BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

Click here to switch to the map view.

The map label for this gene is bdhA [H]

Identifier: 89053815

GI number: 89053815

Start: 1289505

End: 1290239

Strand: Direct

Name: bdhA [H]

Synonym: Jann_1324

Alternate gene names: 89053815

Gene position: 1289505-1290239 (Clockwise)

Preceding gene: 89053814

Following gene: 89053816

Centisome position: 29.86

GC content: 64.22

Gene sequence:

>735_bases
ATGACGTCCCATGTGGTGATCTCCGGCGGCGGCACGGGTGTGGGCGCGGAGACCGCGAAGCAGTTCGCGCAGGCGGGCTA
CGCCGTGACGATCCTGGGCCGAACCGAGGCGACGTTGCAGGCGCAGGGGCTGGCCTATCAGGTGTGCGATGTCACGGACG
ACGTCGCCGTCAAACGCGCCATGGAAGCTGCCCGGTCAGCACGAGGTCCGATCAGCGTGGTGATCGCCAATGCCGGTGCC
GCGACCTCCCAACCCTTCGCCAAGATGACCGCCGCCGATCTGTCGGCGATGACCGATGTAAACCTGACGGGCGTGTTCAA
CCTGTGGCAGGCGGCTTTGCCGGATATGAAGGCCGCCAAGCAGGGCCGCATGATCGCGATTGCCTCAACCGCTGGCCTCA
AGGGCTACCCTTATGTGGCGGGCTACTGCGCGGCCAAACATGGCGTTATCGGTCTGACGCGCGCCCTGGCGCTGGAACTG
GCCATGTCCGGCATCACGGTCAACGCCATTTGCCCGGGTTTCATTGAAACGCCGCTTCTGGACCGCTCCATCACCAACAT
CGTTGAGAAAACGGGGATGAGCGTGGACGCCGCCGCCAAGTCCTTGACGAAGGGCAACCCGCAGCGCCGCTTCATTCAGA
CCGACGAGGTCGCAGCAACCGCGCTTTGGCTGTGCTCAGACGCTGCAAAATCGGTAAACGGCCATGCCCTTAGCCTGTCG
GGGGGGGAGATCTGA

Upstream 100 bases:

>100_bases
GCCTCGGAGACCGACAGGAGGTCTGGCTAAAACCCTATGAGGCGGGTCGAGATCAGGCGTGGCGAAATGCGGACCGGGAT
GCCGAGATGGTGGGCAAGGT

Downstream 100 bases:

>100_bases
TGCAAACGGATGAACGTACCGCGCCGGAGACCCTGTCGAAGGAACGGTTGCGCTTGTGGCTTCGATTTCTGAAAGCCAGC
CGTTCGATTGAGAGCGTTCT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTSHVVISGGGTGVGAETAKQFAQAGYAVTILGRTEATLQAQGLAYQVCDVTDDVAVKRAMEAARSARGPISVVIANAGA
ATSQPFAKMTAADLSAMTDVNLTGVFNLWQAALPDMKAAKQGRMIAIASTAGLKGYPYVAGYCAAKHGVIGLTRALALEL
AMSGITVNAICPGFIETPLLDRSITNIVEKTGMSVDAAAKSLTKGNPQRRFIQTDEVAATALWLCSDAAKSVNGHALSLS
GGEI

Sequences:

>Translated_244_residues
MTSHVVISGGGTGVGAETAKQFAQAGYAVTILGRTEATLQAQGLAYQVCDVTDDVAVKRAMEAARSARGPISVVIANAGA
ATSQPFAKMTAADLSAMTDVNLTGVFNLWQAALPDMKAAKQGRMIAIASTAGLKGYPYVAGYCAAKHGVIGLTRALALEL
AMSGITVNAICPGFIETPLLDRSITNIVEKTGMSVDAAAKSLTKGNPQRRFIQTDEVAATALWLCSDAAKSVNGHALSLS
GGEI
>Mature_243_residues
TSHVVISGGGTGVGAETAKQFAQAGYAVTILGRTEATLQAQGLAYQVCDVTDDVAVKRAMEAARSARGPISVVIANAGAA
TSQPFAKMTAADLSAMTDVNLTGVFNLWQAALPDMKAAKQGRMIAIASTAGLKGYPYVAGYCAAKHGVIGLTRALALELA
MSGITVNAICPGFIETPLLDRSITNIVEKTGMSVDAAAKSLTKGNPQRRFIQTDEVAATALWLCSDAAKSVNGHALSLSG
GEI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=27.9835390946502, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI210032110, Length=214, Percent_Identity=26.1682242990654, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=29.8429319371728, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7706318, Length=214, Percent_Identity=26.6355140186916, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=25.3968253968254, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=27.1604938271605, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=24.6153846153846, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI210032112, Length=204, Percent_Identity=25, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI4758504, Length=203, Percent_Identity=30.5418719211823, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=30.6034482758621, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=26.953125, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=31.0160427807487, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4504505, Length=256, Percent_Identity=26.953125, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=226, Percent_Identity=26.9911504424779, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI223718074, Length=207, Percent_Identity=27.536231884058, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=26.1224489795918, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI31542939, Length=148, Percent_Identity=29.0540540540541, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=26.5060240963855, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=190, Percent_Identity=24.7368421052632, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=31.3253012048193, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=31.4516129032258, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=30.4878048780488, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=30.4878048780488, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=28.7449392712551, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=29.3172690763052, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI2367175, Length=263, Percent_Identity=29.6577946768061, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=27.2373540856031, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786812, Length=240, Percent_Identity=26.25, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=24, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=30.8943089430894, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=29.6, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567345, Length=188, Percent_Identity=29.2553191489362, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=24.8, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=26.4227642276423, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=28.042328042328, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=26.8199233716475, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=28.042328042328, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=29.0196078431373, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=190, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=182, Percent_Identity=30.2197802197802, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=25.2631578947368, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=24.2307692307692, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=208, Percent_Identity=27.8846153846154, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=189, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=194, Percent_Identity=27.8350515463918, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=185, Percent_Identity=36.7567567567568, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=29.4736842105263, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=186, Percent_Identity=28.494623655914, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=200, Percent_Identity=30.5, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=29.0983606557377, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=28.515625, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=28.0632411067194, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640492, Length=188, Percent_Identity=31.3829787234043, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=28.0487804878049, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI18859837, Length=185, Percent_Identity=31.3513513513514, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=33.7349397590361, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=28.042328042328, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=27.8225806451613, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584752, Length=231, Percent_Identity=29.004329004329, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24649181, Length=186, Percent_Identity=27.9569892473118, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357673, Length=189, Percent_Identity=31.2169312169312, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648944, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221510726, Length=164, Percent_Identity=29.8780487804878, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=30.6930693069307, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=30.6930693069307, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24665264, Length=256, Percent_Identity=30.859375, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 25018; Mature: 24887

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSHVVISGGGTGVGAETAKQFAQAGYAVTILGRTEATLQAQGLAYQVCDVTDDVAVKRA
CCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEECCCEEEECCCCHHHHHHHH
MEAARSARGPISVVIANAGAATSQPFAKMTAADLSAMTDVNLTGVFNLWQAALPDMKAAK
HHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHH
QGRMIAIASTAGLKGYPYVAGYCAAKHGVIGLTRALALELAMSGITVNAICPGFIETPLL
CCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCHHHCCHH
DRSITNIVEKTGMSVDAAAKSLTKGNPQRRFIQTDEVAATALWLCSDAAKSVNGHALSLS
HHHHHHHHHHHCCCHHHHHHHHHCCCCHHHEEEHHHHHHHHHHHHHHHHHCCCCCEEECC
GGEI
CCCC
>Mature Secondary Structure 
TSHVVISGGGTGVGAETAKQFAQAGYAVTILGRTEATLQAQGLAYQVCDVTDDVAVKRA
CCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEECCCEEEECCCCHHHHHHHH
MEAARSARGPISVVIANAGAATSQPFAKMTAADLSAMTDVNLTGVFNLWQAALPDMKAAK
HHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHH
QGRMIAIASTAGLKGYPYVAGYCAAKHGVIGLTRALALELAMSGITVNAICPGFIETPLL
CCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCHHHCCHH
DRSITNIVEKTGMSVDAAAKSLTKGNPQRRFIQTDEVAATALWLCSDAAKSVNGHALSLS
HHHHHHHHHHHCCCHHHHHHHHHCCCCHHHEEEHHHHHHHHHHHHHHHHHCCCCCEEECC
GGEI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]