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The map label for this gene is acdA [H]

Identifier: 89053818

GI number: 89053818

Start: 1291515

End: 1292666

Strand: Direct

Name: acdA [H]

Synonym: Jann_1327

Alternate gene names: 89053818

Gene position: 1291515-1292666 (Clockwise)

Preceding gene: 89053817

Following gene: 89053819

Centisome position: 29.91

GC content: 64.41

Gene sequence:

>1152_bases
ATGGCAGACAAATCGTTCCTCAGCTGGCCGTTTTTTGAAGAGCGGCACCGTGATCTGGCAGGCGCGCTTGATGCTTGGGC
GACGGCGGAGCTGGCCGGTATCGACCACAGCGATACCGATGCCGCCTGTCGCGCTTTGGTCGCTGCATTGGGGCAGGGGG
GCTGGCTGAACCATGCCGCCGTGAACCCAAAGGGCGAGGCCAAACTGGACGTGCGCACCCTGTGCCTGATCCGTGAAACA
CTGGCACGTCACGACGGGTTGGCGGATTTTGCTTTTGCGATGCAGGGCCTTGGGACCGGCGCGATCTCTCTGTTCGGGAC
GGATGCGCAGAAAGTCGAATGGCTGCCAAAGGTCCGCGCAGGCACCGCGATTTCCGCCTTCGCCCTGACGGAGCCGCAAT
CCGGCTCCGACGTCGCGAACTCCACCATGACGGCGACGCTGGACGGGGACGTTTATGTTCTGGACGGGGAGAAGACATGG
ATCAGCAATGGCGGCATCGCGGATGTCTACACGGTCTTTGCGCGCACCGGGGACGCGCCCGGCGCGCGGGGATTGTCGGC
CTTTGTCGTGCCTGCGGACGCGCCCGGTCTTGAGGTCACTGAACGGCTCGAGACCATCGCACCGCATCCCCTCTCCACCC
TCCGGTTCAGCGGGTGTCGTGTGCCCGCCTCCGCGCGTCTTGGCGAAAGCGGGGCGGGGTTTAAGATCGCCATGTCGGTC
CTTGATGTGTTCCGCTCAACAGTGGCGGCGGCGGCGCTTGGTTTCGCGCGGCGGGCACTGGATGAGGCGATGGCCCGCGT
CACCACCCGCCATGTCCAGGGCGCGCCGCTGTTTGATCTGCAAATGGTACAGGGTCACATCGCCGACATGGCCGTGGATA
TCGACGCGAGCGCGCTTCTGATCTACCGCGCCGCCTGGGCCAAGGATAGCGGCGCTCCGCGCGTGACGCGAGAGGCGGCG
ATGGCCAAGCTGTTCTCCACTGACCAGGCGCAAAAGGTCATTGACCGAGCCGTGCAATTGCATGGCGGAGACGGCGTCAG
GTCCGGCGAGACTGTTGAGAAACTCTACCGTGAAATCAGGGCGTTGCGCATCTATGAGGGTGCCTCGGACGTCCAGCGTG
TGATCATCGCGCGCCAGACGATCGGAGCGTAA

Upstream 100 bases:

>100_bases
CCGAGGCGCAGGCCCAGGCGATCTGCATGCAAACGGCGGATTTTGAGCGGGCCTACAAGGCCTTTGTCGCCAAGGAAAAA
CCAGTGTTCGAGGGCAATTG

Downstream 100 bases:

>100_bases
CCCATGCTAAGTGCCAGCGCCCATTCTGATACCTTCGCCCGCGATAACCTGCCCGCGCAGGACACGTGGCCAGAGTTTCT
GCTGGACGGCTTCGCCTATC

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MADKSFLSWPFFEERHRDLAGALDAWATAELAGIDHSDTDAACRALVAALGQGGWLNHAAVNPKGEAKLDVRTLCLIRET
LARHDGLADFAFAMQGLGTGAISLFGTDAQKVEWLPKVRAGTAISAFALTEPQSGSDVANSTMTATLDGDVYVLDGEKTW
ISNGGIADVYTVFARTGDAPGARGLSAFVVPADAPGLEVTERLETIAPHPLSTLRFSGCRVPASARLGESGAGFKIAMSV
LDVFRSTVAAAALGFARRALDEAMARVTTRHVQGAPLFDLQMVQGHIADMAVDIDASALLIYRAAWAKDSGAPRVTREAA
MAKLFSTDQAQKVIDRAVQLHGGDGVRSGETVEKLYREIRALRIYEGASDVQRVIIARQTIGA

Sequences:

>Translated_383_residues
MADKSFLSWPFFEERHRDLAGALDAWATAELAGIDHSDTDAACRALVAALGQGGWLNHAAVNPKGEAKLDVRTLCLIRET
LARHDGLADFAFAMQGLGTGAISLFGTDAQKVEWLPKVRAGTAISAFALTEPQSGSDVANSTMTATLDGDVYVLDGEKTW
ISNGGIADVYTVFARTGDAPGARGLSAFVVPADAPGLEVTERLETIAPHPLSTLRFSGCRVPASARLGESGAGFKIAMSV
LDVFRSTVAAAALGFARRALDEAMARVTTRHVQGAPLFDLQMVQGHIADMAVDIDASALLIYRAAWAKDSGAPRVTREAA
MAKLFSTDQAQKVIDRAVQLHGGDGVRSGETVEKLYREIRALRIYEGASDVQRVIIARQTIGA
>Mature_382_residues
ADKSFLSWPFFEERHRDLAGALDAWATAELAGIDHSDTDAACRALVAALGQGGWLNHAAVNPKGEAKLDVRTLCLIRETL
ARHDGLADFAFAMQGLGTGAISLFGTDAQKVEWLPKVRAGTAISAFALTEPQSGSDVANSTMTATLDGDVYVLDGEKTWI
SNGGIADVYTVFARTGDAPGARGLSAFVVPADAPGLEVTERLETIAPHPLSTLRFSGCRVPASARLGESGAGFKIAMSVL
DVFRSTVAAAALGFARRALDEAMARVTTRHVQGAPLFDLQMVQGHIADMAVDIDASALLIYRAAWAKDSGAPRVTREAAM
AKLFSTDQAQKVIDRAVQLHGGDGVRSGETVEKLYREIRALRIYEGASDVQRVIIARQTIGA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=338, Percent_Identity=39.3491124260355, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=34.0369393139842, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=34.0369393139842, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI76496475, Length=311, Percent_Identity=36.9774919614148, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI4557235, Length=311, Percent_Identity=36.9774919614148, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=30.9139784946237, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=30.5851063829787, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI226958414, Length=334, Percent_Identity=31.7365269461078, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI21361497, Length=294, Percent_Identity=34.3537414965986, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI4501859, Length=340, Percent_Identity=31.7647058823529, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI48976061, Length=294, Percent_Identity=35.0340136054422, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI211971008, Length=294, Percent_Identity=35.0340136054422, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4501857, Length=291, Percent_Identity=31.2714776632302, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI38505218, Length=322, Percent_Identity=29.1925465838509, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4503943, Length=361, Percent_Identity=27.1468144044321, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI7669494, Length=345, Percent_Identity=26.9565217391304, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI87081958, Length=268, Percent_Identity=31.7164179104478, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786223, Length=258, Percent_Identity=29.4573643410853, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87082384, Length=285, Percent_Identity=27.3684210526316, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=332, Percent_Identity=36.7469879518072, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17569725, Length=291, Percent_Identity=35.7388316151203, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71985184, Length=293, Percent_Identity=36.518771331058, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=306, Percent_Identity=36.9281045751634, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17570075, Length=318, Percent_Identity=34.2767295597484, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17533517, Length=280, Percent_Identity=33.2142857142857, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=309, Percent_Identity=34.6278317152104, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=29.700272479564, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=227, Percent_Identity=37.4449339207048, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=240, Percent_Identity=35.4166666666667, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17505929, Length=285, Percent_Identity=29.8245614035088, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=285, Percent_Identity=29.4736842105263, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17531909, Length=238, Percent_Identity=30.672268907563, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=181, Percent_Identity=32.0441988950276, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=28.1818181818182, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=288, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=224, Percent_Identity=30.3571428571429, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=313, Percent_Identity=26.517571884984, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=313, Percent_Identity=26.517571884984, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531913, Length=168, Percent_Identity=29.7619047619048, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=36.7567567567568, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24660351, Length=331, Percent_Identity=37.7643504531722, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=35.0132625994695, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24666513, Length=337, Percent_Identity=32.3442136498516, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI281363737, Length=294, Percent_Identity=34.0136054421769, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21355753, Length=351, Percent_Identity=31.3390313390313, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI19920834, Length=318, Percent_Identity=30.188679245283, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40636; Mature: 40505

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKSFLSWPFFEERHRDLAGALDAWATAELAGIDHSDTDAACRALVAALGQGGWLNHAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
VNPKGEAKLDVRTLCLIRETLARHDGLADFAFAMQGLGTGAISLFGTDAQKVEWLPKVRA
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCC
GTAISAFALTEPQSGSDVANSTMTATLDGDVYVLDGEKTWISNGGIADVYTVFARTGDAP
CCEEEEEEECCCCCCCCCCCCCEEEEECCCEEEECCCEEEECCCCHHHHHHHHHHCCCCC
GARGLSAFVVPADAPGLEVTERLETIAPHPLSTLRFSGCRVPASARLGESGAGFKIAMSV
CCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHEECCCCCCHHCCCCCCCCCHHHHHHH
LDVFRSTVAAAALGFARRALDEAMARVTTRHVQGAPLFDLQMVQGHIADMAVDIDASALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCCCEEE
IYRAAWAKDSGAPRVTREAAMAKLFSTDQAQKVIDRAVQLHGGDGVRSGETVEKLYREIR
EEHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALRIYEGASDVQRVIIARQTIGA
HHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADKSFLSWPFFEERHRDLAGALDAWATAELAGIDHSDTDAACRALVAALGQGGWLNHAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
VNPKGEAKLDVRTLCLIRETLARHDGLADFAFAMQGLGTGAISLFGTDAQKVEWLPKVRA
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCC
GTAISAFALTEPQSGSDVANSTMTATLDGDVYVLDGEKTWISNGGIADVYTVFARTGDAP
CCEEEEEEECCCCCCCCCCCCCEEEEECCCEEEECCCEEEECCCCHHHHHHHHHHCCCCC
GARGLSAFVVPADAPGLEVTERLETIAPHPLSTLRFSGCRVPASARLGESGAGFKIAMSV
CCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHEECCCCCCHHCCCCCCCCCHHHHHHH
LDVFRSTVAAAALGFARRALDEAMARVTTRHVQGAPLFDLQMVQGHIADMAVDIDASALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCCCEEE
IYRAAWAKDSGAPRVTREAAMAKLFSTDQAQKVIDRAVQLHGGDGVRSGETVEKLYREIR
EEHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALRIYEGASDVQRVIIARQTIGA
HHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]