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The map label for this gene is infA2

Identifier: 91787251

GI number: 91787251

Start: 1395697

End: 1395954

Strand: Direct

Name: infA2

Synonym: Bpro_1356

Alternate gene names: 91787251

Gene position: 1395697-1395954 (Clockwise)

Preceding gene: 91787250

Following gene: 91787253

Centisome position: 26.84

GC content: 61.24

Gene sequence:

>258_bases
ATGGCCAAAGAAGAACTGATTGAAATGCATGGACTGGTAGACGAAGTGCTGCCCGATTCGCGTTTCCGCGTGACGCTCGA
CAATGGCCACAAACTGGTGGCCTATACCTCGGGCAAGATGCGCAAGAACCATATCCGCATCCTGGCCGGCGACCAGGTGT
CGCTGGAGTTGTCGCCTTACGACCTGAGCAAGGGCCGCATCACCTTCCGCCACATCGCTGGCCGCGGCCCGGGCCCTGCC
CAGCGGCCTTCGCGCTAA

Upstream 100 bases:

>100_bases
GGGTCAGCCGGGACGGCCAGGTAGACGTTAGATAACCAAACCAGCCAAAAGACAGACAGATAGTCAAACAGGTTTTTTTC
AAATCTCAAGGAGTTACATC

Downstream 100 bases:

>100_bases
GCCAGGCCTTCGCAACGGAGCGGGAGACCTGCGTTCAGGGACAAGCGTTGCCGCAGTGAGGGTAGATCCGATGGCGGCTT
CTTTCGTGCCCGCCATGTGA

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MAKEELIEMHGLVDEVLPDSRFRVTLDNGHKLVAYTSGKMRKNHIRILAGDQVSLELSPYDLSKGRITFRHIAGRGPGPA
QRPSR

Sequences:

>Translated_85_residues
MAKEELIEMHGLVDEVLPDSRFRVTLDNGHKLVAYTSGKMRKNHIRILAGDQVSLELSPYDLSKGRITFRHIAGRGPGPA
QRPSR
>Mature_84_residues
AKEELIEMHGLVDEVLPDSRFRVTLDNGHKLVAYTSGKMRKNHIRILAGDQVSLELSPYDLSKGRITFRHIAGRGPGPAQ
RPSR

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=67.1428571428571, Blast_Score=101, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF12_POLSJ (Q12DT7)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_548203.1
- ProteinModelPortal:   Q12DT7
- SMR:   Q12DT7
- STRING:   Q12DT7
- GeneID:   4011967
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1356
- NMPDR:   fig|296591.1.peg.1901
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   VQLDAGH
- PhylomeDB:   Q12DT7
- ProtClustDB:   PRK12442
- BioCyc:   PSP296591:BPRO_1356-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 9536; Mature: 9405

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEELIEMHGLVDEVLPDSRFRVTLDNGHKLVAYTSGKMRKNHIRILAGDQVSLELSPY
CCHHHHHHHHCCHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCEEEEEECCC
DLSKGRITFRHIAGRGPGPAQRPSR
CCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AKEELIEMHGLVDEVLPDSRFRVTLDNGHKLVAYTSGKMRKNHIRILAGDQVSLELSPY
CHHHHHHHHCCHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCEEEEEECCC
DLSKGRITFRHIAGRGPGPAQRPSR
CCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA