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The map label for this gene is ruvB [H]

Identifier: 89256412

GI number: 89256412

Start: 1029467

End: 1030513

Strand: Direct

Name: ruvB [H]

Synonym: FTL_1077

Alternate gene names: 89256412

Gene position: 1029467-1030513 (Clockwise)

Preceding gene: 89256411

Following gene: 89256415

Centisome position: 54.3

GC content: 37.06

Gene sequence:

>1047_bases
ATGATCGAAACAGATAGAATAATCTCAGCTAATACAGCTCAAACCAATGATGAAAATGTTATAGATAGAGCTATTAGACC
AAAAACTTTGGCAGAGTATGAGGGTCAACCAGCTGTACGCGAACAGATGGAGATTTTTATTCAAGCAGCAAAAGCACGTA
AAGATGCTCTTGATCATACACTTATATTTGGACCTCCTGGCTTAGGCAAAACAACCTTATCAAATATTATTGCCAATGAG
ATGGGGGTTGAGCTTAAGCAGACAAGTGGTCCAGTTCTAGAAAAAGCTGGTGATTTAGCTGCACTTTTGACTAATCTTGA
AGAGAATGATGTGTTATTTATTGATGAAATTCATCGCTTAAGTCCAGTTGTAGAAGAAATTCTCTATCCTGCTATGGAGG
ACTACCAACTTGATATAATGATAGGTGAAGGTCCAGCAGCGAGATCTATAAAAATTGATTTACCGCCGTTTACATTAGTT
GGAGCAACTACAAGAGCAGGGCTTTTGACATCACCTTTGCGTGATAGATTTGGTATTATCCAGCGACTAGAGTTTTATTC
GATAGATGATTTGTCAAAAATTGTTTATCGTTCAGCAAAGTTATTAAATCTAGATATTACTACTGATGGCGCAATGGAGA
TTGCAAAACGCTCAAGGGGAACACCTAGAATTGCTAATAGACTTTTACGTAGAGTAAGAGACTACGCTCAAGTTAAAGGT
TCTGGAGTAATCTGCTTTGAAATTGCTGATAAAGCTTTGAGTATGCTTAAAGTCGATCCTGTTGGTTTTGATCATATGGA
TCATAGGTATTTGCTTACATTAATGGAAAAATTTGCTGGTGGACCGGTGGGACTAGATACAATGTCGGCAGCTTTAAGTG
AAGAAAAGGGTACCATTGAGGATGTTATTGAACCTTATTTAATTCAACAGGGCTATATTATGCGTACAGCTAGAGGACGT
ATTGCGACTCTATTAGCATATAACCATTTCAAATTAAAAATCCCAGATAACTTAAGTGCAGATCAACAACAAACTCTATC
AATATAA

Upstream 100 bases:

>100_bases
CTTAATTCCTATAGATGGTGGCTATACAGCGCAATAGTATTGTCAACATATAAGATAAAAATGTTATAATTATTAGCAAA
TTTTATTATAAAACTACAGT

Downstream 100 bases:

>100_bases
GAATTCTAAAAGATTTAGCTATTAGTTAGATAACCTTAGGCTTAGCAAGAACTAGAGAATTTATCAAGATTGTTATATTT
AATCACATCTTTTATTCTAT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHTLIFGPPGLGKTTLSNIIANE
MGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLV
GATTRAGLLTSPLRDRFGIIQRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKG
SGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIEDVIEPYLIQQGYIMRTARGR
IATLLAYNHFKLKIPDNLSADQQQTLSI

Sequences:

>Translated_348_residues
MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHTLIFGPPGLGKTTLSNIIANE
MGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLV
GATTRAGLLTSPLRDRFGIIQRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKG
SGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIEDVIEPYLIQQGYIMRTARGR
IATLLAYNHFKLKIPDNLSADQQQTLSI
>Mature_348_residues
MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHTLIFGPPGLGKTTLSNIIANE
MGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLV
GATTRAGLLTSPLRDRFGIIQRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKG
SGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIEDVIEPYLIQQGYIMRTARGR
IATLLAYNHFKLKIPDNLSADQQQTLSI

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=336, Percent_Identity=72.6190476190476, Blast_Score=500, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38627; Mature: 38627

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHT
CCCCCCEEECCCCCCCCHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCE
LIFGPPGLGKTTLSNIIANEMGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
SPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGLLTSPLRDRFGII
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCHHHHHHHHHHHHH
QRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKG
HHHHHCCHHHHHHHHHHCHHEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
SGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIE
CCEEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
DVIEPYLIQQGYIMRTARGRIATLLAYNHFKLKIPDNLSADQQQTLSI
HHHHHHHHCCCCEEEECCCCEEEEEEECEEEEECCCCCCCCCHHHCCC
>Mature Secondary Structure
MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHT
CCCCCCEEECCCCCCCCHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCE
LIFGPPGLGKTTLSNIIANEMGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
SPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGLLTSPLRDRFGII
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCHHHHHHHHHHHHH
QRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKG
HHHHHCCHHHHHHHHHHCHHEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
SGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIE
CCEEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
DVIEPYLIQQGYIMRTARGRIATLLAYNHFKLKIPDNLSADQQQTLSI
HHHHHHHHCCCCEEEECCCCEEEEEEECEEEEECCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA