Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 89053814

GI number: 89053814

Start: 1287214

End: 1289508

Strand: Direct

Name: namA [H]

Synonym: Jann_1323

Alternate gene names: 89053814

Gene position: 1287214-1289508 (Clockwise)

Preceding gene: 89053813

Following gene: 89053815

Centisome position: 29.81

GC content: 60.48

Gene sequence:

>2295_bases
ATGCGGATAGCGTGCCTTGGCGGGGGACCAGCGGGCCTCTACTTTGCGATTTCCACGAAGCTGCGGACGCCGGATGCAGA
GGTTGTCGTGCTAGAGCGCAACAAGCCGGACGACACCTTTGGTTGGGGCGTTGTCCTGTCCGATGAAACCCTTGCAAACC
TTGACGTTAACGACCCGGTGAGCGCGGCGAAGATCAAGTCGCACTTCGCCTATTGGGACGACATCGCGCTGCATCACAAG
GGGCAGAAGCTGGTATCAAGCGGCCATGGATTCTGCGGCATCGGCCGTAAGACATTGCTGTTGATCCTGCATGAACGCGC
CCGCGAGTTGGGCGTCGATCTGCGGTTCGAGACCGAGGTTAAGGCGGCCTTTGACTATATGGAGGAGTACGATGTCGTTG
TGGCTTGCGATGGTCTGAATTCCAAAACGCGATTGGAATTTGCAGACAGCTTCCAGCCCGATATCGACACCCGTTTGTGT
CCGTTTGTCTGGCTTGGCACGCACCAGAAATTCGATGACGCGTTTACCTTCATTTTTGAAGAGACGGACAAAGGCTGGAT
CTGGGTCCATGCTTATCAGTTCGATGACGATACGGCGACGTTCATCGTGGAATGCAGTCAGGAGACGTTTGACGCCTACG
GGTTCGGTGAGATGAGCCAACAGGACAGCATCGCCGTCTGCGAGGAGATCTTCAAAGACCACCTTGACGGCCATTCATTG
ATGACCAACGCCAACCACATTCGCGGCTCAGCCTGGATCCGTTTCCCGCGCGTGTTGTGTGAAAAGTGGAGCCACGAAAA
CGTGGTTCTGCTGGGGGATGCGTCCGCTACGGCGCACTTCTCCATCGGGTCCGGCACGAAGCTGGCATTGGAAAGCGCGA
TTGCCCTGGCAGATGACATCGAGACCCAGCCGACGCTGGAGGCCGCCTTTGCCAACTACGAGGACAAGCGCCGCCTGGAA
GTGCTGCGCCTGCAATCGGCGGCACGCAACTCGGTTGAGTGGTTCGAGGATGTGGAACGGTATCTGCATCTGGACCCGGT
GCAGCTGAACTATTCCATGCTGACCCGCTCCCAGCGGATCAGCCATGAAAACCTGCGGGAACGGGATGCAGACTGGCTTG
GTTCGGCTGAGGAGTGGTTCATGAGCCAGGCGGGCGTGACGTCCAATGGGAAAGCCCGCGCGCCAATGTTCGCGCCGTTC
CGATTGCGCGACATGCATCTGAAGAACCGCATCGTCGTCTCGCCGATGGCGCAATATAAGGCCGTGGACGGCGCGCCAAC
CGATTGGCACCTGATCCACTATGGTGAGCGTGCGAAGGGCGGTGCGGGTCTGGTTTATACGGAAATGACCTGCGTGTCGG
CGGAAGGGCGGATCACCCCCGGATGCCCCGGCCTCTATGCGCCGGACCATGAGGCGGCCTGGACCCGGTTGAACGCCTTC
GTCCACTCTGAAACGGAAGCGATGACCTGCTGCCAAATCGGTCACGCAGGGCGGAAAGGCTCCACCCGGATCGGGTGGGA
GGGCATGGATCACCCCCTGGCCGAGGGCAACTGGCCCCTTCTGTCGGCCTCCGCCATTCCATGGTCCAATGAGAATGCGA
TGCCCAAGGCGATGGATCGCGGGGATATGGACGCGGTGAAAGCCGAGTTCGTGTCTGCCACGCAGATGGCAGATCGCGCG
GGGTTTGACATGGTCGAGCTGCACGCGGCCCACGGGTATCTGATCTCGTCGTTCATCTCTCCGCTGTCGAATGCGCGCAC
GGATGACTACGGCGGCAGCCTGGAAAACCGTATGCGCTATCCGTTGGAGGTCTTTGACGCGATGCGTGCGGTCTGGCCCG
AGGGCAAGCCGATGTCCGTGCGGATCTCGGCCAGTGATTGGGCGGGCGACGACGGTGTGACCGCGGAGGAGGCCGTGCAG
ATTGCGGCGATGTTTGAAGCCGCAGGGGCCGATATCATTGACGTGTCCGCGGGCCAGACCTCTACCCAGGGCAAGCCTGT
CTATGGTCGCATGTTTCAGACCCCGTTGTCGGACCGCATCCGCAATGAGGCGGGCATCAAGACGATGGCCGTCGGGAACA
TTTATGAGGCCGATCACGTGAACTCCATTCTGATGGCGGGCCGGGCCGATCTGGTGTGTATCGCACGCCCGCATCTGGCC
GACCCCTACTGGACCTTGCACGCGGCCACTGGCCTCGGAGACCGACAGGAGGTCTGGCTAAAACCCTATGAGGCGGGTCG
AGATCAGGCGTGGCGAAATGCGGACCGGGATGCCGAGATGGTGGGCAAGGTATGA

Upstream 100 bases:

>100_bases
TGCGAGCCATATATACTTCAAGTATAAAATATTTGGACTTGAAGTAGTGGGTGATCCGGCCTAGCGTAGCTTGAAACACA
GTCTGTGGAGGGGCGATCAG

Downstream 100 bases:

>100_bases
CGTCCCATGTGGTGATCTCCGGCGGCGGCACGGGTGTGGGCGCGGAGACCGCGAAGCAGTTCGCGCAGGCGGGCTACGCC
GTGACGATCCTGGGCCGAAC

Product: salicylyl-CoA 5-hydroxylase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MRIACLGGGPAGLYFAISTKLRTPDAEVVVLERNKPDDTFGWGVVLSDETLANLDVNDPVSAAKIKSHFAYWDDIALHHK
GQKLVSSGHGFCGIGRKTLLLILHERARELGVDLRFETEVKAAFDYMEEYDVVVACDGLNSKTRLEFADSFQPDIDTRLC
PFVWLGTHQKFDDAFTFIFEETDKGWIWVHAYQFDDDTATFIVECSQETFDAYGFGEMSQQDSIAVCEEIFKDHLDGHSL
MTNANHIRGSAWIRFPRVLCEKWSHENVVLLGDASATAHFSIGSGTKLALESAIALADDIETQPTLEAAFANYEDKRRLE
VLRLQSAARNSVEWFEDVERYLHLDPVQLNYSMLTRSQRISHENLRERDADWLGSAEEWFMSQAGVTSNGKARAPMFAPF
RLRDMHLKNRIVVSPMAQYKAVDGAPTDWHLIHYGERAKGGAGLVYTEMTCVSAEGRITPGCPGLYAPDHEAAWTRLNAF
VHSETEAMTCCQIGHAGRKGSTRIGWEGMDHPLAEGNWPLLSASAIPWSNENAMPKAMDRGDMDAVKAEFVSATQMADRA
GFDMVELHAAHGYLISSFISPLSNARTDDYGGSLENRMRYPLEVFDAMRAVWPEGKPMSVRISASDWAGDDGVTAEEAVQ
IAAMFEAAGADIIDVSAGQTSTQGKPVYGRMFQTPLSDRIRNEAGIKTMAVGNIYEADHVNSILMAGRADLVCIARPHLA
DPYWTLHAATGLGDRQEVWLKPYEAGRDQAWRNADRDAEMVGKV

Sequences:

>Translated_764_residues
MRIACLGGGPAGLYFAISTKLRTPDAEVVVLERNKPDDTFGWGVVLSDETLANLDVNDPVSAAKIKSHFAYWDDIALHHK
GQKLVSSGHGFCGIGRKTLLLILHERARELGVDLRFETEVKAAFDYMEEYDVVVACDGLNSKTRLEFADSFQPDIDTRLC
PFVWLGTHQKFDDAFTFIFEETDKGWIWVHAYQFDDDTATFIVECSQETFDAYGFGEMSQQDSIAVCEEIFKDHLDGHSL
MTNANHIRGSAWIRFPRVLCEKWSHENVVLLGDASATAHFSIGSGTKLALESAIALADDIETQPTLEAAFANYEDKRRLE
VLRLQSAARNSVEWFEDVERYLHLDPVQLNYSMLTRSQRISHENLRERDADWLGSAEEWFMSQAGVTSNGKARAPMFAPF
RLRDMHLKNRIVVSPMAQYKAVDGAPTDWHLIHYGERAKGGAGLVYTEMTCVSAEGRITPGCPGLYAPDHEAAWTRLNAF
VHSETEAMTCCQIGHAGRKGSTRIGWEGMDHPLAEGNWPLLSASAIPWSNENAMPKAMDRGDMDAVKAEFVSATQMADRA
GFDMVELHAAHGYLISSFISPLSNARTDDYGGSLENRMRYPLEVFDAMRAVWPEGKPMSVRISASDWAGDDGVTAEEAVQ
IAAMFEAAGADIIDVSAGQTSTQGKPVYGRMFQTPLSDRIRNEAGIKTMAVGNIYEADHVNSILMAGRADLVCIARPHLA
DPYWTLHAATGLGDRQEVWLKPYEAGRDQAWRNADRDAEMVGKV
>Mature_764_residues
MRIACLGGGPAGLYFAISTKLRTPDAEVVVLERNKPDDTFGWGVVLSDETLANLDVNDPVSAAKIKSHFAYWDDIALHHK
GQKLVSSGHGFCGIGRKTLLLILHERARELGVDLRFETEVKAAFDYMEEYDVVVACDGLNSKTRLEFADSFQPDIDTRLC
PFVWLGTHQKFDDAFTFIFEETDKGWIWVHAYQFDDDTATFIVECSQETFDAYGFGEMSQQDSIAVCEEIFKDHLDGHSL
MTNANHIRGSAWIRFPRVLCEKWSHENVVLLGDASATAHFSIGSGTKLALESAIALADDIETQPTLEAAFANYEDKRRLE
VLRLQSAARNSVEWFEDVERYLHLDPVQLNYSMLTRSQRISHENLRERDADWLGSAEEWFMSQAGVTSNGKARAPMFAPF
RLRDMHLKNRIVVSPMAQYKAVDGAPTDWHLIHYGERAKGGAGLVYTEMTCVSAEGRITPGCPGLYAPDHEAAWTRLNAF
VHSETEAMTCCQIGHAGRKGSTRIGWEGMDHPLAEGNWPLLSASAIPWSNENAMPKAMDRGDMDAVKAEFVSATQMADRA
GFDMVELHAAHGYLISSFISPLSNARTDDYGGSLENRMRYPLEVFDAMRAVWPEGKPMSVRISASDWAGDDGVTAEEAVQ
IAAMFEAAGADIIDVSAGQTSTQGKPVYGRMFQTPLSDRIRNEAGIKTMAVGNIYEADHVNSILMAGRADLVCIARPHLA
DPYWTLHAATGLGDRQEVWLKPYEAGRDQAWRNADRDAEMVGKV

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=236, Percent_Identity=34.3220338983051, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789463, Length=367, Percent_Identity=27.5204359673025, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=246, Percent_Identity=31.7073170731707, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=247, Percent_Identity=30.7692307692308, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=243, Percent_Identity=30.8641975308642, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17559804, Length=246, Percent_Identity=30.8943089430894, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=246, Percent_Identity=30.0813008130081, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=245, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=307, Percent_Identity=25.7328990228013, Blast_Score=94, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=273, Percent_Identity=29.6703296703297, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6325086, Length=232, Percent_Identity=28.0172413793103, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 84875; Mature: 84875

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIACLGGGPAGLYFAISTKLRTPDAEVVVLERNKPDDTFGWGVVLSDETLANLDVNDPV
CEEEEECCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCCCEECCCCCCCC
SAAKIKSHFAYWDDIALHHKGQKLVSSGHGFCGIGRKTLLLILHERARELGVDLRFETEV
HHHHHHHHHHHHHCEEECCCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCEEEECHH
KAAFDYMEEYDVVVACDGLNSKTRLEFADSFQPDIDTRLCPFVWLGTHQKFDDAFTFIFE
HHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEE
ETDKGWIWVHAYQFDDDTATFIVECSQETFDAYGFGEMSQQDSIAVCEEIFKDHLDGHSL
ECCCCEEEEEEEEECCCCEEEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
MTNANHIRGSAWIRFPRVLCEKWSHENVVLLGDASATAHFSIGSGTKLALESAIALADDI
ECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCC
ETQPTLEAAFANYEDKRRLEVLRLQSAARNSVEWFEDVERYLHLDPVQLNYSMLTRSQRI
CCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHC
SHENLRERDADWLGSAEEWFMSQAGVTSNGKARAPMFAPFRLRDMHLKNRIVVSPMAQYK
CHHHHHHHCHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCEEECHHHCCEEEECCHHHHH
AVDGAPTDWHLIHYGERAKGGAGLVYTEMTCVSAEGRITPGCPGLYAPDHEAAWTRLNAF
CCCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
VHSETEAMTCCQIGHAGRKGSTRIGWEGMDHPLAEGNWPLLSASAIPWSNENAMPKAMDR
HCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GDMDAVKAEFVSATQMADRAGFDMVELHAAHGYLISSFISPLSNARTDDYGGSLENRMRY
CCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
PLEVFDAMRAVWPEGKPMSVRISASDWAGDDGVTAEEAVQIAAMFEAAGADIIDVSAGQT
CHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
STQGKPVYGRMFQTPLSDRIRNEAGIKTMAVGNIYEADHVNSILMAGRADLVCIARPHLA
CCCCCCCCHHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCC
DPYWTLHAATGLGDRQEVWLKPYEAGRDQAWRNADRDAEMVGKV
CCCEEEEEECCCCCCHHEEECCCCCCCCHHHHCCCCCHHHHCCC
>Mature Secondary Structure
MRIACLGGGPAGLYFAISTKLRTPDAEVVVLERNKPDDTFGWGVVLSDETLANLDVNDPV
CEEEEECCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCCCEECCCCCCCC
SAAKIKSHFAYWDDIALHHKGQKLVSSGHGFCGIGRKTLLLILHERARELGVDLRFETEV
HHHHHHHHHHHHHCEEECCCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCEEEECHH
KAAFDYMEEYDVVVACDGLNSKTRLEFADSFQPDIDTRLCPFVWLGTHQKFDDAFTFIFE
HHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEE
ETDKGWIWVHAYQFDDDTATFIVECSQETFDAYGFGEMSQQDSIAVCEEIFKDHLDGHSL
ECCCCEEEEEEEEECCCCEEEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
MTNANHIRGSAWIRFPRVLCEKWSHENVVLLGDASATAHFSIGSGTKLALESAIALADDI
ECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCC
ETQPTLEAAFANYEDKRRLEVLRLQSAARNSVEWFEDVERYLHLDPVQLNYSMLTRSQRI
CCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHC
SHENLRERDADWLGSAEEWFMSQAGVTSNGKARAPMFAPFRLRDMHLKNRIVVSPMAQYK
CHHHHHHHCHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCEEECHHHCCEEEECCHHHHH
AVDGAPTDWHLIHYGERAKGGAGLVYTEMTCVSAEGRITPGCPGLYAPDHEAAWTRLNAF
CCCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
VHSETEAMTCCQIGHAGRKGSTRIGWEGMDHPLAEGNWPLLSASAIPWSNENAMPKAMDR
HCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GDMDAVKAEFVSATQMADRAGFDMVELHAAHGYLISSFISPLSNARTDDYGGSLENRMRY
CCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
PLEVFDAMRAVWPEGKPMSVRISASDWAGDDGVTAEEAVQIAAMFEAAGADIIDVSAGQT
CHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
STQGKPVYGRMFQTPLSDRIRNEAGIKTMAVGNIYEADHVNSILMAGRADLVCIARPHLA
CCCCCCCCHHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCC
DPYWTLHAATGLGDRQEVWLKPYEAGRDQAWRNADRDAEMVGKV
CCCEEEEEECCCCCCHHEEECCCCCCCCHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA