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The map label for this gene is murB [H]

Identifier: 92113715

GI number: 92113715

Start: 1810435

End: 1811436

Strand: Direct

Name: murB [H]

Synonym: Csal_1591

Alternate gene names: 92113715

Gene position: 1810435-1811436 (Clockwise)

Preceding gene: 92113714

Following gene: 92113717

Centisome position: 48.98

GC content: 68.76

Gene sequence:

>1002_bases
ATGCACATCGCTGACGACGCGCCCCTCGACAATACCCTGGGGTTGCCGTGCCGGGCGGCGCGCCTGGTCGCGGCGACCAC
CCGCGATGACATCCGTCAGGCGCTGGCCATGGCCCGTCACGACGAGGCGCCGTTGCAGGTGGTGGGCGGCGCGAGCAACG
TCATCCTGCCGGCGCGTCTGCCGGGCGTGACGTTGCAGCTGGCATGCGACGACTGGTGGTGGCACGCGGTCGACGAGCAG
ACGGTGCAGGTGCATGCCGAGGCCGGCCTGTCGTGGCACGAGCTGGTAACCGCCTGTGTCGAGAAAGGCTGGTGGGGCAT
CGAGAACCTGGCCTTGATCCCGGGGCAGGTGGGGGCCGCGCCGATCCAGAACATCGGCGCCTACGGCGTCGAGCTGGCCG
ATGTCCTGGAGGCGGTGCATGTCATGTATCGCGAGGATGGTCGCGAGGAGGTGCTGCCCCGCGAGGCCTGCGACTTCGCC
TATCGCGACAGTATCTTCAAGCGCTCCCTGGCGGGGCGCGTGGTGGTGACGAAGATCGTGCTGCGCTTGTCGCGCCGTCC
CGCGCCGCGTCTCGGCTATGGCGATCTCGCCCAGCGCGTCTCGACGTCACCCACGCCGCACGAGATCTACACGGCAGTGT
GCGCCATACGGCGCGAGAAGCTGCCCGACCCCGCGGTGCTGGGCAATGCCGGCAGCTTCTTCACCAATCCCGTGGTCGAG
GCCTCGCATGCCGAGCGCTTGTTGCAGGAATTCCCCGACATGCCGCATTTCCCCCAGCCCGATGGCCGCATCAAGCTCGC
GGCGGGCTGGCTGATCGACCGCTGCGGCTTCAAGGGACAGCGTTGCGGCGCCTTCGGGATGCATGAGCGTCAGGCGTTGG
TGCTGGTGCACTTCGGTGGCGGCGACAGGCCGGCCTTGCTGGCCTGGGCCGAGCGCATTCGCGATGCCGTGCAGCAGCGC
TTCAATGTGGTCCTGGAACGCGAGCCGCGTCTGCTGGGGTAG

Upstream 100 bases:

>100_bases
TACTACGGGACGGACGACGGCTTCGCCGAGGTGTTCGCCCTGATCGAGCAGGCGGCGGATGGGCTCATCGATGCCTGCCG
GCAGCGCCTGGAGCGTGGCG

Downstream 100 bases:

>100_bases
GGCGCTGCGGCACTCGTCGGCGTGGTGGGCACCCCACAGGAAGGCACCATGAAAAACGCCTGAAGGATCATCCTTCAGGC
GTTTTCGTGTCGCGGTATGG

Product: UDP-N-acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MHIADDAPLDNTLGLPCRAARLVAATTRDDIRQALAMARHDEAPLQVVGGASNVILPARLPGVTLQLACDDWWWHAVDEQ
TVQVHAEAGLSWHELVTACVEKGWWGIENLALIPGQVGAAPIQNIGAYGVELADVLEAVHVMYREDGREEVLPREACDFA
YRDSIFKRSLAGRVVVTKIVLRLSRRPAPRLGYGDLAQRVSTSPTPHEIYTAVCAIRREKLPDPAVLGNAGSFFTNPVVE
ASHAERLLQEFPDMPHFPQPDGRIKLAAGWLIDRCGFKGQRCGAFGMHERQALVLVHFGGGDRPALLAWAERIRDAVQQR
FNVVLEREPRLLG

Sequences:

>Translated_333_residues
MHIADDAPLDNTLGLPCRAARLVAATTRDDIRQALAMARHDEAPLQVVGGASNVILPARLPGVTLQLACDDWWWHAVDEQ
TVQVHAEAGLSWHELVTACVEKGWWGIENLALIPGQVGAAPIQNIGAYGVELADVLEAVHVMYREDGREEVLPREACDFA
YRDSIFKRSLAGRVVVTKIVLRLSRRPAPRLGYGDLAQRVSTSPTPHEIYTAVCAIRREKLPDPAVLGNAGSFFTNPVVE
ASHAERLLQEFPDMPHFPQPDGRIKLAAGWLIDRCGFKGQRCGAFGMHERQALVLVHFGGGDRPALLAWAERIRDAVQQR
FNVVLEREPRLLG
>Mature_333_residues
MHIADDAPLDNTLGLPCRAARLVAATTRDDIRQALAMARHDEAPLQVVGGASNVILPARLPGVTLQLACDDWWWHAVDEQ
TVQVHAEAGLSWHELVTACVEKGWWGIENLALIPGQVGAAPIQNIGAYGVELADVLEAVHVMYREDGREEVLPREACDFA
YRDSIFKRSLAGRVVVTKIVLRLSRRPAPRLGYGDLAQRVSTSPTPHEIYTAVCAIRREKLPDPAVLGNAGSFFTNPVVE
ASHAERLLQEFPDMPHFPQPDGRIKLAAGWLIDRCGFKGQRCGAFGMHERQALVLVHFGGGDRPALLAWAERIRDAVQQR
FNVVLEREPRLLG

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=332, Percent_Identity=40.9638554216867, Blast_Score=251, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 36722; Mature: 36722

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00205 TRANSFERRIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIADDAPLDNTLGLPCRAARLVAATTRDDIRQALAMARHDEAPLQVVGGASNVILPARL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCC
PGVTLQLACDDWWWHAVDEQTVQVHAEAGLSWHELVTACVEKGWWGIENLALIPGQVGAA
CCEEEEEEECCCHHHCCCCCEEEEEHHCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCC
PIQNIGAYGVELADVLEAVHVMYREDGREEVLPREACDFAYRDSIFKRSLAGRVVVTKIV
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
LRLSRRPAPRLGYGDLAQRVSTSPTPHEIYTAVCAIRREKLPDPAVLGNAGSFFTNPVVE
HHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCHHCCCCCC
ASHAERLLQEFPDMPHFPQPDGRIKLAAGWLIDRCGFKGQRCGAFGMHERQALVLVHFGG
HHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCCCEEEEEEECC
GDRPALLAWAERIRDAVQQRFNVVLEREPRLLG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHIADDAPLDNTLGLPCRAARLVAATTRDDIRQALAMARHDEAPLQVVGGASNVILPARL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCC
PGVTLQLACDDWWWHAVDEQTVQVHAEAGLSWHELVTACVEKGWWGIENLALIPGQVGAA
CCEEEEEEECCCHHHCCCCCEEEEEHHCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCC
PIQNIGAYGVELADVLEAVHVMYREDGREEVLPREACDFAYRDSIFKRSLAGRVVVTKIV
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
LRLSRRPAPRLGYGDLAQRVSTSPTPHEIYTAVCAIRREKLPDPAVLGNAGSFFTNPVVE
HHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCHHCCCCCC
ASHAERLLQEFPDMPHFPQPDGRIKLAAGWLIDRCGFKGQRCGAFGMHERQALVLVHFGG
HHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCCCEEEEEEECC
GDRPALLAWAERIRDAVQQRFNVVLEREPRLLG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]