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The map label for this gene is hflX [H]

Identifier: 89256256

GI number: 89256256

Start: 877317

End: 878624

Strand: Direct

Name: hflX [H]

Synonym: FTL_0899

Alternate gene names: 89256256

Gene position: 877317-878624 (Clockwise)

Preceding gene: 89256255

Following gene: 89256260

Centisome position: 46.27

GC content: 33.64

Gene sequence:

>1308_bases
ATGGAATTTTTCCAATCGTATCAAGCAGGTAGTAAGTGCCTGCTTGTAAATATAAATTTCAAATATCATCGTGAACTTAA
TCCTGATTTAACAGAGTTGGAAGGCTTAGTTATAGCAGCAGAAAAAGTTGTATTGCAAGGTTTAGATTTTAACCATCCTG
AGCCAGATATCAAATACTTTTGCGGTATGGGTAAAATCGAAATGATTAAAAATAAACGCGATGAACTAGAAGCAGATTTA
GTTGTTTTTAACCACCCTTTAACTCCCTCTCAAGAACGTAATATTGAGAAATTTCTTGAGTGCAGAGTTATGGATAGAAC
TAGATTAATTCTAGAGATATTTTCATTACGTGCTAAAACTTATGAGGGTAAACTTCAGGTTGAGTTAGCACAGCTTAACT
ATCAATCAACACGTTTAGTCAAAGGATGGACTCACTTAGAGCGACAAAAGGGTGGTATTGGTGTACGTGGTGGACCTGGT
GAGACACAGCTTGAGATAGACAGACGTTTAATTAGACAGAGGATTAAGCAGATTGCACAAAAGCTTGAGAAAGTAAAACA
TCATCGTGATTTAAGTAGATCTTCGCGTAAAAAAAATAACATTCCAACTATTTCATTTGTGGGATATACGAATGCAGGTA
AATCAACTTTATTTAATAAAATCACAAATGCTGATGTTTTAGCTAAAGATCAGTTGTTTGCGACTTTAGATCCTACTTTG
CGTAAAGTAATCGTACCTAAACTCGGTGAGATTATATTCTCAGATACTGTAGGCTTTATCAAAAATTTACCACATAATTT
AGTTGAAGCTTTTCATGCTACTTTAGAAGAGGCTATAGAGTCTGATCTTTTGGTACATGTTATAGATTATGCTGACGAGG
ATCATAAAAGCTACATTGAGCAGGTTGAAAAAGTACTCAGTGAAATTGGTATAGCAGACAAAGAGACGATTTGTGTCTAT
AACAAAATTGATAAATTAGAAAATATCAAGCCAAGTTTCGTGCCTCTTGAGGATTCTGATAGTAGCGTAGTTAGTAGGGT
ATATTTATCTGCACAAAATGGAGATGGTTTAGTAGAGTTTTATCAAGCATTAGCTACATTTTTTAATAAAACATGGATAA
ATCAAACTCTAGACTTACCGCCTAAATACTCAAAAGTCAGAGCTAAGATGTATGAGCTTGGTGTTATTGATAAAGAAGAG
ATTTCAGAACACGGTAACTATCTATTACAAATAAAAATATCACAAGATGATTTCGAGAGATTTAAAAGGGAACTTAATTT
AGATTTAGAAGAGTTCTTCGTTAAATAA

Upstream 100 bases:

>100_bases
TTCTGATGATCTTGAAATTCAAGAGAATGAAGGTAATATTCACGAGTAATATATCTTTTCTTTTTTCTTTAATAGTTCCA
TTGTGGAGTAATATTAGTTG

Downstream 100 bases:

>100_bases
TTGTTTAAGGTTATTCATACTCTGGAATTTGAATTGGATCATTAAATATCCCAGCACCGATAAATTTAGAAATAACAGGA
GTCGAAGATATCTTAACAGT

Product: protease, GTP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEFFQSYQAGSKCLLVNINFKYHRELNPDLTELEGLVIAAEKVVLQGLDFNHPEPDIKYFCGMGKIEMIKNKRDELEADL
VVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKTYEGKLQVELAQLNYQSTRLVKGWTHLERQKGGIGVRGGPG
ETQLEIDRRLIRQRIKQIAQKLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
RKVIVPKLGEIIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIEQVEKVLSEIGIADKETICVY
NKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEFYQALATFFNKTWINQTLDLPPKYSKVRAKMYELGVIDKEE
ISEHGNYLLQIKISQDDFERFKRELNLDLEEFFVK

Sequences:

>Translated_435_residues
MEFFQSYQAGSKCLLVNINFKYHRELNPDLTELEGLVIAAEKVVLQGLDFNHPEPDIKYFCGMGKIEMIKNKRDELEADL
VVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKTYEGKLQVELAQLNYQSTRLVKGWTHLERQKGGIGVRGGPG
ETQLEIDRRLIRQRIKQIAQKLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
RKVIVPKLGEIIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIEQVEKVLSEIGIADKETICVY
NKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEFYQALATFFNKTWINQTLDLPPKYSKVRAKMYELGVIDKEE
ISEHGNYLLQIKISQDDFERFKRELNLDLEEFFVK
>Mature_435_residues
MEFFQSYQAGSKCLLVNINFKYHRELNPDLTELEGLVIAAEKVVLQGLDFNHPEPDIKYFCGMGKIEMIKNKRDELEADL
VVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKTYEGKLQVELAQLNYQSTRLVKGWTHLERQKGGIGVRGGPG
ETQLEIDRRLIRQRIKQIAQKLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
RKVIVPKLGEIIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIEQVEKVLSEIGIADKETICVY
NKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEFYQALATFFNKTWINQTLDLPPKYSKVRAKMYELGVIDKEE
ISEHGNYLLQIKISQDDFERFKRELNLDLEEFFVK

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=362, Percent_Identity=29.2817679558011, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI310124269, Length=277, Percent_Identity=31.7689530685921, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI310124267, Length=277, Percent_Identity=31.7689530685921, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI310124171, Length=277, Percent_Identity=31.7689530685921, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI310124169, Length=277, Percent_Identity=31.7689530685921, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI310133116, Length=293, Percent_Identity=32.0819112627986, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI1790615, Length=422, Percent_Identity=49.7630331753554, Blast_Score=405, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17561038, Length=418, Percent_Identity=26.555023923445, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24650079, Length=390, Percent_Identity=30.2564102564103, Blast_Score=129, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50112; Mature: 50112

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFFQSYQAGSKCLLVNINFKYHRELNPDLTELEGLVIAAEKVVLQGLDFNHPEPDIKYF
CCHHHHHCCCCEEEEEEECEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
CGMGKIEMIKNKRDELEADLVVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKT
CCCCHHHHHHCCHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
YEGKLQVELAQLNYQSTRLVKGWTHLERQKGGIGVRGGPGETQLEIDRRLIRQRIKQIAQ
CCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEHHHHHHHCCHHH
RKVIVPKLGEIIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEHHHCCCHHHHHHH
QVEKVLSEIGIADKETICVYNKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEF
HHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCEEECCCCCHHHHHHHHEECCCCCCHHHH
YQALATFFNKTWINQTLDLPPKYSKVRAKMYELGVIDKEEISEHGNYLLQIKISQDDFER
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECHHHHHH
FKRELNLDLEEFFVK
HHHHHCCCHHHHHCC
>Mature Secondary Structure
MEFFQSYQAGSKCLLVNINFKYHRELNPDLTELEGLVIAAEKVVLQGLDFNHPEPDIKYF
CCHHHHHCCCCEEEEEEECEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
CGMGKIEMIKNKRDELEADLVVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKT
CCCCHHHHHHCCHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
YEGKLQVELAQLNYQSTRLVKGWTHLERQKGGIGVRGGPGETQLEIDRRLIRQRIKQIAQ
CCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEHHHHHHHCCHHH
RKVIVPKLGEIIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEHHHCCCHHHHHHH
QVEKVLSEIGIADKETICVYNKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEF
HHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCEEECCCCCHHHHHHHHEECCCCCCHHHH
YQALATFFNKTWINQTLDLPPKYSKVRAKMYELGVIDKEEISEHGNYLLQIKISQDDFER
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEECHHHHHH
FKRELNLDLEEFFVK
HHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]