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The map label for this gene is rppH [H]

Identifier: 91786736

GI number: 91786736

Start: 857531

End: 858250

Strand: Direct

Name: rppH [H]

Synonym: Bpro_0834

Alternate gene names: 91786736

Gene position: 857531-858250 (Clockwise)

Preceding gene: 91786733

Following gene: 91786737

Centisome position: 16.49

GC content: 60.56

Gene sequence:

>720_bases
ATGCTTGACCGGGATGGCTTTAGGCCTAACGTCGGCATCATCTTGCTCAACCAGAGAAGTCAGGTATTTTGGGGCAAACG
TATCCGTACCCACTCGTGGCAGTTTCCGCAGGGTGGCATTGATCGGGGCGAAAATCCCGAACAGGCCATGTACCGCGAAT
TGCATGAGGAAGTGGGGCTGTTGCCACAGCATGTTCATGTGCTGGCCCGTACCCGAGATTGGTTGCGCTATGAGGTGCCT
GACCGGTTTATCCGCCGCGATGCGCGCGGACATTACAAAGGCCAGAAGCAGATATGGTTCCTGCTGCAGCTGGTCGGTTA
CGACTGGAACCTGAACCTGCGCGCGACAGATCATCCCGAGTTTGACGCCTGGCGCTGGAACGACTACTGGGTGCCGCTCG
ACGTCGTGGTGGAGTTCAAGCGCGGCGTATACGAGATGGCGCTGACCGAACTGGCGCGCTTTGTGCCTCGGGTCGATCCA
CGCTCCGCTCCACGGCCTGATTCCCGGCCCGACCATCGCAACCGCTACCTGCGCGGCGGCGTGCATCTGCGTGATCAAAT
GGCGGGCCAAGCCGGCGAAGCCAATCCCCATCCGGCCAACAGCATGACATACAGCTACACGGCCAGATTGGGCGCCTCGT
TTGAATTGCCCCCTGGCGCCACCTTTGAACCCGATCCGCAGACCAGCCTGGGCGCGGATCCTTCGCCCCCCAAAACATGA

Upstream 100 bases:

>100_bases
GAATTCTGCGTTGGAAGGGGGCTGGAGCCCGGCCGTGCGCTTGGCGCTGGCGCCTTCGCTGTGCATAATGGACTCAGTTT
AAAAAATTTGAGGTTTGATT

Downstream 100 bases:

>100_bases
CTTTCAAACCGGCCGCTGCGGCCCGCCTTTCTTGTGTAGCGCTTGCGCTGGCTTTCAGTTGCGCGGTCTCGGCCCAGAGC
GCCACGGATGACCCGGACTG

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLDRDGFRPNVGIILLNQRSQVFWGKRIRTHSWQFPQGGIDRGENPEQAMYRELHEEVGLLPQHVHVLARTRDWLRYEVP
DRFIRRDARGHYKGQKQIWFLLQLVGYDWNLNLRATDHPEFDAWRWNDYWVPLDVVVEFKRGVYEMALTELARFVPRVDP
RSAPRPDSRPDHRNRYLRGGVHLRDQMAGQAGEANPHPANSMTYSYTARLGASFELPPGATFEPDPQTSLGADPSPPKT

Sequences:

>Translated_239_residues
MLDRDGFRPNVGIILLNQRSQVFWGKRIRTHSWQFPQGGIDRGENPEQAMYRELHEEVGLLPQHVHVLARTRDWLRYEVP
DRFIRRDARGHYKGQKQIWFLLQLVGYDWNLNLRATDHPEFDAWRWNDYWVPLDVVVEFKRGVYEMALTELARFVPRVDP
RSAPRPDSRPDHRNRYLRGGVHLRDQMAGQAGEANPHPANSMTYSYTARLGASFELPPGATFEPDPQTSLGADPSPPKT
>Mature_239_residues
MLDRDGFRPNVGIILLNQRSQVFWGKRIRTHSWQFPQGGIDRGENPEQAMYRELHEEVGLLPQHVHVLARTRDWLRYEVP
DRFIRRDARGHYKGQKQIWFLLQLVGYDWNLNLRATDHPEFDAWRWNDYWVPLDVVVEFKRGVYEMALTELARFVPRVDP
RSAPRPDSRPDHRNRYLRGGVHLRDQMAGQAGEANPHPANSMTYSYTARLGASFELPPGATFEPDPQTSLGADPSPPKT

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=175, Percent_Identity=50.8571428571429, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 27836; Mature: 27836

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRDGFRPNVGIILLNQRSQVFWGKRIRTHSWQFPQGGIDRGENPEQAMYRELHEEVGL
CCCCCCCCCCCCEEEECCCCCCHHCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPQHVHVLARTRDWLRYEVPDRFIRRDARGHYKGQKQIWFLLQLVGYDWNLNLRATDHPE
CHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCC
FDAWRWNDYWVPLDVVVEFKRGVYEMALTELARFVPRVDPRSAPRPDSRPDHRNRYLRGG
CCCEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCC
VHLRDQMAGQAGEANPHPANSMTYSYTARLGASFELPPGATFEPDPQTSLGADPSPPKT
CEEHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLDRDGFRPNVGIILLNQRSQVFWGKRIRTHSWQFPQGGIDRGENPEQAMYRELHEEVGL
CCCCCCCCCCCCEEEECCCCCCHHCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPQHVHVLARTRDWLRYEVPDRFIRRDARGHYKGQKQIWFLLQLVGYDWNLNLRATDHPE
CHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCC
FDAWRWNDYWVPLDVVVEFKRGVYEMALTELARFVPRVDPRSAPRPDSRPDHRNRYLRGG
CCCEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCC
VHLRDQMAGQAGEANPHPANSMTYSYTARLGASFELPPGATFEPDPQTSLGADPSPPKT
CEEHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA