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The map label for this gene is yfkJ [H]

Identifier: 92113714

GI number: 92113714

Start: 1809960

End: 1810448

Strand: Direct

Name: yfkJ [H]

Synonym: Csal_1590

Alternate gene names: 92113714

Gene position: 1809960-1810448 (Clockwise)

Preceding gene: 92113713

Following gene: 92113715

Centisome position: 48.96

GC content: 70.55

Gene sequence:

>489_bases
ATGATACGCATTCTGTTCGTTTGCCTGGGCAACATCTGCCGCTCGCCGACCGCCGAGGGCATCGTGCGATCCCGCCTTCA
GGCGGCGGGGCTGGCCGACGAGGTGGCGCTCGACTCGTGCGGTACCGGGCGCTGGCACGTCGGGGAGCCGCCGGATCCGC
GCGCCCAGCAGGAAGCCCGCGCACGCGGCATCGACATCGCCTCGCTGCGCGCGCGCCAGCTCTCGGTGGAGGACTTTCGG
CGCTTCGACTACCTGCTGGCCATGGACGCGGAGAACCTGGCCCATATGCAGCGCATGGCGCCGGCGGACTGCCAGGCGCA
CGTCGGTCTGCTGCTGGACTTCGCCGGCGAGCGGGGACGCTCGGTGCCGGATCCCTACTACGGGACGGACGACGGCTTCG
CCGAGGTGTTCGCCCTGATCGAGCAGGCGGCGGATGGGCTCATCGATGCCTGCCGGCAGCGCCTGGAGCGTGGCGATGCA
CATCGCTGA

Upstream 100 bases:

>100_bases
TCCAGGTGGCGCTGGCCGCCGAGGCGCATCCCGCGGGCGTCGACACCGAAGCGGATCTCGCGCGGGTTCGTCGCTTGATC
GCCGAGGGGGAAGGGGCGGC

Downstream 100 bases:

>100_bases
CGACGCGCCCCTCGACAATACCCTGGGGTTGCCGTGCCGGGCGGCGCGCCTGGTCGCGGCGACCACCCGCGATGACATCC
GTCAGGCGCTGGCCATGGCC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MIRILFVCLGNICRSPTAEGIVRSRLQAAGLADEVALDSCGTGRWHVGEPPDPRAQQEARARGIDIASLRARQLSVEDFR
RFDYLLAMDAENLAHMQRMAPADCQAHVGLLLDFAGERGRSVPDPYYGTDDGFAEVFALIEQAADGLIDACRQRLERGDA
HR

Sequences:

>Translated_162_residues
MIRILFVCLGNICRSPTAEGIVRSRLQAAGLADEVALDSCGTGRWHVGEPPDPRAQQEARARGIDIASLRARQLSVEDFR
RFDYLLAMDAENLAHMQRMAPADCQAHVGLLLDFAGERGRSVPDPYYGTDDGFAEVFALIEQAADGLIDACRQRLERGDA
HR
>Mature_162_residues
MIRILFVCLGNICRSPTAEGIVRSRLQAAGLADEVALDSCGTGRWHVGEPPDPRAQQEARARGIDIASLRARQLSVEDFR
RFDYLLAMDAENLAHMQRMAPADCQAHVGLLLDFAGERGRSVPDPYYGTDDGFAEVFALIEQAADGLIDACRQRLERGDA
HR

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=157, Percent_Identity=38.2165605095541, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI4757714, Length=157, Percent_Identity=36.3057324840764, Blast_Score=109, Evalue=8e-25,
Organism=Escherichia coli, GI87081812, Length=142, Percent_Identity=32.3943661971831, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788375, Length=141, Percent_Identity=34.0425531914894, Blast_Score=71, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325330, Length=143, Percent_Identity=33.5664335664336, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI78706764, Length=126, Percent_Identity=40.4761904761905, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI78706766, Length=126, Percent_Identity=40.4761904761905, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI78706768, Length=126, Percent_Identity=40.4761904761905, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI78706770, Length=136, Percent_Identity=40.4411764705882, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI78706772, Length=136, Percent_Identity=40.4411764705882, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI78711846, Length=130, Percent_Identity=36.1538461538462, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648069, Length=87, Percent_Identity=42.5287356321839, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17852; Mature: 17852

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRILFVCLGNICRSPTAEGIVRSRLQAAGLADEVALDSCGTGRWHVGEPPDPRAQQEAR
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
ARGIDIASLRARQLSVEDFRRFDYLLAMDAENLAHMQRMAPADCQAHVGLLLDFAGERGR
HHCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
SVPDPYYGTDDGFAEVFALIEQAADGLIDACRQRLERGDAHR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIRILFVCLGNICRSPTAEGIVRSRLQAAGLADEVALDSCGTGRWHVGEPPDPRAQQEAR
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
ARGIDIASLRARQLSVEDFRRFDYLLAMDAENLAHMQRMAPADCQAHVGLLLDFAGERGR
HHCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
SVPDPYYGTDDGFAEVFALIEQAADGLIDACRQRLERGDAHR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]