Click here to switch to the map view.

The map label for this gene is hflK [H]

Identifier: 89256260

GI number: 89256260

Start: 879997

End: 881064

Strand: Direct

Name: hflK [H]

Synonym: FTL_0903

Alternate gene names: 89256260

Gene position: 879997-881064 (Clockwise)

Preceding gene: 89256256

Following gene: 89256261

Centisome position: 46.41

GC content: 33.71

Gene sequence:

>1068_bases
ATGATTAAAAAACTAAAACAAAAATGGTTTTGGAGTAAAAATTCGGAGCAGGGACCACCGGATTTAGAAGAAATGATTAA
AAGATTCTTTGGCAAAAAGAATAAAACTGATAATGATGATAATGAGAGTATATATTCAAAAAATGCTAACAAAAAACAAT
CAACATTCAATAAGCCACCGATTGCTAAAATAGTTACAATAATAGTAGCTTTGCTTATAGTTGCATGGGTTGGTTTTGGT
TTTTATGTTGTGCAGCCAGCTGAGCAAGCTATAGTACTTAGATTAGGTAAGTTTTCTAAATTAGTGGAGCCTGGTCTACA
TTGGCATCCCTTGGGTATTGATAAGGTTTATAAAGAAAATGTCCAAGAGTTGAAAACCATTTCTCTAAAGCGTGATATGC
TGACATCTGAGGAGAATATTGTGCATATTTCTTTCACAGTTCAATATCGTATTGCTGATTTAGAAAAATACTTATTTGCT
AATACAAATCCTACTTTGTTATTACAACAAGCTTTAGAAAGTGCAGTTAGACAAGTAGTTGGTGAGAATAAACTAGAGCA
AATATTAACAACTAATCGTGCCGTAATTACTCAGCAGGTTAGAAAAGAAATGGAAGCATTACTAGAAAAATATAATTCAG
GTATTTATGTTAGTGAGGTGATAATGCAACCAGCCCAAGCTCCAGATGCAGTTAAGAGTGCTTTTGATGATGTCATTAAA
GCGCGTGAAGATCGTGAGAGAGAGCAAAACGAAGCTGAAGCATACGCAAATAGAGTAGTACCAGTAGCACAAGGTAACGC
TCAAAGAATATTGGATCAAGCTAATGCTTATAAGCAAAAAATTGTTCTAGAAGCTCAAGGGGAAGTTGCTCAATTTGAAC
AACTGTTACCGATATATAAACAGTCTCCGGATATTGTGATGAATCAAATGTACTTTAATACTATCTCAAATGTGCTACAG
CATAATAAGATATTCTTGATAGATAGTGATGGTGCTAAGAATATTTTCTACGGTTTAAGTGATACACAAAAACAAGCACT
ATTATCAAATACGCAAGGAGGAAATTAA

Upstream 100 bases:

>100_bases
TAATTATTTACCAATAGTCCAAAAAATATAGAATTTTTTATATATAATAGTTAATGCTTGAGTTAAAATACTTTAATAAA
GTCTATAGGAATGATAATTT

Downstream 100 bases:

>100_bases
GATGAGTAAATTCCTAAAAATATTCTTATTGCTTGTAGTAGTCTTAGCTATAGTAGTATTAAGCACAAAATTTATTGTCA
AACAAGGCTCAGAAGCAGTT

Product: SPFH domain-containing protein/band 7 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPPIAKIVTIIVALLIVAWVGFG
FYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKENVQELKTISLKRDMLTSEENIVHISFTVQYRIADLEKYLFA
NTNPTLLLQQALESAVRQVVGENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYKQSPDIVMNQMYFNTISNVLQ
HNKIFLIDSDGAKNIFYGLSDTQKQALLSNTQGGN

Sequences:

>Translated_355_residues
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPPIAKIVTIIVALLIVAWVGFG
FYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKENVQELKTISLKRDMLTSEENIVHISFTVQYRIADLEKYLFA
NTNPTLLLQQALESAVRQVVGENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYKQSPDIVMNQMYFNTISNVLQ
HNKIFLIDSDGAKNIFYGLSDTQKQALLSNTQGGN
>Mature_355_residues
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPPIAKIVTIIVALLIVAWVGFG
FYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKENVQELKTISLKRDMLTSEENIVHISFTVQYRIADLEKYLFA
NTNPTLLLQQALESAVRQVVGENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYKQSPDIVMNQMYFNTISNVLQ
HNKIFLIDSDGAKNIFYGLSDTQKQALLSNTQGGN

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=253, Percent_Identity=45.4545454545455, Blast_Score=235, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 40422; Mature: 40422

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPP
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCC
IAKIVTIIVALLIVAWVGFGFYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKEN
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VQELKTISLKRDMLTSEENIVHISFTVQYRIADLEKYLFANTNPTLLLQQALESAVRQVV
HHHHHHHHHHHHHHCCCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYK
HHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
QSPDIVMNQMYFNTISNVLQHNKIFLIDSDGAKNIFYGLSDTQKQALLSNTQGGN
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIKKLKQKWFWSKNSEQGPPDLEEMIKRFFGKKNKTDNDDNESIYSKNANKKQSTFNKPP
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCC
IAKIVTIIVALLIVAWVGFGFYVVQPAEQAIVLRLGKFSKLVEPGLHWHPLGIDKVYKEN
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VQELKTISLKRDMLTSEENIVHISFTVQYRIADLEKYLFANTNPTLLLQQALESAVRQVV
HHHHHHHHHHHHHHCCCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GENKLEQILTTNRAVITQQVRKEMEALLEKYNSGIYVSEVIMQPAQAPDAVKSAFDDVIK
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
AREDREREQNEAEAYANRVVPVAQGNAQRILDQANAYKQKIVLEAQGEVAQFEQLLPIYK
HHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
QSPDIVMNQMYFNTISNVLQHNKIFLIDSDGAKNIFYGLSDTQKQALLSNTQGGN
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]