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The map label for this gene is umuD [H]

Identifier: 89885828

GI number: 89885828

Start: 106393

End: 106833

Strand: Reverse

Name: umuD [H]

Synonym: Rfer_4342

Alternate gene names: 89885828

Gene position: 106833-106393 (Counterclockwise)

Preceding gene: 89885834

Following gene: 89885827

Centisome position: 41.5

GC content: 56.92

Gene sequence:

>441_bases
ATGATCAGTACACTCTCGCCGCAAAAACCGGTGCTCATTTCCGACGCTCCGCTGGTGGCGTTGCTGCTTAAAAACCGGGT
CTGCGCCGGCTTCCCGTCACCAGCAGAAGACCTTGGCGCGCAGCGTATTGACCTCACTCAGTTGCTTGTGACGCATCCTC
AGGCGACATACTTTCTTCGTGCAAGCGGGCAATCCATGATCGAAGCCGGGATTTTTGACGGTGACATCCTGGTGGTCGAC
CGTGCCATCAAGCCGCGACACGGACACATCGTTATCGCGATTCTGGACGGTGATTTCACGGTCAAGCAGCTCCATCAGCG
CCAGGGCCGCATCAAGCTCAAGGCCGCCAATCCGACGTTCGCGGAGATCGTGCCGAAGGACGGCCAGACCATTGAAATCT
GGGGTGTTGTTACCGCCACCATCAAGCAATTATTGAGCTGA

Upstream 100 bases:

>100_bases
GTGTTCATGGTCTCACTCCAAGTCTCAGTATTTATCGTACCTTGATGACTCGGCAATTGCCAGTCATTGCTGTCTGCCAA
CCGCGACATATACTGTATGG

Downstream 100 bases:

>100_bases
TTTTTCGTGTACGCCCTCGTTGATTGCAATAATTTTTATGCCAGCTGTGAACGCGTGTTTCGCCCCAGTTTGCGGGGCAT
ACCTGTGGTCGTGCTCAGCA

Product: putative prophage repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MISTLSPQKPVLISDAPLVALLLKNRVCAGFPSPAEDLGAQRIDLTQLLVTHPQATYFLRASGQSMIEAGIFDGDILVVD
RAIKPRHGHIVIAILDGDFTVKQLHQRQGRIKLKAANPTFAEIVPKDGQTIEIWGVVTATIKQLLS

Sequences:

>Translated_146_residues
MISTLSPQKPVLISDAPLVALLLKNRVCAGFPSPAEDLGAQRIDLTQLLVTHPQATYFLRASGQSMIEAGIFDGDILVVD
RAIKPRHGHIVIAILDGDFTVKQLHQRQGRIKLKAANPTFAEIVPKDGQTIEIWGVVTATIKQLLS
>Mature_146_residues
MISTLSPQKPVLISDAPLVALLLKNRVCAGFPSPAEDLGAQRIDLTQLLVTHPQATYFLRASGQSMIEAGIFDGDILVVD
RAIKPRHGHIVIAILDGDFTVKQLHQRQGRIKLKAANPTFAEIVPKDGQTIEIWGVVTATIKQLLS

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=123, Percent_Identity=49.5934959349593, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1790476, Length=127, Percent_Identity=33.8582677165354, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 15869; Mature: 15869

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTLSPQKPVLISDAPLVALLLKNRVCAGFPSPAEDLGAQRIDLTQLLVTHPQATYFLR
CCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCEEEEEE
ASGQSMIEAGIFDGDILVVDRAIKPRHGHIVIAILDGDFTVKQLHQRQGRIKLKAANPTF
ECCCCHHECCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHCCCEEEEECCCCC
AEIVPKDGQTIEIWGVVTATIKQLLS
EEEECCCCCEEEEEEEHHHHHHHHHC
>Mature Secondary Structure
MISTLSPQKPVLISDAPLVALLLKNRVCAGFPSPAEDLGAQRIDLTQLLVTHPQATYFLR
CCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCEEEEEE
ASGQSMIEAGIFDGDILVVDRAIKPRHGHIVIAILDGDFTVKQLHQRQGRIKLKAANPTF
ECCCCHHECCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHCCCEEEEECCCCC
AEIVPKDGQTIEIWGVVTATIKQLLS
EEEECCCCCEEEEEEEHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]