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The map label for this gene is pcaU [H]

Identifier: 91787725

GI number: 91787725

Start: 1907716

End: 1908507

Strand: Reverse

Name: pcaU [H]

Synonym: Bpro_1846

Alternate gene names: 91787725

Gene position: 1908507-1907716 (Counterclockwise)

Preceding gene: 91787738

Following gene: 91787724

Centisome position: 36.7

GC content: 64.9

Gene sequence:

>792_bases
ATGACAATGCCTGCCCCGCCAGCGCCCCCCTCGCCAGCACTCGACAAACGTGACTGGATTGCCGGGCTGGAAAAAGGCCT
TTCCATCATTGAATGTTTTGACGACGCGAATCCCCGCCTGACGGCCAGCCAGGCTGGCGCCCGCTGTGGCATGACACGTA
CCGCGGCACGCCGCTACCTGCTGACGCTGGAATACCTGGGTTACGTGGCCAGCGACGGAAAGCTGTTCTGGCTGACCCCA
CGCGTTTTGAGGCTCGGGCAGTCTTACCTTGAATCGGCCCGGCTGCCGCGCATCGTGCAGCCCTTCCTGCAGCGCGTGAC
CGCCGGCACGCAGGAAAGCGCCTATGTGAGCGTGATGGACGGCGACGAGGTCGTGTACATCGCGCGCAACGGCACCAACC
GCGCGATGAACACCGGCTACGTACTCGGCTCGCGCGTGCAGGCCCAGGTCACCGCCGCCGGCCTGCTGATGCTGTCCCTG
CGCGACCCCGGCTGGCTGGAAAACTGGTTCGCCACCCACGAACTCAAGGCCTATACCTCCTACACCATTGCCAGCAAGGA
CCGCCTGCGCATCGAGCTGGCGCGCGTGCGTGCCCAAGGGTGGGCCATTTCAGAGCAGCAGCTGGAACTCAATTACCGCG
GCATTGCCGTGCCGTTGCGTGACCGGCATGGTGATGTGGCCGGCGCCCTGAGCGTGACCATGCCCATGGGCCATGAATCA
AGCGAAGAGGCCGTCGCCCGTGTGCTGCAGGTACTGCGCGAAACGGCGCAGGCCATGCGCAACCTGATCTGA

Upstream 100 bases:

>100_bases
TCGAAATTGAACGATAATCGAACATTATTGATCGATCATCGATCAAAGCGAGGGTTTCACCTCATATTGATGGCCGAACC
ACTCCCACAATACTTGGCCC

Downstream 100 bases:

>100_bases
ATGCCGTCGGTACGTAATCTGAACATCATCTGAACGCCGACCGTGCATTCAGCAAAAGTTATTGCCGGTATTGCCGGTAT
TGCCGACCGCCAAAAATAGG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTMPAPPAPPSPALDKRDWIAGLEKGLSIIECFDDANPRLTASQAGARCGMTRTAARRYLLTLEYLGYVASDGKLFWLTP
RVLRLGQSYLESARLPRIVQPFLQRVTAGTQESAYVSVMDGDEVVYIARNGTNRAMNTGYVLGSRVQAQVTAAGLLMLSL
RDPGWLENWFATHELKAYTSYTIASKDRLRIELARVRAQGWAISEQQLELNYRGIAVPLRDRHGDVAGALSVTMPMGHES
SEEAVARVLQVLRETAQAMRNLI

Sequences:

>Translated_263_residues
MTMPAPPAPPSPALDKRDWIAGLEKGLSIIECFDDANPRLTASQAGARCGMTRTAARRYLLTLEYLGYVASDGKLFWLTP
RVLRLGQSYLESARLPRIVQPFLQRVTAGTQESAYVSVMDGDEVVYIARNGTNRAMNTGYVLGSRVQAQVTAAGLLMLSL
RDPGWLENWFATHELKAYTSYTIASKDRLRIELARVRAQGWAISEQQLELNYRGIAVPLRDRHGDVAGALSVTMPMGHES
SEEAVARVLQVLRETAQAMRNLI
>Mature_262_residues
TMPAPPAPPSPALDKRDWIAGLEKGLSIIECFDDANPRLTASQAGARCGMTRTAARRYLLTLEYLGYVASDGKLFWLTPR
VLRLGQSYLESARLPRIVQPFLQRVTAGTQESAYVSVMDGDEVVYIARNGTNRAMNTGYVLGSRVQAQVTAAGLLMLSLR
DPGWLENWFATHELKAYTSYTIASKDRLRIELARVRAQGWAISEQQLELNYRGIAVPLRDRHGDVAGALSVTMPMGHESS
EEAVARVLQVLRETAQAMRNLI

Specific function: Activates transcription of the pca operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=252, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789999, Length=244, Percent_Identity=26.6393442622951, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87082359, Length=235, Percent_Identity=23.4042553191489, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786468, Length=217, Percent_Identity=23.963133640553, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786715, Length=237, Percent_Identity=21.5189873417722, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29109; Mature: 28978

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMPAPPAPPSPALDKRDWIAGLEKGLSIIECFDDANPRLTASQAGARCGMTRTAARRYL
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHCCCCCCEEHHHCCCCCCCHHHHHHHHH
LTLEYLGYVASDGKLFWLTPRVLRLGQSYLESARLPRIVQPFLQRVTAGTQESAYVSVMD
HHHHHHHEEECCCEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEC
GDEVVYIARNGTNRAMNTGYVLGSRVQAQVTAAGLLMLSLRDPGWLENWFATHELKAYTS
CCEEEEEEECCCCCCCCCCEEECCCHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHHE
YTIASKDRLRIELARVRAQGWAISEQQLELNYRGIAVPLRDRHGDVAGALSVTMPMGHES
EEECCCCHHHHHHHHHHHCCCCCCHHHEEEEECEEEEEECCCCCCEEEEEEEEECCCCCC
SEEAVARVLQVLRETAQAMRNLI
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMPAPPAPPSPALDKRDWIAGLEKGLSIIECFDDANPRLTASQAGARCGMTRTAARRYL
CCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHCCCCCCEEHHHCCCCCCCHHHHHHHHH
LTLEYLGYVASDGKLFWLTPRVLRLGQSYLESARLPRIVQPFLQRVTAGTQESAYVSVMD
HHHHHHHEEECCCEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEC
GDEVVYIARNGTNRAMNTGYVLGSRVQAQVTAAGLLMLSLRDPGWLENWFATHELKAYTS
CCEEEEEEECCCCCCCCCCEEECCCHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHHE
YTIASKDRLRIELARVRAQGWAISEQQLELNYRGIAVPLRDRHGDVAGALSVTMPMGHES
EEECCCCHHHHHHHHHHHCCCCCCHHHEEEEECEEEEEECCCCCCEEEEEEEEECCCCCC
SEEAVARVLQVLRETAQAMRNLI
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515921 [H]