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The map label for this gene is yheS [H]

Identifier: 93004876

GI number: 93004876

Start: 53052

End: 55043

Strand: Direct

Name: yheS [H]

Synonym: Pcryo_0045

Alternate gene names: 93004876

Gene position: 53052-55043 (Clockwise)

Preceding gene: 93004867

Following gene: 93004878

Centisome position: 1.73

GC content: 45.88

Gene sequence:

>1992_bases
ATGATCGAATTTAAAGACGTTGGTGTTCGCCGTGATGGTCGTGAGTTGTTTGCAGGGGCAAGCTTCCAGCTACATCCGGG
CCACAAAGTTGGCTTAACGGGCAATAACGGCACCGGCAAATCAACCTTGTTTGCCTTATTATTGACGCGTATGGGCACTG
GCGATACCGAAGTGACGCTAGATAAAGGCGAAGTGAATATTCCTGATAGCTGGCATGTGGCGCATATGGCGCAGGAAGTT
GGCGCGACCACACAGACGGCGATTGATTACGTGCTAAGCGGTGATGAGCAGTGGTACGAGATTAACGCTACTTTGAATGA
TTTAAGCAGTGTCAGTGATGAGCAAATCGGTGTGCTACATCAGCAGTTTGATGAAATCGATGGCTATCGTACCCCAACCA
AAGCGGCACAAATCATGGCGGGTCTTGGTTTTAATACTAGCCAACATGAATTGCCAGTAGAAGGGTTTTCTGGTGGCTGG
CGTATGCGTCTAAACCTTGCTAAGACCTTGATGAGCCGCGCTGACTTAATGCTACTTGATGAGCCAACCAACCATTTGGA
TTTGGATGCTATTCTTTGGCTTGAGACTTGGATTAATGCCTTTACTGGTTTAGTCATCGTCATCTCGCATGACCAAACTT
TCTTAGATAATACTGTCGGTCATATTTTGCACGTTGAGCAGCAAAAAATCACCCTTTATACAGGTAACTATCAACAGTTT
ATTCGTACCCGTCATGAGCGTATGGCGCAGCAGCAGCAAGCGTTTGAGAAGCAAGAAGCGACCAAAGCACATTTGGATGA
CTTTATTCGTCGCTTCCGTGCAAAGGCTAGTAAAGCCAAGCAAGCACAGAGCCGTATTAAGCAGCTTGAGCGTATGGCGG
AGCTGTCTCCGATGATGGCGGATAACCCGTTCTCGTTCCGCTTTTATGAGCCGGCAAATATGAGCTCGCCATTGATTGAG
TTGACCGATGCGGATATTGGTTATAGCGACACGCCGCTACTTTATAATGCAAACGTACAAGTCACTCCTGATACTCGTAT
TGGGCTGCTTGGAATGAATGGCGCTGGTAAGTCGACCTTGATTAAAGCTTTGGTCGGTGAGCTTGGCGTATTAAAGGGCA
GCTATAACGTTTCTGATACGCTAAAGCTTGGCTACTTTAACCAGCATCAAATGGATATTCTTGATCCGAAGGCAACGCCG
ATAGAGATGTTGCGTCGTTTGGCAGGTAAAACGTCTGATGCGATGTTACGCTCGTTTTTGGGTAGCTTTGATTTCCGTGG
CGACCGTATCGATACCATAAGCGAGCTATTTTCTGGTGGTGAGCGTGCGCGCTTAACATTGGCTTTGATTGTTTGGCAAC
GTCCGAACGTGCTGGTACTCGATGAGCCAACCAACCATTTAGACCTACAAATGCGCCAAGCACTGACCATTGCTTTGCAG
GGCTTTGAAGGGGCAGTGGTATTGGTATCGCATGACCGTGAATTGATTGCCAACGTCTGTGATGAGCTGTTTTTGGTACA
TGATGGACAAATCGATGAGTTTGATGGTGATATAAGCGATTATGGTAAATGGCTTGCCGAAAAGCGTAAGCAGGAAAATT
CACAAGATAAAAATACCAGTAAGAAAAAAAGCAAAAAAGAGAGTAAGAAGTTTGTTTCACGTGAAACAGATGCTAATTCA
GTAGGTAGCCAAGCAAGCAAGCAAGTGGGTAAAGATGCGCAGCGCAAGCTGGCCGCTGAACAACGCAAATTAACAGCGCC
TATTCGCCGTGATATTGAAAATACAGAAAAGACCTTGGCAACAATTGATGGAAAGCTGCTGGTGTTAGAAGAAAAGCTGG
CGAATACGGATCTTTATGAAGAAAGTCGTAAGGCTGATTTGATGATACTGCTGAATGAGCAAACCGCGCTACAGCAGCAA
CATAGTCAACATGAAGAAAAATTGCTACTGGCAATGACAACCTTAGAAGAAATGGAAGCCAATATCGGCTAA

Upstream 100 bases:

>100_bases
TCGGTTAGGCGTTTGAAATAATAGCCGCCAGTAAACACGCCAGATAAGTGTTTTTCCTATTGCCTTATGTTTTATATTAC
CGCTGAGATGAAGAAATTAT

Downstream 100 bases:

>100_bases
TACCGTGAGGTTTTTATCAATTAGTTGTTAATCGAAACCAAGCGATAAAACTCAGTCATTAAAAAAGGGAAGGCTTACGC
CTTCCCTTTTTTTACTTTAT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MIEFKDVGVRRDGRELFAGASFQLHPGHKVGLTGNNGTGKSTLFALLLTRMGTGDTEVTLDKGEVNIPDSWHVAHMAQEV
GATTQTAIDYVLSGDEQWYEINATLNDLSSVSDEQIGVLHQQFDEIDGYRTPTKAAQIMAGLGFNTSQHELPVEGFSGGW
RMRLNLAKTLMSRADLMLLDEPTNHLDLDAILWLETWINAFTGLVIVISHDQTFLDNTVGHILHVEQQKITLYTGNYQQF
IRTRHERMAQQQQAFEKQEATKAHLDDFIRRFRAKASKAKQAQSRIKQLERMAELSPMMADNPFSFRFYEPANMSSPLIE
LTDADIGYSDTPLLYNANVQVTPDTRIGLLGMNGAGKSTLIKALVGELGVLKGSYNVSDTLKLGYFNQHQMDILDPKATP
IEMLRRLAGKTSDAMLRSFLGSFDFRGDRIDTISELFSGGERARLTLALIVWQRPNVLVLDEPTNHLDLQMRQALTIALQ
GFEGAVVLVSHDRELIANVCDELFLVHDGQIDEFDGDISDYGKWLAEKRKQENSQDKNTSKKKSKKESKKFVSRETDANS
VGSQASKQVGKDAQRKLAAEQRKLTAPIRRDIENTEKTLATIDGKLLVLEEKLANTDLYEESRKADLMILLNEQTALQQQ
HSQHEEKLLLAMTTLEEMEANIG

Sequences:

>Translated_663_residues
MIEFKDVGVRRDGRELFAGASFQLHPGHKVGLTGNNGTGKSTLFALLLTRMGTGDTEVTLDKGEVNIPDSWHVAHMAQEV
GATTQTAIDYVLSGDEQWYEINATLNDLSSVSDEQIGVLHQQFDEIDGYRTPTKAAQIMAGLGFNTSQHELPVEGFSGGW
RMRLNLAKTLMSRADLMLLDEPTNHLDLDAILWLETWINAFTGLVIVISHDQTFLDNTVGHILHVEQQKITLYTGNYQQF
IRTRHERMAQQQQAFEKQEATKAHLDDFIRRFRAKASKAKQAQSRIKQLERMAELSPMMADNPFSFRFYEPANMSSPLIE
LTDADIGYSDTPLLYNANVQVTPDTRIGLLGMNGAGKSTLIKALVGELGVLKGSYNVSDTLKLGYFNQHQMDILDPKATP
IEMLRRLAGKTSDAMLRSFLGSFDFRGDRIDTISELFSGGERARLTLALIVWQRPNVLVLDEPTNHLDLQMRQALTIALQ
GFEGAVVLVSHDRELIANVCDELFLVHDGQIDEFDGDISDYGKWLAEKRKQENSQDKNTSKKKSKKESKKFVSRETDANS
VGSQASKQVGKDAQRKLAAEQRKLTAPIRRDIENTEKTLATIDGKLLVLEEKLANTDLYEESRKADLMILLNEQTALQQQ
HSQHEEKLLLAMTTLEEMEANIG
>Mature_663_residues
MIEFKDVGVRRDGRELFAGASFQLHPGHKVGLTGNNGTGKSTLFALLLTRMGTGDTEVTLDKGEVNIPDSWHVAHMAQEV
GATTQTAIDYVLSGDEQWYEINATLNDLSSVSDEQIGVLHQQFDEIDGYRTPTKAAQIMAGLGFNTSQHELPVEGFSGGW
RMRLNLAKTLMSRADLMLLDEPTNHLDLDAILWLETWINAFTGLVIVISHDQTFLDNTVGHILHVEQQKITLYTGNYQQF
IRTRHERMAQQQQAFEKQEATKAHLDDFIRRFRAKASKAKQAQSRIKQLERMAELSPMMADNPFSFRFYEPANMSSPLIE
LTDADIGYSDTPLLYNANVQVTPDTRIGLLGMNGAGKSTLIKALVGELGVLKGSYNVSDTLKLGYFNQHQMDILDPKATP
IEMLRRLAGKTSDAMLRSFLGSFDFRGDRIDTISELFSGGERARLTLALIVWQRPNVLVLDEPTNHLDLQMRQALTIALQ
GFEGAVVLVSHDRELIANVCDELFLVHDGQIDEFDGDISDYGKWLAEKRKQENSQDKNTSKKKSKKESKKFVSRETDANS
VGSQASKQVGKDAQRKLAAEQRKLTAPIRRDIENTEKTLATIDGKLLVLEEKLANTDLYEESRKADLMILLNEQTALQQQ
HSQHEEKLLLAMTTLEEMEANIG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=531, Percent_Identity=35.0282485875706, Blast_Score=344, Evalue=1e-94,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=34.3339587242026, Blast_Score=306, Evalue=5e-83,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=34.3339587242026, Blast_Score=306, Evalue=6e-83,
Organism=Homo sapiens, GI10947135, Length=550, Percent_Identity=31.6363636363636, Blast_Score=253, Evalue=6e-67,
Organism=Homo sapiens, GI69354671, Length=550, Percent_Identity=31.6363636363636, Blast_Score=252, Evalue=6e-67,
Organism=Homo sapiens, GI105990541, Length=210, Percent_Identity=32.3809523809524, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789751, Length=659, Percent_Identity=47.040971168437, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1787041, Length=531, Percent_Identity=31.0734463276836, Blast_Score=290, Evalue=3e-79,
Organism=Escherichia coli, GI1787182, Length=644, Percent_Identity=27.0186335403727, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI2367384, Length=527, Percent_Identity=28.2732447817837, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1787758, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI145693107, Length=541, Percent_Identity=24.0295748613678, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788165, Length=194, Percent_Identity=29.3814432989691, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=207, Percent_Identity=28.9855072463768, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI48994997, Length=226, Percent_Identity=25.2212389380531, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=538, Percent_Identity=34.7583643122677, Blast_Score=321, Evalue=9e-88,
Organism=Caenorhabditis elegans, GI17555318, Length=545, Percent_Identity=31.9266055045872, Blast_Score=302, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI17559834, Length=558, Percent_Identity=30.2867383512545, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17556528, Length=196, Percent_Identity=27.0408163265306, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=544, Percent_Identity=34.375, Blast_Score=338, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6320874, Length=538, Percent_Identity=32.8996282527881, Blast_Score=289, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6325030, Length=395, Percent_Identity=27.0886075949367, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6323278, Length=382, Percent_Identity=27.4869109947644, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=387, Percent_Identity=25.3229974160207, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24666836, Length=522, Percent_Identity=36.7816091954023, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24642252, Length=540, Percent_Identity=34.0740740740741, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI18859989, Length=540, Percent_Identity=34.0740740740741, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24641342, Length=541, Percent_Identity=32.3475046210721, Blast_Score=292, Evalue=5e-79,
Organism=Drosophila melanogaster, GI116007184, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221500365, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 74340; Mature: 74340

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFKDVGVRRDGRELFAGASFQLHPGHKVGLTGNNGTGKSTLFALLLTRMGTGDTEVTL
CCCCCCCCCCCCCHHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEE
DKGEVNIPDSWHVAHMAQEVGATTQTAIDYVLSGDEQWYEINATLNDLSSVSDEQIGVLH
ECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCHHHHHHCCHHHHHHHH
QQFDEIDGYRTPTKAAQIMAGLGFNTSQHELPVEGFSGGWRMRLNLAKTLMSRADLMLLD
HHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEE
EPTNHLDLDAILWLETWINAFTGLVIVISHDQTFLDNTVGHILHVEQQKITLYTGNYQQF
CCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHEEEECCEEEEEECCHHHH
IRTRHERMAQQQQAFEKQEATKAHLDDFIRRFRAKASKAKQAQSRIKQLERMAELSPMMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
DNPFSFRFYEPANMSSPLIELTDADIGYSDTPLLYNANVQVTPDTRIGLLGMNGAGKSTL
CCCCEEEEECCCCCCCCEEEEECCCCCCCCCCEEEECEEEECCCCEEEEEECCCCCHHHH
IKALVGELGVLKGSYNVSDTLKLGYFNQHQMDILDPKATPIEMLRRLAGKTSDAMLRSFL
HHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
GSFDFRGDRIDTISELFSGGERARLTLALIVWQRPNVLVLDEPTNHLDLQMRQALTIALQ
HCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHEE
GFEGAVVLVSHDRELIANVCDELFLVHDGQIDEFDGDISDYGKWLAEKRKQENSQDKNTS
CCCCEEEEEECCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
KKKSKKESKKFVSRETDANSVGSQASKQVGKDAQRKLAAEQRKLTAPIRRDIENTEKTLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIDGKLLVLEEKLANTDLYEESRKADLMILLNEQTALQQQHSQHEEKLLLAMTTLEEMEA
HCCCEEEEEEHHHCCCCHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NIG
CCC
>Mature Secondary Structure
MIEFKDVGVRRDGRELFAGASFQLHPGHKVGLTGNNGTGKSTLFALLLTRMGTGDTEVTL
CCCCCCCCCCCCCHHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEE
DKGEVNIPDSWHVAHMAQEVGATTQTAIDYVLSGDEQWYEINATLNDLSSVSDEQIGVLH
ECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCHHHHHHCCHHHHHHHH
QQFDEIDGYRTPTKAAQIMAGLGFNTSQHELPVEGFSGGWRMRLNLAKTLMSRADLMLLD
HHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEE
EPTNHLDLDAILWLETWINAFTGLVIVISHDQTFLDNTVGHILHVEQQKITLYTGNYQQF
CCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHEEEECCEEEEEECCHHHH
IRTRHERMAQQQQAFEKQEATKAHLDDFIRRFRAKASKAKQAQSRIKQLERMAELSPMMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
DNPFSFRFYEPANMSSPLIELTDADIGYSDTPLLYNANVQVTPDTRIGLLGMNGAGKSTL
CCCCEEEEECCCCCCCCEEEEECCCCCCCCCCEEEECEEEECCCCEEEEEECCCCCHHHH
IKALVGELGVLKGSYNVSDTLKLGYFNQHQMDILDPKATPIEMLRRLAGKTSDAMLRSFL
HHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
GSFDFRGDRIDTISELFSGGERARLTLALIVWQRPNVLVLDEPTNHLDLQMRQALTIALQ
HCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHEE
GFEGAVVLVSHDRELIANVCDELFLVHDGQIDEFDGDISDYGKWLAEKRKQENSQDKNTS
CCCCEEEEEECCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
KKKSKKESKKFVSRETDANSVGSQASKQVGKDAQRKLAAEQRKLTAPIRRDIENTEKTLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIDGKLLVLEEKLANTDLYEESRKADLMILLNEQTALQQQHSQHEEKLLLAMTTLEEMEA
HCCCEEEEEEHHHCCCCHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NIG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]