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The map label for this gene is glnS [H]

Identifier: 91789206

GI number: 91789206

Start: 3546131

End: 3547969

Strand: Direct

Name: glnS [H]

Synonym: Bpro_3350

Alternate gene names: 91789206

Gene position: 3546131-3547969 (Clockwise)

Preceding gene: 91789204

Following gene: 91789207

Centisome position: 68.19

GC content: 62.48

Gene sequence:

>1839_bases
ATGACCTCCCCCGCCCCCTCCAAAGCTGGCCCCAAGGGCACTGCTGCCGCAGCCCCCGCCGACAAAGAAAACCACAAGCC
CAGCAACTTTTTGCGCCAGATCATCGAAAAAGACCTGGCTGAAGGCACGTATGCCACCCGCCGCTGGGGCGGCAGCCCTG
GCGATGCCGCCCACCACGCCAGCGGCCAGCCCGACCCGGCCCGGGTGCGCCTGCGCTTTCCGCCCGAGCCCAACGGCTAC
CTGCACATCGGCCACGCCAAGAGCATTTACCTGAACTTTGGCCTGGCGCGCGACTACGGCGGCGTGTGCCACCTGCGCTT
TGACGACACCAACCCCGAAAAAGAAGACACCGAATACGTCAGCAGCATCATTGAAGCGGTGAAGTGGCTGGGTTTTGACT
GGGAAAACAACGGCCCATCCGGCAACGAGTGCAACCTCTATCAGGCCAGCGACTATTTCGACTTCATGTACCGCGCCGCC
GAATACCTGATCGAATCCGGCAACGCCTATGTAGACGAGCAAACCGCCGAGGAAATGCGCCTCAGCCGCGGCGACTTCGG
CCACCCCGGCACCAACAGCCCCTTTCGCAGCCGCACGCCAGAGCAAAACCTGGCGCGCTTTCGCGAAATGCGTGACGGCC
TGCATGAAGACGGCTCCATGGTGCTGCGCGCCAAGATCGACATGGCCAGCCCCAACATCAATATGCGCGACCCGGCCATT
TACCGCATTCGCCGCGCCCACCACCACAACACCGGCGACAAATGGTGCATCTACCCCATGTACACCTTTGCGCACCCCAT
CGAGGACGCACTGGAGCAGATCACCCACAGCATCTGCACGCTGGAGTTTGAAGACCAGCGCCCGTTTTACGACTGGCTGC
TCGACCGCCTGTGCGAAGGCGGCCTGGTTGCCACGCCGCACCCGCACCAGTACGAATTTGCCCGCCTCAACCTCACCTAT
GTGCTGACCAGCAAACGCAAGCTGGCGCAACTGGTGTACGACCACAAGGTCACCGGCTGGGACGACCCCCGCATGCCAAC
CATCGTCGGCCTGCGCCGCCGCGGCTACACCCCCGAAGCGCTGCACCTGTTCGCCGAACGCATTGGCGTGACCAAGAGCG
ACAGCTGGATTGACTACAGCACGCTGGAAGGCGCACTGCGCGACACACTGGACCCCATCGCCCCCCGCGCCATGGCCGTG
CTCGACCCCGTCAAGTTGGTGCTGACCAATTGGGACACGGTCATGGGCGCAGGCAAGCTCGACGACTGCAGCGCCCCCGT
GCACCCGCACCACCCCGAGCTGGGCAAGCGCAGTTTCAAAATCGGCAAAGAAGTGTGGATTGAACGCACCGACTTTGAAG
AGACACCCCCCAAAGGCTTCTTCCGCCTGTTCCCGGGCAACAAGGTGCGCCTCAAATACGGCCACGTCATCGAATGCACA
GGAGCTACCCGCGACGCCAACGGCCAGGTCACCGAAGTACAGGCCACGCTGATCCCCGACACCAAGAGCGGCACCCCCGG
CTCGGACGCCATCAAGGTCAAGGGCGTGATCACCTGGGTAGGCGTGAATGATGCGGTGCAGGCCGAAGTGCGCCTCTATG
ACCGCCTCTTCAAGGAAGCCCACCCCGGTACGGGCGAGAAGGACTTTATGGAAGAGCTGAATCCGGACAGCCTGAAGGTG
GTGACGGCGTATGTGGAGCCTTCATTGGCCAGCGCGCCTGCTGGCCAGCGCTTCCAGTTTGAGCGGCATGGGTACTTTGT
CACAGACATTGTTGACCACAAGCCGGGGAAAACCGTGTTCAATCGGGTGACGGGGATGAAAGATAGCTGGGGAAAGTAG

Upstream 100 bases:

>100_bases
TGTGTTTATTAAACGCTGGATACCGGTAACGGCTTACCGCATGCACAGTTAAGAGCGTAGCCAAACGTAACGTCTTGCCC
AACCGCCTAAAATCATTCGC

Downstream 100 bases:

>100_bases
CGTGATTGTCGATACGCAGTTGCCTACAAATGAACTTTTCCCTGTAACGAATCATGCACAACCCGTTTTACGCTGGGCCG
GCAGCAAGCGTCGCATCACC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 612; Mature: 611

Protein sequence:

>612_residues
MTSPAPSKAGPKGTAAAAPADKENHKPSNFLRQIIEKDLAEGTYATRRWGGSPGDAAHHASGQPDPARVRLRFPPEPNGY
LHIGHAKSIYLNFGLARDYGGVCHLRFDDTNPEKEDTEYVSSIIEAVKWLGFDWENNGPSGNECNLYQASDYFDFMYRAA
EYLIESGNAYVDEQTAEEMRLSRGDFGHPGTNSPFRSRTPEQNLARFREMRDGLHEDGSMVLRAKIDMASPNINMRDPAI
YRIRRAHHHNTGDKWCIYPMYTFAHPIEDALEQITHSICTLEFEDQRPFYDWLLDRLCEGGLVATPHPHQYEFARLNLTY
VLTSKRKLAQLVYDHKVTGWDDPRMPTIVGLRRRGYTPEALHLFAERIGVTKSDSWIDYSTLEGALRDTLDPIAPRAMAV
LDPVKLVLTNWDTVMGAGKLDDCSAPVHPHHPELGKRSFKIGKEVWIERTDFEETPPKGFFRLFPGNKVRLKYGHVIECT
GATRDANGQVTEVQATLIPDTKSGTPGSDAIKVKGVITWVGVNDAVQAEVRLYDRLFKEAHPGTGEKDFMEELNPDSLKV
VTAYVEPSLASAPAGQRFQFERHGYFVTDIVDHKPGKTVFNRVTGMKDSWGK

Sequences:

>Translated_612_residues
MTSPAPSKAGPKGTAAAAPADKENHKPSNFLRQIIEKDLAEGTYATRRWGGSPGDAAHHASGQPDPARVRLRFPPEPNGY
LHIGHAKSIYLNFGLARDYGGVCHLRFDDTNPEKEDTEYVSSIIEAVKWLGFDWENNGPSGNECNLYQASDYFDFMYRAA
EYLIESGNAYVDEQTAEEMRLSRGDFGHPGTNSPFRSRTPEQNLARFREMRDGLHEDGSMVLRAKIDMASPNINMRDPAI
YRIRRAHHHNTGDKWCIYPMYTFAHPIEDALEQITHSICTLEFEDQRPFYDWLLDRLCEGGLVATPHPHQYEFARLNLTY
VLTSKRKLAQLVYDHKVTGWDDPRMPTIVGLRRRGYTPEALHLFAERIGVTKSDSWIDYSTLEGALRDTLDPIAPRAMAV
LDPVKLVLTNWDTVMGAGKLDDCSAPVHPHHPELGKRSFKIGKEVWIERTDFEETPPKGFFRLFPGNKVRLKYGHVIECT
GATRDANGQVTEVQATLIPDTKSGTPGSDAIKVKGVITWVGVNDAVQAEVRLYDRLFKEAHPGTGEKDFMEELNPDSLKV
VTAYVEPSLASAPAGQRFQFERHGYFVTDIVDHKPGKTVFNRVTGMKDSWGK
>Mature_611_residues
TSPAPSKAGPKGTAAAAPADKENHKPSNFLRQIIEKDLAEGTYATRRWGGSPGDAAHHASGQPDPARVRLRFPPEPNGYL
HIGHAKSIYLNFGLARDYGGVCHLRFDDTNPEKEDTEYVSSIIEAVKWLGFDWENNGPSGNECNLYQASDYFDFMYRAAE
YLIESGNAYVDEQTAEEMRLSRGDFGHPGTNSPFRSRTPEQNLARFREMRDGLHEDGSMVLRAKIDMASPNINMRDPAIY
RIRRAHHHNTGDKWCIYPMYTFAHPIEDALEQITHSICTLEFEDQRPFYDWLLDRLCEGGLVATPHPHQYEFARLNLTYV
LTSKRKLAQLVYDHKVTGWDDPRMPTIVGLRRRGYTPEALHLFAERIGVTKSDSWIDYSTLEGALRDTLDPIAPRAMAVL
DPVKLVLTNWDTVMGAGKLDDCSAPVHPHHPELGKRSFKIGKEVWIERTDFEETPPKGFFRLFPGNKVRLKYGHVIECTG
ATRDANGQVTEVQATLIPDTKSGTPGSDAIKVKGVITWVGVNDAVQAEVRLYDRLFKEAHPGTGEKDFMEELNPDSLKVV
TAYVEPSLASAPAGQRFQFERHGYFVTDIVDHKPGKTVFNRVTGMKDSWGK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=553, Percent_Identity=42.1338155515371, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI62241042, Length=525, Percent_Identity=32.5714285714286, Blast_Score=254, Evalue=2e-67,
Organism=Escherichia coli, GI1786895, Length=587, Percent_Identity=51.9591141396934, Blast_Score=587, Evalue=1e-168,
Organism=Escherichia coli, GI1788743, Length=103, Percent_Identity=32.0388349514563, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17543332, Length=550, Percent_Identity=40.5454545454545, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17511007, Length=533, Percent_Identity=33.2082551594747, Blast_Score=255, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6324742, Length=585, Percent_Identity=39.6581196581197, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321192, Length=531, Percent_Identity=33.8983050847458, Blast_Score=262, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17864488, Length=550, Percent_Identity=39.2727272727273, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24649466, Length=528, Percent_Identity=34.469696969697, Blast_Score=273, Evalue=3e-73,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 68875; Mature: 68744

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPAPSKAGPKGTAAAAPADKENHKPSNFLRQIIEKDLAEGTYATRRWGGSPGDAAHHA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
SGQPDPARVRLRFPPEPNGYLHIGHAKSIYLNFGLARDYGGVCHLRFDDTNPEKEDTEYV
CCCCCCCEEEEECCCCCCCEEEECCCEEEEEEECEECCCCCEEEEEECCCCCCHHHHHHH
SSIIEAVKWLGFDWENNGPSGNECNLYQASDYFDFMYRAAEYLIESGNAYVDEQTAEEMR
HHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEECHHHHHHHH
LSRGDFGHPGTNSPFRSRTPEQNLARFREMRDGLHEDGSMVLRAKIDMASPNINMRDPAI
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCHH
YRIRRAHHHNTGDKWCIYPMYTFAHPIEDALEQITHSICTLEFEDQRPFYDWLLDRLCEG
HHHHHHHCCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCC
GLVATPHPHQYEFARLNLTYVLTSKRKLAQLVYDHKVTGWDDPRMPTIVGLRRRGYTPEA
CEEECCCCCCCEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHH
LHLFAERIGVTKSDSWIDYSTLEGALRDTLDPIAPRAMAVLDPVKLVLTNWDTVMGAGKL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHCCCCC
DDCSAPVHPHHPELGKRSFKIGKEVWIERTDFEETPPKGFFRLFPGNKVRLKYGHVIECT
CCCCCCCCCCCCCCCCHHHHCCHHHEEECCCCCCCCCCCEEEECCCCEEEEEECCEEEEC
GATRDANGQVTEVQATLIPDTKSGTPGSDAIKVKGVITWVGVNDAVQAEVRLYDRLFKEA
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHC
HPGTGEKDFMEELNPDSLKVVTAYVEPSLASAPAGQRFQFERHGYFVTDIVDHKPGKTVF
CCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCEEEEEECCCCCCHHHH
NRVTGMKDSWGK
HHHCCCCCCCCC
>Mature Secondary Structure 
TSPAPSKAGPKGTAAAAPADKENHKPSNFLRQIIEKDLAEGTYATRRWGGSPGDAAHHA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
SGQPDPARVRLRFPPEPNGYLHIGHAKSIYLNFGLARDYGGVCHLRFDDTNPEKEDTEYV
CCCCCCCEEEEECCCCCCCEEEECCCEEEEEEECEECCCCCEEEEEECCCCCCHHHHHHH
SSIIEAVKWLGFDWENNGPSGNECNLYQASDYFDFMYRAAEYLIESGNAYVDEQTAEEMR
HHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEECHHHHHHHH
LSRGDFGHPGTNSPFRSRTPEQNLARFREMRDGLHEDGSMVLRAKIDMASPNINMRDPAI
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCHH
YRIRRAHHHNTGDKWCIYPMYTFAHPIEDALEQITHSICTLEFEDQRPFYDWLLDRLCEG
HHHHHHHCCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCC
GLVATPHPHQYEFARLNLTYVLTSKRKLAQLVYDHKVTGWDDPRMPTIVGLRRRGYTPEA
CEEECCCCCCCEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHH
LHLFAERIGVTKSDSWIDYSTLEGALRDTLDPIAPRAMAVLDPVKLVLTNWDTVMGAGKL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHCCCCC
DDCSAPVHPHHPELGKRSFKIGKEVWIERTDFEETPPKGFFRLFPGNKVRLKYGHVIECT
CCCCCCCCCCCCCCCCHHHHCCHHHEEECCCCCCCCCCCEEEECCCCEEEEEECCEEEEC
GATRDANGQVTEVQATLIPDTKSGTPGSDAIKVKGVITWVGVNDAVQAEVRLYDRLFKEA
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHC
HPGTGEKDFMEELNPDSLKVVTAYVEPSLASAPAGQRFQFERHGYFVTDIVDHKPGKTVF
CCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCEEEEEECCCCCCHHHH
NRVTGMKDSWGK
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]