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The map label for this gene is mip [H]

Identifier: 89256380

GI number: 89256380

Start: 998633

End: 999445

Strand: Reverse

Name: mip [H]

Synonym: FTL_1042

Alternate gene names: 89256380

Gene position: 999445-998633 (Counterclockwise)

Preceding gene: 89256381

Following gene: 89256361

Centisome position: 52.71

GC content: 34.32

Gene sequence:

>813_bases
ATGAAGTTAAAGAAAATAGTAGCAGTTATATCATGCTCATTATTAGGACTAGCTATGAGTTCATGTTCAACAAATACAGA
TTCCGTAGATTCTACGAATGCTCAACAAGTAACTAAAAATACTGAAGCTAAAGGTGTTGCTACAAACAAATCAGCTCAAG
ATAATCCAACAATAAAAATGGGAGCTAATGCAAGCTACGTAGTAGGCTATCAAGTAGGTGCTGGTATATCTAAGCAAGAT
TTTGGCTTATACGATAAGCAAACAATAGCCGGTTTTGCAGATGCTATCAATGGTAATAAGCCAAGAATCTCTGAGAGTCA
AATCCGCAGAAATATGGAAACTCTTAAAGATAAGATGATTAAAAAGCAACTAGATACAGCTAATTTAAATAAAACAAAAT
CACAAGAATTTATGGCACAAATTGCTAAAATGGATAATGCTATAAAAGTTGATGATGGTGTTTACTATCAAATGATTAAG
CAAGGCGATGGCAAAAAGCCTAAATCTGATAGTCAAGTTACAATAGCTTATAAAGGAACTACGCCAGTTATAGCTTACGA
AGATGATAAATCGAAACTAAACGAGGTCAAAGAAGCTAAACTAATTGGTCCTACATTTGACTCAAGTGATAGCGCAACAT
TCCCACTCAGAAACCTAATCGAATGTTGGAAAGATGCTATTCCTCAAATACCTAATGGATCAACAATAATATTATATTGC
TCTCCAGATAAGGCATATGGAACTAGAGCGCCCGCTGTCATAGGACCTAATCAAGCACTTTCTTTTGAAATTACGCTTAA
AGATTTTAAATAA

Upstream 100 bases:

>100_bases
GCTCTATCAAATATTTCTCCATCACAGATGTTAGATAAAGAGCTTTTTGATTTTATAAATATCTCAAAAGATGATATACA
AAGATAGTTAAGGAGAAAAA

Downstream 100 bases:

>100_bases
AAAATTTTTTATAAAAATTAATTCTTCCTATTTACTGCTAGATCACATAATAAAATCATAGCTTGCTTATATTCTGAATC
TGGTAAAAAATCTATTTGTT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase family protein

Products: NA

Alternate protein names: PPIase; Macrophage infectivity potentiator; Rotamase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKLKKIVAVISCSLLGLAMSSCSTNTDSVDSTNAQQVTKNTEAKGVATNKSAQDNPTIKMGANASYVVGYQVGAGISKQD
FGLYDKQTIAGFADAINGNKPRISESQIRRNMETLKDKMIKKQLDTANLNKTKSQEFMAQIAKMDNAIKVDDGVYYQMIK
QGDGKKPKSDSQVTIAYKGTTPVIAYEDDKSKLNEVKEAKLIGPTFDSSDSATFPLRNLIECWKDAIPQIPNGSTIILYC
SPDKAYGTRAPAVIGPNQALSFEITLKDFK

Sequences:

>Translated_270_residues
MKLKKIVAVISCSLLGLAMSSCSTNTDSVDSTNAQQVTKNTEAKGVATNKSAQDNPTIKMGANASYVVGYQVGAGISKQD
FGLYDKQTIAGFADAINGNKPRISESQIRRNMETLKDKMIKKQLDTANLNKTKSQEFMAQIAKMDNAIKVDDGVYYQMIK
QGDGKKPKSDSQVTIAYKGTTPVIAYEDDKSKLNEVKEAKLIGPTFDSSDSATFPLRNLIECWKDAIPQIPNGSTIILYC
SPDKAYGTRAPAVIGPNQALSFEITLKDFK
>Mature_270_residues
MKLKKIVAVISCSLLGLAMSSCSTNTDSVDSTNAQQVTKNTEAKGVATNKSAQDNPTIKMGANASYVVGYQVGAGISKQD
FGLYDKQTIAGFADAINGNKPRISESQIRRNMETLKDKMIKKQLDTANLNKTKSQEFMAQIAKMDNAIKVDDGVYYQMIK
QGDGKKPKSDSQVTIAYKGTTPVIAYEDDKSKLNEVKEAKLIGPTFDSSDSATFPLRNLIECWKDAIPQIPNGSTIILYC
SPDKAYGTRAPAVIGPNQALSFEITLKDFK

Specific function: May be an essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI87082390, Length=215, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789745, Length=193, Percent_Identity=27.4611398963731, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008104
- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29358; Mature: 29358

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKKIVAVISCSLLGLAMSSCSTNTDSVDSTNAQQVTKNTEAKGVATNKSAQDNPTIKM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEECCCCCCCCCCEEE
GANASYVVGYQVGAGISKQDFGLYDKQTIAGFADAINGNKPRISESQIRRNMETLKDKMI
CCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
KKQLDTANLNKTKSQEFMAQIAKMDNAIKVDDGVYYQMIKQGDGKKPKSDSQVTIAYKGT
HHHHCCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCC
TPVIAYEDDKSKLNEVKEAKLIGPTFDSSDSATFPLRNLIECWKDAIPQIPNGSTIILYC
CCEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
SPDKAYGTRAPAVIGPNQALSFEITLKDFK
CCCCCCCCCCCEEECCCCEEEEEEEEECCC
>Mature Secondary Structure
MKLKKIVAVISCSLLGLAMSSCSTNTDSVDSTNAQQVTKNTEAKGVATNKSAQDNPTIKM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEECCCCCCCCCCEEE
GANASYVVGYQVGAGISKQDFGLYDKQTIAGFADAINGNKPRISESQIRRNMETLKDKMI
CCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
KKQLDTANLNKTKSQEFMAQIAKMDNAIKVDDGVYYQMIKQGDGKKPKSDSQVTIAYKGT
HHHHCCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCC
TPVIAYEDDKSKLNEVKEAKLIGPTFDSSDSATFPLRNLIECWKDAIPQIPNGSTIILYC
CCEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
SPDKAYGTRAPAVIGPNQALSFEITLKDFK
CCCCCCCCCCCEEECCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535514; 12704232 [H]