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The map label for this gene is nahR [H]

Identifier: 91786878

GI number: 91786878

Start: 996134

End: 997030

Strand: Direct

Name: nahR [H]

Synonym: Bpro_0978

Alternate gene names: 91786878

Gene position: 996134-997030 (Clockwise)

Preceding gene: 91786876

Following gene: 91786880

Centisome position: 19.16

GC content: 69.34

Gene sequence:

>897_bases
ATGGCGACACCCGATTTCAACTTGCTGGTCACCCTTGATGTGCTGCTCGCGGAAGGCAGCGTTGTGCGCGCGGCCCGGCG
CTTGCGGCTCAGCCCGTCGGCGATGAGCCGGGCGCTGGCGAGGTTGCGCGAGACGACGGGCGATCCGCTGCTGGTCAGGG
CCGGGCGCGGCCTCGTCCCCACACCCCGGGCGATAGCACTGCGCGAGCAGGTCGGCCAGCTCGTGCAGGACGCGGAAGCG
GTTCTGCGCCCCGTGGAGAAGCTCAAGCTCAAAAAGCTGGTCCGAACCTTCACGCTGCGGACCCGCGAAGGCTTTGTGGA
GAACTTCGGGCCGGCGCTCATTGCCCGCGTCGGCCAGGAGGCGCCCGGCGTGCGGCTGTGCTTCGTGCAGAAGCTGGACA
AAGACAGCACGCCGCTGCGCGACGGGACCGTCGACCTGGAAACCGGCGTGGTGGGCAGGGCGACGGCTCCTGAGCTGCGC
GTGCAGGCCTTGTTCCGGGACCGCTTCATTGGCGTCGTGCGAGCGGGGCACCCGCTGAGCCAGGGCGAGATCACGCCGGC
CCGTTATGCGGCCAGCAGGCACATCGGCGTCTCGCGGCGGGGTCTGGGCGCGGAGCCGGTGGATGAAGCCTTGGTGCCGC
TCGGGCTGCAAAGGGAAATCGCCACCATCGTCGGCGGTTTTTCGGCCGCGCTGGCGCTGGCCCGGGCCTCAGACCTGATC
GCCACTGTTCCCGAACGGCATACCGGAAACCTGCGCGCCGGTATGCACAGTTTTCCCCTTCCGGTCGCCACGCCGGAGAT
CACGGTGTCATTGCTCTGGCACCCACGGCTGGATGCCGATCCGGCGCATCGCTGGCTGCGCGGGTGTGTTCGGGACGCCT
GCGCGGACATCCGCTGA

Upstream 100 bases:

>100_bases
GAAGCGTAGTTCTTTGCCTGGCATAGCGGAAGGCGCACCATTTGCACTTTATTCGTGCGTTTAACGCCATGTCACGGCCA
AACTGCGCTATGGTCGATGC

Downstream 100 bases:

>100_bases
ATGGAAAAGTATGCCGGAGTCAGAGTGTCATAGCGTAGACGTGGTGCTCATCATCGTCGGGCGTGGCCCGCCACAGACAG
GTTCACAGACAGGTTTAAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MATPDFNLLVTLDVLLAEGSVVRAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRAIALREQVGQLVQDAEA
VLRPVEKLKLKKLVRTFTLRTREGFVENFGPALIARVGQEAPGVRLCFVQKLDKDSTPLRDGTVDLETGVVGRATAPELR
VQALFRDRFIGVVRAGHPLSQGEITPARYAASRHIGVSRRGLGAEPVDEALVPLGLQREIATIVGGFSAALALARASDLI
ATVPERHTGNLRAGMHSFPLPVATPEITVSLLWHPRLDADPAHRWLRGCVRDACADIR

Sequences:

>Translated_298_residues
MATPDFNLLVTLDVLLAEGSVVRAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRAIALREQVGQLVQDAEA
VLRPVEKLKLKKLVRTFTLRTREGFVENFGPALIARVGQEAPGVRLCFVQKLDKDSTPLRDGTVDLETGVVGRATAPELR
VQALFRDRFIGVVRAGHPLSQGEITPARYAASRHIGVSRRGLGAEPVDEALVPLGLQREIATIVGGFSAALALARASDLI
ATVPERHTGNLRAGMHSFPLPVATPEITVSLLWHPRLDADPAHRWLRGCVRDACADIR
>Mature_297_residues
ATPDFNLLVTLDVLLAEGSVVRAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRAIALREQVGQLVQDAEAV
LRPVEKLKLKKLVRTFTLRTREGFVENFGPALIARVGQEAPGVRLCFVQKLDKDSTPLRDGTVDLETGVVGRATAPELRV
QALFRDRFIGVVRAGHPLSQGEITPARYAASRHIGVSRRGLGAEPVDEALVPLGLQREIATIVGGFSAALALARASDLIA
TVPERHTGNLRAGMHSFPLPVATPEITVSLLWHPRLDADPAHRWLRGCVRDACADIR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=307, Percent_Identity=27.0358306188925, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=26.4214046822742, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786820, Length=111, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081766, Length=299, Percent_Identity=23.4113712374582, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32295; Mature: 32164

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPDFNLLVTLDVLLAEGSVVRAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCCCHHEEHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRAIALREQVGQLVQDAEAVLRPVEKLKLKKLVRTFTLRTREGFVENFGPALIARVGQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
APGVRLCFVQKLDKDSTPLRDGTVDLETGVVGRATAPELRVQALFRDRFIGVVRAGHPLS
CCCEEEEEEHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
QGEITPARYAASRHIGVSRRGLGAEPVDEALVPLGLQREIATIVGGFSAALALARASDLI
CCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATVPERHTGNLRAGMHSFPLPVATPEITVSLLWHPRLDADPAHRWLRGCVRDACADIR
HHCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATPDFNLLVTLDVLLAEGSVVRAARRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCCHHEEHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRAIALREQVGQLVQDAEAVLRPVEKLKLKKLVRTFTLRTREGFVENFGPALIARVGQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
APGVRLCFVQKLDKDSTPLRDGTVDLETGVVGRATAPELRVQALFRDRFIGVVRAGHPLS
CCCEEEEEEHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
QGEITPARYAASRHIGVSRRGLGAEPVDEALVPLGLQREIATIVGGFSAALALARASDLI
CCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATVPERHTGNLRAGMHSFPLPVATPEITVSLLWHPRLDADPAHRWLRGCVRDACADIR
HHCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]