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The map label for this gene is kdsB

Identifier: 92113713

GI number: 92113713

Start: 1809190

End: 1809963

Strand: Direct

Name: kdsB

Synonym: Csal_1589

Alternate gene names: 92113713

Gene position: 1809190-1809963 (Clockwise)

Preceding gene: 92113712

Following gene: 92113714

Centisome position: 48.94

GC content: 67.96

Gene sequence:

>774_bases
ATGAGTGATGTCGTGGTCGTGATACCGGCACGCTATGGCGCCTCGCGCCTGCCGGGCAAGCCCTTGCTGGACCTCCACGG
CGAACCGATGATCGCCCGCGTCTGGCAGCGCGCGTGTAAGAGTGACGCGACGCGGGTGGTGATCGCCACCGATGACGAAC
GCATCGAGGCGGCCATGCAGCCGTACGGCGCGGACGTCATGCTGACCGCGCCCGATCATCCCTCGGGCACCGACCGCCTG
GCGGAGGTCGCGGCCCGGCTCGAGCTAGATGCCGACACCATCGTGGTCAACGTGCAGGGGGACGAGCCCCTGTTGCCGCC
GGCGTTGATCGACCAGGTGGTACGCCGGCTGGCCGACGACACCACGGCCTCCATTGCCACCCTGGCCGAGCCCATCGGCG
ACGTGGAAACCTTGTTCAATCCCAACGTGGTCAAGGTCGTGCGCGACCTGCACGGGCGCGCCCTGTATTTCTCGCGGGCG
CCGGTGCCCTGGGATCGGGAGCATTTCGCCACGCGTCCCGATTGCCTGGCGACCGATGCCTGGCTGCGTCATATCGGCCT
TTACGCCTATCGTGCCGGTTTTCTGGCGGCGTATGTCGACTGGCTGCCGTCGCCGCTCGAGCAGCTGGAACAGCTCGAAC
AGTTGCGTGCCATGCACCATGGGCACCGAATCCAGGTGGCGCTGGCCGCCGAGGCGCATCCCGCGGGCGTCGACACCGAA
GCGGATCTCGCGCGGGTTCGTCGCTTGATCGCCGAGGGGGAAGGGGCGGCATGA

Upstream 100 bases:

>100_bases
TCGAGGACGAGATTCCGGTGATGCTCGAAGAGCAGGCGCGCCACATGGATGCCGACGAAAAGCTGGGCAAGGCGCCGGGC
GAGGCGCGGGATGCCACCTC

Downstream 100 bases:

>100_bases
TACGCATTCTGTTCGTTTGCCTGGGCAACATCTGCCGCTCGCCGACCGCCGAGGGCATCGTGCGATCCCGCCTTCAGGCG
GCGGGGCTGGCCGACGAGGT

Product: 3-deoxy-D-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSDVVVVIPARYGASRLPGKPLLDLHGEPMIARVWQRACKSDATRVVIATDDERIEAAMQPYGADVMLTAPDHPSGTDRL
AEVAARLELDADTIVVNVQGDEPLLPPALIDQVVRRLADDTTASIATLAEPIGDVETLFNPNVVKVVRDLHGRALYFSRA
PVPWDREHFATRPDCLATDAWLRHIGLYAYRAGFLAAYVDWLPSPLEQLEQLEQLRAMHHGHRIQVALAAEAHPAGVDTE
ADLARVRRLIAEGEGAA

Sequences:

>Translated_257_residues
MSDVVVVIPARYGASRLPGKPLLDLHGEPMIARVWQRACKSDATRVVIATDDERIEAAMQPYGADVMLTAPDHPSGTDRL
AEVAARLELDADTIVVNVQGDEPLLPPALIDQVVRRLADDTTASIATLAEPIGDVETLFNPNVVKVVRDLHGRALYFSRA
PVPWDREHFATRPDCLATDAWLRHIGLYAYRAGFLAAYVDWLPSPLEQLEQLEQLRAMHHGHRIQVALAAEAHPAGVDTE
ADLARVRRLIAEGEGAA
>Mature_256_residues
SDVVVVIPARYGASRLPGKPLLDLHGEPMIARVWQRACKSDATRVVIATDDERIEAAMQPYGADVMLTAPDHPSGTDRLA
EVAARLELDADTIVVNVQGDEPLLPPALIDQVVRRLADDTTASIATLAEPIGDVETLFNPNVVKVVRDLHGRALYFSRAP
VPWDREHFATRPDCLATDAWLRHIGLYAYRAGFLAAYVDWLPSPLEQLEQLEQLRAMHHGHRIQVALAAEAHPAGVDTEA
DLARVRRLIAEGEGAA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=243, Percent_Identity=53.0864197530864, Blast_Score=258, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_CHRSD (Q1QX66)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573641.1
- ProteinModelPortal:   Q1QX66
- SMR:   Q1QX66
- STRING:   Q1QX66
- GeneID:   4027608
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1589
- NMPDR:   fig|290398.4.peg.3044
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- BioCyc:   CSAL290398:CSAL_1589-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 28147; Mature: 28016

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVVVVIPARYGASRLPGKPLLDLHGEPMIARVWQRACKSDATRVVIATDDERIEAAMQ
CCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHC
PYGADVMLTAPDHPSGTDRLAEVAARLELDADTIVVNVQGDEPLLPPALIDQVVRRLADD
CCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCC
TTASIATLAEPIGDVETLFNPNVVKVVRDLHGRALYFSRAPVPWDREHFATRPDCLATDA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCHHHHHH
WLRHIGLYAYRAGFLAAYVDWLPSPLEQLEQLEQLRAMHHGHRIQVALAAEAHPAGVDTE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCH
ADLARVRRLIAEGEGAA
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDVVVVIPARYGASRLPGKPLLDLHGEPMIARVWQRACKSDATRVVIATDDERIEAAMQ
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHC
PYGADVMLTAPDHPSGTDRLAEVAARLELDADTIVVNVQGDEPLLPPALIDQVVRRLADD
CCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCC
TTASIATLAEPIGDVETLFNPNVVKVVRDLHGRALYFSRAPVPWDREHFATRPDCLATDA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCHHHHHH
WLRHIGLYAYRAGFLAAYVDWLPSPLEQLEQLEQLRAMHHGHRIQVALAAEAHPAGVDTE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCH
ADLARVRRLIAEGEGAA
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA