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The map label for this gene is thrS

Identifier: 92113922

GI number: 92113922

Start: 2046100

End: 2047998

Strand: Direct

Name: thrS

Synonym: Csal_1799

Alternate gene names: 92113922

Gene position: 2046100-2047998 (Clockwise)

Preceding gene: 92113921

Following gene: 92113923

Centisome position: 55.35

GC content: 60.45

Gene sequence:

>1899_bases
ATGCCCATCGTGACCCTGCCTGATGGCAGTCAGAAGACTTTCGATTCCCCCATCACCGTCATGCAGCTCGCCGAGTCGAT
CGGTACCGGGCTGGCCAAGGCTTGCGTGGCCGGCAAGATCGACGGCGTGCCCGTCGATACCGCCGACGTGATCGAGCACG
ATGCCGAAGTGAGCATCCTCACGCCGCGCGATCAGGAAGGGCTGGAGATCATTCGCCACTCGTGTGCCCATCTCGTCGGT
CATGCCGTCAAGCAGCTTTATCCCGATGCCAAGATGGCGATCGGGCCGGTCATCGACGATGGCTTCTACTACGATATCGA
TTTCGGCCAGTCGGTCTCGCCGGAGGATCTCGAGGCCATCGAGAAACGCATGAAAGTGTTGATCGATCATGAGTACGAGG
TCATCCGCGAGTACGTCACGAAAGAGCAGGCCCTGGCGACGTTCATCGACCGCGACGAGCCATACAAGCAGGAAATCGTC
GAGGGCATCGCGGATGGCGAGACGGTGCGTCTCTACCATCACGAAGAATACATCGACATGTGCCGCGGGCCGCACGTGCC
CAACACCCGTCACCTCAAGGCGTTCAAGCTGACCAAGCTGGCAGGGGCCTATTGGCGTGGCGATGCCAACAAGCCGATGC
TCACTCGCATCTACGGGACGGCCTGGGCGGACAAGAAGGCGCTGAAGACCTATCTCAAGCGCCTGGAGGAAGCGGAAAAG
CGCGATCATCGCAAGCTGGCCCGCAAGCTCGACTTCTTTCACATGCAGGAAGAAGCGCCCGGGATGGTGTTCTGGCACCC
GCGCGGCTGGACGCTGTGGCAGACCGTCGAGCAGTACATGCGCGGCGTCTACAAGGACAGCGGCTATCAGGAGATTCGCT
GCCCGCAGATCATGGATGTGTCGCTATGGCAGAAGTCCGGCCATTGGGACAACTATGCCGAGAACATGTTCTTCACTGAA
TCGGAAAAGCGCGAATATGCGCTCAAGCCGATGAACTGTCCCGGGCATGTACAAGTCTTCAATTCCGGGCTGCGCAGCTA
TCGCGAACTGCCGGTGCGCTATGGCGAATTCGGAGGGTGTCACCGCAACGAGCCCTCGGGCGCCTTGCACGGCATCATGC
GGGTACGTGCGTTCACTCAGGACGACGGTCACGTGTTCTGCACCGAGGAGCAGATCGAGCCGGAGGTGACGGCATTCCAT
CGGCAGGCCCTGGCGGTCTATCGTGATTTCGGCTTCGACGACATCGCCGTCAAGATCGCCCTGCGGCCCGAGAAGCGTCT
GGGCAGCGACGACAACTGGGATCGCGCCGAAGAGGCCTTGCGCAACGCCCTGAGCCGCTGTGACGTCGAATGGGAAGAGT
TGCCCGGTGAAGGCGCCTTCTATGGCCCCAAGATCGAGTATCACATGCGCGACTGCCTGGGCCGCGAGTGGCAGGTGGGT
ACCATGCAGGTGGATTTCATGATGCCGACCCGGCTCGGCGCGCAGTACGTGGCCGAGGACGGTTCGCGGCAGGCGCCGGT
CATGCTGCACCGCGCCATCGTGGGGTCCATGGAACGCTTCATCGGTATCCTCATCGAACACTATGCGGGATCCATGCCCT
TGTGGCTTTCACCGCTCCAGGCCGTGGTGCTCAACATCACCGATGCCCAGCGGGAATACGCCGAATCCGTGACGCAGCGT
TTGCAGAAATCCGGTCTGCGTGTCAAGACGGACTTGAGGAATGAGAAGATCGGCTTTAAAATCCGGGAACATACGTTGCA
AAAGATCCCCTATCTTCTCGTTGTAGGTGACAAAGAAGTCGAGGCGGGTGCGGTTGCCGTCCGTACGCGTAGCGGAGAGG
ACCTGGGCTCGCTATCGGTGGACGCCTTGATTGCGCGTCTGCAGGAAGAAGGGGTATAA

Upstream 100 bases:

>100_bases
CTCGTGCGAGCGGCAGCGTCAATGTCGCCGAGCGCGCCAATCATTTTCGTCGTTCATGTGGTCCCTGGTATGGGCCACCA
CTGAAGATAAGGGATGTTAC

Downstream 100 bases:

>100_bases
AGAACGTCAATCGATAGAACGGAGACGTAACGATCAAGCGGAATAACCAGCGCGGGCGCCCTCAAGAGAAGCGCCCCCCA
ATGAACGACCGTATTCGTGT

Product: threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MPIVTLPDGSQKTFDSPITVMQLAESIGTGLAKACVAGKIDGVPVDTADVIEHDAEVSILTPRDQEGLEIIRHSCAHLVG
HAVKQLYPDAKMAIGPVIDDGFYYDIDFGQSVSPEDLEAIEKRMKVLIDHEYEVIREYVTKEQALATFIDRDEPYKQEIV
EGIADGETVRLYHHEEYIDMCRGPHVPNTRHLKAFKLTKLAGAYWRGDANKPMLTRIYGTAWADKKALKTYLKRLEEAEK
RDHRKLARKLDFFHMQEEAPGMVFWHPRGWTLWQTVEQYMRGVYKDSGYQEIRCPQIMDVSLWQKSGHWDNYAENMFFTE
SEKREYALKPMNCPGHVQVFNSGLRSYRELPVRYGEFGGCHRNEPSGALHGIMRVRAFTQDDGHVFCTEEQIEPEVTAFH
RQALAVYRDFGFDDIAVKIALRPEKRLGSDDNWDRAEEALRNALSRCDVEWEELPGEGAFYGPKIEYHMRDCLGREWQVG
TMQVDFMMPTRLGAQYVAEDGSRQAPVMLHRAIVGSMERFIGILIEHYAGSMPLWLSPLQAVVLNITDAQREYAESVTQR
LQKSGLRVKTDLRNEKIGFKIREHTLQKIPYLLVVGDKEVEAGAVAVRTRSGEDLGSLSVDALIARLQEEGV

Sequences:

>Translated_632_residues
MPIVTLPDGSQKTFDSPITVMQLAESIGTGLAKACVAGKIDGVPVDTADVIEHDAEVSILTPRDQEGLEIIRHSCAHLVG
HAVKQLYPDAKMAIGPVIDDGFYYDIDFGQSVSPEDLEAIEKRMKVLIDHEYEVIREYVTKEQALATFIDRDEPYKQEIV
EGIADGETVRLYHHEEYIDMCRGPHVPNTRHLKAFKLTKLAGAYWRGDANKPMLTRIYGTAWADKKALKTYLKRLEEAEK
RDHRKLARKLDFFHMQEEAPGMVFWHPRGWTLWQTVEQYMRGVYKDSGYQEIRCPQIMDVSLWQKSGHWDNYAENMFFTE
SEKREYALKPMNCPGHVQVFNSGLRSYRELPVRYGEFGGCHRNEPSGALHGIMRVRAFTQDDGHVFCTEEQIEPEVTAFH
RQALAVYRDFGFDDIAVKIALRPEKRLGSDDNWDRAEEALRNALSRCDVEWEELPGEGAFYGPKIEYHMRDCLGREWQVG
TMQVDFMMPTRLGAQYVAEDGSRQAPVMLHRAIVGSMERFIGILIEHYAGSMPLWLSPLQAVVLNITDAQREYAESVTQR
LQKSGLRVKTDLRNEKIGFKIREHTLQKIPYLLVVGDKEVEAGAVAVRTRSGEDLGSLSVDALIARLQEEGV
>Mature_631_residues
PIVTLPDGSQKTFDSPITVMQLAESIGTGLAKACVAGKIDGVPVDTADVIEHDAEVSILTPRDQEGLEIIRHSCAHLVGH
AVKQLYPDAKMAIGPVIDDGFYYDIDFGQSVSPEDLEAIEKRMKVLIDHEYEVIREYVTKEQALATFIDRDEPYKQEIVE
GIADGETVRLYHHEEYIDMCRGPHVPNTRHLKAFKLTKLAGAYWRGDANKPMLTRIYGTAWADKKALKTYLKRLEEAEKR
DHRKLARKLDFFHMQEEAPGMVFWHPRGWTLWQTVEQYMRGVYKDSGYQEIRCPQIMDVSLWQKSGHWDNYAENMFFTES
EKREYALKPMNCPGHVQVFNSGLRSYRELPVRYGEFGGCHRNEPSGALHGIMRVRAFTQDDGHVFCTEEQIEPEVTAFHR
QALAVYRDFGFDDIAVKIALRPEKRLGSDDNWDRAEEALRNALSRCDVEWEELPGEGAFYGPKIEYHMRDCLGREWQVGT
MQVDFMMPTRLGAQYVAEDGSRQAPVMLHRAIVGSMERFIGILIEHYAGSMPLWLSPLQAVVLNITDAQREYAESVTQRL
QKSGLRVKTDLRNEKIGFKIREHTLQKIPYLLVVGDKEVEAGAVAVRTRSGEDLGSLSVDALIARLQEEGV

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI38202255, Length=633, Percent_Identity=40.7582938388626, Blast_Score=473, Evalue=1e-133,
Organism=Homo sapiens, GI38570111, Length=613, Percent_Identity=38.6623164763458, Blast_Score=447, Evalue=1e-125,
Organism=Homo sapiens, GI20070344, Length=647, Percent_Identity=34.1576506955178, Blast_Score=390, Evalue=1e-108,
Organism=Escherichia coli, GI1788013, Length=631, Percent_Identity=61.3312202852615, Blast_Score=847, Evalue=0.0,
Organism=Escherichia coli, GI1786392, Length=162, Percent_Identity=26.5432098765432, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71984192, Length=638, Percent_Identity=38.0877742946708, Blast_Score=461, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI71984184, Length=638, Percent_Identity=38.0877742946708, Blast_Score=461, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6322112, Length=627, Percent_Identity=38.4370015948963, Blast_Score=441, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6322654, Length=397, Percent_Identity=36.5239294710327, Blast_Score=283, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24583842, Length=632, Percent_Identity=40.8227848101266, Blast_Score=487, Evalue=1e-137,
Organism=Drosophila melanogaster, GI28574141, Length=632, Percent_Identity=40.8227848101266, Blast_Score=487, Evalue=1e-137,
Organism=Drosophila melanogaster, GI24583839, Length=632, Percent_Identity=40.8227848101266, Blast_Score=487, Evalue=1e-137,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYT_CHRSD (Q1QWK7)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573850.1
- ProteinModelPortal:   Q1QWK7
- SMR:   Q1QWK7
- STRING:   Q1QWK7
- GeneID:   4028599
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1799
- NMPDR:   fig|290398.4.peg.3061
- eggNOG:   COG0441
- HOGENOM:   HBG352811
- OMA:   GFEYEVE
- BioCyc:   CSAL290398:CSAL_1799-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00184_B
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947
- Gene3D:   G3DSA:3.40.50.800
- Gene3D:   G3DSA:3.10.20.30
- PRINTS:   PR01047
- SMART:   SM00863
- TIGRFAMs:   TIGR00418

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD; SSF52954 Anticodon_bd; SSF81271 TGS-like; SSF55186 Thr/Ala-tRNA-synth_IIc_edit

EC number: =6.1.1.3

Molecular weight: Translated: 72070; Mature: 71939

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIVTLPDGSQKTFDSPITVMQLAESIGTGLAKACVAGKIDGVPVDTADVIEHDAEVSIL
CCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEE
TPRDQEGLEIIRHSCAHLVGHAVKQLYPDAKMAIGPVIDDGFYYDIDFGQSVSPEDLEAI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCEECCCEEEEECCCCCCCHHHHHHH
EKRMKVLIDHEYEVIREYVTKEQALATFIDRDEPYKQEIVEGIADGETVRLYHHEEYIDM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECHHHHHH
CRGPHVPNTRHLKAFKLTKLAGAYWRGDANKPMLTRIYGTAWADKKALKTYLKRLEEAEK
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHCCHHCCHHHHHHHHHHHHHHHH
RDHRKLARKLDFFHMQEEAPGMVFWHPRGWTLWQTVEQYMRGVYKDSGYQEIRCPQIMDV
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEH
SLWQKSGHWDNYAENMFFTESEKREYALKPMNCPGHVQVFNSGLRSYRELPVRYGEFGGC
HHHHCCCCCCCHHCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
HRNEPSGALHGIMRVRAFTQDDGHVFCTEEQIEPEVTAFHRQALAVYRDFGFDDIAVKIA
CCCCCCHHHHHHHHHHHEECCCCCEEEEHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
LRPEKRLGSDDNWDRAEEALRNALSRCDVEWEELPGEGAFYGPKIEYHMRDCLGREWQVG
ECCHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEHHHHHHHCCCCEEEC
TMQVDFMMPTRLGAQYVAEDGSRQAPVMLHRAIVGSMERFIGILIEHYAGSMPLWLSPLQ
EEEEEEECCHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AVVLNITDAQREYAESVTQRLQKSGLRVKTDLRNEKIGFKIREHTLQKIPYLLVVGDKEV
HHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCCC
EAGAVAVRTRSGEDLGSLSVDALIARLQEEGV
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIVTLPDGSQKTFDSPITVMQLAESIGTGLAKACVAGKIDGVPVDTADVIEHDAEVSIL
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEE
TPRDQEGLEIIRHSCAHLVGHAVKQLYPDAKMAIGPVIDDGFYYDIDFGQSVSPEDLEAI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCEECCCEEEEECCCCCCCHHHHHHH
EKRMKVLIDHEYEVIREYVTKEQALATFIDRDEPYKQEIVEGIADGETVRLYHHEEYIDM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECHHHHHH
CRGPHVPNTRHLKAFKLTKLAGAYWRGDANKPMLTRIYGTAWADKKALKTYLKRLEEAEK
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHCCHHCCHHHHHHHHHHHHHHHH
RDHRKLARKLDFFHMQEEAPGMVFWHPRGWTLWQTVEQYMRGVYKDSGYQEIRCPQIMDV
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEH
SLWQKSGHWDNYAENMFFTESEKREYALKPMNCPGHVQVFNSGLRSYRELPVRYGEFGGC
HHHHCCCCCCCHHCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
HRNEPSGALHGIMRVRAFTQDDGHVFCTEEQIEPEVTAFHRQALAVYRDFGFDDIAVKIA
CCCCCCHHHHHHHHHHHEECCCCCEEEEHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
LRPEKRLGSDDNWDRAEEALRNALSRCDVEWEELPGEGAFYGPKIEYHMRDCLGREWQVG
ECCHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEHHHHHHHCCCCEEEC
TMQVDFMMPTRLGAQYVAEDGSRQAPVMLHRAIVGSMERFIGILIEHYAGSMPLWLSPLQ
EEEEEEECCHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AVVLNITDAQREYAESVTQRLQKSGLRVKTDLRNEKIGFKIREHTLQKIPYLLVVGDKEV
HHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCCC
EAGAVAVRTRSGEDLGSLSVDALIARLQEEGV
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA