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The map label for this gene is hflC [H]

Identifier: 89256261

GI number: 89256261

Start: 881066

End: 881992

Strand: Direct

Name: hflC [H]

Synonym: FTL_0904

Alternate gene names: 89256261

Gene position: 881066-881992 (Clockwise)

Preceding gene: 89256260

Following gene: 89256262

Centisome position: 46.47

GC content: 33.44

Gene sequence:

>927_bases
ATGAGTAAATTCCTAAAAATATTCTTATTGCTTGTAGTAGTCTTAGCTATAGTAGTATTAAGCACAAAATTTATTGTCAA
ACAAGGCTCAGAAGCAGTTATTCTAAGGCTTGGTGAACTTGTAAAGGATAAAGATGGCAAAGCTGTAGAGTATGAACCAG
GTTTACATATTAAAATCCCATTTATAGATACAGTTAAAATGTACGATATGCGTAACCGAGTTTTAGAGGCTGATTCTGCT
CGTGTAGTTACTAAAGAGCAAAAAGATGTACTGATTAATGCCTATGTGGTTTGGAAGATAAGTAATAACAATATTTCTAC
ATTTTACACAAGTACTAGTGGTAGTGTTGATCGAGCTGAGACATTATTAAAACAATTCTTGGAGTCTTCTTTAAGAGCAG
AGGTTGGTAATAATGATATTCAAAGTTTGATTAATAATAATCGTGATAAACTAATGATCGCTTTAACTAAGAGTGTCCAA
CAACAAGCTAAGCAAATCGGTGTAGATGTTATCGATGTGCGAGTAAAACAGATAGATTTACCTGAAACAGTTACAGATTC
TATCTACCAAAGAATGAGATCTTCTCGCCAAAAAGTAGCGGCTTCTATCCGTGCTGAAGGTAAGCAATTAGCTGAGAAAA
TAAAAGCTGCAGCAGATGCTAAAGTAACAGTTACATTAGCAGAAGCAGAAAAAGAATCAAAAACTATAATGGCAGAAGCA
GATGCCAAAGCAGCTAAGATTTTTACCCAAGCTTATTCTAAATCAATACCGTTATATGAGTTTCTAAAGAGTATGAACTC
CTATAAAGAGAGTTTTAACGGTAAGAATGAAGTCGTATTTATGCTTAAACCAGATAGTAAGTTTTTCCAAGGTTTTAAAT
TGGAACTAAATAGCAAACTTGCTGAAGATATGAAGGAAGCTAAATAA

Upstream 100 bases:

>100_bases
ATATTCTTGATAGATAGTGATGGTGCTAAGAATATTTTCTACGGTTTAAGTGATACACAAAAACAAGCACTATTATCAAA
TACGCAAGGAGGAAATTAAG

Downstream 100 bases:

>100_bases
ATGAGTAAAGTAAAAGTACTTTTTGTATGTAAAGGTAATATTTGTCGGTCGCCTACTGCACATAGTATTTTCCGTGATAT
TGTTAAGCAGTATAACTTAG

Product: SPFH domain-containing protein/band 7 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSKFLKIFLLLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIPFIDTVKMYDMRNRVLEADSA
RVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAETLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQ
QQAKQIGVDVIDVRVKQIDLPETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
DAKAAKIFTQAYSKSIPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLELNSKLAEDMKEAK

Sequences:

>Translated_308_residues
MSKFLKIFLLLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIPFIDTVKMYDMRNRVLEADSA
RVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAETLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQ
QQAKQIGVDVIDVRVKQIDLPETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
DAKAAKIFTQAYSKSIPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLELNSKLAEDMKEAK
>Mature_307_residues
SKFLKIFLLLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIPFIDTVKMYDMRNRVLEADSAR
VVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAETLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQQ
QAKQIGVDVIDVRVKQIDLPETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEAD
AKAAKIFTQAYSKSIPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLELNSKLAEDMKEAK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=310, Percent_Identity=36.7741935483871, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1786697, Length=256, Percent_Identity=23.4375, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 34590; Mature: 34458

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFLKIFLLLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEC
FIDTVKMYDMRNRVLEADSARVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAE
CCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEEEEEECCCEEEEEECCCCCHHHHH
TLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQQQAKQIGVDVIDVRVKQIDL
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCEEEEEEEEECCC
PETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECC
DAKAAKIFTQAYSKSIPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLELNSKL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCHHEEHHHHH
AEDMKEAK
HHHHHHCC
>Mature Secondary Structure 
SKFLKIFLLLVVVLAIVVLSTKFIVKQGSEAVILRLGELVKDKDGKAVEYEPGLHIKIP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEC
FIDTVKMYDMRNRVLEADSARVVTKEQKDVLINAYVVWKISNNNISTFYTSTSGSVDRAE
CCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEEEEEECCCEEEEEECCCCCHHHHH
TLLKQFLESSLRAEVGNNDIQSLINNNRDKLMIALTKSVQQQAKQIGVDVIDVRVKQIDL
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCEEEEEEEEECCC
PETVTDSIYQRMRSSRQKVAASIRAEGKQLAEKIKAAADAKVTVTLAEAEKESKTIMAEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECC
DAKAAKIFTQAYSKSIPLYEFLKSMNSYKESFNGKNEVVFMLKPDSKFFQGFKLELNSKL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCHHEEHHHHH
AEDMKEAK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]