTATTGATTGTATCGCTTCAGGTTGTGTATGGTTAGATATGAAAAAATT
GGGCATTGATGTGCTCATCAGTGCGCCGCAAAAAGGCTGGAGTAGCACACCATGTGCAGGTCTGGTTATGCTCAGTGACG
CTGCTATCAAAAAGGTAGAAACCACGGAGTCTAACTGCTTTAGCCTTGATTTAAAGCAATGGTTAACCATCATGCGTGCG
TACGAAAACGGCGGTCACGCTTATCATGCGACTATGCCAACCGATAGCTTGCGTCAATTCCGCGATACTATCTTGGAAGC
AAAAGAGATTGGCTTTGATAAATTGTGTGATGCACAATGGGAGCTTGGCAACCGCGTCCGTAAGGTACTGGCAGATAAAG
GTATTGAAAGCGTTGCTGCCAAAGGTTTTGAAGCACCAGGCGTTGTCGTATCTTATACCGACCGTGATGACATCCATAAA
GGCAGTGCTTTTGCTGAAGCTGGATTGCAAATCGCTGCTGGCGTACCGTTAAAAGTGGGTGAGCCTGAGAACTTCAAAAC
GTTCCGTTTAGGTCTATTTGGTTTGGATAAATTGACCGATGTCGACGGCGCGGTAGAGCGTTTTGAAAAAGCGCTTGATG
AAGTCTTAGCAAAATGA

Upstream 100 bases:

>100_bases
ACGTTGATTAAAATAATAGCTGACCTAAATTGACTAAGACAGTATCTAGATTTTGTTATCACTCATACTTAAAAAATATT
ACAACAGACAGGAGCGTCAC

Downstream 100 bases:

>100_bases
TTTGAGAGGCTGACTCGTTTATTAACGACTATATTTATTAAGCCAGTCAGTCATCAAATGAAGAGATACTGAGCAATGCG
TGACGCAATGTTCAGTATTT

Product: class V aminotransferase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTALRQDIDPNGLLEYSVVYTDRALNHMSKAFQEVMNDLLSNLKTVYNAEAAVIIPGSGTYGMEAVARQLTIDEDCLIIR
NGWFSYRWTQILEKGKFAKSSTVLTAERTEETEVPKPFAPVDIETAVAKIKADKSAVVYAPHVETSSGIILSEDYIKALS
AAVHSVGGLLVIDCIASGCVWLDMKKLGIDVLISAPQKGWSSTPCAGLVMLSDAAIKKVETTESNCFSLDLKQWLTIMRA
YENGGHAYHATMPTDSLRQFRDTILEAKEIGFDKLCDAQWELGNRVRKVLADKGIESVAAKGFEAPGVVVSYTDRDDIHK
GSAFAEAGLQIAAGVPLKVGEPENFKTFRLGLFGLDKLTDVDGAVERFEKALDEVLAK

Sequences:

>Translated_378_residues
MTALRQDIDPNGLLEYSVVYTDRALNHMSKAFQEVMNDLLSNLKTVYNAEAAVIIPGSGTYGMEAVARQLTIDEDCLIIR
NGWFSYRWTQILEKGKFAKSSTVLTAERTEETEVPKPFAPVDIETAVAKIKADKSAVVYAPHVETSSGIILSEDYIKALS
AAVHSVGGLLVIDCIASGCVWLDMKKLGIDVLISAPQKGWSSTPCAGLVMLSDAAIKKVETTESNCFSLDLKQWLTIMRA
YENGGHAYHATMPTDSLRQFRDTILEAKEIGFDKLCDAQWELGNRVRKVLADKGIESVAAKGFEAPGVVVSYTDRDDIHK
GSAFAEAGLQIAAGVPLKVGEPENFKTFRLGLFGLDKLTDVDGAVERFEKALDEVLAK
>Mature_377_residues
TALRQDIDPNGLLEYSVVYTDRALNHMSKAFQEVMNDLLSNLKTVYNAEAAVIIPGSGTYGMEAVARQLTIDEDCLIIRN
GWFSYRWTQILEKGKFAKSSTVLTAERTEETEVPKPFAPVDIETAVAKIKADKSAVVYAPHVETSSGIILSEDYIKALSA
AVHSVGGLLVIDCIASGCVWLDMKKLGIDVLISAPQKGWSSTPCAGLVMLSDAAIKKVETTESNCFSLDLKQWLTIMRAY
ENGGHAYHATMPTDSLRQFRDTILEAKEIGFDKLCDAQWELGNRVRKVLADKGIESVAAKGFEAPGVVVSYTDRDDIHKG
SAFAEAGLQIAAGVPLKVGEPENFKTFRLGLFGLDKLTDVDGAVERFEKALDEVLAK

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=370, Percent_Identity=24.8648648648649, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321079, Length=356, Percent_Identity=25.2808988764045, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 41276; Mature: 41144

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALRQDIDPNGLLEYSVVYTDRALNHMSKAFQEVMNDLLSNLKTVYNAEAAVIIPGSGT
CCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
YGMEAVARQLTIDEDCLIIRNGWFSYRWTQILEKGKFAKSSTVLTAERTEETEVPKPFAP
CCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
VDIETAVAKIKADKSAVVYAPHVETSSGIILSEDYIKALSAAVHSVGGLLVIDCIASGCV
CCHHHHHHHHCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCE
WLDMKKLGIDVLISAPQKGWSSTPCAGLVMLSDAAIKKVETTESNCFSLDLKQWLTIMRA
EEEHHHCCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEECHHHHHHHHHH
YENGGHAYHATMPTDSLRQFRDTILEAKEIGFDKLCDAQWELGNRVRKVLADKGIESVAA
HHCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
KGFEAPGVVVSYTDRDDIHKGSAFAEAGLQIAAGVPLKVGEPENFKTFRLGLFGLDKLTD
CCCCCCCEEEEECCCCCCCCCCHHHHCCCEEECCCCEECCCCCCCEEEEEEECCCHHHCC
VDGAVERFEKALDEVLAK
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TALRQDIDPNGLLEYSVVYTDRALNHMSKAFQEVMNDLLSNLKTVYNAEAAVIIPGSGT
CCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
YGMEAVARQLTIDEDCLIIRNGWFSYRWTQILEKGKFAKSSTVLTAERTEETEVPKPFAP
CCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
VDIETAVAKIKADKSAVVYAPHVETSSGIILSEDYIKALSAAVHSVGGLLVIDCIASGCV
CCHHHHHHHHCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCE
WLDMKKLGIDVLISAPQKGWSSTPCAGLVMLSDAAIKKVETTESNCFSLDLKQWLTIMRA
EEEHHHCCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEECHHHHHHHHHH
YENGGHAYHATMPTDSLRQFRDTILEAKEIGFDKLCDAQWELGNRVRKVLADKGIESVAA
HHCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
KGFEAPGVVVSYTDRDDIHKGSAFAEAGLQIAAGVPLKVGEPENFKTFRLGLFGLDKLTD
CCCCCCCEEEEECCCCCCCCCCHHHHCCCEEECCCCEECCCCCCCEEEEEEECCCHHHCC
VDGAVERFEKALDEVLAK
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA